ATE384066T1 - Thieno-pyrrole verbindungen als antagonisten der gonadotropin-freisetzenden hormonrezeptoren - Google Patents
Thieno-pyrrole verbindungen als antagonisten der gonadotropin-freisetzenden hormonrezeptorenInfo
- Publication number
- ATE384066T1 ATE384066T1 AT03748242T AT03748242T ATE384066T1 AT E384066 T1 ATE384066 T1 AT E384066T1 AT 03748242 T AT03748242 T AT 03748242T AT 03748242 T AT03748242 T AT 03748242T AT E384066 T1 ATE384066 T1 AT E384066T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- thieno
- releasing hormone
- antagonists
- gonadotropin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02292076 | 2002-08-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE384066T1 true ATE384066T1 (de) | 2008-02-15 |
Family
ID=31896981
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03748242T ATE384066T1 (de) | 2002-08-21 | 2003-08-18 | Thieno-pyrrole verbindungen als antagonisten der gonadotropin-freisetzenden hormonrezeptoren |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7317010B2 (de) |
| EP (1) | EP1532154B1 (de) |
| JP (1) | JP2006508050A (de) |
| AT (1) | ATE384066T1 (de) |
| AU (1) | AU2003267551A1 (de) |
| DE (1) | DE60318716T2 (de) |
| ES (1) | ES2298545T3 (de) |
| WO (1) | WO2004018479A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60318875T2 (de) * | 2002-06-28 | 2009-01-15 | Euro-Celtique S.A. | Therapeutische piperazin-derivate für die behandlung von schmerzen |
| TW200407127A (en) * | 2002-08-21 | 2004-05-16 | Astrazeneca Ab | Chemical compounds |
| DK1648904T3 (da) | 2003-07-31 | 2007-10-22 | Wyeth Corp | N-sulfonylheterocyclopyrrolalkylaminforbindelser som 5-hydroxytryptamin-6-ligander |
| CN1942479A (zh) * | 2004-02-20 | 2007-04-04 | 阿斯利康(瑞典)有限公司 | 用作GnRH拮抗剂的噻吩并吡咯类化合物 |
| CN1942190A (zh) * | 2004-02-20 | 2007-04-04 | 阿斯利康(瑞典)有限公司 | 用作促性腺激素释放激素(GnRH)拮抗剂的吡咯衍生物 |
| GB0403781D0 (en) * | 2004-02-20 | 2004-03-24 | Astrazeneca Ab | Chemical compounds |
| TWI350168B (en) | 2004-05-07 | 2011-10-11 | Incyte Corp | Amido compounds and their use as pharmaceuticals |
| BRPI0512535A (pt) | 2004-06-24 | 2008-03-25 | Incyte Corp | compostos de piperidinas n-substituìdas, suas composições e métodos de modulações |
| EP2227233B1 (de) | 2007-11-30 | 2013-02-13 | Newlink Genetics | Ido-inhibitoren |
| EP2739144A4 (de) * | 2011-06-20 | 2015-04-01 | Alzheimer S Inst Of America Inc | Verbindungen und ihre therapeutische verwendung |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04356029A (ja) | 1990-07-02 | 1992-12-09 | Japan Synthetic Rubber Co Ltd | 非線形光学素子 |
| JPH04179949A (ja) | 1990-11-15 | 1992-06-26 | Fuji Photo Film Co Ltd | 新規な色素形成カプラーおよび該カプラーを用いたハロゲン化銀カラー写真感光材料 |
| KR19990072123A (ko) | 1995-12-14 | 1999-09-27 | 폴락 돈나 엘. | 고나도트로핀분비호르몬의길항제및이를포함하는약제학적조성물 |
| ES2174129T3 (es) | 1995-12-14 | 2002-11-01 | Merck & Co Inc | Antagonistas de la hormona de liberacion de la gonadotropina. |
| CA2240115A1 (en) | 1995-12-14 | 1997-06-19 | Wallace T. Ashton | Antagonists of gonadotropin releasing hormone |
| SK77598A3 (en) | 1995-12-14 | 1999-01-11 | Merck & Co Inc | Nonpeptide derivatives, pharmaceutical composition containing them and their use |
| US6200957B1 (en) | 1995-12-14 | 2001-03-13 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| WO1998055479A1 (en) | 1997-06-05 | 1998-12-10 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| AU728988B2 (en) | 1997-06-05 | 2001-01-25 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| AU728811B2 (en) | 1997-06-05 | 2001-01-18 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| EP1011667A4 (de) | 1997-06-05 | 2001-03-28 | Merck & Co Inc | Antagonisten des gonadotrophin freisetzungs hormons |
| JP2002502426A (ja) | 1997-06-05 | 2002-01-22 | メルク エンド カンパニー インコーポレーテッド | ゴナドトロピン放出ホルモンの拮抗薬 |
| US6156772A (en) | 1997-06-05 | 2000-12-05 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| CA2308069A1 (en) | 1997-10-28 | 1999-05-06 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| EP1027046A4 (de) | 1997-10-28 | 2002-04-03 | Merck & Co Inc | Antagonisten des gonadotropin freisetzenden hormons |
| EP1062215A4 (de) | 1998-02-11 | 2001-03-14 | Merck & Co Inc | Antagonisten des gonadotropin freisetzenden hormons |
| EP1068195A1 (de) | 1998-02-11 | 2001-01-17 | Merck & Co., Inc. | Antagonisten des "gonadotropin releasing hormone" |
| US6025366A (en) * | 1998-04-02 | 2000-02-15 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| WO1999051595A1 (en) | 1998-04-02 | 1999-10-14 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| AU3368299A (en) | 1998-04-02 | 1999-10-25 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| EP1067930A4 (de) | 1998-04-02 | 2002-09-18 | Merck & Co Inc | Antagonisten des gonadoliberins |
| JP2002510630A (ja) | 1998-04-02 | 2002-04-09 | メルク エンド カムパニー インコーポレーテッド | 性腺刺激ホルモン放出ホルモン拮抗薬 |
| CA2326140A1 (en) | 1998-04-02 | 1999-10-14 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| CA2325995A1 (en) | 1998-04-02 | 1999-10-14 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| EP1171125A1 (de) | 1999-03-10 | 2002-01-16 | Merck & Co., Inc. | 6-azaindolverbindungen als antagonisten des gonadotropin freisetzendes hormons |
| CA2367116A1 (en) | 1999-03-10 | 2000-09-14 | Merck & Co., Inc. | 6-azaindole compounds as antagonists of gonadotropin releasing hormone |
| JP2002538205A (ja) | 1999-03-10 | 2002-11-12 | メルク エンド カムパニー インコーポレーテッド | 性腺刺激ホルモン放出ホルモン拮抗薬としての６−アザインドール化合物 |
| WO2000053181A1 (en) | 1999-03-10 | 2000-09-14 | Merck & Co., Inc. | 6-azaindole compounds as antagonists of gonadotropin releasing hormone |
| AU3514200A (en) | 1999-03-10 | 2000-09-28 | Merck & Co., Inc. | 6-azaindole compounds as antagonists of gonadotropin releasing hormone |
| AU3868500A (en) | 1999-03-10 | 2000-09-28 | Merck & Co., Inc. | 6-azaindole compounds as antagonists of gonadotropin releasing hormone |
| TWI225863B (en) * | 1999-03-24 | 2005-01-01 | Takeda Chemical Industries Ltd | Thienopyrimidine compounds, their production and use |
| WO2001070227A1 (en) | 2000-03-17 | 2001-09-27 | Merck & Co., Inc. | Antagonists of gonadotropin releasing hormone |
| SE0100566D0 (sv) | 2001-02-20 | 2001-02-20 | Astrazeneca Ab | Compounds |
| SE0101692D0 (sv) | 2001-05-14 | 2001-05-14 | Astrazeneca Ab | Compounds |
-
2003
- 2003-08-18 AU AU2003267551A patent/AU2003267551A1/en not_active Abandoned
- 2003-08-18 AT AT03748242T patent/ATE384066T1/de not_active IP Right Cessation
- 2003-08-18 ES ES03748242T patent/ES2298545T3/es not_active Expired - Lifetime
- 2003-08-18 WO PCT/GB2003/003603 patent/WO2004018479A1/en not_active Ceased
- 2003-08-18 EP EP03748242A patent/EP1532154B1/de not_active Expired - Lifetime
- 2003-08-18 DE DE60318716T patent/DE60318716T2/de not_active Expired - Fee Related
- 2003-08-18 JP JP2004530353A patent/JP2006508050A/ja active Pending
- 2003-08-18 US US10/525,109 patent/US7317010B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE60318716T2 (de) | 2009-01-08 |
| ES2298545T3 (es) | 2008-05-16 |
| EP1532154A1 (de) | 2005-05-25 |
| AU2003267551A1 (en) | 2004-03-11 |
| EP1532154B1 (de) | 2008-01-16 |
| US20060004053A1 (en) | 2006-01-05 |
| WO2004018479A1 (en) | 2004-03-04 |
| US7317010B2 (en) | 2008-01-08 |
| JP2006508050A (ja) | 2006-03-09 |
| DE60318716D1 (de) | 2008-03-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |