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ATE374018T1 - Prozess zur herstellung von nano- und mikrokapseln aus spinnenseidenprotein - Google Patents

Prozess zur herstellung von nano- und mikrokapseln aus spinnenseidenprotein

Info

Publication number
ATE374018T1
ATE374018T1 AT05016712T AT05016712T ATE374018T1 AT E374018 T1 ATE374018 T1 AT E374018T1 AT 05016712 T AT05016712 T AT 05016712T AT 05016712 T AT05016712 T AT 05016712T AT E374018 T1 ATE374018 T1 AT E374018T1
Authority
AT
Austria
Prior art keywords
spider silk
silk protein
producing nano
micro capsules
nano
Prior art date
Application number
AT05016712T
Other languages
English (en)
Inventor
Thomas Scheibel
Andreas Bausch
Daniel Huemmerich
Kevin Hermanson
Original Assignee
Univ Muenchen Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Muenchen Tech filed Critical Univ Muenchen Tech
Application granted granted Critical
Publication of ATE374018T1 publication Critical patent/ATE374018T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/413—Nanosized, i.e. having sizes below 100 nm

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Birds (AREA)
  • Nanotechnology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Insects & Arthropods (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
AT05016712T 2005-08-01 2005-08-01 Prozess zur herstellung von nano- und mikrokapseln aus spinnenseidenprotein ATE374018T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05016712A EP1757276B1 (de) 2005-08-01 2005-08-01 Prozess zur Herstellung von Nano- und Mikrokapseln aus Spinnenseidenprotein

Publications (1)

Publication Number Publication Date
ATE374018T1 true ATE374018T1 (de) 2007-10-15

Family

ID=35197006

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05016712T ATE374018T1 (de) 2005-08-01 2005-08-01 Prozess zur herstellung von nano- und mikrokapseln aus spinnenseidenprotein

Country Status (12)

Country Link
US (2) US8372436B2 (de)
EP (1) EP1757276B1 (de)
JP (1) JP5129746B2 (de)
CN (1) CN101309676B (de)
AT (1) ATE374018T1 (de)
CA (1) CA2617530C (de)
DE (1) DE602005002654T2 (de)
DK (1) DK1757276T3 (de)
ES (1) ES2294606T3 (de)
PL (1) PL1757276T3 (de)
PT (1) PT1757276E (de)
WO (1) WO2007014755A1 (de)

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JPS6092337A (ja) * 1983-10-26 1985-05-23 Sekisui Plastics Co Ltd 発泡フエノ−ル樹脂成形物の製造方法
EP1979055A2 (de) * 2006-01-20 2008-10-15 Basf Se Verwendung von protein-microbeads in der kosmetik
EP2097117B1 (de) * 2006-12-11 2013-05-22 Medizinische Hochschule Hannover Implantat aus vernetzten spinnen-seidenfäden
JP2008201767A (ja) * 2007-01-24 2008-09-04 Fujifilm Corp 頭髪用組成物
US20080175807A1 (en) 2007-01-24 2008-07-24 Fujifilm Corporation Composition for hair
JP2008255020A (ja) * 2007-04-02 2008-10-23 Fujifilm Corp 抗老化皮膚外用剤
CA2683974A1 (en) * 2007-04-18 2008-10-30 The Regents Of The University Of California Protein-modified nano-droplets, compositions and methods of production
CN101855239B (zh) * 2007-06-20 2013-11-06 巴斯夫欧洲公司 合成的重复蛋白及其生产和用途
EP2506837B1 (de) 2009-11-30 2020-07-01 Amsilk GmbH Spinnenseidenpartikel zur kontrollierten und verzögerten freisetzung von substanzen
EP2549986B1 (de) * 2010-03-24 2019-10-30 Northeastern University Makrophagenabgabe an mehrere ziele
KR101494711B1 (ko) 2011-11-04 2015-02-26 동아대학교 산학협력단 산왕거미 유래 메이저 엠풀레이트 스피드로인 단백질의 반복적인 ｃ-말단 영역의 폴리펩티드 서열 및 이를 코딩하는 염기서열
WO2014012099A1 (en) * 2012-07-13 2014-01-16 Tufts University Encapsulation of fragrance and/or flavors in silk fibroin biomaterials
MX2015000554A (es) * 2012-07-13 2015-09-28 Univ Tufts Encapsulación de fases inmisibles en biomateriales de fibroína de seda.
JP6450680B2 (ja) * 2012-09-06 2019-01-09 アーエムシルク ゲーエムベーハー 高靱性シルク繊維を作製する方法
MX367597B (es) * 2013-03-15 2019-08-28 Patheon Softgels Inc Cápsulas a base de seda.
GB201415681D0 (en) * 2014-09-04 2014-10-22 Cambridge Entpr Ltd And President And Fellows Of Harvard College Protien Capsules
DE102014218502A1 (de) 2014-09-16 2016-03-17 Henkel Ag & Co. Kgaa Proteinhaltiges Reinigungsmittel
DE102014218503A1 (de) 2014-09-16 2016-03-17 Henkel Ag & Co. Kgaa Proteinhaltiges Waschmittel
DE102014218507A1 (de) 2014-09-16 2016-03-17 Henkel Ag & Co. Kgaa Spinnenseidenproteine als Enzymstabilisatoren
EA035551B1 (ru) 2014-12-02 2020-07-06 Силк Терапьютикс, Инк. Изделие
CN104927777B (zh) * 2015-06-02 2018-04-24 清华大学深圳研究生院 相变储能微胶囊制备方法及应用
WO2017011679A1 (en) 2015-07-14 2017-01-19 Silk Therapeutics, Inc. Silk performance apparel and products and methods of preparing the same
ES3024660T3 (en) 2016-06-22 2025-06-05 Amsilk Gmbh Articles comprising a silk polypeptide for antigen delivery
DE102016222480B4 (de) 2016-11-16 2020-02-13 Adidas Ag Bekleidungsstück, das Spinnenseide aufweist oder Schuh, der Spinnenseide aufweist, und ein entsprechendes Herstellungsverfahren
WO2019067745A1 (en) 2017-09-27 2019-04-04 Silk, Inc. SILK-COATED FABRICS, PRODUCTS AND PREPARATION METHODS THEREFOR
EP3836786A1 (de) 2018-08-17 2021-06-23 AMSilk GmbH Verwendung eines strukturpolypeptids zur pflanzenbeschichtung
CN109329910A (zh) * 2018-09-28 2019-02-15 青岛大学 一种蜘蛛丝组合物口服液的制备方法
US20220273526A1 (en) * 2019-07-12 2022-09-01 Bolt Threads, Inc. Recombinant spider silk extrudate formulations
US12403216B2 (en) * 2019-10-18 2025-09-02 Trustees Of Tufts College Chemical modification of silk fibroin for fabrication of enzymatically crosslinked hydrogels with tunable gelation kinetics and bioactivity
CN111214385B (zh) * 2020-03-13 2022-05-17 珀莱雅化妆品股份有限公司 一种负载皮肤营养剂的纳米粒乳液及其制备方法
WO2022138640A1 (ja) * 2020-12-24 2022-06-30 国立大学法人筑波大学 フィブロインマイクロ球体及びその製造方法
US12391912B2 (en) 2021-10-26 2025-08-19 Rensselaer Polytechnic Institute Systems and methods for increased production of recombinant biopolymers via genome engineering and downregulation of basal expression
EP4476048A1 (de) 2022-02-10 2024-12-18 AMSilk GmbH Gradientendruckbehälter und druckverfahren

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FR2683159B1 (fr) * 1991-10-31 1994-02-25 Coletica Procede de fabrication de nanocapsules a paroi a base de proteines reticulees; nanocapsules ainsi obtenues et compositions cosmetiques, pharmaceutiques et alimentaires en comportant application.
JP3094181B2 (ja) * 1992-04-09 2000-10-03 清 山内 再生天然ケラチンを壁材とするマイクロカプセル及びその製造方法
JPH08511426A (ja) 1993-06-15 1996-12-03 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 新規の組換え産生性クモシルクアナログ
JPH08268905A (ja) 1995-03-31 1996-10-15 Takayuki Nagashima コロイド状絹フィブロイン及びそれを含有する組成物
JPH08295697A (ja) 1995-04-26 1996-11-12 Kanebo Ltd 高濃度絹フィブロイン水溶液の製造方法
JP2997758B2 (ja) 1996-01-23 2000-01-11 農林水産省蚕糸・昆虫農業技術研究所長 創傷被覆材
JP3537297B2 (ja) 1996-08-15 2004-06-14 聖治 寺内 フィブロイン流動体及びその製造方法
FR2774588B1 (fr) 1998-02-11 2000-05-05 Oreal Composition cosmetique ou dermatologique contenant au moins une proteine de soie d'arachnides naturelle, recombinante ou un analogue
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CN1288193C (zh) * 2004-03-10 2006-12-06 复旦大学 蚕丝蛋白纳米微球及其制备方法
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Also Published As

Publication number Publication date
ES2294606T3 (es) 2008-04-01
CN101309676B (zh) 2012-02-29
JP2009502492A (ja) 2009-01-29
EP1757276B1 (de) 2007-09-26
JP5129746B2 (ja) 2013-01-30
US20130136779A1 (en) 2013-05-30
US8372436B2 (en) 2013-02-12
CA2617530C (en) 2013-10-01
PT1757276E (pt) 2008-01-02
PL1757276T3 (pl) 2008-02-29
DE602005002654D1 (de) 2007-11-08
CN101309676A (zh) 2008-11-19
US8729238B2 (en) 2014-05-20
DE602005002654T2 (de) 2008-06-19
EP1757276A1 (de) 2007-02-28
US20100056438A1 (en) 2010-03-04
WO2007014755A1 (en) 2007-02-08
DK1757276T3 (da) 2008-02-04
CA2617530A1 (en) 2007-02-08

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