ATE409173T1 - Radikalfänger bei der fluorierung von iodiniumsalz - Google Patents
Radikalfänger bei der fluorierung von iodiniumsalzInfo
- Publication number
- ATE409173T1 ATE409173T1 AT04806112T AT04806112T ATE409173T1 AT E409173 T1 ATE409173 T1 AT E409173T1 AT 04806112 T AT04806112 T AT 04806112T AT 04806112 T AT04806112 T AT 04806112T AT E409173 T1 ATE409173 T1 AT E409173T1
- Authority
- AT
- Austria
- Prior art keywords
- iodonium salts
- fluoration
- reaction
- solid phase
- fluoridation
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title 1
- 238000006243 chemical reaction Methods 0.000 abstract 3
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical group I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 abstract 3
- 150000003254 radicals Chemical class 0.000 abstract 3
- 238000000354 decomposition reaction Methods 0.000 abstract 2
- 238000004334 fluoridation Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000007790 solid phase Substances 0.000 abstract 2
- 150000001501 aryl fluorides Chemical class 0.000 abstract 1
- 230000037361 pathway Effects 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
- Liquid Crystal (AREA)
- Seasonings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0329716.5A GB0329716D0 (en) | 2003-12-23 | 2003-12-23 | Radical trap |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE409173T1 true ATE409173T1 (de) | 2008-10-15 |
Family
ID=30776291
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04806112T ATE409173T1 (de) | 2003-12-23 | 2004-12-17 | Radikalfänger bei der fluorierung von iodiniumsalz |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7642373B2 (de) |
| EP (1) | EP1697279B1 (de) |
| JP (1) | JP4809244B2 (de) |
| CN (1) | CN100415696C (de) |
| AT (1) | ATE409173T1 (de) |
| DE (1) | DE602004016771D1 (de) |
| ES (1) | ES2313117T3 (de) |
| GB (1) | GB0329716D0 (de) |
| WO (1) | WO2005061415A1 (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0407952D0 (en) * | 2004-04-08 | 2004-05-12 | Amersham Plc | Fluoridation method |
| GB0525949D0 (en) | 2005-12-21 | 2006-02-01 | Hammersmith Imanet Ltd | Pet radiotracers |
| EP2192928A4 (de) * | 2007-10-03 | 2011-04-06 | Ge Healthcare Ltd | Perfluor-aryliodonium-salze in einer nukleophilen aromatischen 18f-fluorierung |
| US8980221B2 (en) * | 2008-01-03 | 2015-03-17 | Ge Healthcare Limited | Fluoride processing method |
| GB0808986D0 (en) | 2008-05-16 | 2008-06-25 | Univ Newcastle | Formation of 18F and 19F fluoroarenes bearing reactive functionalities |
| WO2010015340A1 (en) * | 2008-08-06 | 2010-02-11 | Bayer Schering Pharma Aktiengesellschaft | Daa-pyridine as peripheral benzodiazepine receptor ligand for diagnostic imaging and pharmaceutical treatment |
| GB0814893D0 (en) * | 2008-08-14 | 2008-09-17 | Ge Healthcare Ltd | Improved fluoridation of iodonium salts |
| US9302990B2 (en) | 2008-10-21 | 2016-04-05 | Nutech Ventures | Fluorination of aromatic ring systems |
| CA2741967A1 (en) | 2008-10-21 | 2010-04-29 | Stephen Dimagno | Fluorination of aromatic ring systems |
| GB0905438D0 (en) | 2009-03-30 | 2009-05-13 | Ge Healthcare Ltd | Radiolabelling reagents and methods |
| EP2417119B1 (de) * | 2009-04-08 | 2016-12-21 | The Regents of The University of California | Trägerarme nukleophile [ f-18]fluorierung aromatischer verbindungen |
| US8377704B2 (en) | 2009-10-20 | 2013-02-19 | Nutech Ventures | Detection and quantification of anions |
| US8546578B2 (en) | 2010-02-04 | 2013-10-01 | Nutech Ventures | Iodonium Cyclophanes for SECURE arene functionalization |
| WO2011141515A1 (en) | 2010-05-14 | 2011-11-17 | Bayer Pharma Aktiengesellschaft | Diagnostic agents for amyloid beta imaging |
| KR101441406B1 (ko) * | 2011-05-25 | 2014-11-04 | 주식회사 바이오이미징코리아 | 디아릴이오도늄 염 전구체를 이용한 플로오린-18이 표지된 플루마제닐의 제조 방법 |
| AU2013334166A1 (en) * | 2012-10-27 | 2015-05-28 | Ground Fluor Pharmaceuticals, Inc. | Processes and reagents for making diaryliodonium salts |
| EP2821383B1 (de) * | 2013-07-02 | 2017-08-30 | Trasis S.A. | Stabilisierung von radiosynthetischen Zwischenprodukten |
| WO2015157597A1 (en) * | 2014-04-11 | 2015-10-15 | The Regents Of The University Of Michigan | Copper catalyzed [18f]fluorination of iodonium salts |
| CN105237483B (zh) * | 2015-11-10 | 2018-04-20 | 东华大学 | 一种对称型嘧啶基碘鎓盐及其制备方法 |
| FR3054445B1 (fr) * | 2016-07-26 | 2019-07-05 | Laboratoires Cyclopharma | Synthese d'une composition d'agent radioactif |
| US10695450B2 (en) | 2016-07-26 | 2020-06-30 | Laboratoires Cyclopharma | Synthesis of a radioactive agent composition |
| JP2021500374A (ja) * | 2017-10-24 | 2021-01-07 | ルネラ・バイオテック・インコーポレーテッド | 標的フラビン含有酵素がミトコンドリア呼吸を阻害することにより癌幹細胞（ｃｓｃｓ）を排除するミトフラボスチン |
| GB201805253D0 (en) | 2018-03-29 | 2018-05-16 | Ge Healthcare Ltd Ip | Solid phase extraction |
| JP7627551B2 (ja) * | 2019-07-01 | 2025-02-06 | 住友化学株式会社 | 塩、酸発生剤、レジスト組成物及びレジストパターンの製造方法 |
| JP7558694B2 (ja) * | 2019-07-01 | 2024-10-01 | 住友化学株式会社 | 塩、酸発生剤、レジスト組成物及びレジストパターンの製造方法 |
| JP2021008455A (ja) * | 2019-07-01 | 2021-01-28 | 住友化学株式会社 | カルボン酸塩、カルボン酸発生剤、レジスト組成物及びレジストパターンの製造方法 |
| JP7556709B2 (ja) * | 2019-07-01 | 2024-09-26 | 住友化学株式会社 | カルボン酸塩、カルボン酸発生剤、レジスト組成物及びレジストパターンの製造方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS52133994A (en) * | 1976-04-29 | 1977-11-09 | Daikin Ind Ltd | Method of fluorination |
| JP3165775B2 (ja) * | 1994-08-31 | 2001-05-14 | 日本鋼管株式会社 | フッ素放射性同位元素標識ｌ−ドーパの製造方法 |
| JP3171036B2 (ja) * | 1994-11-16 | 2001-05-28 | 日本鋼管株式会社 | フッ素放射性同位元素標識ドーパミンの製造方法 |
| GB0115927D0 (en) * | 2001-06-29 | 2001-08-22 | Nycomed Amersham Plc | Solid-phase nucleophilic fluorination |
| GB0206750D0 (en) * | 2002-03-22 | 2002-05-01 | Amersham Plc | Radiofluorination methods |
| DE10346228B4 (de) * | 2003-09-25 | 2009-04-09 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Herstellung von [18F]fluormarkierten aromatischen L-Aminosäuren |
| GB0407952D0 (en) * | 2004-04-08 | 2004-05-12 | Amersham Plc | Fluoridation method |
-
2003
- 2003-12-23 GB GBGB0329716.5A patent/GB0329716D0/en not_active Ceased
-
2004
- 2004-12-17 US US10/559,879 patent/US7642373B2/en not_active Expired - Fee Related
- 2004-12-17 CN CNB2004800384699A patent/CN100415696C/zh not_active Expired - Fee Related
- 2004-12-17 AT AT04806112T patent/ATE409173T1/de not_active IP Right Cessation
- 2004-12-17 WO PCT/GB2004/005304 patent/WO2005061415A1/en not_active Ceased
- 2004-12-17 EP EP04806112A patent/EP1697279B1/de not_active Expired - Lifetime
- 2004-12-17 JP JP2006546303A patent/JP4809244B2/ja not_active Expired - Fee Related
- 2004-12-17 ES ES04806112T patent/ES2313117T3/es not_active Expired - Lifetime
- 2004-12-17 DE DE602004016771T patent/DE602004016771D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2007515465A (ja) | 2007-06-14 |
| GB0329716D0 (en) | 2004-01-28 |
| DE602004016771D1 (de) | 2008-11-06 |
| CN100415696C (zh) | 2008-09-03 |
| CN1898184A (zh) | 2007-01-17 |
| WO2005061415A1 (en) | 2005-07-07 |
| EP1697279A1 (de) | 2006-09-06 |
| EP1697279B1 (de) | 2008-09-24 |
| ES2313117T3 (es) | 2009-03-01 |
| US20060292060A1 (en) | 2006-12-28 |
| US7642373B2 (en) | 2010-01-05 |
| JP4809244B2 (ja) | 2011-11-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |