ATE376426T1 - Isolierung des hepatoprotektiven wirkstoffes acteosid aus colerbrookea oppositifolia - Google Patents
Isolierung des hepatoprotektiven wirkstoffes acteosid aus colerbrookea oppositifoliaInfo
- Publication number
- ATE376426T1 ATE376426T1 AT03816508T AT03816508T ATE376426T1 AT E376426 T1 ATE376426 T1 AT E376426T1 AT 03816508 T AT03816508 T AT 03816508T AT 03816508 T AT03816508 T AT 03816508T AT E376426 T1 ATE376426 T1 AT E376426T1
- Authority
- AT
- Austria
- Prior art keywords
- acteoside
- fractions
- colerbrookea
- oppositifolia
- residue
- Prior art date
Links
- 229930185474 acteoside Natural products 0.000 title abstract 5
- FBSKJMQYURKNSU-ZLSOWSIRSA-N acteoside Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1O[C@H]1[C@H](OC(=O)\C=C\C=2C=C(O)C(O)=CC=2)[C@@H](CO)O[C@@H](OCCC=2C=C(O)C(O)=CC=2)[C@@H]1O FBSKJMQYURKNSU-ZLSOWSIRSA-N 0.000 title abstract 5
- FBSKJMQYURKNSU-UKQWSTALSA-N acteoside I Natural products C[C@@H]1O[C@H](O[C@@H]2[C@@H](O)[C@H](OCCc3ccc(O)c(O)c3)O[C@H](CO)[C@H]2OC(=O)C=Cc4ccc(O)c(O)c4)[C@H](O)[C@H](O)[C@H]1O FBSKJMQYURKNSU-UKQWSTALSA-N 0.000 title abstract 5
- QFRYQWYZSQDFOS-UHFFFAOYSA-N verbascoside Natural products CC1OC(COC2C(O)C(COC3OC(C(O)C(O)C3O)C(=O)O)OC(Oc4cc(O)cc5OC(=CC(=O)c45)c6ccc(O)c(O)c6)C2O)C(O)C(O)C1O QFRYQWYZSQDFOS-UHFFFAOYSA-N 0.000 title abstract 5
- 238000002955 isolation Methods 0.000 title abstract 2
- 230000002443 hepatoprotective effect Effects 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 6
- 238000000034 method Methods 0.000 abstract 5
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 4
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 abstract 2
- 238000001035 drying Methods 0.000 abstract 2
- 239000000843 powder Substances 0.000 abstract 2
- 239000006228 supernatant Substances 0.000 abstract 2
- 238000005377 adsorption chromatography Methods 0.000 abstract 1
- 239000002034 butanolic fraction Substances 0.000 abstract 1
- 238000004440 column chromatography Methods 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000011521 glass Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2003/001180 WO2004087184A1 (en) | 2003-03-31 | 2003-03-31 | Isolation of the hepatoprotective agent acteoside from colerbrokea oppositifolia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE376426T1 true ATE376426T1 (de) | 2007-11-15 |
Family
ID=33104924
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03816508T ATE376426T1 (de) | 2003-03-31 | 2003-03-31 | Isolierung des hepatoprotektiven wirkstoffes acteosid aus colerbrookea oppositifolia |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1617853B1 (de) |
| JP (1) | JP4486508B2 (de) |
| CN (1) | CN100467033C (de) |
| AT (1) | ATE376426T1 (de) |
| AU (1) | AU2003215819A1 (de) |
| DE (1) | DE60317111T2 (de) |
| WO (1) | WO2004087184A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109776631A (zh) * | 2019-01-30 | 2019-05-21 | 中国人民解放军联勤保障部队第九二八医院 | 一种毛蕊花糖苷的制备方法 |
| CN117205131B (zh) * | 2023-11-09 | 2024-01-26 | 云南雅赫生物科技有限公司 | 具有美白和抗氧化作用的羽萼叶碱性水提物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03271227A (ja) * | 1990-03-20 | 1991-12-03 | Tsumura & Co | 糖尿病治療剤 |
| AU670742B2 (en) * | 1991-03-21 | 1996-08-01 | Parfums Christian Dior | Novel derivative of caffeic acid, oraposide, cosmetic or pharmaceutical, particularly dermatological, composition containing it |
-
2003
- 2003-03-31 WO PCT/IB2003/001180 patent/WO2004087184A1/en not_active Ceased
- 2003-03-31 CN CNB038265435A patent/CN100467033C/zh not_active Expired - Fee Related
- 2003-03-31 AU AU2003215819A patent/AU2003215819A1/en not_active Abandoned
- 2003-03-31 DE DE60317111T patent/DE60317111T2/de not_active Expired - Lifetime
- 2003-03-31 AT AT03816508T patent/ATE376426T1/de not_active IP Right Cessation
- 2003-03-31 EP EP03816508A patent/EP1617853B1/de not_active Expired - Lifetime
- 2003-03-31 JP JP2004570051A patent/JP4486508B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP4486508B2 (ja) | 2010-06-23 |
| CN1771048A (zh) | 2006-05-10 |
| CN100467033C (zh) | 2009-03-11 |
| WO2004087184A1 (en) | 2004-10-14 |
| DE60317111T2 (de) | 2008-07-31 |
| JP2006514675A (ja) | 2006-05-11 |
| AU2003215819A1 (en) | 2004-10-25 |
| EP1617853A1 (de) | 2006-01-25 |
| DE60317111D1 (de) | 2007-12-06 |
| EP1617853B1 (de) | 2007-10-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101684430B (zh) | 一种当归烟用香料及其制备方法 | |
| CN102846784B (zh) | 鸡矢藤水提取物、其制备方法和用途 | |
| CN113181254B (zh) | 一种杏花蜂花粉在提取酚胺化合物中的应用、从杏花蜂花粉中提取酚胺化合物的方法 | |
| KR101251589B1 (ko) | 도라지 또는 도라지 추출물로부터의 순도 및 유효 사포닌 함량이 증가된 조사포닌 조성물의 제조방법 | |
| CN101337876B (zh) | 一种从啤酒花中提取黄腐酚的方法 | |
| CN108653368A (zh) | 一种珊瑚树萜类成分的制备方法 | |
| CN101747195B (zh) | 菊芋中二咖啡酰奎尼酸组分的分离提纯方法 | |
| Cardellina | Step gradient elution in gel permeation chromatography. A new approach to natural products separations | |
| DE60317111D1 (de) | Isolierung des hepatoprotektiven wirkstoffes acteosid aus colerbrookea oppositifolia | |
| CN103304611B (zh) | 一种从瓜蒌皮中分离纯化3种黄酮苷的方法 | |
| KR20120024236A (ko) | 초고압 재결정화 방법을 이용하여 녹차로부터 ｅｇｃｇ를 분리, 정제하는 방법 | |
| CN103342689B (zh) | 从瓜蒌皮中分离纯化木犀草素、芹菜素和香叶木素的方法 | |
| CN105434539A (zh) | 一种荷叶黄酮的组合物 | |
| CN104031107A (zh) | 一种从灵芝中提取灵芝酸a的方法 | |
| CN104876900A (zh) | 一种从木香中提取、分离纯化木香烃内酯和去氢木香内酯的方法 | |
| CN102250183B (zh) | 一种以人参花蕾为原材料制备高纯度人参皂苷Re的方法 | |
| CN101618052A (zh) | 从沙棘叶中提取总黄酮的工艺方法 | |
| CN116162013A (zh) | 一种从美汉草中提取分离β-石竹烯的方法 | |
| CN106986881A (zh) | 一种异苯并呋喃类化合物的制备方法和应用 | |
| CN104147183B (zh) | 一种从栀子豉汤中分离纯化总环烯醚萜苷和总大豆异黄酮的方法 | |
| CN112321664A (zh) | 提取分离纯化桦褐孔菌醇的方法 | |
| CN114634537A (zh) | 金叶子二萜的制备方法及其应用 | |
| Wang et al. | Investigation on ultrasound-assisted extraction of three dibenzylbutyrolactone lignans from Hemistepta lyrata | |
| CN102942456B (zh) | 从桑枝中提取氧化芪三酚的方法 | |
| CN114014855B (zh) | 沙棘果渣中分离纯化生物碱类化合物的方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |