ATE365546T1 - Verfahren zur herstellung von komprimierten festen dosierungsformen, das gut zur verwendung mit schlecht wasserlöslichen arzneistoffen geeignet ist, und danach hergestellte komprimierte feste dosierungsformen - Google Patents
Verfahren zur herstellung von komprimierten festen dosierungsformen, das gut zur verwendung mit schlecht wasserlöslichen arzneistoffen geeignet ist, und danach hergestellte komprimierte feste dosierungsformenInfo
- Publication number
- ATE365546T1 ATE365546T1 AT04810659T AT04810659T ATE365546T1 AT E365546 T1 ATE365546 T1 AT E365546T1 AT 04810659 T AT04810659 T AT 04810659T AT 04810659 T AT04810659 T AT 04810659T AT E365546 T1 ATE365546 T1 AT E365546T1
- Authority
- AT
- Austria
- Prior art keywords
- dosage forms
- solid dosage
- compressed solid
- water soluble
- poorly water
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 239000007909 solid dosage form Substances 0.000 title 2
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title 1
- 229910001868 water Inorganic materials 0.000 title 1
- 239000008187 granular material Substances 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000007787 solid Substances 0.000 abstract 3
- 229920002472 Starch Polymers 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 235000019698 starch Nutrition 0.000 abstract 2
- 239000008107 starch Substances 0.000 abstract 2
- 238000001035 drying Methods 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002156 mixing Methods 0.000 abstract 1
- 238000009736 wetting Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2004/037462 WO2006052254A2 (en) | 2004-11-10 | 2004-11-10 | Compressed solid dosage form manufacturing process well-suited for use with drugs of low aqueous solubility and compressed solid dosage forms made thereby |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE365546T1 true ATE365546T1 (de) | 2007-07-15 |
Family
ID=36218312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04810659T ATE365546T1 (de) | 2004-11-10 | 2004-11-10 | Verfahren zur herstellung von komprimierten festen dosierungsformen, das gut zur verwendung mit schlecht wasserlöslichen arzneistoffen geeignet ist, und danach hergestellte komprimierte feste dosierungsformen |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1729735B1 (de) |
| JP (1) | JP4842960B2 (de) |
| AT (1) | ATE365546T1 (de) |
| AU (1) | AU2004324858B2 (de) |
| CA (1) | CA2587295A1 (de) |
| DE (1) | DE602004007302T2 (de) |
| DK (1) | DK1729735T3 (de) |
| IL (2) | IL182549A (de) |
| PT (1) | PT1729735E (de) |
| WO (1) | WO2006052254A2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2242483B1 (de) * | 2007-12-21 | 2013-02-20 | Synthon B.V. | Raloxifen-zusammensetzung |
| EP2271320A4 (de) * | 2008-04-02 | 2011-05-18 | Reddys Lab Ltd Dr | Pharmazeutische raloxifenformulierungen |
| WO2011000581A2 (en) | 2009-07-02 | 2011-01-06 | Synthon B.V. | Raloxifene composition |
| EP3650010B1 (de) * | 2018-11-09 | 2021-01-06 | Siegfried AG | Verbesserter tablettierungsprozess |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW366342B (en) * | 1992-07-28 | 1999-08-11 | Lilly Co Eli | The use of 2-phenyl-3-aroylbenzothiophenes in inhibiting bone loss |
| US5478847A (en) * | 1994-03-02 | 1995-12-26 | Eli Lilly And Company | Methods of use for inhibiting bone loss and lowering serum cholesterol |
| CA2213700C (en) * | 1995-02-28 | 2002-04-02 | Hoechst Marion Roussel, Inc. | Pharmaceutical composition for piperidinoalkanol compounds |
| IL115357A (en) * | 1995-09-20 | 2000-01-31 | Teva Pharma | Stable compositions containing N-propargyl-1-aminoindan and polyhydric alcohols |
| WO2001097782A1 (en) * | 2000-06-16 | 2001-12-27 | Teva Pharmaceutical Industries, Ltd. | Stable gabapentin having ph within a controlled range |
| AR029538A1 (es) * | 2000-07-06 | 2003-07-02 | Wyeth Corp | Composiciones farmaceuticas de agentes estrogenicos |
| US20040185097A1 (en) * | 2003-01-31 | 2004-09-23 | Glenmark Pharmaceuticals Ltd. | Controlled release modifying complex and pharmaceutical compositions thereof |
-
2004
- 2004-11-10 CA CA002587295A patent/CA2587295A1/en not_active Abandoned
- 2004-11-10 EP EP04810659A patent/EP1729735B1/de not_active Expired - Lifetime
- 2004-11-10 DK DK04810659T patent/DK1729735T3/da active
- 2004-11-10 AT AT04810659T patent/ATE365546T1/de not_active IP Right Cessation
- 2004-11-10 DE DE602004007302T patent/DE602004007302T2/de not_active Expired - Lifetime
- 2004-11-10 AU AU2004324858A patent/AU2004324858B2/en not_active Expired - Fee Related
- 2004-11-10 JP JP2007541148A patent/JP4842960B2/ja not_active Expired - Lifetime
- 2004-11-10 PT PT04810659T patent/PT1729735E/pt unknown
- 2004-11-10 WO PCT/US2004/037462 patent/WO2006052254A2/en not_active Ceased
-
2007
- 2007-04-15 IL IL182549A patent/IL182549A/en active IP Right Grant
-
2009
- 2009-08-18 IL IL200447A patent/IL200447A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT1729735E (pt) | 2007-08-06 |
| DE602004007302D1 (de) | 2007-08-09 |
| JP2008519834A (ja) | 2008-06-12 |
| AU2004324858A1 (en) | 2006-05-18 |
| HK1096875A1 (en) | 2007-06-15 |
| IL182549A (en) | 2010-11-30 |
| EP1729735B1 (de) | 2007-06-27 |
| CA2587295A1 (en) | 2006-05-18 |
| WO2006052254A2 (en) | 2006-05-18 |
| AU2004324858B2 (en) | 2009-12-10 |
| JP4842960B2 (ja) | 2011-12-21 |
| WO2006052254A3 (en) | 2006-08-17 |
| IL200447A0 (en) | 2011-07-31 |
| IL182549A0 (en) | 2007-09-20 |
| DK1729735T3 (da) | 2007-10-08 |
| EP1729735A2 (de) | 2006-12-13 |
| DE602004007302T2 (de) | 2008-03-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |