ATE451108T1 - Verfahren zur behandlung von verletzungen des nervensystems in verbindung mit einer blutung - Google Patents

Verfahren zur behandlung von verletzungen des nervensystems in verbindung mit einer blutung

Info

Publication number: ATE451108T1
Authority: AT; Austria
Prior art keywords: nervous system; hemorrhage; system injuries; injuries associated; treating nervous
Prior art date: 2002-11-07

Application number

AT03759773T

Other languages

German (de)

English (en)

Inventor

Clifford Steer

Walter Low

Cecilia Rodriguez

Zhenhong Nan

Original Assignee

Univ Minnesota

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-11-07

Filing date

2003-10-08

Publication date

2009-12-15

2003-10-08 Application filed by Univ Minnesota filed Critical Univ Minnesota

2009-12-15 Application granted granted Critical

2009-12-15 Publication of ATE451108T1 publication Critical patent/ATE451108T1/de

Links

208000032843 Hemorrhage Diseases 0.000 title 1
208000001738 Nervous System Trauma Diseases 0.000 title 1
RUDATBOHQWOJDD-UHFFFAOYSA-N (3beta,5beta,7alpha)-3,7-Dihydroxycholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)CC2 RUDATBOHQWOJDD-UHFFFAOYSA-N 0.000 abstract 2
RUDATBOHQWOJDD-UZVSRGJWSA-N ursodeoxycholic acid Chemical compound C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-UZVSRGJWSA-N 0.000 abstract 2
229960001661 ursodiol Drugs 0.000 abstract 2
HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 abstract 1
BHTRKEVKTKCXOH-UHFFFAOYSA-N Taurochenodesoxycholsaeure Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(=O)NCCS(O)(=O)=O)C)C1(C)CC2 BHTRKEVKTKCXOH-UHFFFAOYSA-N 0.000 abstract 1
239000003613 bile acid Substances 0.000 abstract 1
230000006378 damage Effects 0.000 abstract 1
210000000653 nervous system Anatomy 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
BHTRKEVKTKCXOH-LBSADWJPSA-N tauroursodeoxycholic acid Chemical compound C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(=O)NCCS(O)(=O)=O)C)[C@@]2(C)CC1 BHTRKEVKTKCXOH-LBSADWJPSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Diabetes (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Medicinal Preparation (AREA)

AT03759773T 2002-11-07 2003-10-08 Verfahren zur behandlung von verletzungen des nervensystems in verbindung mit einer blutung ATE451108T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US42521002P	2002-11-07	2002-11-07
US45161503P	2003-03-03	2003-03-03
PCT/US2003/031989 WO2004043342A2 (fr)	2002-11-07	2003-10-08	Methodes permettant de traiter de blessures du systeme nerveux associees a une hemorragie

Publications (1)

Publication Number	Publication Date
ATE451108T1 true ATE451108T1 (de)	2009-12-15

Family

ID=32314576

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03759773T ATE451108T1 (de)	2002-11-07	2003-10-08	Verfahren zur behandlung von verletzungen des nervensystems in verbindung mit einer blutung

Country Status (8)

Country	Link
US (1)	US20060135494A1 (fr)
EP (1)	EP1575578B1 (fr)
JP (1)	JP2006510740A (fr)
KR (1)	KR20050103185A (fr)
AT (1)	ATE451108T1 (fr)
AU (1)	AU2003275495A1 (fr)
DE (1)	DE60330501D1 (fr)
WO (1)	WO2004043342A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7772220B2 (en)	2004-10-15	2010-08-10	Seo Hong Yoo	Methods and compositions for reducing toxicity of a pharmaceutical compound
US20030044413A1 (en) *	2000-08-15	2003-03-06	Regents Of The University Of Minnesota	Methods of limiting apoptosis of cells
US20060204481A1 (en) *	2003-04-02	2006-09-14	Steer Clifford J	Methods of promoting cell viability
CN101035541B (zh) *	2004-08-30	2012-05-30	柳署弘	溶解的udca在局灶缺血模型中的神经保护作用
AU2005295541B2 (en)	2004-10-15	2011-02-17	Seo Hong Yoo	Methods and compositions for reducing toxicity of a pharmaceutical compound
US20080194531A1 (en) *	2005-02-10	2008-08-14	Steer Clifford J	Methods for Treating Visual Disorders
CN101534641A (zh) *	2006-03-22	2009-09-16	哈佛大学校长及研究员协会	治疗高胆固醇血症和动脉粥样硬化的方法和组合物
KR20180029317A (ko) *	2016-09-12	2018-03-21	경상대학교산학협력단	간손상 예방, 개선 또는 치료용 조성물
KR101953298B1 (ko) *	2017-07-18	2019-02-28	의료법인 성광의료재단	우르소데옥시콜산을 함유하는 염증성 질환 또는 척수 손상 예방 또는 치료용 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2090876A1 (fr) *	1991-07-03	1993-01-04	Satoru Nakai	Composition regulatrice d'apoptose
US5656725A (en) *	1995-05-12	1997-08-12	Apoptosis Technology, Inc.	Peptides and compositions which modulate apoptosis
US6544972B1 (en) *	1997-09-25	2003-04-08	Regents Of The University Of Minnesota	Methods of limiting apoptosis of cells
US6555141B1 (en) *	1998-02-27	2003-04-29	Nutramax Laboratories, Inc.	L-ergothioneine, Milk thistle, and S-adenosylmethionine for the prevention, treatment and repair of liver damage
GB0019290D0 (en) *	2000-08-04	2000-09-27	Symphar Sa	Methods for inducing apolipoprotein E secretion
US20030044413A1 (en) *	2000-08-15	2003-03-06	Regents Of The University Of Minnesota	Methods of limiting apoptosis of cells

2003
- 2003-10-08 JP JP2005507039A patent/JP2006510740A/ja active Pending
- 2003-10-08 WO PCT/US2003/031989 patent/WO2004043342A2/fr not_active Ceased
- 2003-10-08 DE DE60330501T patent/DE60330501D1/de not_active Expired - Lifetime
- 2003-10-08 AT AT03759773T patent/ATE451108T1/de not_active IP Right Cessation
- 2003-10-08 AU AU2003275495A patent/AU2003275495A1/en not_active Abandoned
- 2003-10-08 KR KR1020057008192A patent/KR20050103185A/ko not_active Withdrawn
- 2003-10-08 US US10/532,039 patent/US20060135494A1/en not_active Abandoned
- 2003-10-08 EP EP03759773A patent/EP1575578B1/fr not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP1575578A4 (fr)	2007-10-10
JP2006510740A (ja)	2006-03-30
DE60330501D1 (de)	2010-01-21
EP1575578B1 (fr)	2009-12-09
US20060135494A1 (en)	2006-06-22
WO2004043342A3 (fr)	2004-07-15
AU2003275495A8 (en)	2004-06-03
WO2004043342A2 (fr)	2004-05-27
HK1086479A1 (zh)	2006-09-22
EP1575578A2 (fr)	2005-09-21
AU2003275495A1 (en)	2004-06-03
KR20050103185A (ko)	2005-10-27

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Legal Events

Date	Code	Title	Description
2010-06-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties