ATE465747T1 - Rgd-angereicherte gelatineähnliche proteine zur verhinderung der blutplättchenaggregation - Google Patents
Rgd-angereicherte gelatineähnliche proteine zur verhinderung der blutplättchenaggregationInfo
- Publication number
- ATE465747T1 ATE465747T1 AT07111329T AT07111329T ATE465747T1 AT E465747 T1 ATE465747 T1 AT E465747T1 AT 07111329 T AT07111329 T AT 07111329T AT 07111329 T AT07111329 T AT 07111329T AT E465747 T1 ATE465747 T1 AT E465747T1
- Authority
- AT
- Austria
- Prior art keywords
- rgd
- enriched
- gelatine
- amino acids
- gelatines
- Prior art date
Links
- 230000002776 aggregation Effects 0.000 title 1
- 238000004220 aggregation Methods 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 229920000159 gelatin Polymers 0.000 abstract 8
- 235000019322 gelatine Nutrition 0.000 abstract 8
- 239000001828 Gelatine Substances 0.000 abstract 4
- 150000001413 amino acids Chemical class 0.000 abstract 4
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010035532 Collagen Proteins 0.000 abstract 1
- 238000004113 cell culture Methods 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 238000012377 drug delivery Methods 0.000 abstract 1
- 239000007943 implant Substances 0.000 abstract 1
- 102000006495 integrins Human genes 0.000 abstract 1
- 108010044426 integrins Proteins 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1658—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/222—Gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/043—Proteins; Polypeptides; Degradation products thereof
- A61L31/045—Gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
- C12N5/0075—General culture methods using substrates using microcarriers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Surgery (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03075906 | 2003-03-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE465747T1 true ATE465747T1 (de) | 2010-05-15 |
Family
ID=33041011
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07111329T ATE465747T1 (de) | 2003-03-28 | 2004-03-26 | Rgd-angereicherte gelatineähnliche proteine zur verhinderung der blutplättchenaggregation |
| AT07111303T ATE450548T1 (de) | 2003-03-28 | 2004-03-26 | Rgd-angereicherte gelatineähnliche proteine mit verstärkter zellbindung |
| AT04723872T ATE397626T1 (de) | 2003-03-28 | 2004-03-26 | Rgd-angereicherte gelatine-ähnliche proteine mit verstärkter zellbindung |
| AT07111368T ATE452649T1 (de) | 2003-03-28 | 2004-03-26 | Rgd-angereicherte, gelatine-ähnliche proteine zur verhinderung der zelladhäsion |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07111303T ATE450548T1 (de) | 2003-03-28 | 2004-03-26 | Rgd-angereicherte gelatineähnliche proteine mit verstärkter zellbindung |
| AT04723872T ATE397626T1 (de) | 2003-03-28 | 2004-03-26 | Rgd-angereicherte gelatine-ähnliche proteine mit verstärkter zellbindung |
| AT07111368T ATE452649T1 (de) | 2003-03-28 | 2004-03-26 | Rgd-angereicherte, gelatine-ähnliche proteine zur verhinderung der zelladhäsion |
Country Status (6)
| Country | Link |
|---|---|
| US (8) | US7517954B2 (de) |
| EP (7) | EP1608681B1 (de) |
| JP (6) | JP4834540B2 (de) |
| AT (4) | ATE465747T1 (de) |
| DE (4) | DE602004014263D1 (de) |
| WO (1) | WO2004085473A2 (de) |
Families Citing this family (73)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1608681B1 (de) * | 2003-03-28 | 2008-06-04 | FUJIFILM Manufacturing Europe B.V. | Rgd-angereicherte gelatine-ähnliche proteine mit verstärkter zellbindung |
| WO2006107188A1 (en) | 2005-04-06 | 2006-10-12 | Fujifilm Manufacturing Europe B.V. | A non-porous film for culturing cells |
| JP5138580B2 (ja) * | 2005-04-06 | 2013-02-06 | フジフィルム マニュファクチャリング ユーロプ ビー.ブイ. | 細胞培養用非孔質フィルム |
| EP2065056B1 (de) | 2006-08-29 | 2016-09-28 | FUJIFILM Corporation | Hydrophile matrix enthaltend einer schwer wasserlöslichen verbindung und herstellungsverfahren dafür |
| EP1961414A1 (de) | 2007-02-21 | 2008-08-27 | FUJIFILM Manufacturing Europe B.V. | Rekombinante Gelatine enthaltende Zusammensetzung mit gesteuerter Freisetzung |
| EP1961411A1 (de) | 2007-02-21 | 2008-08-27 | FUJIFILM Manufacturing Europe B.V. | Zusammensetzung mit gesteuerter Freisetzung |
| US8349588B2 (en) * | 2007-02-21 | 2013-01-08 | Fujifilm Manufacturing Europe B.V. | Recombinant XRGD-enriched gelatins having high stability |
| WO2008133196A1 (ja) * | 2007-04-19 | 2008-11-06 | Fujifilm Corporation | 再生医療用材料 |
| JP2008266179A (ja) | 2007-04-19 | 2008-11-06 | Fujifilm Corp | 経肺用組成物 |
| JP2009051773A (ja) * | 2007-08-27 | 2009-03-12 | Toyobo Co Ltd | 細胞接着能を有するhsp70ファミリータンパク質 |
| EP2221334B1 (de) | 2007-11-28 | 2016-12-28 | FUJIFILM Corporation | Verfahren zur chemischen modifizierung von biopolymer und polypeptid |
| GB0724179D0 (en) * | 2007-12-11 | 2008-01-23 | Ct For Process Innovation The | Fermentation process |
| WO2009075329A1 (ja) * | 2007-12-11 | 2009-06-18 | Fujifilm Corporation | 分解性を調整したゼラチン組成物 |
| US20110106243A1 (en) * | 2008-07-04 | 2011-05-05 | Elisabeth Marianna Wilhelmina Maria Van Dongen | Coating Method for Medical Devices |
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| FR2936247B1 (fr) * | 2008-09-24 | 2010-10-22 | Ct Hospitalier Universitaire De Dijon | Proteines recombinantes a activite hemostatique capables d'induire l'agregation plaquettaire. |
| US8263133B2 (en) * | 2009-02-18 | 2012-09-11 | The Regents Of The University Of California | Multivalent clustering targeting strategy for drug carriers |
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| KR102141537B1 (ko) * | 2019-03-11 | 2020-08-06 | 재단법인대구경북과학기술원 | 신경 줄기세포의 구형배양 방법 |
| WO2021020268A1 (ja) | 2019-07-26 | 2021-02-04 | 富士フイルム株式会社 | 生体移植材料 |
| EP4019025A4 (de) | 2019-08-23 | 2022-11-30 | FUJIFILM Corporation | Zusammensetzung mit mikrokapsel und zellstruktur |
| EP4159916A4 (de) | 2020-05-25 | 2023-09-06 | FUJIFILM Corporation | Zusammensetzung, blattförmiger formkörper, kunstleder und verfahren zur herstellung eines blattförmigen formkörpers |
| JPWO2022202632A1 (de) | 2021-03-24 | 2022-09-29 | ||
| EP4299482A4 (de) | 2021-03-26 | 2024-12-25 | FUJIFILM Corporation | Pulverversorgungsvorrichtung |
| CN117043535A (zh) | 2021-03-26 | 2023-11-10 | 富士胶片株式会社 | 冷冻干燥用容器 |
| WO2022210204A1 (ja) | 2021-03-31 | 2022-10-06 | 富士フイルム株式会社 | 粉砕方法、高分子ブロック製造方法及び粉砕装置 |
| WO2023013596A1 (ja) | 2021-08-02 | 2023-02-09 | 株式会社Rainbow | 幹細胞を非凍結で保存または輸送するための方法 |
| CN113788891B (zh) * | 2021-09-15 | 2023-10-31 | 山西锦波生物医药股份有限公司 | 一种重组i型人源化胶原蛋白c1l4t及其制备方法和用途 |
| WO2023053710A1 (ja) | 2021-09-30 | 2023-04-06 | 富士フイルム株式会社 | 組織修復材キット及び組織修復方法 |
| JPWO2023188492A1 (de) | 2022-03-30 | 2023-10-05 |
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| CA1324954C (en) * | 1988-03-10 | 1993-12-07 | Erkki I. Ruoslahti | Inhibition of cell migration with synthetic peptides |
| US4994388A (en) | 1988-04-15 | 1991-02-19 | Solohill Engineering, Inc. | Collagen-coated polystyrene microcarrier beads |
| JPH04221400A (ja) * | 1990-10-26 | 1992-08-11 | Fuji Photo Film Co Ltd | ゼラチン誘導体およびその用途 |
| US5179082A (en) * | 1990-11-13 | 1993-01-12 | Merck & Co., Inc. | Method for blocking platelet adhesion to collagen |
| AU3064892A (en) * | 1991-11-07 | 1993-06-07 | University Of Southern California | Compositions and methods for preventing adhesion formation |
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| JPH06192291A (ja) | 1992-09-07 | 1994-07-12 | Nippon Steel Corp | 新規ペプチドとそれを用いた血小板凝集抑制剤及び血液凝固抑制剤 |
| DE69427363T2 (de) * | 1993-09-30 | 2002-03-14 | Nippon Steel Corp., Tokio/Tokyo | Plättchenaggregationsinhibierende peptide |
| IL114140A (en) * | 1995-06-14 | 2000-06-01 | Hadasit Med Res Service | Anti-metastatic and anti-angiogenetic pharmaceutical compositions |
| EP0950098B1 (de) * | 1996-10-29 | 2008-09-03 | Commonwealth Scientific And Industrial Research Organisation | Stabile expression von tripelhelikalen proteinen |
| US5972332A (en) | 1997-04-16 | 1999-10-26 | The Regents Of The University Of Michigan | Wound treatment with keratinocytes on a solid support enclosed in a porous material |
| NL1007908C2 (nl) | 1997-12-24 | 1999-06-25 | Fuji Photo Film Bv | Zilverhalide-emulsies met recombinant collageen die geschikt zijn voor fotografische toediening alsmede de bereiding daarvan. |
| EP1014176B1 (de) | 1998-12-23 | 2009-04-29 | FUJIFILM Manufacturing Europe B.V. | Silberhalogenidemulsionen, die rekombinante gelatineartige Proteine enthalten |
| HK1046016B (en) * | 1999-11-12 | 2009-02-27 | Fibrogen, Inc. | Recombinant gelatin in vaccines |
| US6992172B1 (en) * | 1999-11-12 | 2006-01-31 | Fibrogen, Inc. | Recombinant gelatins |
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| AUPR311601A0 (en) | 2001-02-15 | 2001-03-08 | Adp Pharmaceutical Pty Limited | Matrix gene expression in chondrogenesis |
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| EP1608681B1 (de) * | 2003-03-28 | 2008-06-04 | FUJIFILM Manufacturing Europe B.V. | Rgd-angereicherte gelatine-ähnliche proteine mit verstärkter zellbindung |
| WO2013004646A1 (en) | 2011-07-05 | 2013-01-10 | Unilever N.V. | Laminate for packaging |
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