ATE478869T1 - DIAZABICYCLOALKAN DERIVATIVES AND THEIR MEDICAL USES - Google Patents
DIAZABICYCLOALKAN DERIVATIVES AND THEIR MEDICAL USESInfo
- Publication number
- ATE478869T1 ATE478869T1 AT07712214T AT07712214T ATE478869T1 AT E478869 T1 ATE478869 T1 AT E478869T1 AT 07712214 T AT07712214 T AT 07712214T AT 07712214 T AT07712214 T AT 07712214T AT E478869 T1 ATE478869 T1 AT E478869T1
- Authority
- AT
- Austria
- Prior art keywords
- diseases
- disorders
- derivatives
- nervous system
- disorders related
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 8
- 201000010099 disease Diseases 0.000 abstract 4
- 208000035475 disorder Diseases 0.000 abstract 4
- 210000003169 central nervous system Anatomy 0.000 abstract 2
- 230000001713 cholinergic effect Effects 0.000 abstract 2
- 210000001428 peripheral nervous system Anatomy 0.000 abstract 2
- 108010078791 Carrier Proteins Proteins 0.000 abstract 1
- 208000017701 Endocrine disease Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 102000019315 Nicotinic acetylcholine receptors Human genes 0.000 abstract 1
- 108050006807 Nicotinic acetylcholine receptors Proteins 0.000 abstract 1
- 208000002193 Pain Diseases 0.000 abstract 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000030172 endocrine system disease Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 102000005962 receptors Human genes 0.000 abstract 1
- 108020003175 receptors Proteins 0.000 abstract 1
- 230000016160 smooth muscle contraction Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
This invention relates to novel diaza-bicyclo-alkane derivatives, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200600210 | 2006-02-14 | ||
| US77332506P | 2006-02-15 | 2006-02-15 | |
| PCT/EP2007/051396 WO2007093600A1 (en) | 2006-02-14 | 2007-02-13 | Novel diazabicycloalkane derivatives and their medical use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE478869T1 true ATE478869T1 (en) | 2010-09-15 |
Family
ID=40413958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07712214T ATE478869T1 (en) | 2006-02-14 | 2007-02-13 | DIAZABICYCLOALKAN DERIVATIVES AND THEIR MEDICAL USES |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN101370809A (en) |
| AT (1) | ATE478869T1 (en) |
| DE (1) | DE602007008689D1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107188900B (en) * | 2017-05-27 | 2019-09-06 | 北京师范大学 | Ligand compound of α7 nicotinic acetylcholine receptor and its application |
-
2007
- 2007-02-13 CN CNA2007800027356A patent/CN101370809A/en active Pending
- 2007-02-13 AT AT07712214T patent/ATE478869T1/en not_active IP Right Cessation
- 2007-02-13 DE DE602007008689T patent/DE602007008689D1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN101370809A (en) | 2009-02-18 |
| DE602007008689D1 (en) | 2010-10-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |