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ATE439367T1 - Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen - Google Patents

Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen

Info

Publication number
ATE439367T1
ATE439367T1 AT05739739T AT05739739T ATE439367T1 AT E439367 T1 ATE439367 T1 AT E439367T1 AT 05739739 T AT05739739 T AT 05739739T AT 05739739 T AT05739739 T AT 05739739T AT E439367 T1 ATE439367 T1 AT E439367T1
Authority
AT
Austria
Prior art keywords
treatment
microbial infections
ester bonded
macrolides
macrolides suitable
Prior art date
Application number
AT05739739T
Other languages
English (en)
Inventor
Sulejman Alihodzic
Stjepan Mutak
Drazen Pavlovic
Ivana Palej
Vlado Stimac
Samra Kapic
Adrijana Vinter
Skugor Maja Matanovic
Original Assignee
Glaxosmithkline Zagreb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Zagreb filed Critical Glaxosmithkline Zagreb
Application granted granted Critical
Publication of ATE439367T1 publication Critical patent/ATE439367T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT05739739T 2004-05-06 2005-05-02 Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen ATE439367T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US56940204P 2004-05-06 2004-05-06
US58111804P 2004-06-18 2004-06-18
PCT/IB2005/001186 WO2005108412A1 (en) 2004-05-06 2005-05-02 Ester linked macrolides useful for the treatment of microbial infections

Publications (1)

Publication Number Publication Date
ATE439367T1 true ATE439367T1 (de) 2009-08-15

Family

ID=34967616

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05739739T ATE439367T1 (de) 2004-05-06 2005-05-02 Estergebundene makrolide, die sich für die behandlung von mikrobiellen infektionen eignen

Country Status (16)

Country Link
US (1) US20080255060A1 (de)
EP (1) EP1756135B1 (de)
JP (1) JP2007536371A (de)
AR (1) AR049269A1 (de)
AT (1) ATE439367T1 (de)
AU (1) AU2005240849B2 (de)
BR (1) BRPI0510328A (de)
CA (1) CA2566085A1 (de)
DE (1) DE602005015963D1 (de)
ES (1) ES2331739T3 (de)
IL (1) IL178876A0 (de)
MA (1) MA28640B1 (de)
MX (1) MXPA06012923A (de)
NO (1) NO20065662L (de)
RU (1) RU2006143051A (de)
WO (1) WO2005108412A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2529817C (en) 2003-03-10 2013-02-12 Optimer Pharmaceuticals, Inc. Novel antibacterial agents
WO2006120541A1 (en) * 2005-05-10 2006-11-16 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Ether linked macrolides useful for the treatment of microbial infections
RU2422453C2 (ru) * 2006-12-05 2011-06-27 Пфайзер Инк. Полиморфы мотилида
AU2008316830B2 (en) 2007-10-25 2016-03-17 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
WO2010048600A1 (en) 2008-10-24 2010-04-29 Cempra Pharmaceuticals, Inc. Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
US9480679B2 (en) 2009-09-10 2016-11-01 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
EP2571506B1 (de) * 2010-05-20 2017-05-10 Cempra Pharmaceuticals, Inc. Verfahren zur herstellung von makroliden und ketoliden sowie zwischenprodukte dafür
KR20130120458A (ko) 2010-09-10 2013-11-04 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
WO2013148891A1 (en) 2012-03-27 2013-10-03 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
EP2968801B1 (de) 2013-03-14 2018-09-26 Cempra Pharmaceuticals, Inc. Verfahren zur behandlung von atemwegserkrankungen und formulierungen dafür
MX356772B (es) 2013-03-15 2018-06-13 Cempra Pharmaceuticals Inc Procesos convergentes para la preparacion de agentes antibacterianos macrolidos.
GB201608236D0 (en) 2016-05-11 2016-06-22 Fidelta D O O Seco macrolide compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0127349D0 (en) * 2001-11-14 2002-01-02 Glaxo Group Ltd Macrolides
GB0225384D0 (en) * 2002-10-31 2002-12-11 Glaxo Group Ltd Novel compounds
CL2004001012A1 (es) * 2003-05-13 2005-03-18 Glaxo Group Ltd Compuestos derivados de macrolidos de 14 o 15 miembros, sustituidos en posicion 4"; procedimiento para su preparacion; composicion farmaceutica que lo comprende; y su uso para el tratamiento o profilaxis de infecciones microbianas sistemicas o topica
GB0310984D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
GB0310979D0 (en) * 2003-05-13 2003-06-18 Glaxo Group Ltd Novel compounds
WO2006120541A1 (en) * 2005-05-10 2006-11-16 Glaxosmithkline Istrazivacki Centar Zagreb D.O.O. Ether linked macrolides useful for the treatment of microbial infections

Also Published As

Publication number Publication date
BRPI0510328A (pt) 2007-10-23
JP2007536371A (ja) 2007-12-13
MA28640B1 (fr) 2007-06-01
US20080255060A1 (en) 2008-10-16
RU2006143051A (ru) 2008-06-20
IL178876A0 (en) 2007-03-08
EP1756135B1 (de) 2009-08-12
AU2005240849A1 (en) 2005-11-17
AU2005240849B2 (en) 2008-10-23
DE602005015963D1 (de) 2009-09-24
AR049269A1 (es) 2006-07-12
NO20065662L (no) 2007-01-16
MXPA06012923A (es) 2007-07-18
CA2566085A1 (en) 2005-11-17
WO2005108412A1 (en) 2005-11-17
EP1756135A1 (de) 2007-02-28
ES2331739T3 (es) 2010-01-14

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