ATE490337T1 - Blutstillungstest - Google Patents
BlutstillungstestInfo
- Publication number
- ATE490337T1 ATE490337T1 AT06700777T AT06700777T ATE490337T1 AT E490337 T1 ATE490337 T1 AT E490337T1 AT 06700777 T AT06700777 T AT 06700777T AT 06700777 T AT06700777 T AT 06700777T AT E490337 T1 ATE490337 T1 AT E490337T1
- Authority
- AT
- Austria
- Prior art keywords
- plasmin
- thrombin
- specific
- cleavage
- measurable
- Prior art date
Links
- 108090000190 Thrombin Proteins 0.000 abstract 6
- 229940012957 plasmin Drugs 0.000 abstract 6
- 229960004072 thrombin Drugs 0.000 abstract 6
- 238000003556 assay Methods 0.000 abstract 2
- 238000003776 cleavage reaction Methods 0.000 abstract 2
- 230000001939 inductive effect Effects 0.000 abstract 2
- 239000011541 reaction mixture Substances 0.000 abstract 2
- 230000007017 scission Effects 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000010836 blood and blood product Substances 0.000 abstract 1
- 229940125691 blood product Drugs 0.000 abstract 1
- 229910001424 calcium ion Inorganic materials 0.000 abstract 1
- 230000023597 hemostasis Effects 0.000 abstract 1
- 150000003904 phospholipids Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases
- C12Q2337/20—Coumarin derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05075030 | 2005-01-07 | ||
| PCT/EP2006/000184 WO2006072602A1 (en) | 2005-01-07 | 2006-01-09 | Hemostasis assay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE490337T1 true ATE490337T1 (de) | 2010-12-15 |
Family
ID=35871110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06700777T ATE490337T1 (de) | 2005-01-07 | 2006-01-09 | Blutstillungstest |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8809006B2 (de) |
| EP (1) | EP1833982B1 (de) |
| JP (1) | JP4931826B2 (de) |
| AT (1) | ATE490337T1 (de) |
| CA (1) | CA2592748C (de) |
| DE (1) | DE602006018577D1 (de) |
| ES (1) | ES2357112T3 (de) |
| WO (1) | WO2006072602A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102006035899A1 (de) * | 2006-07-31 | 2008-02-07 | Dade Behring Marburg Gmbh | Polysacharid-Peptid-Konjugate zur Verwendung als Thrombinsubstrate |
| FR2917172B1 (fr) * | 2007-06-07 | 2014-01-03 | Inst Nat Sante Rech Med | Methode de mesure de l'activite plasmine des microparticules presentes dans un echantillon de fluide biologique et utilisation |
| US8261327B2 (en) * | 2007-07-12 | 2012-09-04 | Wayport, Inc. | Device-specific authorization at distributed locations |
| US20130065260A1 (en) * | 2009-11-06 | 2013-03-14 | The Regents Of The University Of Colorado, A Body Corporate | Compositions, Methods and Uses for Simultaneous Assay of Thrombin and Plasmin Generation |
| US9856510B2 (en) | 2010-12-14 | 2018-01-02 | Stichting Katholieke Universiteit | Chemiluminescence-based haemostasis assay |
| EP2465941A1 (de) * | 2010-12-20 | 2012-06-20 | Siemens Healthcare Diagnostics Products GmbH | Verfahren zur simultanen Bestimmung mehrerer Gerinnungsproteasen |
| FR2978164B1 (fr) * | 2011-07-22 | 2013-08-30 | Stago Diagnostica | Utilisation d'un substrat dans une methode pour mesurer l'activite des enzymes proteolytiques |
| FR2978163B1 (fr) * | 2011-07-22 | 2013-08-30 | Stago Diagnostica | Utilisation d'un substrat dans une methode pour mesurer l'activite des enzymes proteolytiques disponibles |
| US10200391B2 (en) * | 2015-09-23 | 2019-02-05 | AVAST Software s.r.o. | Detection of malware in derived pattern space |
| JP7101351B2 (ja) | 2016-04-28 | 2022-07-15 | シスメックス株式会社 | 血液検体の分析方法、血液検体分析用試薬及び試薬キット、並びに血液検体分析装置 |
| EP3363912B1 (de) | 2017-02-17 | 2020-10-28 | Synapse B.V. | Selbstkalibrierter assay zur bestimmung der erzeugung von proteolytischem enzym, dedizierte mittel und verwendungen davon |
| EP3867234A1 (de) | 2018-10-17 | 2021-08-25 | Enzyre B.V. | Neuartige chemilumineszente substrate für faktor xa |
| US20240426848A1 (en) * | 2021-10-29 | 2024-12-26 | National University Corporation Hamamatsu University School Of Medicine | Method of evaluating fibrinolytic resistance activity in blood plasma |
| WO2024153750A1 (en) | 2023-01-18 | 2024-07-25 | Enzyre B.V. | Luminescent detection of adamts13 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5096807A (en) * | 1985-03-06 | 1992-03-17 | Murex Corporation | Imaging immunoassay detection system with background compensation and its use |
| US5231006A (en) * | 1986-10-16 | 1993-07-27 | Behringwerke Aktiengesellschaft | Method for the determination of plasminogen |
| US5110727A (en) * | 1987-04-03 | 1992-05-05 | Cardiovascular Diagnostics, Inc. | Method for performing coagulation assays accurately, rapidly and simply, using dry chemical reagents and paramagnetic particles |
| NL8902406A (nl) | 1989-09-27 | 1991-04-16 | Hendrik Coenraad Hemker Prof D | Werkwijze voor het bepalen van de endogene trombinepotentiaal van plasma, en bloed alsmede een bij deze werkwijze te gebruiken kit. |
| US5510243A (en) * | 1994-06-21 | 1996-04-23 | Gelman Sciences, Inc. | Multiple chromogen enzyme targeting (MCET) for use in bacterial contamination monitoring |
| PT947585E (pt) * | 1998-03-19 | 2001-11-30 | Instrumentation Lab Spa | Metodo in vitro melhorado, kits e reagentes para a peaquisa de defeitos de coagulacao sanguinea |
| US6899877B2 (en) * | 1999-03-09 | 2005-05-31 | Minu, L.L.C. | Process for generating plasmin in the vitreous of the eye and inducing separation of the posterior hyaloid from the retina |
| US6245548B1 (en) * | 2000-03-09 | 2001-06-12 | American National Red Cross | Activation of pure prothrombin to thrombin with about 30% to about 40% sodium citrate |
| US7524826B2 (en) * | 2000-04-14 | 2009-04-28 | Mcmaster University And Hamilton Health Sciences Corporation | Method of inhibiting the generation of active thrombin on the surface of a cell within an atherosclerotic plaque |
| WO2003093831A1 (en) * | 2002-05-01 | 2003-11-13 | Synapse B.V. | Diagnostic test for determining the concentration of transient proteolytic activity in composite biological media |
| EP1537230A4 (de) * | 2002-09-09 | 2008-06-18 | Applera Corp | Fluoreszenz-enzymtestverfahren und -zusammensetzungen |
| US20080268483A1 (en) | 2004-09-22 | 2008-10-30 | The Regents Of The University Of Colorado | Methods for a Global Assay of Coagulation and Fibrinolysis |
-
2006
- 2006-01-09 JP JP2007549872A patent/JP4931826B2/ja not_active Expired - Fee Related
- 2006-01-09 DE DE602006018577T patent/DE602006018577D1/de active Active
- 2006-01-09 EP EP06700777A patent/EP1833982B1/de not_active Not-in-force
- 2006-01-09 WO PCT/EP2006/000184 patent/WO2006072602A1/en not_active Ceased
- 2006-01-09 AT AT06700777T patent/ATE490337T1/de active
- 2006-01-09 ES ES06700777T patent/ES2357112T3/es active Active
- 2006-01-09 CA CA2592748A patent/CA2592748C/en not_active Expired - Fee Related
-
2007
- 2007-07-09 US US11/774,843 patent/US8809006B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE602006018577D1 (de) | 2011-01-13 |
| EP1833982A1 (de) | 2007-09-19 |
| CA2592748A1 (en) | 2006-07-13 |
| JP2008526219A (ja) | 2008-07-24 |
| CA2592748C (en) | 2014-04-22 |
| ES2357112T3 (es) | 2011-04-18 |
| EP1833982B1 (de) | 2010-12-01 |
| US8809006B2 (en) | 2014-08-19 |
| US20080026365A1 (en) | 2008-01-31 |
| JP4931826B2 (ja) | 2012-05-16 |
| WO2006072602A1 (en) | 2006-07-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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