ATE397012T1 - Therapeutische verwendung von verdünnten surfactants zur lungenwaschung - Google Patents
Therapeutische verwendung von verdünnten surfactants zur lungenwaschungInfo
- Publication number
- ATE397012T1 ATE397012T1 AT98906033T AT98906033T ATE397012T1 AT E397012 T1 ATE397012 T1 AT E397012T1 AT 98906033 T AT98906033 T AT 98906033T AT 98906033 T AT98906033 T AT 98906033T AT E397012 T1 ATE397012 T1 AT E397012T1
- Authority
- AT
- Austria
- Prior art keywords
- therapeutic use
- surfactant
- variety
- disclosed
- molecules
- Prior art date
Links
- 239000004094 surface-active agent Substances 0.000 title abstract 5
- 210000004072 lung Anatomy 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 238000005406 washing Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 206010001052 Acute respiratory distress syndrome Diseases 0.000 abstract 1
- 201000005085 Meconium Aspiration Syndrome Diseases 0.000 abstract 1
- 208000013616 Respiratory Distress Syndrome Diseases 0.000 abstract 1
- 210000000416 exudates and transudate Anatomy 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000002685 pulmonary effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pulmonology (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Marine Sciences & Fisheries (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/848,580 US6013619A (en) | 1988-01-06 | 1997-04-28 | Pulmonary surfactants and therapeutic uses, including pulmonary lavage |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE397012T1 true ATE397012T1 (de) | 2008-06-15 |
Family
ID=25303699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98906033T ATE397012T1 (de) | 1997-04-28 | 1998-01-29 | Therapeutische verwendung von verdünnten surfactants zur lungenwaschung |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6013619A (de) |
| EP (1) | EP1005485B1 (de) |
| JP (2) | JPH10316587A (de) |
| AT (1) | ATE397012T1 (de) |
| AU (1) | AU734991B2 (de) |
| BR (1) | BR9809321A (de) |
| CA (1) | CA2288375C (de) |
| DE (1) | DE69839558D1 (de) |
| NZ (2) | NZ337619A (de) |
| WO (1) | WO1998049191A1 (de) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6613734B2 (en) * | 1988-01-06 | 2003-09-02 | The Scripps Research Institute | Peptides-containing liposomal surfactants |
| ES2189269T3 (es) * | 1997-12-03 | 2003-07-01 | Britannia Pharmaceuticals Ltd | Mejoras en medicamentos para el tratamiento del asma. |
| US20030221199A1 (en) * | 1998-10-20 | 2003-11-27 | Whitsett Jeffrey A. | Surfactant protein D for the prevention and diagnosis of pulmonary emphysema |
| US6838428B2 (en) * | 1998-10-20 | 2005-01-04 | Children's Hospital Medical Center | Surfactant protein D for the prevention and diagnosis of pulmonary emphysema |
| US8933032B2 (en) | 1998-10-20 | 2015-01-13 | Children's Hospital Medical Center | Surfactant protein D for the treatment of disorders associated with lung injury |
| DE19858463A1 (de) * | 1998-12-18 | 2000-06-21 | Centeon Pharma Gmbh | Verwendung eines Fibrinklebers zur Regeneration des Lebergewebes |
| WO2000076535A1 (en) * | 1999-06-11 | 2000-12-21 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Pharmaceutical preparation containing modifications of surfactant protein b (sp-b) and surfactant protein c (sp-c) |
| US6287290B1 (en) | 1999-07-02 | 2001-09-11 | Pulmonx | Methods, systems, and kits for lung volume reduction |
| AU6083899A (en) | 1999-09-16 | 2001-04-17 | Aventis Behring Gmbh | Combination of c1-inh and lung surfactant for the treatment of respiratory disorders |
| AU2003201A (en) * | 1999-12-01 | 2001-06-12 | Byk Gulden Lomberg Chemische Fabrik Gmbh | Novel use of lung surfactant |
| JP2003530356A (ja) * | 2000-04-12 | 2003-10-14 | アルタナ ファルマ アクチエンゲゼルシャフト | 急性肺疾患の予防又は早期治療のための肺表面活性物質の新規使用 |
| US6527761B1 (en) | 2000-10-27 | 2003-03-04 | Pulmonx, Inc. | Methods and devices for obstructing and aspirating lung tissue segments |
| US20030030542A1 (en) * | 2001-08-10 | 2003-02-13 | Von Hoffmann Gerard | PDA security system |
| WO2003022221A2 (en) | 2001-09-10 | 2003-03-20 | Pulmonx | Method and apparatus for endobronchial diagnosis |
| EP1435994B1 (de) | 2001-10-11 | 2010-05-19 | Nycomed GmbH | Neue verwendung von lungensurfactant |
| WO2003053455A1 (en) * | 2001-12-12 | 2003-07-03 | Penn State Research Foundation | Surfactant prevention of lung complications from cancer chemotherapy |
| US7490604B2 (en) * | 2002-03-15 | 2009-02-17 | C. R. Bard, Inc. | Endotracheal surfactant distribution system |
| NZ536796A (en) * | 2002-04-25 | 2007-03-30 | Scripps Research Inst | Treatment and prevention of pulmonary conditions comprising at least one lung surfactant polypeptide and at least one protease inhibitor, lipase inhibitor or an anti-oxidant |
| RU2005115956A (ru) * | 2002-10-25 | 2006-08-10 | Сеймур Дж. КУРТЦ (US) | Способ лечения инсулинорезистентности, диабета взрослых и метаболического синдрома х |
| US20070065433A1 (en) * | 2003-02-21 | 2007-03-22 | Mollnes Tom E | Methods and compositions for the treatment of meconium aspiration syndrome |
| AU2004296206A1 (en) * | 2003-12-04 | 2005-06-23 | The Scripps Research Institute | Treatment and preventions of asthma |
| US7464012B2 (en) * | 2004-12-10 | 2008-12-09 | L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude | Simplified process simulator |
| US8337815B2 (en) * | 2004-12-23 | 2012-12-25 | Discovery Laboratories, Inc. | Pulmonary surfactant formulations |
| SI1841458T1 (sl) | 2005-01-06 | 2012-04-30 | Discovery Lab Inc | Zdravljenje s predpisanim odmerjanjem surfaktanta za zdravljenje ali preprečevanje bronhopulmonalne displazije |
| US8496006B2 (en) | 2005-01-20 | 2013-07-30 | Pulmonx Corporation | Methods and devices for passive residual lung volume reduction and functional lung volume expansion |
| US11883029B2 (en) | 2005-01-20 | 2024-01-30 | Pulmonx Corporation | Methods and devices for passive residual lung volume reduction and functional lung volume expansion |
| US20080228137A1 (en) | 2007-03-12 | 2008-09-18 | Pulmonx | Methods and devices for passive residual lung volume reduction and functional lung volume expansion |
| CA2606688A1 (en) * | 2005-05-03 | 2006-11-09 | Ross Allen Ridsdale | Phospholipid formulations and uses thereof in lung disease detection and treatment |
| US20110177996A1 (en) * | 2005-05-23 | 2011-07-21 | Children's Hospital Medical Center | Regulatory proteins in lung repair and treatment of lung disease |
| ZA200800255B (en) * | 2005-06-24 | 2009-04-29 | Drugrecure Aps | Airway administration of activated protein C in inflammatory conditions affecting the respiratory tract |
| WO2007092939A2 (en) * | 2006-02-08 | 2007-08-16 | Morphotek, Inc. | Antigenic gm-csf peptides and antibodies to gm-csf |
| EP2063903A1 (de) * | 2006-09-19 | 2009-06-03 | Discovery Laboratories, Inc. | Lungentensidformulierungen und verfahren zur förderung von schleimbeseitigung |
| CN102014924B (zh) | 2007-06-21 | 2012-07-18 | 潘塔希生物科学股份有限公司 | 用雌激素治疗胎粪吸入综合征 |
| EP2349420B1 (de) | 2008-09-25 | 2016-08-31 | Covidien LP | Inversionsbasierte feed-forward-kompensierung der einatmungs-trigger-dynamik in medizinischen beatmungsgeräten |
| US8434479B2 (en) * | 2009-02-27 | 2013-05-07 | Covidien Lp | Flow rate compensation for transient thermal response of hot-wire anemometers |
| US20110213215A1 (en) * | 2010-02-26 | 2011-09-01 | Nellcor Puritan Bennett Llc | Spontaneous Breathing Trial Manager |
| US20120220531A1 (en) | 2011-02-04 | 2012-08-30 | Cincinnati Children's Hospital Medical Center | Surfactant protein d for the treatment of disorders associated with lung injury |
| US9089657B2 (en) | 2011-10-31 | 2015-07-28 | Covidien Lp | Methods and systems for gating user initiated increases in oxygen concentration during ventilation |
| WO2013188016A2 (en) | 2012-05-04 | 2013-12-19 | Discovery Laboratories, Inc. | Surfactant therapy for exposure to ionizing radiation |
| WO2014210030A2 (en) * | 2013-06-25 | 2014-12-31 | Ino Therapeutics Llc | Methods of reducing the risk of mortality associated with a medical treatment |
| RU2691648C1 (ru) * | 2018-05-28 | 2019-06-17 | Олег Александрович Розенберг | Способ получения сурфактанта из легких крупного рогатого скота |
| US20230257446A1 (en) | 2020-01-28 | 2023-08-17 | Chiesi Farmaceutici S.P.A. | Polypeptides having improved properties |
| CN114767977B (zh) * | 2022-04-18 | 2023-10-13 | 广州呼吸健康研究院(广州呼吸疾病研究所) | 一种针对离体肺获取的支气管肺泡灌洗液及其获取方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3369644D1 (en) * | 1982-11-22 | 1987-03-12 | Teijin Ltd | Artificial lung surfactant and remedy for respiratory distress syndrome containing it as active principle |
| US5260273A (en) * | 1988-01-06 | 1993-11-09 | The Scripps Research Institute | Pulmonary surfactant protein and related polypeptide |
| US5164369A (en) * | 1988-01-06 | 1992-11-17 | The Scripps Research Institute | Pulmonary surfactant protein and related polypeptide |
| US4861756A (en) * | 1988-03-08 | 1989-08-29 | Merrell Dow Pharmaceuticals Inc. | Synthetic pulmonary surfactant |
| US5562608A (en) * | 1989-08-28 | 1996-10-08 | Biopulmonics, Inc. | Apparatus for pulmonary delivery of drugs with simultaneous liquid lavage and ventilation |
| US5803078A (en) * | 1994-05-06 | 1998-09-08 | Brauner; Mark E. | Methods and apparatus for intrapulmonary therapy and drug administration |
-
1997
- 1997-04-28 US US08/848,580 patent/US6013619A/en not_active Expired - Lifetime
-
1998
- 1998-01-29 NZ NZ337619A patent/NZ337619A/en not_active IP Right Cessation
- 1998-01-29 AT AT98906033T patent/ATE397012T1/de not_active IP Right Cessation
- 1998-01-29 WO PCT/US1998/001711 patent/WO1998049191A1/en not_active Ceased
- 1998-01-29 BR BR9809321-5A patent/BR9809321A/pt not_active Application Discontinuation
- 1998-01-29 AU AU61369/98A patent/AU734991B2/en not_active Expired
- 1998-01-29 EP EP98906033A patent/EP1005485B1/de not_active Revoked
- 1998-01-29 NZ NZ511640A patent/NZ511640A/en not_active IP Right Cessation
- 1998-01-29 CA CA002288375A patent/CA2288375C/en not_active Expired - Lifetime
- 1998-01-29 DE DE69839558T patent/DE69839558D1/de not_active Revoked
- 1998-04-28 JP JP10118861A patent/JPH10316587A/ja active Pending
-
2004
- 2004-06-08 JP JP2004170190A patent/JP2004250459A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US6013619A (en) | 2000-01-11 |
| CA2288375C (en) | 2002-09-10 |
| EP1005485A1 (de) | 2000-06-07 |
| JP2004250459A (ja) | 2004-09-09 |
| BR9809321A (pt) | 2000-07-04 |
| NZ337619A (en) | 2001-08-31 |
| NZ511640A (en) | 2005-07-29 |
| DE69839558D1 (de) | 2008-07-10 |
| AU734991B2 (en) | 2001-06-28 |
| AU6136998A (en) | 1998-11-24 |
| WO1998049191A1 (en) | 1998-11-05 |
| CA2288375A1 (en) | 1998-11-05 |
| EP1005485B1 (de) | 2008-05-28 |
| JPH10316587A (ja) | 1998-12-02 |
| EP1005485A4 (de) | 2004-03-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |