AU1246995A - Alpha-quaternary-alpha-amino acids for use as cns agents - Google Patents
Alpha-quaternary-alpha-amino acids for use as cns agentsInfo
- Publication number
- AU1246995A AU1246995A AU12469/95A AU1246995A AU1246995A AU 1246995 A AU1246995 A AU 1246995A AU 12469/95 A AU12469/95 A AU 12469/95A AU 1246995 A AU1246995 A AU 1246995A AU 1246995 A AU1246995 A AU 1246995A
- Authority
- AU
- Australia
- Prior art keywords
- alpha
- quaternary
- amino acids
- cns agents
- cns
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/24—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having more than one carboxyl group bound to the carbon skeleton, e.g. aspartic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/28—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/57—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing carboxyl groups bound to the carbon skeleton
- C07C309/61—Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing carboxyl groups bound to the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9325368 | 1993-12-10 | ||
| GB939325368A GB9325368D0 (en) | 1993-12-10 | 1993-12-10 | Organic compounds |
| PCT/GB1994/002690 WO1995015940A1 (en) | 1993-12-10 | 1994-12-09 | Alpha-quaternary-alpha-amino acids for use as cns agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU1246995A true AU1246995A (en) | 1995-06-27 |
Family
ID=10746453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU12469/95A Abandoned AU1246995A (en) | 1993-12-10 | 1994-12-09 | Alpha-quaternary-alpha-amino acids for use as cns agents |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0733036A1 (en) |
| AU (1) | AU1246995A (en) |
| GB (1) | GB9325368D0 (en) |
| WO (1) | WO1995015940A1 (en) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL182285B1 (en) * | 1994-08-12 | 2001-12-31 | Lilly Co Eli | Synthetic amino acids and their esters and pharmaceutical preparations containing them. PL PL PL PL PL PL PL |
| US5661184A (en) * | 1994-08-12 | 1997-08-26 | Eli Lilly And Company | Psychiatric agents |
| ES2162936T3 (en) * | 1994-08-12 | 2002-01-16 | Lilly Co Eli | TREATMENT OF ANXIETY. |
| NZ291597A (en) * | 1994-09-08 | 1998-12-23 | Lilly Co Eli | Carboxycyclopropan-1-yl derivatives, preparation, pharmaceutical compositions and intermediates thereof |
| US5717109A (en) * | 1994-09-08 | 1998-02-10 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
| IL118727A (en) * | 1995-06-29 | 2003-01-12 | Lilly Co Eli | (-)-2-spiro-5-hydantoinbicyclo [3.1.0] hexane-6-carboxylic acid, salts thereof and use thereof for the preparation of (+)-(2) aminobicyclo [3.1.0] hexane-2,6-dicarboxylic acid |
| US5688826A (en) * | 1995-11-16 | 1997-11-18 | Eli Lilly And Company | Excitatory amino acid derivatives |
| US5912248A (en) * | 1995-11-16 | 1999-06-15 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
| ZA969485B (en) * | 1995-11-16 | 1998-05-12 | Lilly Co Eli | Excitatory amino acid receptor antagonists. |
| GB9617822D0 (en) * | 1996-08-27 | 1996-10-09 | Lilly Industries Ltd | Pharmaceutical compounds |
| GB9621789D0 (en) * | 1996-10-18 | 1996-12-11 | Lilly Industries Ltd | Pharmaceutical compounds |
| ES2131463B1 (en) * | 1997-04-08 | 2000-03-01 | Lilly Sa | DERIVATIVES OF CYCLOPROPYLGLYCIN WITH PHARMACEUTICAL PROPERTIES. |
| US6825211B1 (en) | 1997-07-18 | 2004-11-30 | Georgetown University | Bicyclic metabotropic glutamate receptor ligands |
| US6204292B1 (en) * | 1997-07-18 | 2001-03-20 | Georgetown University | Bicyclic metabotropic glutamate receptor ligands |
| DE19801636A1 (en) | 1998-01-17 | 1999-07-22 | Bayer Ag | New bi:cyclic lactone glutamate receptor modulators |
| DE19801647A1 (en) | 1998-01-17 | 1999-07-22 | Bayer Ag | New beta, gamma-fused lactone glutamate receptor modulators for treating cerebral ischemia, cranial or brain trauma, pain or CNS-mediated spasms |
| DE19801646A1 (en) | 1998-01-17 | 1999-07-22 | Bayer Ag | New bicyclic lactone glutamate receptor modulators for treating cerebral ischemia, cranial/brain trauma, pain or CNS-mediated spasms |
| CA2306170A1 (en) * | 2000-04-18 | 2001-10-18 | Kenneth Curry | Novel amino, carboxy derivatives of barbituric acid |
| CN101166524B (en) | 2005-04-28 | 2010-12-22 | 辉瑞有限公司 | Amino acid derivatives |
| EP1937699A2 (en) * | 2005-10-18 | 2008-07-02 | Centre National De La Recherche Scientifique (Cnrs) | Hypophosphorous acid derivatives and their therapeutical applications |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2658912A (en) * | 1951-12-28 | 1953-11-10 | Merck & Co Inc | Alpha-methyl glutamic acid and salts and process for preparation |
| FR2392958A1 (en) * | 1977-06-01 | 1978-12-29 | Merck & Co Inc | NEW FLUORINE AMINO ACIDS USEFUL AS A MEDICINAL PRODUCT |
| US4133964A (en) * | 1977-07-01 | 1979-01-09 | Merrell Toraude Et Compagnie | α-Acetylenic derivatives of α-amino acids |
| US4260823A (en) * | 1979-07-02 | 1981-04-07 | Merrell Toruade Et Compagnie | α-Acetylenic derivatives of α-amino acids |
| CA2025326C (en) * | 1989-09-19 | 2001-04-24 | Jeffrey P. Whitten | Nmda antagonists |
-
1993
- 1993-12-10 GB GB939325368A patent/GB9325368D0/en active Pending
-
1994
- 1994-12-09 EP EP95903410A patent/EP0733036A1/en not_active Withdrawn
- 1994-12-09 AU AU12469/95A patent/AU1246995A/en not_active Abandoned
- 1994-12-09 WO PCT/GB1994/002690 patent/WO1995015940A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO1995015940A1 (en) | 1995-06-15 |
| GB9325368D0 (en) | 1994-02-16 |
| EP0733036A1 (en) | 1996-09-25 |
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