ATE527053T1 - Syntheseeinrichtung für oligonukleotide unter nutzung von fliehkraft - Google Patents
Syntheseeinrichtung für oligonukleotide unter nutzung von fliehkraftInfo
- Publication number
- ATE527053T1 ATE527053T1 AT00988097T AT00988097T ATE527053T1 AT E527053 T1 ATE527053 T1 AT E527053T1 AT 00988097 T AT00988097 T AT 00988097T AT 00988097 T AT00988097 T AT 00988097T AT E527053 T1 ATE527053 T1 AT E527053T1
- Authority
- AT
- Austria
- Prior art keywords
- liquid
- vessel
- aperture
- combinatorial
- orbiting
- Prior art date
Links
- 238000003786 synthesis reaction Methods 0.000 title abstract 3
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 108091034117 Oligonucleotide Proteins 0.000 title 1
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 title 1
- 239000007788 liquid Substances 0.000 abstract 9
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
- Y10T436/113332—Automated chemical analysis with conveyance of sample along a test line in a container or rack
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/2575—Volumetric liquid transfer
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Structural Engineering (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17031499P | 1999-12-13 | 1999-12-13 | |
| PCT/US2000/034127 WO2001041918A2 (en) | 1999-12-13 | 2000-12-13 | Oligonucleotide synthesizer using centrifugal force |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE527053T1 true ATE527053T1 (de) | 2011-10-15 |
Family
ID=22619389
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00988097T ATE527053T1 (de) | 1999-12-13 | 2000-12-13 | Syntheseeinrichtung für oligonukleotide unter nutzung von fliehkraft |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6663832B2 (de) |
| EP (1) | EP1239952B1 (de) |
| JP (1) | JP2004507337A (de) |
| AT (1) | ATE527053T1 (de) |
| AU (1) | AU779983B2 (de) |
| CA (1) | CA2394374A1 (de) |
| DK (1) | DK1239952T3 (de) |
| HK (1) | HK1049804B (de) |
| WO (1) | WO2001041918A2 (de) |
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-
2000
- 2000-12-13 CA CA002394374A patent/CA2394374A1/en not_active Abandoned
- 2000-12-13 AT AT00988097T patent/ATE527053T1/de not_active IP Right Cessation
- 2000-12-13 DK DK00988097.2T patent/DK1239952T3/da active
- 2000-12-13 EP EP00988097A patent/EP1239952B1/de not_active Expired - Lifetime
- 2000-12-13 US US09/738,473 patent/US6663832B2/en not_active Expired - Lifetime
- 2000-12-13 HK HK03101926.4A patent/HK1049804B/en not_active IP Right Cessation
- 2000-12-13 JP JP2001543254A patent/JP2004507337A/ja active Pending
- 2000-12-13 WO PCT/US2000/034127 patent/WO2001041918A2/en not_active Ceased
- 2000-12-13 AU AU24344/01A patent/AU779983B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DK1239952T3 (da) | 2012-01-02 |
| US20020028159A1 (en) | 2002-03-07 |
| US6663832B2 (en) | 2003-12-16 |
| CA2394374A1 (en) | 2001-06-14 |
| WO2001041918A3 (en) | 2002-01-17 |
| WO2001041918A2 (en) | 2001-06-14 |
| JP2004507337A (ja) | 2004-03-11 |
| AU2434401A (en) | 2001-06-18 |
| EP1239952B1 (de) | 2011-10-05 |
| EP1239952A2 (de) | 2002-09-18 |
| HK1049804B (en) | 2012-07-20 |
| AU779983B2 (en) | 2005-02-24 |
| HK1049804A1 (en) | 2003-05-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |