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ATE377583T1 - METHOD FOR ISOLATION, PURIFICATION AND FORMULATION OF A STABLE COMMERCIAL LUTE PASTE MADE OF OLEORESIN - Google Patents

METHOD FOR ISOLATION, PURIFICATION AND FORMULATION OF A STABLE COMMERCIAL LUTE PASTE MADE OF OLEORESIN

Info

Publication number
ATE377583T1
ATE377583T1 AT05726218T AT05726218T ATE377583T1 AT E377583 T1 ATE377583 T1 AT E377583T1 AT 05726218 T AT05726218 T AT 05726218T AT 05726218 T AT05726218 T AT 05726218T AT E377583 T1 ATE377583 T1 AT E377583T1
Authority
AT
Austria
Prior art keywords
oleoresin
lutein
filtration
alcohol
lute
Prior art date
Application number
AT05726218T
Other languages
German (de)
Inventor
Sunil Bhaskaran
Vishwaraman Mohan
Original Assignee
Indus Biotech Pvt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indus Biotech Pvt Ltd filed Critical Indus Biotech Pvt Ltd
Application granted granted Critical
Publication of ATE377583T1 publication Critical patent/ATE377583T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/40—Colouring or decolouring of foods
    • A23L5/42—Addition of dyes or pigments, e.g. in combination with optical brighteners
    • A23L5/43—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives
    • A23L5/44—Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives using carotenoids or xanthophylls
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B61/00—Dyes of natural origin prepared from natural sources, e.g. vegetable sources

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

The present invention relates to a process for obtaining stabilized Lutein with about 95% yield from oleoresin at ambient temperature, said process comprising steps of dissolving cleaned oleoresin in alcohol to obtain dissolved Xanthophylls esters as clear solution on filtration, cleaning dissolved oleoresin comprising xanthophylls esters in ion-exchange resin, hydrolyzing the clear solution with base in presence of phase-transfer catalyst in alcohol medium, quenching the hydrolyzed solution in water maintaining acidic pH to obtain undissolved solids on filtration, dissolving the solids in ester to obtain ester layer on filtration, drying ester layer to obtain semi-solid residue, triturating the semi-solid residue in alcohol whereby obtaining lutein crystals of about 65% assay and an alcoholic fraction, distilling the alcoholic fraction to obtain non water-soluble fractions, and mixing the Lutein crystals with non water-soluble fractions to obtain a stable Lutein paste.
AT05726218T 2004-01-16 2005-01-17 METHOD FOR ISOLATION, PURIFICATION AND FORMULATION OF A STABLE COMMERCIAL LUTE PASTE MADE OF OLEORESIN ATE377583T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53704204P 2004-01-16 2004-01-16

Publications (1)

Publication Number Publication Date
ATE377583T1 true ATE377583T1 (en) 2007-11-15

Family

ID=34794440

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05726218T ATE377583T1 (en) 2004-01-16 2005-01-17 METHOD FOR ISOLATION, PURIFICATION AND FORMULATION OF A STABLE COMMERCIAL LUTE PASTE MADE OF OLEORESIN

Country Status (14)

Country Link
US (1) US7179930B2 (en)
EP (1) EP1704134B1 (en)
JP (1) JP4001615B2 (en)
KR (1) KR100782434B1 (en)
CN (1) CN100381414C (en)
AT (1) ATE377583T1 (en)
AU (1) AU2005205250B2 (en)
CA (1) CA2544902C (en)
DE (1) DE602005003201T2 (en)
DK (1) DK1704134T3 (en)
ES (1) ES2294694T3 (en)
PT (1) PT1704134E (en)
RU (1) RU2321582C2 (en)
WO (1) WO2005068409A1 (en)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7829126B2 (en) * 2005-10-26 2010-11-09 Abbott Laboratories Infant formulas containing docosahexaenoic acid and lutein
US20070166354A1 (en) 2005-10-26 2007-07-19 Bridget Barrett-Reis Method of reducing the risk of retinopathy of prematurity in preterm infants
AT503329A1 (en) * 2006-03-02 2007-09-15 Omnica Gmbh PROCESS FOR PREPARING A COMPOSITION CONTAINING AT LEAST ONE XANTOPHYLL
ES2318992B1 (en) * 2006-09-18 2009-12-28 Carotenoid Technologies, S.A. PROCEDURE FOR THE PREPARATION OF ESSENTIALLY PURE LUTEINE FROM MARIGOLD EXTRACTS.
CN101838229B (en) * 2009-03-19 2014-05-14 华北制药集团新药研究开发有限责任公司 Method for separating and purifying all-trans xanthophyl powder
US8716533B2 (en) 2009-05-29 2014-05-06 Kalamazoo Holdings, Inc. Methods of saponifying xanthophyll esters and isolating xanthophylls
US8247615B2 (en) 2010-05-14 2012-08-21 Kalamazoo Holdings, Inc. Process of converting esterified xanthophylls from Capsicum to non-esterified xanthophylls in high yields and purities
WO2011145112A1 (en) 2010-05-17 2011-11-24 Dynadis Biotehc (India) Private Limited Process for isolation and purification of carotenoids
EP2593516A4 (en) * 2010-07-13 2014-03-05 Rfi Llc ENHANCED NATURAL COLORS
US9458476B2 (en) 2011-04-18 2016-10-04 R.J. Reynolds Tobacco Company Method for producing glycerin from tobacco
MX353630B (en) * 2011-08-26 2018-01-22 Ptt Global Chemical Public Co Ltd Method of extracting lutein/xanthophylls from natural materials and highly purified lutein/xanthophylls obtained from the method thereof.
CN102887848A (en) * 2012-10-30 2013-01-23 长沙芬康生物科技有限公司 Method for preparing lutein crystals from marigold ointment by catalytic saponification
RU2649618C2 (en) 2012-12-19 2018-04-04 Новас Интернэшнл Инк. Xanthophyll compositions and methods for use thereof
US9289011B2 (en) * 2013-03-07 2016-03-22 R.J. Reynolds Tobacco Company Method for producing lutein from tobacco
FR3003872B1 (en) * 2013-03-29 2017-02-10 Roquette Freres PROCESS FOR STABILIZING OXIDATION-SENSITIVE METABOLITES PRODUCED BY MICROALGUES OF THE GENUS CHLORELLA
CN103262931B (en) * 2013-05-23 2015-09-30 云南瑞宝生物科技有限公司 The hard candy of water-soluble lutein ester, its preparation method and containing water-soluble lutein ester
US9265284B2 (en) 2014-01-17 2016-02-23 R.J. Reynolds Tobacco Company Process for producing flavorants and related materials
US10881133B2 (en) 2015-04-16 2021-01-05 R.J. Reynolds Tobacco Company Tobacco-derived cellulosic sugar
US10499684B2 (en) 2016-01-28 2019-12-10 R.J. Reynolds Tobacco Company Tobacco-derived flavorants
US11154087B2 (en) 2016-02-02 2021-10-26 R.J. Reynolds Tobacco Company Method for preparing flavorful compounds isolated from black liquor and products incorporating the flavorful compounds
US11091446B2 (en) 2017-03-24 2021-08-17 R.J. Reynolds Tobacco Company Methods of selectively forming substituted pyrazines
RU2750150C1 (en) * 2020-07-17 2021-06-22 Федеральное государственное автономное образовательное учреждение высшего образования "Северо-Восточный федеральный университет имени М.К.Аммосова" Method for producing stable lutein paste based on vegetable cryo raw materials with increased carotenoid content
CN114957071A (en) * 2021-02-25 2022-08-30 内蒙古昶辉生物科技股份有限公司 Method for preparing lutein by marigold ointment
CN114957072A (en) * 2021-02-25 2022-08-30 内蒙古昶辉生物科技股份有限公司 Method for preparing zeaxanthin and zeaxanthin pellet from marigold ointment

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB555636A (en) 1941-11-25 1943-09-01 Richard Lant Improvements in and relating to the treatment of vegetable seeds and particularly to the treatment of soya beans
US5382714A (en) 1994-03-17 1995-01-17 The Catholic University Of America Process for isolation, purification, and recrystallization of lutein from saponified marigold oleoresin and uses thereof
US5648564A (en) 1995-12-21 1997-07-15 Kemin Industries, Inc. Process for the formation, isolation and purification of comestible xanthophyll crystals from plants
US5876782A (en) 1997-05-14 1999-03-02 Kemin Industries, Inc. Method for the conversion of xanthophylls in plant material
US6262284B1 (en) * 1998-10-21 2001-07-17 University Of Maryland Process for extraction and purification of lutein, zeaxanthin and rare carotenoids from marigold flowers and plants
US6504067B1 (en) 1999-11-24 2003-01-07 Industrial Organica S.A. De C.V. Process to obtain xanthophyll concentrates of high purity
WO2002060864A1 (en) * 2001-01-30 2002-08-08 Sabinsa Corporation Process of obtaining compositions of stable lutein and lutein derivatives
US6380442B1 (en) 2001-10-10 2002-04-30 Bioactives, Llc Process for the isolation of mixed carotenoids from plants

Also Published As

Publication number Publication date
JP2007517863A (en) 2007-07-05
EP1704134A1 (en) 2006-09-27
ES2294694T3 (en) 2008-04-01
US7179930B2 (en) 2007-02-20
CN100381414C (en) 2008-04-16
DE602005003201T2 (en) 2008-11-06
WO2005068409A1 (en) 2005-07-28
CN1860091A (en) 2006-11-08
KR100782434B1 (en) 2007-12-05
RU2321582C2 (en) 2008-04-10
DE602005003201D1 (en) 2007-12-20
AU2005205250A1 (en) 2005-07-28
DK1704134T3 (en) 2008-01-28
JP4001615B2 (en) 2007-10-31
CA2544902C (en) 2008-02-05
PT1704134E (en) 2007-12-28
US20050182280A1 (en) 2005-08-18
EP1704134B1 (en) 2007-11-07
RU2006116475A (en) 2007-11-20
AU2005205250B2 (en) 2008-11-13
KR20060090272A (en) 2006-08-10
CA2544902A1 (en) 2005-07-28

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