ATE461713T1 - Zusammensetzungen für die radioimmuntherapie von gehirn-tumoren - Google Patents
Zusammensetzungen für die radioimmuntherapie von gehirn-tumorenInfo
- Publication number
- ATE461713T1 ATE461713T1 AT03730342T AT03730342T ATE461713T1 AT E461713 T1 ATE461713 T1 AT E461713T1 AT 03730342 T AT03730342 T AT 03730342T AT 03730342 T AT03730342 T AT 03730342T AT E461713 T1 ATE461713 T1 AT E461713T1
- Authority
- AT
- Austria
- Prior art keywords
- radioimmunotherapy
- compositions
- radionuclide
- brain tumors
- carrier
- Prior art date
Links
- 208000003174 Brain Neoplasms Diseases 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title 1
- 238000011363 radioimmunotherapy Methods 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000008685 targeting Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1084—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody the antibody being a hybrid immunoglobulin
- A61K51/109—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody the antibody being a hybrid immunoglobulin immunoglobulins having two or more different antigen-binding sites or multifunctional antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38361702P | 2002-05-29 | 2002-05-29 | |
| PCT/GB2003/002334 WO2003101495A1 (en) | 2002-05-29 | 2003-05-28 | Methods and compositions for radioimmunotherapy of brain and cns tumors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE461713T1 true ATE461713T1 (de) | 2010-04-15 |
Family
ID=29711935
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03730342T ATE461713T1 (de) | 2002-05-29 | 2003-05-28 | Zusammensetzungen für die radioimmuntherapie von gehirn-tumoren |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20030235534A1 (de) |
| EP (1) | EP1507562B1 (de) |
| JP (1) | JP2005532343A (de) |
| AT (1) | ATE461713T1 (de) |
| AU (1) | AU2003241024A1 (de) |
| CA (1) | CA2487692A1 (de) |
| DE (1) | DE60331827D1 (de) |
| WO (1) | WO2003101495A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7521531B2 (en) * | 1996-08-28 | 2009-04-21 | Immunomedics, Inc. | Methods for the purification of stable radioiodine conjugates |
| US7405320B2 (en) | 1998-06-22 | 2008-07-29 | Immunomedics, Inc. | Therapeutic and diagnostic conjugates for use with multispecific antibodies |
| AU2004268932B2 (en) | 2003-06-13 | 2010-06-24 | Immunomedics, Inc. | D-amino acid peptides |
| US20100068151A1 (en) * | 2008-03-11 | 2010-03-18 | Rosenblum Michael G | Multimodality molecular imaging with therapeutic conjugates |
| RU2012100765A (ru) | 2009-06-12 | 2013-07-20 | Селлектар, Инк. | Эфирные и алкильные фосфолипидные производные для лечения рака и визуализации и детектирования раковых стволовых клеток |
| HRP20180293T1 (hr) | 2010-02-10 | 2018-03-23 | Fujifilm Ri Pharma Co., Ltd. | Anti-kadherin antitijelo obilježeno radioaktivnim metalom |
| US9844598B2 (en) | 2011-12-13 | 2017-12-19 | Engeneic Molecular Delivery Pty Ltd | Bacterially derived, intact minicells for delivery of therapeutic agents to brain tumors |
| JP6872181B2 (ja) | 2015-05-20 | 2021-05-19 | 国立大学法人 鹿児島大学 | ＩｇＧ結合ペプチドによる抗体の特異的修飾 |
| PL3470418T3 (pl) | 2016-06-13 | 2024-12-16 | Kagoshima University | Przeciwciało znakowane izotopem promieniotwórczym specyficzne dla danego miejsca wykorzystujące peptyd wiążący IgG |
| CN112805036A (zh) * | 2018-07-31 | 2021-05-14 | 第一三共株式会社 | 通过施用抗体-药物缀合物对转移性脑肿瘤的治疗 |
| MX2023002887A (es) * | 2020-09-10 | 2023-08-16 | Mustang Bio Inc | Terapia combinada que comprende células t del receptor de antígenos quiméricos (car) dirigidas al cáncer y un método para utilizar las mismas para un tratamiento para el cáncer. |
| WO2022167052A1 (en) | 2021-02-08 | 2022-08-11 | Y-Mabs Therapeutics, Inc. | Use of ascorbic acid as stabilizing agent for anti b7-h3 antibodies |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4348376A (en) * | 1980-03-03 | 1982-09-07 | Goldenberg Milton David | Tumor localization and therapy with labeled anti-CEA antibody |
| US4818706A (en) * | 1983-04-19 | 1989-04-04 | American Monitor Corporation | Reagent-dispensing system and method |
| US4732864A (en) * | 1983-10-06 | 1988-03-22 | E. I. Du Pont De Nemours And Company | Trace-labeled conjugates of metallothionein and target-seeking biologically active molecules |
| US4824659A (en) * | 1985-06-07 | 1989-04-25 | Immunomedics, Inc. | Antibody conjugates |
| FR2604092B1 (fr) * | 1986-09-19 | 1990-04-13 | Immunotech Sa | Immunoreactifs destines a cibler les cellules animales pour leur visualisation ou leur destruction in vivo |
| US5019368A (en) * | 1989-02-23 | 1991-05-28 | Cancer Biologics, Inc. | Detection of necrotic malignant tissue and associated therapy |
| US4900684A (en) * | 1987-06-01 | 1990-02-13 | Immunomedics, Inc. | CEA immunoassay free of human anti-mouse antibody false positives |
| US5612016A (en) * | 1988-04-01 | 1997-03-18 | Immunomedics, Inc. | Conjugates of antibodies and bifunctional ligands |
| US5460785A (en) * | 1989-08-09 | 1995-10-24 | Rhomed Incorporated | Direct labeling of antibodies and other protein with metal ions |
| WO1993017715A1 (en) * | 1992-03-05 | 1993-09-16 | Board Of Regents, The University Of Texas System | Diagnostic and/or therapeutic agents, targeted to neovascular endothelial cells |
| US5965132A (en) * | 1992-03-05 | 1999-10-12 | Board Of Regents, The University Of Texas System | Methods and compositions for targeting the vasculature of solid tumors |
| DE69332952T2 (de) * | 1992-09-04 | 2004-02-19 | The General Hospital Corp., Boston | Diagnostische und therapeutische Einheiten enthaltende biokompatible Polymere |
| US5998222A (en) * | 1993-11-29 | 1999-12-07 | Utah State University | Reconditioning antibiotic-adulterated milk products |
| WO1995026206A1 (en) * | 1994-03-28 | 1995-10-05 | The Regents Of The University Of California | Method for preparing radionuclide-labeled chelating agent-ligand complexes |
| US5874540A (en) * | 1994-10-05 | 1999-02-23 | Immunomedics, Inc. | CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies |
| ES2297862T3 (es) * | 1996-07-12 | 2008-05-01 | Immunomedics, Inc. | Analogos de peptidos que se unen a radiometales. |
| US6183744B1 (en) * | 1997-03-24 | 2001-02-06 | Immunomedics, Inc. | Immunotherapy of B-cell malignancies using anti-CD22 antibodies |
| US6306393B1 (en) * | 1997-03-24 | 2001-10-23 | Immunomedics, Inc. | Immunotherapy of B-cell malignancies using anti-CD22 antibodies |
| WO1999066951A2 (en) * | 1998-06-22 | 1999-12-29 | Immunomedics, Inc. | Use of bi-specific antibodies for pre-targeting diagnosis and therapy |
| WO2000064946A2 (en) * | 1999-04-28 | 2000-11-02 | Board Of Regents, The University Of Texas System | Compositions and methods for cancer treatment by selectively inhibiting vegf |
| US7011816B2 (en) * | 2001-12-26 | 2006-03-14 | Immunomedics, Inc. | Labeling targeting agents with gallium-68 and gallium-67 |
-
2003
- 2003-05-28 WO PCT/GB2003/002334 patent/WO2003101495A1/en not_active Ceased
- 2003-05-28 JP JP2004508849A patent/JP2005532343A/ja active Pending
- 2003-05-28 DE DE60331827T patent/DE60331827D1/de not_active Expired - Lifetime
- 2003-05-28 AU AU2003241024A patent/AU2003241024A1/en not_active Abandoned
- 2003-05-28 CA CA002487692A patent/CA2487692A1/en not_active Abandoned
- 2003-05-28 AT AT03730342T patent/ATE461713T1/de not_active IP Right Cessation
- 2003-05-28 EP EP03730342A patent/EP1507562B1/de not_active Expired - Lifetime
- 2003-05-29 US US10/447,266 patent/US20030235534A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1507562A1 (de) | 2005-02-23 |
| WO2003101495A1 (en) | 2003-12-11 |
| CA2487692A1 (en) | 2003-12-11 |
| DE60331827D1 (de) | 2010-05-06 |
| AU2003241024A1 (en) | 2003-12-19 |
| JP2005532343A (ja) | 2005-10-27 |
| EP1507562B1 (de) | 2010-03-24 |
| US20030235534A1 (en) | 2003-12-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |