[go: up one dir, main page]

ATE435654T1 - Manipulierte proteine zum analyten nachweis - Google Patents

Manipulierte proteine zum analyten nachweis

Info

Publication number
ATE435654T1
ATE435654T1 AT99935583T AT99935583T ATE435654T1 AT E435654 T1 ATE435654 T1 AT E435654T1 AT 99935583 T AT99935583 T AT 99935583T AT 99935583 T AT99935583 T AT 99935583T AT E435654 T1 ATE435654 T1 AT E435654T1
Authority
AT
Austria
Prior art keywords
analyte detection
manipulated
proteins
analyte
manipulated proteins
Prior art date
Application number
AT99935583T
Other languages
English (en)
Inventor
Joseph Lakowicz
Leah Tolosa
Lisa Eichhorn
Govind Rao
Original Assignee
Univ Maryland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Maryland filed Critical Univ Maryland
Application granted granted Critical
Publication of ATE435654T1 publication Critical patent/ATE435654T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/968High energy substrates, e.g. fluorescent, chemiluminescent, radioactive

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
AT99935583T 1998-07-17 1999-07-15 Manipulierte proteine zum analyten nachweis ATE435654T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9318898P 1998-07-17 1998-07-17
US10423798P 1998-10-14 1998-10-14
PCT/US1999/015998 WO2000003727A1 (en) 1998-07-17 1999-07-15 Engineered proteins for analyte sensing

Publications (1)

Publication Number Publication Date
ATE435654T1 true ATE435654T1 (de) 2009-07-15

Family

ID=26787240

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99935583T ATE435654T1 (de) 1998-07-17 1999-07-15 Manipulierte proteine zum analyten nachweis

Country Status (9)

Country Link
US (1) US6197534B1 (de)
EP (1) EP1098658B1 (de)
AT (1) ATE435654T1 (de)
AU (1) AU759888B2 (de)
CA (1) CA2336985C (de)
DE (1) DE69941085D1 (de)
DK (1) DK1098658T3 (de)
ES (1) ES2329850T3 (de)
WO (1) WO2000003727A1 (de)

Families Citing this family (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6120460A (en) * 1996-09-04 2000-09-19 Abreu; Marcio Marc Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions
US6544193B2 (en) * 1996-09-04 2003-04-08 Marcio Marc Abreu Noninvasive measurement of chemical substances
US20020158212A1 (en) * 1998-04-17 2002-10-31 French Todd E. Apparatus and methods for time-resolved optical spectroscopy
US6922576B2 (en) * 1998-06-19 2005-07-26 Becton, Dickinson And Company Micro optical sensor device
US6535753B1 (en) * 1998-08-20 2003-03-18 Microsense International, Llc Micro-invasive method for painless detection of analytes in extra-cellular space
WO2001013783A1 (en) 1999-08-26 2001-03-01 Novartis Ag Ocular analyte sensor
US7374896B2 (en) * 2001-08-28 2008-05-20 Allergan, Inc. GFP-SNAP25 fluorescence release assay for botulinum neurotoxin protease activity
US8022172B2 (en) * 2001-08-28 2011-09-20 Allergan, Inc. Luminescence resonance energy transfer (LRET) assays for clostridial toxin activity
US7332567B2 (en) * 2001-08-28 2008-02-19 Allergan, Inc. Fret protease assays for clostridial toxins
JP4358626B2 (ja) * 2001-08-28 2009-11-04 デューク ユニバーシティ バイオセンサー
EP2284195A1 (de) * 2001-09-18 2011-02-16 Carnegie Institution Of Washington Fusionsproteine zur Detektion von Analyten
US20030232383A1 (en) * 2001-11-02 2003-12-18 Sylvia Daunert Novel reagentless sensing system for measuring carbohydrates based on the galactose/glucose binding protein
US20030153026A1 (en) * 2002-01-04 2003-08-14 Javier Alarcon Entrapped binding protein as biosensors
US20050239155A1 (en) * 2002-01-04 2005-10-27 Javier Alarcon Entrapped binding protein as biosensors
US7064103B2 (en) * 2002-01-04 2006-06-20 Becton, Dickinson And Company Binding protein as biosensors
US6855556B2 (en) * 2002-01-04 2005-02-15 Becton, Dickinson And Company Binding protein as biosensors
US7851593B2 (en) * 2002-01-04 2010-12-14 Becton, Dickinson And Company Binding proteins as biosensors
US9848815B2 (en) 2002-04-22 2017-12-26 Geelux Holdings, Ltd. Apparatus and method for measuring biologic parameters
IL164685A0 (en) 2002-04-22 2005-12-18 Marcio Marc Aurelio Martins Ab Apparatus and method for measuring biologic parameters
US8328420B2 (en) * 2003-04-22 2012-12-11 Marcio Marc Abreu Apparatus and method for measuring biologic parameters
US20030232370A1 (en) * 2002-04-22 2003-12-18 Trifiro Mark A. Glucose sensor and uses thereof
US8849379B2 (en) * 2002-04-22 2014-09-30 Geelux Holdings, Ltd. Apparatus and method for measuring biologic parameters
US20050118726A1 (en) * 2002-08-26 2005-06-02 Schultz Jerome S. System and method for detecting bioanalytes and method for producing a bioanalyte sensor
US7244394B2 (en) 2002-10-03 2007-07-17 Novartis Ag Methods and kits for assays of analytes of interest in tears
WO2004036176A2 (en) * 2002-10-16 2004-04-29 Duke University Biosensor
ATE412177T1 (de) * 2002-12-20 2008-11-15 Univ Wuerzburg J Maximilians Millisekunden-aktivationsschalter für 7- transmembran-proteine
EP1620548A2 (de) * 2003-05-07 2006-02-01 Duke University Proteinkonstruktion für rezeptor-liganden-erkennung und -bindung
WO2004101769A2 (en) * 2003-05-09 2004-11-25 University Of Maryland Baltimore County Proteins, sensors, and methods of characterizing analytes using the same
WO2005019811A2 (en) * 2003-08-26 2005-03-03 Blueshift Biotechnologies, Inc. Time dependent fluorescence measurements
US7214190B1 (en) * 2003-09-09 2007-05-08 Kitchener Clark Wilson Apparatus and method for noninvasive monitoring of analytes in body fluids
US7787923B2 (en) * 2003-11-26 2010-08-31 Becton, Dickinson And Company Fiber optic device for sensing analytes and method of making same
US20050112685A1 (en) * 2003-11-26 2005-05-26 Amiss Terry J. Compositions and methods for measuring analyte concentrations
US7496392B2 (en) 2003-11-26 2009-02-24 Becton, Dickinson And Company Fiber optic device for sensing analytes
US20050264805A1 (en) * 2004-02-09 2005-12-01 Blueshift Biotechnologies, Inc. Methods and apparatus for scanning small sample volumes
US10227063B2 (en) 2004-02-26 2019-03-12 Geelux Holdings, Ltd. Method and apparatus for biological evaluation
US7563891B2 (en) * 2004-05-21 2009-07-21 Becton, Dickinson & Company Long wavelength thiol-reactive fluorophores
KR101297145B1 (ko) 2004-06-01 2013-08-21 크와라타 트레이딩 리미티드 줄기세포를 사용한 시험관내 기술
EP1754059B1 (de) * 2004-06-09 2010-08-04 Becton, Dickinson and Company Sensor für mehrere analyte
CA2570035C (en) * 2004-06-14 2013-08-13 Eyesense Ag Combined apparatus for measuring the blood glucose level from an ocular fluid
US7141378B2 (en) * 2004-07-02 2006-11-28 Blueshift Biotechnologies, Inc. Exploring fluorophore microenvironments
US7951357B2 (en) * 2004-07-14 2011-05-31 Glusense Ltd. Implantable power sources and sensors
US7399607B2 (en) * 2004-09-22 2008-07-15 Allergan, Inc. Fluorescence polarization assays for determining clostridial toxin activity
EP1815246A4 (de) * 2004-10-14 2009-12-16 Carnegie Inst Of Washington Entwicklung von empfindlichen fret-sensoren und verwendungsverfahren dafür
ATE540048T1 (de) * 2004-10-14 2012-01-15 Carnegie Inst Of Washington Neurotransmittersensoren und verfahren zu ihrer verwendung
US20090035800A1 (en) * 2004-12-24 2009-02-05 Aartsma T J Novel Use of Fluorescence Resonance Energy Transfer
WO2006096213A1 (en) * 2005-03-03 2006-09-14 Carnegie Institution Of Washington Polyamine sensors and methods of using the same
WO2006096214A1 (en) * 2005-03-04 2006-09-14 Carnegie Institution Of Washington Environmentally stable sensors and methods of using the same
WO2006096746A1 (en) * 2005-03-11 2006-09-14 Becton, Dickinson And Company Entrapped binding protein as biosensors
US20060224056A1 (en) * 2005-03-30 2006-10-05 Kermani Mahyar Z Method for monitoring an implanted fluorescent light-emitting bead
US7687263B2 (en) 2005-05-11 2010-03-30 Becton, Dickinson And Company In vitro tumor angiogenesis model
KR100739529B1 (ko) * 2005-07-25 2007-07-13 한국생명공학연구원 세포내 맥아당의 정량적 측정을 위한 맥아당 바이오센서
US20070038045A1 (en) * 2005-08-09 2007-02-15 Hayter Paul G Method for monitoring an implanted fluorescent light-emitting bead
US20070111196A1 (en) * 2005-08-19 2007-05-17 Javier Alarcon Sterilization of Biosensors
ATE456798T1 (de) * 2005-10-12 2010-02-15 Allergan Inc Tests der molekularen oder subzellulären interaktivität unter verwendung von depolarisierung nach resonanzenergietransfer (daret)
JP5148497B2 (ja) * 2005-10-14 2013-02-20 カーネギー インスチチューション オブ ワシントン スクロースバイオセンサーおよびそれを用いる方法
AU2005337168B2 (en) * 2005-10-14 2012-07-05 Carnegie Institution Of Washington Phosphate biosensors and methods of using the same
EP1951110B1 (de) 2005-10-24 2012-10-03 Marcio Marc Aurelio Martins Abreu Vorrichtung zur messung biologischer parameter
US20080311047A1 (en) * 2005-11-16 2008-12-18 Thijs Kaper Multimetric Biosensors and Methods of Using Same
US8158340B2 (en) 2005-12-28 2012-04-17 Corning Incorporated Methods for detecting conformational changes in bioentities
TW200734462A (en) 2006-03-08 2007-09-16 In Motion Invest Ltd Regulating stem cells
DK2029799T3 (da) 2006-04-20 2012-12-10 Becton Dickinson Co Termostabile proteiner og fremgangsmåder til fremstilling og anvendelse heraf
US20090093758A1 (en) 2006-07-24 2009-04-09 Yossi Gross Fibroid treatment apparatus and method
WO2008141241A1 (en) 2007-05-10 2008-11-20 Glumetrics, Inc. Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement
JP5453248B2 (ja) * 2007-05-22 2014-03-26 ベクトン・ディキンソン・アンド・カンパニー 代謝産物を検出するために比率測定蛍光応答を有する色素
WO2009021052A1 (en) * 2007-08-06 2009-02-12 University Of Kentucky Research Foundation Polypeptides, systems, and methods useful for detecting glucose
EP2217316A4 (de) 2007-11-21 2013-01-16 Glumetrics Inc Verwendung eines intravaskulären equilibrium-sensors für enge glykämische kontrolle
US20100160749A1 (en) * 2008-12-24 2010-06-24 Glusense Ltd. Implantable optical glucose sensing
CA2756351A1 (en) 2009-03-26 2010-09-30 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona, Acti Ng For And On Behalf Of Arizona State University Integrated device for surface-contact sampling, extraction and electrochemical measurements
US8403953B2 (en) * 2009-07-27 2013-03-26 Fibro Control, Inc. Balloon with rigid tube for occluding the uterine artery
EP2483679A4 (de) 2009-09-30 2013-04-24 Glumetrics Inc Sensoren mit thrombenresistenter beschichtung
US8741591B2 (en) 2009-10-09 2014-06-03 The Research Foundation For The State University Of New York pH-insensitive glucose indicator protein
US8467843B2 (en) 2009-11-04 2013-06-18 Glumetrics, Inc. Optical sensor configuration for ratiometric correction of blood glucose measurement
EP2545373B1 (de) * 2010-03-11 2022-08-24 Medtronic Minimed, Inc. Messung von analytkonzentrationen einschliesslich temperatur- und ph-korrektur
US20120130209A1 (en) * 2010-11-24 2012-05-24 Biotronik Se & Co. Kg Implantable Sensor Unit
US20140178895A1 (en) * 2011-03-23 2014-06-26 Saurabh Rajendra Nirantar Recombinant protein biosensors and a method for detecting the presence of an analyte molecule
US9037205B2 (en) 2011-06-30 2015-05-19 Glusense, Ltd Implantable optical glucose sensing
EP2831583B1 (de) 2012-03-28 2019-12-18 Becton, Dickinson and Company Hydrogelhaftung an geformten polymeren
AU2013204332B2 (en) 2012-04-16 2015-07-16 Commonwealth Scientific And Industrial Research Organisation Methods and systems for detecting an analyte or classifying a sample
WO2014137993A1 (en) * 2013-03-04 2014-09-12 David Reed Markle METHODS FOR USE IN A CALIBRATION-FREE ABSORBANCE SENSOR FOR MEASURING pH AND pCO2
US20140350370A1 (en) * 2013-04-08 2014-11-27 The Texas A&M University System Glucose sensing assay
EP3055659A4 (de) 2013-10-11 2017-12-06 Marcio Marc Abreu Verfahren und vorrichtung für biologische evaluierung
JP2017501844A (ja) 2014-01-10 2017-01-19 マーシオ マーク アブリュー Abreu脳熱トンネルの赤外線出力を測定するためのデバイス
JP2017505657A (ja) 2014-01-10 2017-02-23 マーシオ マーク アブリュー Abreu脳トンネルでモニタして治療を提供するデバイス
JP2017503604A (ja) 2014-01-22 2017-02-02 マーシオ マーク アブリュー Abreu脳熱トンネルでの治療を提供するように構成されたデバイス
WO2016036877A1 (en) * 2014-09-02 2016-03-10 Pharmozyme, Inc. Genetic detection platform
WO2016054079A1 (en) 2014-09-29 2016-04-07 Zyomed Corp. Systems and methods for blood glucose and other analyte detection and measurement using collision computing
EP3206567A1 (de) 2014-10-13 2017-08-23 Glusense, Ltd. Analytmessvorrichtung
WO2016145215A1 (en) 2015-03-10 2016-09-15 Marcio Marc Abreu Devices, apparatuses, systems, and methods for measuring temperature of an abtt terminus
US11156615B2 (en) * 2015-11-20 2021-10-26 Duke University Glucose biosensors and uses thereof
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
WO2017183030A1 (en) 2016-04-20 2017-10-26 Glusense Ltd. Fret-based glucose-detection molecules
JP2020510406A (ja) 2016-11-14 2020-04-09 コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション プロテアーゼセンサー分子
PL3665481T3 (pl) * 2017-08-08 2024-02-05 PPB Technology Pty Ltd Czujniki węglowodanów
CA3157995A1 (en) 2019-10-25 2021-04-29 Cercacor Laboratories, Inc. Indicator compounds, devices comprising indicator compounds, and methods of making and using the same
USD1084670S1 (en) * 2022-06-16 2025-07-22 3M Innovative Properties Company Lint roller handle

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681923A (en) * 1995-10-06 1997-10-28 Platt; David Tumor derived carbohydrate binding protein
CA2283629C (en) 1997-03-14 2010-08-03 Roger Y. Tsien Fluorescent protein sensors for detection of analytes
ATE410683T1 (de) * 1997-12-31 2008-10-15 Univ Duke Glukosebiosensor

Also Published As

Publication number Publication date
CA2336985C (en) 2011-01-04
EP1098658B1 (de) 2009-07-08
DK1098658T3 (da) 2009-11-09
CA2336985A1 (en) 2000-01-27
DE69941085D1 (de) 2009-08-20
WO2000003727A1 (en) 2000-01-27
ES2329850T3 (es) 2009-12-01
AU759888B2 (en) 2003-05-01
EP1098658A1 (de) 2001-05-16
EP1098658A4 (de) 2008-01-02
WO2000003727A9 (en) 2000-07-20
AU5103399A (en) 2000-02-07
US6197534B1 (en) 2001-03-06

Similar Documents

Publication Publication Date Title
ATE435654T1 (de) Manipulierte proteine zum analyten nachweis
DE60118527D1 (de) Sensible und multiplexe diagnostische tests zur proteinanalyse
DE69840107D1 (de) Glukosebiosensor
WO2004101769A3 (en) Proteins, sensors, and methods of characterizing analytes using the same
PT1077634E (pt) Monitorizacao de substancias fisiologicas a analisar
WO2004070020A3 (en) Glyphosate tolerant alfalfa events and methods for detection thereof
WO2001042502A3 (en) Methods for disease detection
DK0645015T3 (da) Forbedringer ved eller i forbindelse med analytpåvisning.
ATE368125T1 (de) Verfahren zur erkennung von einzel-nukleotid- polymorphismen
TW200720441A (en) New labelling strategies for the sensitive detection of analytes
ATE325203T1 (de) Nachweis und identifikation von bakteriengruppen
ECSP056124A (es) Método y dispositivo para detectar analitos volátiles en muestras de aire
DE60325382D1 (de) Verfahren zur diagnose von gebärmutterhalskrebs
ATE229571T1 (de) Nachweis und identifizierung von nicht-polio enteroviren
DK1400589T3 (da) Fremgangsmåde til påvisning af prokaryotisk DNA
EP0843019A3 (de) Verfahren zur Bestimmung einer spezifischen Nukleinsäuresequenz, und ein Reagenz für diesen Zweck
NO964084L (no) Påvisning av analytter
WO2006071970A3 (en) Methods for the detection of analytes in a sample
WO2002077285A3 (en) Methods of determining the presence of polynucleotides employing amplification
WO2004016802A3 (en) Methods and apparatus for preparing and assaying biological samples to determine protein concentration
DE50203136D1 (de) Verfahren zum Nachweis von Analyten in Proben mittels Analysenelementen
WO2002014857A3 (en) Direct selection of protein complexes relevant to the physiological or diagnostic context of a biological specimen
DE69920981D1 (de) Knorpelresorptionsassays
EP1241269A3 (de) Verfahren zum Nachweiss von REG-ähnliches Protein und dafür kodierende Nukleinäuren
WO2003027680A3 (en) Makrophage-based biosensor for detection of toxic substances

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties