|
US3126375A
(en)
|
|
1964-03-24 |
|
Chioacyl |
|
US2789118A
(en)
|
1956-03-30 |
1957-04-16 |
American Cyanamid Co |
16-alpha oxy-belta1, 4-pregnadienes
|
|
US2990401A
(en)
|
1958-06-18 |
1961-06-27 |
American Cyanamid Co |
11-substituted 16alpha, 17alpha-substituted methylenedioxy steroids
|
|
US3048581A
(en)
|
1960-04-25 |
1962-08-07 |
Olin Mathieson |
Acetals and ketals of 16, 17-dihydroxy steroids
|
|
US3749712A
(en)
|
1970-09-25 |
1973-07-31 |
Sigma Tau Ind Farmaceuti |
Triamcinolone acetonide esters and process for their preparation
|
|
SE378109B
(de)
|
1972-05-19 |
1975-08-18 |
Bofors Ab |
|
|
US3996359A
(en)
|
1972-05-19 |
1976-12-07 |
Ab Bofors |
Novel stereoisomeric component A of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steroid 21-acylates, compositions thereof, and method of treating therewith
|
|
SE378110B
(de)
|
1972-05-19 |
1975-08-18 |
Bofors Ab |
|
|
US4231938A
(en)
|
1979-06-15 |
1980-11-04 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
|
US4294926A
(en)
|
1979-06-15 |
1981-10-13 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
|
US4319039A
(en)
|
1979-06-15 |
1982-03-09 |
Merck & Co., Inc. |
Preparation of ammonium salt of hypocholesteremic fermentation product
|
|
US4444784A
(en)
|
1980-08-05 |
1984-04-24 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
DK149080C
(da)
|
1980-06-06 |
1986-07-28 |
Sankyo Co |
Fremgangsmaade til fremstilling af derivater af ml-236b-carboxylsyre
|
|
JPS5889191A
(ja)
|
1981-11-20 |
1983-05-27 |
Sankyo Co Ltd |
３−ヒドロキシ−ｍｌ−２３６ｂ誘導体の製造法
|
|
US5354772A
(en)
|
1982-11-22 |
1994-10-11 |
Sandoz Pharm. Corp. |
Indole analogs of mevalonolactone and derivatives thereof
|
|
US4911165A
(en)
|
1983-01-12 |
1990-03-27 |
Ethicon, Inc. |
Pliabilized polypropylene surgical filaments
|
|
US4681893A
(en)
|
1986-05-30 |
1987-07-21 |
Warner-Lambert Company |
Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
|
|
US4782084A
(en)
|
1987-06-29 |
1988-11-01 |
Merck & Co., Inc. |
HMG-COA reductase inhibitors
|
|
US4885314A
(en)
|
1987-06-29 |
1989-12-05 |
Merck & Co., Inc. |
Novel HMG-CoA reductase inhibitors
|
|
US4820850A
(en)
|
1987-07-10 |
1989-04-11 |
Merck & Co., Inc. |
Process for α-C-alkylation of the 8-acyl group on mevinolin and analogs thereof
|
|
US5030447A
(en)
|
1988-03-31 |
1991-07-09 |
E. R. Squibb & Sons, Inc. |
Pharmaceutical compositions having good stability
|
|
US5180589A
(en)
|
1988-03-31 |
1993-01-19 |
E. R. Squibb & Sons, Inc. |
Pravastatin pharmaceuatical compositions having good stability
|
|
US4916239A
(en)
|
1988-07-19 |
1990-04-10 |
Merck & Co., Inc. |
Process for the lactonization of mevinic acids and analogs thereof
|
|
EP0360390A1
(de)
|
1988-07-25 |
1990-03-28 |
Glaxo Group Limited |
Spirolactamderivate
|
|
US5118853A
(en)
|
1988-10-13 |
1992-06-02 |
Sandoz Ltd. |
Processes for the synthesis of 3-disubstituted aminoacroleins
|
|
US5290946A
(en)
|
1988-10-13 |
1994-03-01 |
Sandoz Ltd. |
Processes for the synthesis of 3-(substituted indolyl-2-yl)propenaldehydes
|
|
MX18467A
(es)
|
1988-11-23 |
1993-07-01 |
Pfizer |
Agentes terapeuticos de quinuclidinas
|
|
US4929437A
(en)
|
1989-02-02 |
1990-05-29 |
Merck & Co., Inc. |
Coenzyme Q10 with HMG-CoA reductase inhibitors
|
|
US5164372A
(en)
|
1989-04-28 |
1992-11-17 |
Fujisawa Pharmaceutical Company, Ltd. |
Peptide compounds having substance p antagonism, processes for preparation thereof and pharmaceutical composition comprising the same
|
|
US5189164A
(en)
|
1989-05-22 |
1993-02-23 |
Sandoz Ltd. |
Processes for the synthesis of syn-(E)-3,5-dihydroxy-7-substituted hept-6-enoic and heptanoic acids and derivatives and intermediates thereof
|
|
FI94339C
(fi)
|
1989-07-21 |
1995-08-25 |
Warner Lambert Co |
Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
|
|
PH27357A
(en)
|
1989-09-22 |
1993-06-21 |
Fujisawa Pharmaceutical Co |
Pyrazole derivatives and pharmaceutical compositions comprising the same
|
|
IE903957A1
(en)
|
1989-11-06 |
1991-05-08 |
Sanofi Sa |
Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present
|
|
FR2654726B1
(fr)
|
1989-11-23 |
1992-02-14 |
Rhone Poulenc Sante |
Nouveaux derives de l'isoindolone et leur preparation.
|
|
FR2654725B1
(fr)
|
1989-11-23 |
1992-02-14 |
Rhone Poulenc Sante |
Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
GB8929070D0
(en)
|
1989-12-22 |
1990-02-28 |
Fujisawa Pharmaceutical Co |
Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
|
|
US5232929A
(en)
|
1990-11-28 |
1993-08-03 |
Pfizer Inc. |
3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
|
|
WO1991009844A1
(en)
|
1990-01-04 |
1991-07-11 |
Pfizer Inc. |
Substance p antagonists
|
|
EP0515681A4
(en)
|
1990-02-15 |
1993-12-29 |
Fujisawa Pharmaceutical Co., Ltd. |
Peptide compound
|
|
US5420245A
(en)
|
1990-04-18 |
1995-05-30 |
Board Of Regents, The University Of Texas |
Tetrapeptide-based inhibitors of farnesyl transferase
|
|
JPH072740B2
(ja)
|
1990-06-01 |
1995-01-18 |
フアイザー・インコーポレイテツド |
３―アミノ―２―アリールキヌクリジン
|
|
WO1992001688A1
(en)
|
1990-07-23 |
1992-02-06 |
Pfizer Inc. |
Quinuclidine derivatives
|
|
BR9106905A
(pt)
|
1990-09-28 |
1993-08-17 |
Pfizer |
Analogos de anel condensado de heterociclos nao aromaticos contendo nitrogenio
|
|
GB9023116D0
(en)
|
1990-10-24 |
1990-12-05 |
Fujisawa Pharmaceutical Co |
Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
|
|
US5177080A
(en)
|
1990-12-14 |
1993-01-05 |
Bayer Aktiengesellschaft |
Substituted pyridyl-dihydroxy-heptenoic acid and its salts
|
|
DK0498069T3
(da)
|
1990-12-21 |
1995-12-04 |
Fujisawa Pharmaceutical Co |
Ny anvendelse af peptidderivat
|
|
HUT65612A
(en)
|
1991-01-10 |
1994-07-28 |
Pfizer |
Process n-alcyl-quinuclidinium salts of p-antagonistic activity
|
|
EP0499313B1
(de)
|
1991-02-11 |
1997-06-11 |
MERCK SHARP & DOHME LTD. |
Azabicyclische Verbindungen, diese enthaltende pharmazeutische Zubereitungen und ihre therapeutische Verwendung
|
|
JPH082901B2
(ja)
|
1991-03-01 |
1996-01-17 |
ファイザー・インコーポレーテッド |
１−アザビシクロ［３．２．２ノナン−３−アミン誘導体類
|
|
US5747469A
(en)
|
1991-03-06 |
1998-05-05 |
Board Of Regents, The University Of Texas System |
Methods and compositions comprising DNA damaging agents and p53
|
|
CZ293955B6
(cs)
|
1991-03-26 |
2004-08-18 |
Pfizeráinc |
Postup přípravy substituovaných piperidinů
|
|
FR2677361A1
(fr)
|
1991-06-04 |
1992-12-11 |
Adir |
Nouveaux peptides et pseudopeptides, derives de tachykinines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
|
|
FR2676053B1
(fr)
|
1991-05-03 |
1993-08-27 |
Sanofi Elf |
Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
|
FR2676055B1
(fr)
|
1991-05-03 |
1993-09-03 |
Sanofi Elf |
Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
|
FR2676447B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives du thiopyranopyrrole et leur preparation.
|
|
FR2676446B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives du thiopyranopyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
FR2676442B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
FR2676443B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole et leur preparation.
|
|
CA2109415C
(en)
|
1991-05-22 |
1998-12-29 |
Fumitaka Ito |
Substituted 3-aminoquinuclidines
|
|
US5292726A
(en)
|
1991-05-22 |
1994-03-08 |
Merck & Co., Inc. |
N,N-diacylpiperazines
|
|
UA27776C2
(uk)
|
1991-05-31 |
2000-10-16 |
Пфайзер Інк. |
Похідні хінуклідину та їх фармацевтично прийнятні солі, що є антагоністами речовини р у ссавців, фармацевтична композиція, що має антагоністичну дію на речовину р у ссавців
|
|
GB9113219D0
(en)
|
1991-06-19 |
1991-08-07 |
Fujisawa Pharmaceutical Co |
Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same
|
|
AU657967B2
(en)
|
1991-06-20 |
1995-03-30 |
Pfizer Inc. |
Fluoroalkoxybenzylamino derivatives of nitrogen containing heterocycles
|
|
TW202432B
(de)
|
1991-06-21 |
1993-03-21 |
Pfizer |
|
|
US5288730A
(en)
|
1991-06-24 |
1994-02-22 |
Merck Sharp & Dohme Limited |
Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
|
EP0593559A1
(de)
|
1991-07-05 |
1994-04-27 |
MERCK SHARP & DOHME LTD. |
Aromatische verbindungen, diese enthaltende arzneimittel und ihre therapeutische verwendung
|
|
JPH06509332A
(ja)
|
1991-07-05 |
1994-10-20 |
メルク シヤープ エンド ドーム リミテツド |
芳香族化合物、それらを含む医薬組成物、及び治療におけるそれらの使用
|
|
EP0536817A1
(de)
|
1991-07-05 |
1993-04-14 |
MERCK SHARP & DOHME LTD. |
Azabicyclische Verbindungen als Tachykinin-Antagonisten
|
|
DE69208089T2
(de)
|
1991-07-10 |
1996-08-22 |
Merck Sharp & Dohme |
Aromatische verbindungen diese enthaltende pharmazeutische zusammensetzungen und ihre therapeutische verwendung
|
|
WO1993001159A1
(en)
|
1991-07-10 |
1993-01-21 |
Merck Sharp & Dohme Limited |
Fused tricyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
|
MY110227A
(en)
|
1991-08-12 |
1998-03-31 |
Ciba Geigy Ag |
1-acylpiperindine compounds.
|
|
JPH06510034A
(ja)
|
1991-08-20 |
1994-11-10 |
メルク シヤープ エンド ドーム リミテツド |
アザ環式化合物、それらの製造方法、及びそれらを含む医薬組成物
|
|
EP0919245A3
(de)
|
1991-09-20 |
2000-11-15 |
Glaxo Group Limited |
NK-1 Rezeptor Antagonist mit einem systemischen antiinflammatorischen Kortikosteroid zur Behandlung von Emesis
|
|
ATE216996T1
(de)
|
1991-09-26 |
2002-05-15 |
Pfizer |
Kondensierte trizyklische, stickstoffenthaltende verbindungen als substanz p rezeptor antagonisten
|
|
WO1993009116A1
(fr)
|
1991-11-07 |
1993-05-13 |
Yoshitomi Pharmaceutical Industries, Ltd. |
Compose a base de quinuclidine et utilisation dudit compose en medecine
|
|
DK0613458T3
(da)
|
1991-11-12 |
1998-02-09 |
Pfizer |
Acykliske ethylendiaminderivater som substans P receptorantagonister
|
|
CA2083891A1
(en)
|
1991-12-03 |
1993-06-04 |
Angus Murray Macleod |
Heterocyclic compounds, compositions containing them and their use in therapy
|
|
HU9203780D0
(en)
|
1991-12-12 |
1993-03-29 |
Sandoz Ag |
Stabilized pharmaceutical products of hmg-coa reductase inhibitor and method for producing them
|
|
GB9200535D0
(en)
|
1992-01-10 |
1992-02-26 |
Fujisawa Pharmaceutical Co |
New compound
|
|
GB9201179D0
(en)
|
1992-01-21 |
1992-03-11 |
Glaxo Group Ltd |
Chemical compounds
|
|
US5328927A
(en)
|
1992-03-03 |
1994-07-12 |
Merck Sharpe & Dohme, Ltd. |
Hetercyclic compounds, processes for their preparation and pharmaceutical compositions containing them
|
|
JP2656702B2
(ja)
|
1992-03-23 |
1997-09-24 |
ファイザー製薬株式会社 |
ペプチド性キヌクリジン
|
|
FR2689888B1
(fr)
|
1992-04-10 |
1994-06-10 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
|
JPH07505648A
(ja)
|
1992-04-15 |
1995-06-22 |
メルク シヤープ エンド ドーム リミテツド |
アザサイクリック化合物
|
|
GB2266529A
(en)
|
1992-05-01 |
1993-11-03 |
Merck Sharp & Dohme |
Tetrahydroisoquinoline derivatives
|
|
EP0641328B1
(de)
|
1992-05-18 |
2001-11-21 |
Pfizer Inc. |
Überbrückte azabicyclische derivate als substanz p antagonisten
|
|
GB9211193D0
(en)
|
1992-05-27 |
1992-07-08 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5637699A
(en)
|
1992-06-29 |
1997-06-10 |
Merck & Co., Inc. |
Process for preparing morpholine tachykinin receptor antagonists
|
|
US5719147A
(en)
|
1992-06-29 |
1998-02-17 |
Merck & Co., Inc. |
Morpholine and thiomorpholine tachykinin receptor antagonists
|
|
CA2099233A1
(en)
|
1992-06-29 |
1993-12-30 |
Conrad P. Dorn |
Morpholine and thiomorpholine tachykinin receptor antagonists
|
|
WO1994001402A1
(en)
|
1992-07-13 |
1994-01-20 |
Merck Sharp & Dohme Limited |
Heterocyclic amide derivatives as tachykinin derivatives
|
|
JPH07509133A
(ja)
|
1992-07-17 |
1995-10-12 |
リボザイム・ファーマシューティカルズ・インコーポレイテッド |
動物疾患の処置のための方法および剤
|
|
GB2268931A
(en)
|
1992-07-22 |
1994-01-26 |
Merck Sharp & Dohme |
Azabicyclic tachykinin-receptor antagonists
|
|
WO1994002461A1
(en)
|
1992-07-28 |
1994-02-03 |
Merck Sharp & Dohme Limited |
Azacyclic compounds
|
|
GB2269170A
(en)
|
1992-07-29 |
1994-02-02 |
Merck Sharp & Dohme |
Azatricyclic tachykinin antagonists
|
|
WO1994003429A1
(en)
|
1992-07-31 |
1994-02-17 |
Merck Sharp & Dohme Limited |
Substituted amines as tachykinin receptor antagonists
|
|
AU4396193A
(en)
|
1992-08-04 |
1994-03-03 |
Pfizer Inc. |
3-benzylamino-2-phenyl-piperidine derivatives as substance p receptor antagonists
|
|
GB9216911D0
(en)
|
1992-08-10 |
1992-09-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
JP3507494B2
(ja)
|
1992-08-13 |
2004-03-15 |
ワーナー−ランバート・コンパニー |
タキキニン拮抗薬
|
|
JP2909214B2
(ja)
|
1992-08-19 |
1999-06-23 |
フアイザー・インコーポレイテツド |
置換ベンジルアミノ窒素含有非芳香族複素環化合物
|
|
US5387595A
(en)
|
1992-08-26 |
1995-02-07 |
Merck & Co., Inc. |
Alicyclic compounds as tachykinin receptor antagonists
|
|
EP0585913B1
(de)
|
1992-09-04 |
1997-12-29 |
Takeda Chemical Industries, Ltd. |
Kondensierte heterozyklische Verbindungen, deren Herstellung und Verwendung
|
|
US5563161A
(en)
|
1992-09-10 |
1996-10-08 |
Merck Sharp & Dohme Ltd. |
Alcohols and ethers with aromatic substituents as tachykinin-antagonists
|
|
GB9220286D0
(en)
|
1992-09-25 |
1992-11-11 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
JP2656699B2
(ja)
|
1992-10-21 |
1997-09-24 |
ファイザー製薬株式会社 |
置換ベンジルアミノキヌクリジン
|
|
GB9222262D0
(en)
|
1992-10-23 |
1992-12-09 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9222486D0
(en)
|
1992-10-26 |
1992-12-09 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
JP2656700B2
(ja)
|
1992-10-28 |
1997-09-24 |
ファイザー製薬株式会社 |
置換キヌクリジン誘導体
|
|
EP0666856B1
(de)
|
1992-10-28 |
2000-01-05 |
MERCK SHARP & DOHME LTD. |
4-arylmethyloxymethyl piperidine als tachykinin antagonisten
|
|
US5554627A
(en)
|
1992-10-30 |
1996-09-10 |
Merck, Sharp & Dohme Ltd. |
Tachykinin antagonists
|
|
KR950704311A
(ko)
|
1992-11-12 |
1995-11-17 |
알렌 제이. 스피겔 |
물질 p 길항체로서의 퀴누클리딘 유도체(quinuclidine derivative as substance p antagonist)
|
|
US5261188A
(en)
|
1992-11-23 |
1993-11-16 |
The Standard Products Company |
Belt weatherstrip with bulb
|
|
JP2722279B2
(ja)
|
1992-12-10 |
1998-03-04 |
ファイザー・インク． |
アミノメチレンで置換した非芳香族複素環式化合物及びサブスタンスｐのアンタゴニストとしての使用
|
|
US5604260A
(en)
|
1992-12-11 |
1997-02-18 |
Merck Frosst Canada Inc. |
5-methanesulfonamido-1-indanones as an inhibitor of cyclooxygenase-2
|
|
CA2150951A1
(en)
|
1992-12-14 |
1994-06-23 |
Angus Murray Macleod |
4-aminomethyl/thiomethyl/sulfonylmethyl-4-phenylpiperidines as tachykinin receptor antagonists
|
|
CA2111902A1
(en)
|
1992-12-21 |
1994-06-22 |
Jack Beuford Campbell |
Antitumor compositions and methods of treatment
|
|
GB9226581D0
(en)
|
1992-12-21 |
1993-02-17 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9300051D0
(en)
|
1993-01-04 |
1993-03-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
CA2293952A1
(en)
|
1993-01-15 |
1994-07-21 |
David B. Reitz |
Preparation of esters and analogs thereof
|
|
EP0610793A1
(de)
|
1993-02-08 |
1994-08-17 |
Takeda Chemical Industries, Ltd. |
Tetracyclische Morpholin-Derivate und ihre Verwendung als Analgetika
|
|
ATE166867T1
(de)
|
1993-02-18 |
1998-06-15 |
Merck Sharp & Dohme |
Azacyclische verbindungen, sie enthaltende zusammensetzungen und ihre verwendung als tachykinin antagoniste
|
|
US5674889A
(en)
|
1993-02-22 |
1997-10-07 |
Merck, Sharp & Dohme, Ltd. |
Aromatic compounds, compositions containing them and their use in therapy
|
|
WO1994019357A1
(en)
|
1993-02-23 |
1994-09-01 |
Merrell Dow Pharmaceuticals Inc. |
Farnesyl:protein transferase inhibitors as anticancer agents
|
|
US5298627A
(en)
|
1993-03-03 |
1994-03-29 |
Warner-Lambert Company |
Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
|
|
WO1994020500A1
(en)
|
1993-03-04 |
1994-09-15 |
Pfizer Inc. |
Spiroazacyclic derivatives as substance p antagonists
|
|
US5409944A
(en)
|
1993-03-12 |
1995-04-25 |
Merck Frosst Canada, Inc. |
Alkanesulfonamido-1-indanone derivatives as inhibitors of cyclooxygenase
|
|
CA2118985A1
(en)
|
1993-04-02 |
1994-10-03 |
Dinesh V. Patel |
Heterocyclic inhibitors of farnesyl protein transferase
|
|
US5496833A
(en)
|
1993-04-13 |
1996-03-05 |
Merck Sharp & Dohme Limited |
Piperidine tachykinin receptor antagonists
|
|
NZ267209A
(en)
|
1993-05-06 |
1997-09-22 |
Merrell Dow Pharma |
Substituted pyrrolidin-3-yl-alkyl-piperidine derivatives, preparation and pharmaceutical compositions thereof
|
|
JPH09500615A
(ja)
|
1993-05-14 |
1997-01-21 |
ジェネンテク，インコーポレイテッド |
Ｒａｓ−ファルネシル転移酵素阻害剤
|
|
US5602098A
(en)
|
1993-05-18 |
1997-02-11 |
University Of Pittsburgh |
Inhibition of farnesyltransferase
|
|
IL109646A0
(en)
|
1993-05-19 |
1994-08-26 |
Pfizer |
Heteroatom substituted alkyl benzylamino-quinuclidines
|
|
US5380738A
(en)
|
1993-05-21 |
1995-01-10 |
Monsanto Company |
2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents
|
|
CA2163995A1
(en)
|
1993-06-07 |
1994-12-22 |
Malcolm Maccoss |
Spiro-substituted azacycles as neurokinin antagonists
|
|
US5436265A
(en)
|
1993-11-12 |
1995-07-25 |
Merck Frosst Canada, Inc. |
1-aroyl-3-indolyl alkanoic acids and derivatives thereof useful as anti-inflammatory agents
|
|
US5474995A
(en)
|
1993-06-24 |
1995-12-12 |
Merck Frosst Canada, Inc. |
Phenyl heterocycles as cox-2 inhibitors
|
|
GB9602877D0
(en)
|
1996-02-13 |
1996-04-10 |
Merck Frosst Canada Inc |
3,4-Diaryl-2-hydroxy-2,5- dihydrofurans as prodrugs to cox-2 inhibitors
|
|
EP0634402A1
(de)
|
1993-07-14 |
1995-01-18 |
Takeda Chemical Industries, Ltd. |
Isochinolinon-Derivate, ihre Herstellung und Verwendung
|
|
CA2167198C
(en)
|
1993-07-15 |
1999-03-16 |
Kunio Satake |
Benzylaminoquinuclidines
|
|
GB9315808D0
(en)
|
1993-07-30 |
1993-09-15 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
TW365603B
(en)
|
1993-07-30 |
1999-08-01 |
Rhone Poulenc Rorer Sa |
Novel perhydroisoindole derivatives, their preparation and pharmaceutical compositions which contain them
|
|
GB9317987D0
(en)
|
1993-08-26 |
1993-10-13 |
Glaxo Group Ltd |
Chemical compounds
|
|
PT719253E
(pt)
|
1993-09-17 |
2004-07-30 |
Pfizer |
Piperidinas 3-amino-5-carboxi-substituidas e pirrolidinas 3-amino-4-carboxi-substituidas como antagonistas de taquicinina
|
|
EP0719266A1
(de)
|
1993-09-17 |
1996-07-03 |
Pfizer Inc. |
Durch heteroarylamino und heteroarylsulfonamido substituierte 3-benzylaminomethyl piperidine und verwandte derivate
|
|
IS4208A
(is)
|
1993-09-22 |
1995-03-23 |
Glaxo Group Limited |
3-(tetrazólýl-benzyl)amínó-piperadidín afleiður
|
|
EP0670314A4
(de)
|
1993-09-22 |
1996-04-10 |
Kyowa Hakko Kogyo Kk |
Farnesyltransferase inhibitoren.
|
|
ATE210652T1
(de)
|
1993-10-15 |
2001-12-15 |
Schering Corp |
Tricyclische carbamat-derivate zur inhibierung der g-protein funktion und für die behandlung von proliferativen erkrankungen
|
|
US5661152A
(en)
|
1993-10-15 |
1997-08-26 |
Schering Corporation |
Tricyclic sulfonamide compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
|
ZA947969B
(en)
|
1993-10-15 |
1996-07-12 |
Schering Corp |
Tricyclic sulfonamide compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
|
|
IL111235A
(en)
|
1993-10-15 |
2001-03-19 |
Schering Plough Corp |
Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them
|
|
US5721236A
(en)
|
1993-10-15 |
1998-02-24 |
Schering Corporation |
Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
|
US5719148A
(en)
|
1993-10-15 |
1998-02-17 |
Schering Corporation |
Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
|
|
ES2157994T3
(es)
|
1993-10-25 |
2001-09-01 |
Parke Davis & Co |
Inhibidores tetra y pentapeptidos sustituidos de la proteina farnesiltransferasa.
|
|
WO1995011880A1
(en)
|
1993-10-27 |
1995-05-04 |
Merck Sharp & Dohme Limited |
Substituted amides as tachykinin antagonists
|
|
US5344991A
(en)
|
1993-10-29 |
1994-09-06 |
G.D. Searle & Co. |
1,2 diarylcyclopentenyl compounds for the treatment of inflammation
|
|
US5783593A
(en)
|
1993-11-04 |
1998-07-21 |
Abbott Laboratories |
Inhibitors of squalene synthetase and protein farnesyltransferase
|
|
DK0677039T3
(da)
|
1993-11-04 |
1999-09-27 |
Abbott Lab |
Cyclobutanderivater som squalen-syntetase- og protein-farnesyltransferaseinhibitorer
|
|
KR100362338B1
(ko)
|
1993-11-05 |
2003-04-08 |
워너-램버트 캄파니 |
단백질:파르네실트랜스퍼라아제의치환디-및트리펩티드억제제
|
|
US6403577B1
(en)
|
1993-11-17 |
2002-06-11 |
Eli Lilly And Company |
Hexamethyleneiminyl tachykinin receptor antagonists
|
|
US5466823A
(en)
|
1993-11-30 |
1995-11-14 |
G.D. Searle & Co. |
Substituted pyrazolyl benzenesulfonamides
|
|
IT1271462B
(it)
|
1993-12-03 |
1997-05-28 |
Menarini Farma Ind |
Antagonisti delle tachichinine,procedimento per la loro preparazione e loro impiego in formulazioni farmaceutiche.
|
|
US5484799A
(en)
|
1993-12-09 |
1996-01-16 |
Abbott Laboratories |
Antifungal dorrigocin derivatives
|
|
IL111960A
(en)
|
1993-12-17 |
1999-12-22 |
Merck & Co Inc |
Morpholines and thiomorpholines their preparation and pharmaceutical compositions containing them
|
|
JPH09506898A
(ja)
|
1993-12-21 |
1997-07-08 |
イーライ・リリー・アンド・カンパニー |
非ペプチドタキキニン受容体アンタゴニスト
|
|
WO1995018124A1
(en)
|
1993-12-29 |
1995-07-06 |
Merck Sharp & Dohme Limited |
Substituted morpholine derivatives and their use as therapeutic agents
|
|
WO1995018129A1
(en)
|
1993-12-29 |
1995-07-06 |
Pfizer Inc. |
Diazabicyclic neurokinin antagonists
|
|
ES2120170T3
(es)
|
1994-01-13 |
1998-10-16 |
Merck Sharp & Dohme |
Antagonistas azaciclicos gem-disustituidos de taquiquininas.
|
|
US5728716A
(en)
|
1994-01-28 |
1998-03-17 |
Merck Sharp & Dohme Limited |
Aralkylamino substituted azacyclic therapeutic agents
|
|
US5393790A
(en)
|
1994-02-10 |
1995-02-28 |
G.D. Searle & Co. |
Substituted spiro compounds for the treatment of inflammation
|
|
GB9402688D0
(en)
|
1994-02-11 |
1994-04-06 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5610165A
(en)
|
1994-02-17 |
1997-03-11 |
Merck & Co., Inc. |
N-acylpiperidine tachykinin antagonists
|
|
IL112778A0
(en)
|
1994-03-04 |
1995-05-26 |
Merck & Co Inc |
Substituted heterocycles, their preparation and pharmaceutical compositions containing them
|
|
WO1995024612A1
(de)
|
1994-03-07 |
1995-09-14 |
International Business Machines Corporation |
Verfahren und vorrichtung zur schnellen interpolation von zwischenwerten aus periodischen phasenverschobenen signalen und zur erkennung von defekten in einem drehkörper
|
|
HUT77406A
(hu)
|
1994-03-15 |
1998-04-28 |
Eisai Co., Ltd., |
1-(4-Amino-5-tio-pent-2-en)-il oldalláncot tartalmazó peptidomimetikumok és az ezeket tartalmazó gyógyszerkészítmények
|
|
FR2718136B1
(fr)
|
1994-03-29 |
1996-06-21 |
Sanofi Sa |
Composés aromatiques aminés, procédé pour leur obtention et compositions pharmaceutiques les contenant.
|
|
RU95104898A
(ru)
|
1994-03-31 |
1996-12-27 |
Бристоль-Мейерз Сквибб Компани (US) |
Имидазолсодержащие ингибиторы фарнезид-протеинтрансферазы, способ лечения связанных с ней заболеваний
|
|
US5523430A
(en)
|
1994-04-14 |
1996-06-04 |
Bristol-Myers Squibb Company |
Protein farnesyl transferase inhibitors
|
|
US5610145A
(en)
|
1994-04-15 |
1997-03-11 |
Warner-Lambert Company |
Tachykinin antagonists
|
|
IL113472A0
(en)
|
1994-04-29 |
1995-07-31 |
Lilly Co Eli |
Non-peptidyl tachykinin receptor antogonists
|
|
WO1995030674A1
(en)
|
1994-05-05 |
1995-11-16 |
Merck Sharp & Dohme Limited |
Morpholine derivatives and their use as antagonists of tachikinins
|
|
JPH09512806A
(ja)
|
1994-05-07 |
1997-12-22 |
ベーリンガー インゲルハイム コマンディトゲゼルシャフト |
新規なアミノ酸誘導体、その製造方法及びこれらの化合物を含む医薬組成物（ｉｉ）
|
|
US5510510A
(en)
|
1994-05-10 |
1996-04-23 |
Bristol-Meyers Squibb Company |
Inhibitors of farnesyl protein transferase
|
|
US5563255A
(en)
|
1994-05-31 |
1996-10-08 |
Isis Pharmaceuticals, Inc. |
Antisense oligonucleotide modulation of raf gene expression
|
|
JPH10501228A
(ja)
|
1994-06-06 |
1998-02-03 |
ワーナー−ランバート・コンパニー |
タキキニン（ｎｋ▲下１▼）受容体アンタゴニスト
|
|
EP0686629A3
(de)
|
1994-06-10 |
1999-02-10 |
Eli Lilly And Company |
Cyclohexyl-Antagonisten von Tachykininrezeptoren
|
|
AU2742195A
(en)
|
1994-06-10 |
1996-01-05 |
Rhone-Poulenc Rorer S.A. |
Novel farnesyl transferase inhibitors, their preparation and pharmaceutical compositions containing same
|
|
US5571792A
(en)
|
1994-06-30 |
1996-11-05 |
Warner-Lambert Company |
Histidine and homohistidine derivatives as inhibitors of protein farnesyltransferase
|
|
CA2194471C
(en)
|
1994-07-12 |
2005-04-12 |
Sung-Yong Stephen Cho |
Bis-piperidinyl non-peptidyl tachykinin receptor antagonist
|
|
CA2154116A1
(en)
|
1994-07-22 |
1996-01-23 |
Philip Arthur Hipskind |
1-aryl-2-acetamidopentanone derivatives for use as tachykinin receptor antagonists
|
|
GB9415997D0
(en)
|
1994-08-08 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9415996D0
(en)
|
1994-08-08 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
TW432061B
(en)
|
1994-08-09 |
2001-05-01 |
Pfizer Res & Dev |
Lactams
|
|
WO1996005529A1
(en)
|
1994-08-09 |
1996-02-22 |
Micron Optics, Inc. |
Temperature compensated fiber fabry-perot filters
|
|
CA2155448A1
(en)
|
1994-08-11 |
1996-02-12 |
Katerina Leftheris |
Inhibitors of farnesyl protein transferase
|
|
AU3192395A
(en)
|
1994-08-11 |
1996-03-07 |
Banyu Pharmaceutical Co., Ltd. |
Substituted amide derivative
|
|
WO1996005169A1
(en)
|
1994-08-12 |
1996-02-22 |
Banyu Pharmaceutical Co., Ltd. |
N,n-disubstituted amic acid derivative
|
|
US5824678A
(en)
|
1994-08-15 |
1998-10-20 |
Merck Sharp & Dohme Ltd. |
Morpholine derivatives and their use as therapeutic agents
|
|
DE4429506B4
(de)
|
1994-08-19 |
2007-09-13 |
Degussa Gmbh |
Verfahren zur Extraktion natürlicher Carotinoid-Farbstoffe
|
|
DE4429653C2
(de)
|
1994-08-20 |
1997-04-03 |
Anton Dr More |
Konverter und Verfahren zum Frischen von Metallschmelzen insbesondere von Roheisen zu Stahl
|
|
CN1067385C
(zh)
|
1994-08-25 |
2001-06-20 |
默里尔药物公司 |
用于治疗变应性疾病的新的取代的哌啶类化合物
|
|
ATE158568T1
(de)
|
1994-08-29 |
1997-10-15 |
Akzo Nobel Nv |
Verfahren zur herstellung von quaternären diestern
|
|
GB9417956D0
(en)
|
1994-09-02 |
1994-10-26 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9418545D0
(en)
|
1994-09-15 |
1994-11-02 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5457107A
(en)
|
1994-09-16 |
1995-10-10 |
Merck & Co., Inc. |
Polymorphic form of a tachykinin receptor antagonist
|
|
JPH10506399A
(ja)
|
1994-09-30 |
1998-06-23 |
ノバルティス アクチェンゲゼルシャフト |
１−アシル−４−マリファチルアミノピペリジン化合物
|
|
TW397825B
(en)
|
1994-10-14 |
2000-07-11 |
Novartis Ag |
Aroyl-piperidine derivatives
|
|
FR2725986B1
(fr)
|
1994-10-21 |
1996-11-29 |
Adir |
Nouveaux derives de piperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
|
DE69534213T2
(de)
|
1994-10-25 |
2006-01-12 |
Astrazeneca Ab |
Therapeutisch wirksame Heterocyclen
|
|
GB9421709D0
(en)
|
1994-10-27 |
1994-12-14 |
Zeneca Ltd |
Therapeutic compounds
|
|
JP4319251B2
(ja)
|
1994-11-22 |
2009-08-26 |
エヌエックスピー ビー ヴィ |
半導体素子を有し導体トラックが形成されている基板が接着層により結合されている支持本体を有する半導体装置
|
|
CA2162786A1
(en)
|
1994-11-22 |
1996-05-23 |
Philip Arthur Hipskind |
Heterocyclic tachykinin receptor antagonists
|
|
FR2727411B1
(fr)
|
1994-11-30 |
1997-01-03 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
WO1996017861A1
(en)
|
1994-12-09 |
1996-06-13 |
Warner-Lambert Company |
Substituted tetra- and pentapeptide inhibitors of protein:farnesyl transferase
|
|
IL116323A0
(en)
|
1994-12-13 |
1996-03-31 |
Sandoz Ag |
Tachykinin antagonists their preparation and pharmaceutical compositions containing them
|
|
GB9426103D0
(en)
|
1994-12-23 |
1995-02-22 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
EA000164B1
(ru)
|
1995-01-09 |
1998-10-29 |
Магла Интернэшнл Лтд. |
Состав для печати изображения на поверхности изделия из каучукового латекса, способ печати изображения и изделия из каучукового латекса
|
|
EP0802912B1
(de)
|
1995-01-12 |
2004-10-13 |
Glaxo Group Limited |
Piperidinderivate mit tachykinin-antagonistischer wirkung
|
|
JP3929069B2
(ja)
|
1995-01-12 |
2007-06-13 |
ユニバーシティ オブ ピッツバーグ |
プレニルトランスフェラーゼの阻害剤
|
|
FR2729390A1
(fr)
|
1995-01-18 |
1996-07-19 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
FR2729951B1
(fr)
|
1995-01-30 |
1997-04-18 |
Sanofi Sa |
Nouveaux composes heterocycliques, procede pour leur preparation et compositions pharmaceutiques en contenant
|
|
FR2730491B1
(fr)
|
1995-02-09 |
1997-03-14 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
FR2730492B1
(fr)
|
1995-02-09 |
1997-03-14 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
US5633272A
(en)
|
1995-02-13 |
1997-05-27 |
Talley; John J. |
Substituted isoxazoles for the treatment of inflammation
|
|
GB9505491D0
(en)
|
1995-03-18 |
1995-05-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9505492D0
(en)
|
1995-03-18 |
1995-05-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US5554641A
(en)
|
1995-03-20 |
1996-09-10 |
Horwell; David C. |
Nonpeptides as tachykinin antagonists
|
|
GB9505692D0
(en)
|
1995-03-21 |
1995-05-10 |
Glaxo Group Ltd |
Chemical compounds
|
|
US5700806A
(en)
|
1995-03-24 |
1997-12-23 |
Schering Corporation |
Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
|
EP0733632B1
(de)
|
1995-03-24 |
2003-06-04 |
Takeda Chemical Industries, Ltd. |
Zyklische Verbindungen, ihre Herstellung und ihre Verwendung als Tachykininrezeptorantagonisten
|
|
US5684013A
(en)
|
1995-03-24 |
1997-11-04 |
Schering Corporation |
Tricyclic compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
|
|
IL117580A0
(en)
|
1995-03-29 |
1996-07-23 |
Merck & Co Inc |
Inhibitors of farnesyl-protein transferase and pharmaceutical compositions containing them
|
|
US5565568A
(en)
|
1995-04-06 |
1996-10-15 |
Eli Lilly And Company |
2-acylaminopropanamides as tachykinin receptor antagonists
|
|
AU5432696A
(en)
|
1995-04-07 |
1996-10-23 |
Pharmacopeia, Inc. |
Carbonyl-piperazinyl and piperidinil compounds which inhibit farnesyl protein transferase
|
|
US5891872A
(en)
|
1995-04-07 |
1999-04-06 |
Schering Corporation |
Tricyclic compounds
|
|
US5712280A
(en)
|
1995-04-07 |
1998-01-27 |
Schering Corporation |
Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
|
IL117798A
(en)
|
1995-04-07 |
2001-11-25 |
Schering Plough Corp |
Tricyclic compounds useful for inhibiting the function of protein - G and for the treatment of malignant diseases, and pharmaceutical preparations containing them
|
|
KR100414321B1
(ko)
|
1995-04-13 |
2004-02-18 |
아벤티스 파마슈티칼스 인크. |
타치키닌수용체길항활성을갖는신규한치환된피페라진유도체
|
|
US5831115A
(en)
|
1995-04-21 |
1998-11-03 |
Abbott Laboratories |
Inhibitors of squalene synthase and protein farnesyltransferase
|
|
IL118101A0
(en)
|
1995-05-03 |
1996-09-12 |
Abbott Lab |
Inhibitors of farnesyltransferase
|
|
AU706021B2
(en)
|
1995-05-25 |
1999-06-03 |
Fujisawa Pharmaceutical Co., Ltd. |
Piperazine derivatives
|
|
WO1997000252A1
(en)
|
1995-06-16 |
1997-01-03 |
Warner-Lambert Company |
Tricyclic inhibitors of protein farnesyltransferase
|
|
GB9513118D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9513117D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB9513121D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
DE69612003T2
(de)
|
1995-07-07 |
2001-06-21 |
Pfizer Inc., New York |
Substituierte benzolaktamverbindungen als substanz-p-antagonisten
|
|
FR2736641B1
(fr)
|
1995-07-10 |
1997-08-22 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
AT402617B
(de)
|
1995-07-11 |
1997-07-25 |
Datacon Schweitzer & Zeindl Gm |
Anlage zum automatisierten, hermetischen anlage zum automatisierten, hermetischen verschliessen von gehäusen verschliessen von gehäusen
|
|
FR2736638B1
(fr)
|
1995-07-12 |
1997-08-22 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
|
CH690163A5
(fr)
|
1995-07-28 |
2000-05-31 |
Symphar Sa |
Dérivés gem-diphosphonates substitués utiles en tant qu'agents anti-cancers.
|
|
TW340842B
(en)
|
1995-08-24 |
1998-09-21 |
Pfizer |
Substituted benzylaminopiperidine compounds
|
|
US6020343A
(en)
|
1995-10-13 |
2000-02-01 |
Merck Frosst Canada, Inc. |
(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors
|
|
AU722883B2
(en)
|
1995-10-18 |
2000-08-10 |
Merck & Co., Inc. |
Cyclopentyl tachykinin receptor antagonists
|
|
DE19541283A1
(de)
|
1995-11-06 |
1997-05-07 |
Boehringer Ingelheim Kg |
Neue Aminosäurederivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
|
|
WO1997017070A1
(en)
|
1995-11-06 |
1997-05-15 |
University Of Pittsburgh |
Inhibitors of protein isoprenyl transferases
|
|
GB9523244D0
(en)
|
1995-11-14 |
1996-01-17 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
EP1186606B2
(de)
|
1995-11-17 |
2011-09-07 |
Gesellschaft für Biotechnologische Forschung mbH (GBF) |
Epothilon-Derivate, ihre Herstellung und Verwendung
|
|
EP0862435A4
(de)
|
1995-11-22 |
1999-02-03 |
Merck & Co Inc |
Inhibitoren der farnesyl-protein-transferase
|
|
US6060469A
(en)
|
1995-11-23 |
2000-05-09 |
Merck Sharp & Dohme Ltd. |
Spiro-piperidine derivatives and their use as tachykinin antagonists
|
|
GB9524157D0
(en)
|
1995-11-25 |
1996-01-24 |
Pfizer Ltd |
Therapeutic agents
|
|
RU2135494C1
(ru)
|
1995-12-01 |
1999-08-27 |
Санкио Компани Лимитед |
Гетероциклические соединения и композиция на их основе, проявляющая антагонистическое действие в отношении рецепторов тахикинина
|
|
SI0865440T1
(en)
|
1995-12-08 |
2002-08-31 |
Janssen Pharmaceutica N.V. |
Farnesyl protein transferase inhibiting (imidazol-5-yl)methyl-2-quinolinone derivatives
|
|
GB9525296D0
(en)
|
1995-12-11 |
1996-02-07 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
CA2240846C
(en)
|
1995-12-22 |
2002-07-16 |
Schering Corporation |
Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases
|
|
AU1529997A
(en)
|
1996-01-16 |
1997-08-11 |
Warner-Lambert Company |
Substituted histidine inhibitors of protein farnesyltransferase
|
|
US6673927B2
(en)
|
1996-02-16 |
2004-01-06 |
Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. |
Farnesyl transferase inhibitors
|
|
EP0944388A4
(de)
|
1996-04-03 |
2001-08-16 |
Merck & Co Inc |
Hemmern von farnesyl protein transferase
|
|
ATE233743T1
(de)
|
1996-04-12 |
2003-03-15 |
Searle & Co |
N-((4-(5-methyl-3-phenylisoxazol-4- yl)phenyl)sulphonylpropylamid und sein natriumsalz als pro-pharmakon von cox-2 inhibitoren
|
|
BR9709354A
(pt)
|
1996-05-22 |
1999-08-10 |
Warner Lambert Co |
Inibidores de proteína farnesil transferase
|
|
AU709409B2
(en)
|
1996-07-15 |
1999-08-26 |
Bristol-Myers Squibb Company |
Thiadioxobenzodiazepine inhibitors of farnesyl protein transferase
|
|
US5861419A
(en)
|
1996-07-18 |
1999-01-19 |
Merck Frosst Canad, Inc. |
Substituted pyridines as selective cyclooxygenase-2 inhibitors
|
|
CA2273083C
(en)
|
1996-12-03 |
2012-09-18 |
Sloan-Kettering Institute For Cancer Research |
Synthesis of epothilones, intermediates thereto, analogues and uses thereof
|
|
JP2001507699A
(ja)
|
1996-12-30 |
2001-06-12 |
メルク エンド カンパニー インコーポレーテッド |
ファルネシル蛋白トランスフェラーゼ阻害薬
|
|
EP1003374A4
(de)
|
1996-12-30 |
2000-05-31 |
Merck & Co Inc |
Inhibitoren von farnesyl-protein-transferase
|
|
WO2000044777A1
(en)
|
1999-01-29 |
2000-08-03 |
Imclone Systems Incorporated |
Antibodies specific to kdr and uses thereof
|
|
GB9904387D0
(en)
|
1999-02-25 |
1999-04-21 |
Pharmacia & Upjohn Spa |
Antitumour synergistic composition
|
|
WO2000061186A1
(en)
|
1999-04-08 |
2000-10-19 |
Arch Development Corporation |
Use of anti-vegf antibody to enhance radiation in cancer therapy
|
|
CA2400021A1
(en)
|
2000-02-18 |
2001-08-23 |
Merck & Co., Inc. |
Aryloxyacetic acids for diabetes and lipid disorders
|
|
CA2404125C
(en)
|
2000-03-20 |
2011-01-25 |
Merck Sharp & Dohme Limited |
Sulphonamido-substituted bridged bicycloalkyl derivatives
|
|
GB0012671D0
(en)
|
2000-05-24 |
2000-07-19 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
AU2001288628A1
(en)
|
2000-08-31 |
2002-03-13 |
Loyola University Chicago |
Method and reagents for treatment of skin disorders by modulating the notch pathway
|
|
AU9287401A
(en)
|
2000-09-27 |
2002-04-08 |
Merck & Co Inc |
Benzopyrancarboxylic acid derivatives for the treatment of diabetes and lipid disorders
|
|
GB0025173D0
(en)
|
2000-10-13 |
2000-11-29 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
CA2427206C
(en)
|
2000-11-02 |
2011-06-28 |
Merck Sharp & Dohme Limited |
Sulfamides as gamma-secretase inhibitors
|
|
UA74849C2
(en)
|
2000-11-17 |
2006-02-15 |
Lilly Co Eli |
Lactam
|
|
GB0108591D0
(en)
|
2001-04-05 |
2001-05-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB0108592D0
(en)
|
2001-04-05 |
2001-05-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
US6958334B2
(en)
|
2001-04-10 |
2005-10-25 |
Merck & Co., Inc. |
Inhibitors of Akt activity
|
|
EP1379250A2
(de)
|
2001-04-10 |
2004-01-14 |
Merck & Co., Inc. |
Verfahren zur behandlung von krebs
|
|
WO2002083139A1
(en)
|
2001-04-10 |
2002-10-24 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
|
WO2002083675A2
(en)
|
2001-04-10 |
2002-10-24 |
Merck Sharp & Dohme Limited |
Inhibitors of akt activity
|
|
JP4361276B2
(ja)
|
2001-04-10 |
2009-11-11 |
メルク エンド カムパニー インコーポレーテッド |
Ａｋｔ活性の阻害物質
|
|
GB0119152D0
(en)
|
2001-08-06 |
2001-09-26 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
WO2003013526A1
(en)
|
2001-08-08 |
2003-02-20 |
Merck & Co. Inc. |
Anticoagulant compounds
|
|
WO2003018543A1
(en)
*
|
2001-08-21 |
2003-03-06 |
Merck Sharp & Dohme Limited |
Novel cyclohexyl sulphones
|
|
EP1444209A4
(de)
|
2001-11-07 |
2005-02-16 |
Merck & Co Inc |
Inhibitoren mitotischer kinesine
|
|
ES2291543T3
(es)
|
2001-12-06 |
2008-03-01 |
MERCK & CO., INC. |
Inhibicion de kinesina mitotica.
|
|
AU2002351183B2
(en)
|
2001-12-06 |
2008-05-08 |
Merck Sharp & Dohme Corp. |
Mitotic kinesin inhibitors
|
|
JP4391825B2
(ja)
|
2001-12-06 |
2009-12-24 |
メルク エンド カムパニー インコーポレーテッド |
有糸分裂キネシン阻害剤
|
|
WO2003050122A2
(en)
|
2001-12-06 |
2003-06-19 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
WO2003049527A2
(en)
|
2001-12-06 |
2003-06-19 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
CA2478068C
(en)
|
2002-03-08 |
2011-02-08 |
Merck & Co., Inc. |
Dihydropyrazole compounds useful for treating or preventing cancer
|
|
CA2480880C
(en)
|
2002-04-08 |
2011-03-22 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
|
EP1496896A4
(de)
|
2002-04-08 |
2007-10-31 |
Merck & Co Inc |
Akt-wirkungshemmer
|
|
AU2003226271B2
(en)
|
2002-04-08 |
2007-10-18 |
Merck Sharp & Dohme Corp. |
Fused quinoxaline derivatives as inhibitors of Akt activity
|
|
AU2003226250B2
(en)
|
2002-04-08 |
2007-08-16 |
Merck Sharp & Dohme Corp. |
Inhibitors of Akt activity
|
|
EP1496981A2
(de)
|
2002-04-08 |
2005-01-19 |
Merck & Co., Inc. |
Verfahren zur behandlung von krebs
|
|
GB0209991D0
(en)
|
2002-05-01 |
2002-06-12 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB0209997D0
(en)
|
2002-05-01 |
2002-06-12 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
ATE435219T1
(de)
|
2002-05-01 |
2009-07-15 |
Merck Sharp & Dohme |
Heteroaryl substituierte spirocyclische sulfamide zur hemmung von gamma sekretase
|
|
GB0209995D0
(en)
|
2002-05-01 |
2002-06-12 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
EP1509507A4
(de)
|
2002-05-23 |
2006-09-13 |
Merck & Co Inc |
Inhibitoren von mitotischem kinesin
|
|
EP1517904A4
(de)
|
2002-05-23 |
2007-02-21 |
Merck & Co Inc |
Inhibitoren von mitotischem kinesin
|
|
KR20050010515A
(ko)
|
2002-06-14 |
2005-01-27 |
머크 앤드 캄파니 인코포레이티드 |
유사분열 키네신 억제제
|
|
DE60312516T2
(de)
|
2002-06-14 |
2007-11-22 |
Merck & Co., Inc. |
Inhibitoren von mitotischem kinesin
|
|
AU2003263963A1
(en)
|
2002-08-01 |
2004-02-23 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of |
Method of treating inflammatory arthropathies with suppressors of cpg oligonucleotides
|
|
GB0218041D0
(en)
|
2002-08-02 |
2002-09-11 |
Merck Sharp & Dohme |
Chemical process
|
|
GB0223040D0
(en)
|
2002-10-04 |
2002-11-13 |
Merck Sharp & Dohme |
Therapeutic compounds
|
|
GB0223038D0
(en)
|
2002-10-04 |
2002-11-13 |
Merck Sharp & Dohme |
Therapeutic compounds
|
|
GB0223039D0
(en)
|
2002-10-04 |
2002-11-13 |
Merck Sharp & Dohme |
Therapeutic compounds
|
|
US7235580B2
(en)
|
2002-10-18 |
2007-06-26 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
AU2003284981B2
(en)
|
2002-10-30 |
2009-05-28 |
Merck Sharp & Dohme Corp. |
Inhibitors of Akt activity
|
|
US20040102360A1
(en)
|
2002-10-30 |
2004-05-27 |
Barnett Stanley F. |
Combination therapy
|
|
GB0225475D0
(en)
|
2002-11-01 |
2002-12-11 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
GB0225474D0
(en)
|
2002-11-01 |
2002-12-11 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
EP1585391A4
(de)
|
2002-12-06 |
2006-03-15 |
Pharmacia Corp |
Mitoneet-polypeptide aus mitochondrienmembranen, modulatoren davon und verfahren zu ihrer verwendung
|
|
CA2508956A1
(en)
|
2002-12-20 |
2004-07-15 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
AU2003297230B2
(en)
|
2002-12-20 |
2009-11-26 |
Merck Sharp & Dohme Corp. |
Mitotic kinesin inhibitors
|
|
EP1596878A4
(de)
*
|
2003-02-18 |
2008-05-28 |
Roskamp Res Llc |
Antiangiogene und antitumorale eigenschaften von beta- und gamma-secretasehemmern
|
|
US7135575B2
(en)
*
|
2003-03-03 |
2006-11-14 |
Array Biopharma, Inc. |
P38 inhibitors and methods of use thereof
|
|
GB0308318D0
(en)
|
2003-04-10 |
2003-05-14 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
EP1620095A4
(de)
|
2003-04-24 |
2009-04-01 |
Merck & Co Inc |
Hemmer der akt aktivität
|
|
DE602004023838D1
(de)
|
2003-04-24 |
2009-12-10 |
Merck & Co Inc |
Hemmer der akt aktivität
|
|
DE602004026047D1
(de)
|
2003-04-24 |
2010-04-29 |
Merck Sharp & Dohme |
Hemmer der akt aktivität
|
|
US7579355B2
(en)
|
2003-04-24 |
2009-08-25 |
Merck & Co., Inc. |
Inhibitors of Akt activity
|
|
DE602004011767T2
(de)
|
2003-05-16 |
2009-02-19 |
Merck Sharp & Dohme Ltd., Hoddesdon |
Cyclohexylsulfone als gamma-sekretase-inhibitoren
|
|
CA2475186C
(en)
|
2003-07-17 |
2010-01-05 |
At&T Corp. |
Method and apparatus for windowing in entropy encoding
|
|
GB0318447D0
(en)
|
2003-08-05 |
2003-09-10 |
Merck Sharp & Dohme |
Therapeutic agents
|
|
KR100536215B1
(ko)
|
2003-08-05 |
2005-12-12 |
삼성에스디아이 주식회사 |
플라즈마 디스플레이 패널
|
|
CN100548296C
(zh)
|
2003-08-13 |
2009-10-14 |
默克公司 |
有丝分裂驱动蛋白抑制剂
|
|
PL1664026T3
(pl)
|
2003-08-15 |
2009-06-30 |
Merck Sharp & Dohme |
Inhibitory kinezyny mitotycznej
|
|
WO2005018547A2
(en)
|
2003-08-15 |
2005-03-03 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
AR045342A1
(es)
|
2003-08-15 |
2005-10-26 |
Merck & Co Inc |
Inhibidores de quinesina mitotica
|
|
JP2007502775A
(ja)
|
2003-08-15 |
2007-02-15 |
メルク エンド カムパニー インコーポレーテッド |
有糸分裂キネシン阻害剤
|
|
CA2539042A1
(en)
|
2003-09-24 |
2005-04-07 |
Merck Sharp & Dohme Limited |
Gamma-secretase inhibitors
|
|
US7294640B2
(en)
|
2004-02-06 |
2007-11-13 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
|
WO2005100344A1
(en)
|
2004-04-09 |
2005-10-27 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
|
WO2005100356A1
(en)
|
2004-04-09 |
2005-10-27 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
|
WO2006001956A2
(en)
|
2004-05-20 |
2006-01-05 |
The Board Of Trustees Of The University Of Illinois |
Compositions for inhibiting cell growth and inducing apoptosis in cancer cells and methods of use thereof
|
|
US20070077245A1
(en)
*
|
2004-08-04 |
2007-04-05 |
The Brigham And Women's Hospital, Inc. |
NOTCH mutations leading to increased receptor signaling
|
|
AU2005302846A1
(en)
*
|
2004-11-10 |
2006-05-18 |
Hubrecht Laboratorium |
Treatment of an intestinal adenoma and/or adenocarcinoma by inhibition of notch pathway activation
|