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ATE406439T1 - Eukaryontische signalsequenzen für polypeptid- expressions- und polypeptid- präsentationsbibliotheken - Google Patents

Eukaryontische signalsequenzen für polypeptid- expressions- und polypeptid- präsentationsbibliotheken

Info

Publication number
ATE406439T1
ATE406439T1 AT03739833T AT03739833T ATE406439T1 AT E406439 T1 ATE406439 T1 AT E406439T1 AT 03739833 T AT03739833 T AT 03739833T AT 03739833 T AT03739833 T AT 03739833T AT E406439 T1 ATE406439 T1 AT E406439T1
Authority
AT
Austria
Prior art keywords
polypeptide
signal sequences
eukaryontic
presentation libraries
expression
Prior art date
Application number
AT03739833T
Other languages
English (en)
Inventor
Jeff Gray
Joe Buechler
Uday Veeramallu
Original Assignee
Xoma Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xoma Technology Ltd filed Critical Xoma Technology Ltd
Application granted granted Critical
Publication of ATE406439T1 publication Critical patent/ATE406439T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/50—Fusion polypeptide containing protease site
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT03739833T 2002-02-13 2003-02-13 Eukaryontische signalsequenzen für polypeptid- expressions- und polypeptid- präsentationsbibliotheken ATE406439T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/076,802 US7094579B2 (en) 2002-02-13 2002-02-13 Eukaryotic signal sequences for prokaryotic expression

Publications (1)

Publication Number Publication Date
ATE406439T1 true ATE406439T1 (de) 2008-09-15

Family

ID=27732544

Family Applications (2)

Application Number Title Priority Date Filing Date
AT08163005T ATE533845T1 (de) 2002-02-13 2003-02-13 Eukaryotische signalsequenzen zur polypeptid- expression und polypeptid-anzeigebibliotheken
AT03739833T ATE406439T1 (de) 2002-02-13 2003-02-13 Eukaryontische signalsequenzen für polypeptid- expressions- und polypeptid- präsentationsbibliotheken

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT08163005T ATE533845T1 (de) 2002-02-13 2003-02-13 Eukaryotische signalsequenzen zur polypeptid- expression und polypeptid-anzeigebibliotheken

Country Status (9)

Country Link
US (5) US7094579B2 (de)
EP (2) EP2060628B1 (de)
JP (2) JP4303596B2 (de)
AT (2) ATE533845T1 (de)
AU (1) AU2003225578B2 (de)
CA (1) CA2475929C (de)
DE (1) DE60323210D1 (de)
DK (2) DK1481059T3 (de)
WO (1) WO2003068956A1 (de)

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EP1685247B1 (de) * 2003-10-03 2009-11-11 Promega Corporation Vektoren zur gerichteten klonierung
EP1737962B1 (de) * 2004-03-24 2010-09-01 Domantis Limited Universelles signalpeptid gas1
ES2612545T3 (es) 2004-12-07 2017-05-17 Lonza Ltd Sistema de expresión del operón melibiosa
EP1824980B1 (de) * 2004-12-07 2010-04-28 Lonza Ag Rhamnosepromotor-expressionssystem
WO2008008950A2 (en) * 2006-07-14 2008-01-17 Novozymes, Inc. Methods for producing secreted polypeptides having biological activity
GB0810154D0 (en) 2008-06-04 2008-07-09 Avecia Biolog Ltd Expression vector
WO2010040073A1 (en) * 2008-10-03 2010-04-08 Xoma Technology Ltd. Novel triple tag sequences and methods of use thereof
US8946128B2 (en) * 2009-02-25 2015-02-03 Nextera As Signal sequence-independent pIX phage display
WO2010117420A2 (en) 2009-03-30 2010-10-14 Pacific Biosciences Of California, Inc. Fret-labeled compounds and uses therefor
EP2658971A1 (de) 2010-12-28 2013-11-06 XOMA Technology Ltd. Zelloberflächendisplay mit pdz-domänen
DK2670847T3 (en) 2011-02-03 2017-01-16 Xoma Technology Ltd Methods and Materials for Improving Functional Protein Expression in Bacteria
US10228312B2 (en) 2012-02-23 2019-03-12 Juno Therapeutics Gmbh Chromatographic isolation of cells and other complex biological materials
RU2670491C2 (ru) * 2012-07-05 2018-10-23 Дженентек, Инк. Система экспрессии и секреции
MA45489A (fr) 2015-10-22 2018-08-29 Juno Therapeutics Gmbh Procédés de culture de cellules, kits et appareil associés
WO2017068419A2 (en) 2015-10-22 2017-04-27 Juno Therapeutics Gmbh Methods, kits, agents and apparatuses for transduction
ES2923755T3 (es) 2015-10-23 2022-09-30 Fred Hutchinson Cancer Center Procedimientos para crear sistemas de proteínas de dimerización inducidos químicamente para la regulación de eventos celulares
CN105734061B (zh) * 2016-03-25 2019-07-23 中国农业科学院生物技术研究所 从毕赤酵母中分离的鼠李糖诱导型启动子及其应用
WO2018197949A1 (en) 2017-04-27 2018-11-01 Juno Therapeutics Gmbh Oligomeric particle reagents and methods of use thereof
EP3444269A1 (de) 2017-08-17 2019-02-20 National Research Council of Canada Systeme und methoden für die produktion von diphteria-giftstoff-polypeptiden
CN112041486A (zh) 2017-12-11 2020-12-04 鲍鱼生物股份有限公司 周质空间中蛋白质的酵母展示
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics
IT201900006656A1 (it) 2019-05-08 2020-11-08 Salvagnini Italia Spa Macchina piegatrice per lamiere metalliche
JP7753236B2 (ja) * 2020-02-25 2025-10-14 モメンタ ファーマシューティカルズ インコーポレイテッド グリカンのシアリル化のための酵素
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine

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CN103929153B (zh) 2013-01-11 2016-12-28 北大方正集团有限公司 一种倍频处理方法和装置

Also Published As

Publication number Publication date
US20100009857A1 (en) 2010-01-14
EP1481059A4 (de) 2006-02-01
JP2005517407A (ja) 2005-06-16
DK2060628T3 (da) 2012-01-23
DK1481059T3 (da) 2009-01-12
EP1481059B1 (de) 2008-08-27
US20110224102A1 (en) 2011-09-15
US8476040B2 (en) 2013-07-02
ATE533845T1 (de) 2011-12-15
EP1481059A1 (de) 2004-12-01
CA2475929C (en) 2013-01-15
US20080214411A1 (en) 2008-09-04
US7977068B2 (en) 2011-07-12
EP2060628A1 (de) 2009-05-20
JP5190963B2 (ja) 2013-04-24
JP4303596B2 (ja) 2009-07-29
US7972811B2 (en) 2011-07-05
WO2003068956A1 (en) 2003-08-21
US20030228660A1 (en) 2003-12-11
JP2009131286A (ja) 2009-06-18
US20030162249A1 (en) 2003-08-28
DE60323210D1 (en) 2008-10-09
EP2060628B1 (de) 2011-11-16
US7094579B2 (en) 2006-08-22
US7396661B2 (en) 2008-07-08
AU2003225578A1 (en) 2003-09-04
AU2003225578B2 (en) 2008-04-03
CA2475929A1 (en) 2003-08-21

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