ATE378360T1 - Polymere 3,5-dimethyl-1-adamantylammoniumsalze und deren verwendung in form von virustatika - Google Patents
Polymere 3,5-dimethyl-1-adamantylammoniumsalze und deren verwendung in form von virustatikaInfo
- Publication number
- ATE378360T1 ATE378360T1 AT03811282T AT03811282T ATE378360T1 AT E378360 T1 ATE378360 T1 AT E378360T1 AT 03811282 T AT03811282 T AT 03811282T AT 03811282 T AT03811282 T AT 03811282T AT E378360 T1 ATE378360 T1 AT E378360T1
- Authority
- AT
- Austria
- Prior art keywords
- salts
- copolymer
- acid
- adamantylammonium
- dimethyl
- Prior art date
Links
- BUGYDGFZZOZRHP-UHFFFAOYSA-N memantine Chemical class C1C(C2)CC3(C)CC1(C)CC2(N)C3 BUGYDGFZZOZRHP-UHFFFAOYSA-N 0.000 title 1
- 239000002544 virustatic Substances 0.000 title 1
- 229920001577 copolymer Polymers 0.000 abstract 9
- 150000003839 salts Chemical class 0.000 abstract 5
- DUCJNKWNTVBRKF-UHFFFAOYSA-N 2-(ethenylamino)butanedioic acid Chemical compound OC(=O)CC(C(O)=O)NC=C DUCJNKWNTVBRKF-UHFFFAOYSA-N 0.000 abstract 3
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 abstract 3
- 230000000840 anti-viral effect Effects 0.000 abstract 3
- 230000015572 biosynthetic process Effects 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 238000003786 synthesis reaction Methods 0.000 abstract 3
- 238000004458 analytical method Methods 0.000 abstract 2
- FPYJFEHAWHCUMM-UHFFFAOYSA-N maleic anhydride Chemical compound O=C1OC(=O)C=C1 FPYJFEHAWHCUMM-UHFFFAOYSA-N 0.000 abstract 2
- DAFGMHXAOXNXIM-UHFFFAOYSA-N 1-(ethenylamino)pyrrolidine-2,5-dione Chemical compound C=CNN1C(=O)CCC1=O DAFGMHXAOXNXIM-UHFFFAOYSA-N 0.000 abstract 1
- IMROMDMJAWUWLK-UHFFFAOYSA-N Ethenol Chemical compound OC=C IMROMDMJAWUWLK-UHFFFAOYSA-N 0.000 abstract 1
- 229920002125 Sokalan® Polymers 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 229940124977 antiviral medication Drugs 0.000 abstract 1
- 230000000052 comparative effect Effects 0.000 abstract 1
- LDHQCZJRKDOVOX-NSCUHMNNSA-N crotonic acid Chemical compound C\C=C\C(O)=O LDHQCZJRKDOVOX-NSCUHMNNSA-N 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 206010022000 influenza Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000004584 polyacrylic acid Substances 0.000 abstract 1
- 238000003918 potentiometric titration Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 238000001308 synthesis method Methods 0.000 abstract 1
- 230000001988 toxicity Effects 0.000 abstract 1
- 231100000419 toxicity Toxicity 0.000 abstract 1
- LDHQCZJRKDOVOX-UHFFFAOYSA-N trans-crotonic acid Natural products CC=CC(O)=O LDHQCZJRKDOVOX-UHFFFAOYSA-N 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/44—Preparation of metal salts or ammonium salts
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Polymers & Plastics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/RU2003/000417 WO2005028528A1 (en) | 2003-09-23 | 2003-09-23 | 3,5-dimethyl-1-adamantyl-ammonium polymeric salts and the use thereof in the form of antiviral agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE378360T1 true ATE378360T1 (de) | 2007-11-15 |
Family
ID=34374498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03811282T ATE378360T1 (de) | 2003-09-23 | 2003-09-23 | Polymere 3,5-dimethyl-1-adamantylammoniumsalze und deren verwendung in form von virustatika |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1669379B1 (de) |
| AT (1) | ATE378360T1 (de) |
| AU (1) | AU2003302479A1 (de) |
| DE (1) | DE60317579T2 (de) |
| EA (1) | EA200600427A1 (de) |
| WO (1) | WO2005028528A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA79908C2 (en) * | 2004-06-24 | 2007-07-25 | Olainfarm Joint Stock Company | Application of polymeric salts 3,5-dimethyl-1-adamantilammonium as immunostimulative and interferonogenous agent |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5556619A (en) * | 1992-08-20 | 1996-09-17 | The Du Pont Merck Pharmaceutical Company | Crosslinked polymeric ammonium salts |
| RU2071323C1 (ru) * | 1994-09-30 | 1997-01-10 | Санкт-Петербургский государственный технологический институт (технический университет) | Противовирусный препарат "полирем" |
| JP4838437B2 (ja) * | 2000-06-16 | 2011-12-14 | Ｊｓｒ株式会社 | 感放射線性樹脂組成物 |
| US6387383B1 (en) * | 2000-08-03 | 2002-05-14 | Dow Pharmaceutical Sciences | Topical low-viscosity gel composition |
-
2003
- 2003-09-23 AU AU2003302479A patent/AU2003302479A1/en not_active Abandoned
- 2003-09-23 AT AT03811282T patent/ATE378360T1/de not_active IP Right Cessation
- 2003-09-23 DE DE60317579T patent/DE60317579T2/de not_active Expired - Lifetime
- 2003-09-23 EA EA200600427A patent/EA200600427A1/ru unknown
- 2003-09-23 WO PCT/RU2003/000417 patent/WO2005028528A1/ru not_active Ceased
- 2003-09-23 EP EP03811282A patent/EP1669379B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1669379B1 (de) | 2007-11-14 |
| EP1669379A1 (de) | 2006-06-14 |
| AU2003302479A1 (en) | 2005-04-11 |
| DE60317579T2 (de) | 2008-09-18 |
| WO2005028528A1 (en) | 2005-03-31 |
| EP1669379A4 (de) | 2006-11-08 |
| EA200600427A1 (ru) | 2006-12-29 |
| DE60317579D1 (de) | 2007-12-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60207652D1 (de) | Durch Säuregruppen disubstitierte Heteroaryl-Derivate und ihre Verwendung als Matrix Metalloproteinas Inhibitoren | |
| BRPI0417543A (pt) | quinolinas úteis no tratamento de doença cardiovascular | |
| NL300933I2 (nl) | Letermovir | |
| ATE269367T1 (de) | Kosmetisches mittel | |
| RU94016367A (ru) | Новые производные 2-циано-1,3-дионовые производные, способ их получения, гербицидная композиция, способ подавления роста сорняков | |
| DK1664418T3 (da) | Anvendelse af formaldehydfrie, vandige bindemidler til substrat | |
| CY1118020T1 (el) | Τροποποιημενα φθοριομενα αναλογα νουκλεοζιδιων | |
| CY1107401T1 (el) | Παραγωγα βενζοθειαζολιου πα την θεραπευτικη αντιμετωπιση της νοσου alzheimer και της νοσου parkinson | |
| TR28869A (tr) | Yeni 2-cyano-1, 3-dione türevlerine, bunlari iceren bilesimlere, hazirlama süreclerine ve herbisid olarak kullanilmalarina iliskindir. | |
| DE60108724D1 (de) | Neue pyrazin-derivate oder salze davon, pharmazeutische zusammensetzungen, die die derivate oder deren salze enthalten und intermediate zu beider herstellung | |
| DE602005025601D1 (de) | Anthranilamide, verfahren zu deren herstellung und diese enthaltende schädlingsbekämpfungsmittel | |
| BR9912494B1 (pt) | derivado de di ou trifluorometanossulfonil anilida, processo para a sua produção e herbicida contendo o referido derivado como ingrediente ativo. | |
| CY1110745T1 (el) | Παραγωγα πυρρολιδονης ως αναστολεις μαοβ | |
| EA200401114A2 (ru) | Замещённые гидроксиэтиламины | |
| CY1105362T1 (el) | Παραγωγα σουλφοναμιδιου, η παρασκευη τους και η εφαρμογη αυτων ως φαρμακα | |
| CY1111022T1 (el) | Νεοι φαρμακευτικοι συνδυασμοι για τη θεραπεια νοσων των αναπνευστικων οδων | |
| ATE144558T1 (de) | Oligonukleotiden-sequenzen zur amplifizierung von hiv-2 und siv retrovirusgenomen, ihre verwendung zur in-vitro-diagnostik von durch diese viren verursachten infektionen | |
| ATE378360T1 (de) | Polymere 3,5-dimethyl-1-adamantylammoniumsalze und deren verwendung in form von virustatika | |
| NO20070665L (no) | Derivater av 1-fenylalkankarboksylsyrer for behandlingen av neurodegenerative sykdommer | |
| ATE327980T1 (de) | 3-heterocyclyl-substituierte benzoesäurederivate | |
| DE50204181D1 (de) | Phthalsäurediamide, ein verfahren zu ihrer herstellung und ihre verwendung als schädlingsbekämpfungsmittel | |
| DE602004003737D1 (de) | Verfahren zur Herstellung von disubstituierten 9-Alkylidenfluorenen und deren Derivaten. | |
| ATE427351T1 (de) | Primaten t-lymphotrophische viren | |
| EA200600428A1 (ru) | Иммуностимулирующее и интерфероногенное средство | |
| NO20016344D0 (no) | Nye polypeptider og deres DNA |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |