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ATE360413T1 - Zusammensetzungen mit verzögerter freigabe, verfahren zu deren herstellung und verwendung - Google Patents

Zusammensetzungen mit verzögerter freigabe, verfahren zu deren herstellung und verwendung

Info

Publication number
ATE360413T1
ATE360413T1 AT00944418T AT00944418T ATE360413T1 AT E360413 T1 ATE360413 T1 AT E360413T1 AT 00944418 T AT00944418 T AT 00944418T AT 00944418 T AT00944418 T AT 00944418T AT E360413 T1 ATE360413 T1 AT E360413T1
Authority
AT
Austria
Prior art keywords
release compositions
salt
lactic acid
polymer
acid
Prior art date
Application number
AT00944418T
Other languages
English (en)
Inventor
Yasutaka Igari
Yoshio Hata
Kazumichi Yamamoto
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Application granted granted Critical
Publication of ATE360413T1 publication Critical patent/ATE360413T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT00944418T 1999-07-15 2000-07-13 Zusammensetzungen mit verzögerter freigabe, verfahren zu deren herstellung und verwendung ATE360413T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP20188799 1999-07-15

Publications (1)

Publication Number Publication Date
ATE360413T1 true ATE360413T1 (de) 2007-05-15

Family

ID=16448493

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00944418T ATE360413T1 (de) 1999-07-15 2000-07-13 Zusammensetzungen mit verzögerter freigabe, verfahren zu deren herstellung und verwendung

Country Status (21)

Country Link
US (2) US7265157B1 (de)
EP (1) EP1197208B1 (de)
KR (1) KR20020012312A (de)
CN (1) CN1361685A (de)
AT (1) ATE360413T1 (de)
AU (1) AU5853000A (de)
BR (1) BR0012400A (de)
CA (1) CA2378714A1 (de)
CZ (1) CZ2002114A3 (de)
DE (1) DE60034568T2 (de)
HK (1) HK1042237A1 (de)
HU (1) HUP0202880A3 (de)
IL (1) IL147417A0 (de)
MX (1) MXPA02000461A (de)
NO (1) NO20020084L (de)
NZ (1) NZ516466A (de)
PL (1) PL352499A1 (de)
RU (1) RU2002103718A (de)
SK (1) SK342002A3 (de)
WO (1) WO2001005380A1 (de)
ZA (1) ZA200200347B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ505651A (en) * 1998-01-16 2003-08-29 Takeda Chemical Industries Ltd Sustained release composition comprising biologically active substance, hydroxynaphthoic acid and biodegradable polymer
CA2355186C (en) * 1998-12-15 2008-03-18 Takeda Chemical Industries, Ltd. Process for producing polymer
CN1269870C (zh) 2000-08-07 2006-08-16 和光纯药工业株式会社 乳酸聚合物及其制备方法
WO2002078669A1 (fr) * 2001-03-30 2002-10-10 Takeda Chemical Industries, Ltd. Solutions medicinales
CA2444727A1 (en) * 2001-04-25 2002-11-07 Takeda Chemical Industries, Ltd. Agents for preventing postoperative recurrence of premenopausal breast cancer
US6693134B2 (en) 2001-05-29 2004-02-17 Chemokine Therapeutics Corporation Bicyclic aromatic chemokine receptor ligands
TW200526267A (en) * 2001-06-29 2005-08-16 Takeda Chemical Industries Ltd Controlled release composition and method of producing the same
KR100994658B1 (ko) * 2001-12-26 2010-11-16 다케다 야쿠힌 고교 가부시키가이샤 신규 마이크로스피어 및 이들의 제조 방법
CA2490351C (en) 2002-06-25 2011-11-01 Takeda Pharmaceutical Company Limited Process for producing sustained-release composition
WO2005009357A2 (en) * 2003-07-23 2005-02-03 Pr Pharmaceuticals, Inc. Controlled release compositions
US20050064045A1 (en) * 2003-09-18 2005-03-24 Sheng-Ping Zhong Injectable therapeutic formulations
US7906125B2 (en) 2003-09-18 2011-03-15 Boston Scientific Scimed, Inc. Solid or semi-solid therapeutic formulations
TW200529890A (en) 2004-02-10 2005-09-16 Takeda Pharmaceutical Sustained-release preparations
EP1679065A1 (de) 2005-01-07 2006-07-12 OctoPlus Sciences B.V. Zubereitung mit kontrollierter Freisetzung von Interferon auf PEGT/PBT-Block-Copolymer-Basis
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
US8263109B2 (en) 2005-05-09 2012-09-11 Boston Scientific Scimed, Inc. Injectable bulking compositions
US20070149457A1 (en) * 2005-12-13 2007-06-28 Byron Rubin Stable solid forms of enterostatin
AU2006326502A1 (en) * 2005-12-13 2007-06-21 Harkness Pharmaceuticals, Inc. Methods of treating obesity using enterostatin
EP2051725A4 (de) * 2006-07-11 2011-06-15 Harkness Pharmaceuticals Inc Verfahren zur behandlung von fettsucht mit sättigungsfaktoren
US7858663B1 (en) * 2007-10-31 2010-12-28 Pisgah Laboratories, Inc. Physical and chemical properties of thyroid hormone organic acid addition salts
EA016176B1 (ru) 2006-12-18 2012-02-28 Такеда Фармасьютикал Компани Лимитед Композиция с замедленным высвобождением и способ её получения

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4459196A (en) 1995-01-23 1996-08-14 Takeda Chemical Industries Ltd. Sustained-release preparation and use
CA2219698C (en) 1996-10-31 2007-09-04 Takeda Chemical Industries, Ltd. Sustained-release preparation
WO1998032423A1 (en) * 1997-01-29 1998-07-30 Takeda Chemical Industries, Ltd. Sustained-release microspheres, their production and use
NZ505651A (en) 1998-01-16 2003-08-29 Takeda Chemical Industries Ltd Sustained release composition comprising biologically active substance, hydroxynaphthoic acid and biodegradable polymer
JPH11269094A (ja) * 1998-01-16 1999-10-05 Takeda Chem Ind Ltd 徐放性組成物、その製造法および用途
CA2355186C (en) * 1998-12-15 2008-03-18 Takeda Chemical Industries, Ltd. Process for producing polymer

Also Published As

Publication number Publication date
US20080014237A1 (en) 2008-01-17
PL352499A1 (en) 2003-08-25
US7265157B1 (en) 2007-09-04
NO20020084D0 (no) 2002-01-08
HUP0202880A3 (en) 2003-04-28
WO2001005380A1 (fr) 2001-01-25
DE60034568T2 (de) 2008-01-03
MXPA02000461A (es) 2002-07-30
CZ2002114A3 (cs) 2002-04-17
HUP0202880A2 (hu) 2003-01-28
RU2002103718A (ru) 2003-10-10
DE60034568D1 (de) 2007-06-06
AU5853000A (en) 2001-02-05
NZ516466A (en) 2003-02-28
BR0012400A (pt) 2002-05-21
NO20020084L (no) 2002-03-14
ZA200200347B (en) 2003-03-26
EP1197208B1 (de) 2007-04-25
CA2378714A1 (en) 2001-01-25
HK1042237A1 (en) 2002-08-09
CN1361685A (zh) 2002-07-31
KR20020012312A (ko) 2002-02-15
EP1197208A1 (de) 2002-04-17
IL147417A0 (en) 2002-08-14
EP1197208A4 (de) 2004-06-30
SK342002A3 (en) 2002-05-09

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