ATE311378T1 - Benzopyran derivate - Google Patents
Benzopyran derivateInfo
- Publication number
- ATE311378T1 ATE311378T1 AT00961032T AT00961032T ATE311378T1 AT E311378 T1 ATE311378 T1 AT E311378T1 AT 00961032 T AT00961032 T AT 00961032T AT 00961032 T AT00961032 T AT 00961032T AT E311378 T1 ATE311378 T1 AT E311378T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- hydrogen atom
- alkyl group
- substituted
- absent
- Prior art date
Links
- 150000001562 benzopyrans Chemical class 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 5
- 150000003839 salts Chemical class 0.000 abstract 2
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- -1 (substituted)phenyl group Chemical group 0.000 abstract 1
- KYNSBQPICQTCGU-UHFFFAOYSA-N Benzopyrane Chemical compound C1=CC=C2C=CCOC2=C1 KYNSBQPICQTCGU-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000005196 alkyl carbonyloxy group Chemical group 0.000 abstract 1
- 239000003416 antiarrhythmic agent Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000036747 functional refractory period Effects 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP26445599 | 1999-09-17 | ||
| PCT/JP2000/006323 WO2001021610A1 (en) | 1999-09-17 | 2000-09-14 | Benzopyran derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE311378T1 true ATE311378T1 (de) | 2005-12-15 |
Family
ID=17403453
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00961032T ATE311378T1 (de) | 1999-09-17 | 2000-09-14 | Benzopyran derivate |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6589983B1 (de) |
| EP (1) | EP1212314B1 (de) |
| KR (1) | KR100766676B1 (de) |
| CN (1) | CN1167697C (de) |
| AT (1) | ATE311378T1 (de) |
| AU (1) | AU766935B2 (de) |
| CA (1) | CA2383583C (de) |
| CZ (1) | CZ2002802A3 (de) |
| DE (1) | DE60024471T2 (de) |
| HK (1) | HK1047106B (de) |
| HU (1) | HUP0202690A3 (de) |
| IL (2) | IL147968A0 (de) |
| NO (1) | NO328013B1 (de) |
| NZ (1) | NZ517404A (de) |
| RU (1) | RU2234502C2 (de) |
| SK (1) | SK3292002A3 (de) |
| WO (1) | WO2001021610A1 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW589305B (en) * | 2001-02-14 | 2004-06-01 | Nissan Chemical Ind Ltd | 4-aminobenzopyran derivatives |
| FI20011507A0 (fi) | 2001-07-10 | 2001-07-10 | Orion Corp | Uusia yhdisteitä |
| JP2005505586A (ja) * | 2001-10-04 | 2005-02-24 | ワイス | ５−ヒドロキシトリプタミン−６リガンドとしてのクロマン誘導体 |
| RU2314302C2 (ru) * | 2002-08-29 | 2008-01-10 | Ниссан Кемикал Индастриз, ЛТД | Способ получения производного аминобензопирана |
| FI20030030A0 (fi) * | 2003-01-09 | 2003-01-09 | Orion Corp | Uusia yhdisteitä |
| GB0315950D0 (en) | 2003-06-11 | 2003-08-13 | Xention Discovery Ltd | Compounds |
| TWI346112B (en) | 2004-02-25 | 2011-08-01 | Nissan Chemical Ind Ltd | Benzopyran compound |
| AU2005223612B2 (en) | 2004-03-23 | 2010-06-24 | Nissan Chemical Industries, Ltd. | Tricyclic benzopyran compound as anti-arrhythmic agents |
| GB0412986D0 (en) | 2004-06-10 | 2004-07-14 | Xention Discovery Ltd | Compounds |
| US7576212B2 (en) | 2004-12-09 | 2009-08-18 | Xention Limited | Thieno[2,3-B] pyridines as potassium channel inhibitors |
| BRPI0515830A (pt) * | 2004-12-21 | 2008-08-05 | F Hoffmann La Roche | derivados de cromano e usos dos mesmos no tratamento de distúrbios do sistema nervoso central |
| GB0525164D0 (en) | 2005-12-09 | 2006-01-18 | Xention Discovery Ltd | Compounds |
| WO2007105658A1 (ja) * | 2006-03-10 | 2007-09-20 | Nissan Chemical Industries, Ltd. | 光学活性クロメンオキシド化合物の製造方法 |
| GB0815782D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| GB0815781D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| GB0815784D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| AU2011274369A1 (en) * | 2010-07-02 | 2012-12-06 | Ventana Medical Systems, Inc. | Hapten conjugates for target detection |
| GB201105659D0 (en) | 2011-04-01 | 2011-05-18 | Xention Ltd | Compounds |
| NO3175985T3 (de) | 2011-07-01 | 2018-04-28 | ||
| WO2013072693A1 (en) | 2011-11-15 | 2013-05-23 | Xention Limited | Thieno [2, 3 - c] pyrazoles for use as potassium channel inhibitors |
| AR090037A1 (es) | 2011-11-15 | 2014-10-15 | Xention Ltd | Derivados de tieno y/o furo-pirimidinas y piridinas inhibidores de los canales de potasio |
| HK1201455A1 (en) | 2012-01-27 | 2015-09-04 | Gilead Sciences Inc | Combination therapies using late sodium ion channel blockers and potassium ion channel blockers |
| JP7468869B2 (ja) | 2018-12-28 | 2024-04-16 | 国立大学法人大阪大学 | 遺伝性徐脈性不整脈治療薬 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9005318D0 (en) | 1990-03-09 | 1990-05-02 | Isis Innovation | Antiarrhythmic agents |
| AU651105B2 (en) * | 1990-06-18 | 1994-07-14 | E.R. Squibb & Sons, Inc. | Benzopyran derivatives and heterocyclic analogs thereof as antiischemic agents |
| GB9301611D0 (en) * | 1993-08-04 | 1993-08-04 | Parisella Gerald | Dexterity game |
| SK7599A3 (en) | 1996-07-26 | 1999-07-12 | Nissan Chemical Ind Ltd | Chroman derivatives and pharmaceutical composition containing the same |
-
2000
- 2000-09-14 CN CNB008129509A patent/CN1167697C/zh not_active Expired - Fee Related
- 2000-09-14 WO PCT/JP2000/006323 patent/WO2001021610A1/en not_active Ceased
- 2000-09-14 CA CA002383583A patent/CA2383583C/en not_active Expired - Fee Related
- 2000-09-14 IL IL14796800A patent/IL147968A0/xx active IP Right Grant
- 2000-09-14 HK HK02108750.1A patent/HK1047106B/en not_active IP Right Cessation
- 2000-09-14 CZ CZ2002802A patent/CZ2002802A3/cs unknown
- 2000-09-14 SK SK329-2002A patent/SK3292002A3/sk unknown
- 2000-09-14 KR KR1020027003510A patent/KR100766676B1/ko not_active Expired - Fee Related
- 2000-09-14 AU AU73143/00A patent/AU766935B2/en not_active Ceased
- 2000-09-14 RU RU2002110115/04A patent/RU2234502C2/ru not_active IP Right Cessation
- 2000-09-14 AT AT00961032T patent/ATE311378T1/de not_active IP Right Cessation
- 2000-09-14 EP EP00961032A patent/EP1212314B1/de not_active Expired - Lifetime
- 2000-09-14 US US10/048,026 patent/US6589983B1/en not_active Expired - Fee Related
- 2000-09-14 DE DE60024471T patent/DE60024471T2/de not_active Expired - Lifetime
- 2000-09-14 HU HU0202690A patent/HUP0202690A3/hu unknown
- 2000-09-14 NZ NZ517404A patent/NZ517404A/xx unknown
-
2002
- 2002-02-03 IL IL147968A patent/IL147968A/en not_active IP Right Cessation
- 2002-03-15 NO NO20021294A patent/NO328013B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CZ2002802A3 (cs) | 2003-02-12 |
| DE60024471T2 (de) | 2006-08-03 |
| HK1047106B (en) | 2006-04-28 |
| CA2383583C (en) | 2009-04-07 |
| IL147968A (en) | 2006-04-10 |
| AU7314300A (en) | 2001-04-24 |
| SK3292002A3 (en) | 2003-04-01 |
| NO20021294L (no) | 2002-03-15 |
| KR20020068505A (ko) | 2002-08-27 |
| WO2001021610A1 (en) | 2001-03-29 |
| AU766935B2 (en) | 2003-10-23 |
| NO328013B1 (no) | 2009-11-09 |
| CA2383583A1 (en) | 2001-03-29 |
| CN1374957A (zh) | 2002-10-16 |
| DE60024471D1 (de) | 2006-01-05 |
| US6589983B1 (en) | 2003-07-08 |
| RU2234502C2 (ru) | 2004-08-20 |
| EP1212314B1 (de) | 2005-11-30 |
| HUP0202690A3 (en) | 2005-02-28 |
| IL147968A0 (en) | 2002-09-12 |
| KR100766676B1 (ko) | 2007-10-15 |
| CN1167697C (zh) | 2004-09-22 |
| HUP0202690A2 (hu) | 2002-12-28 |
| EP1212314A1 (de) | 2002-06-12 |
| HK1047106A1 (en) | 2003-02-07 |
| NO20021294D0 (no) | 2002-03-15 |
| NZ517404A (en) | 2003-01-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |