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ATE341626T1 - Membranproteine aus säugetierzellen; verwandte reagentien - Google Patents

Membranproteine aus säugetierzellen; verwandte reagentien

Info

Publication number
ATE341626T1
ATE341626T1 AT98937993T AT98937993T ATE341626T1 AT E341626 T1 ATE341626 T1 AT E341626T1 AT 98937993 T AT98937993 T AT 98937993T AT 98937993 T AT98937993 T AT 98937993T AT E341626 T1 ATE341626 T1 AT E341626T1
Authority
AT
Austria
Prior art keywords
membrane proteins
mammal cells
related reagents
cells
proteins
Prior art date
Application number
AT98937993T
Other languages
English (en)
Inventor
Alexander B H Bakker
Joseph H Phillips Jr
Lewis L Lanier
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of ATE341626T1 publication Critical patent/ATE341626T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT98937993T 1997-08-01 1998-07-31 Membranproteine aus säugetierzellen; verwandte reagentien ATE341626T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US90490597A 1997-08-01 1997-08-01
US6371797P 1997-10-29 1997-10-29
US99082097A 1997-12-15 1997-12-15
US6969297P 1997-12-16 1997-12-16
US8916898P 1998-06-12 1998-06-12

Publications (1)

Publication Number Publication Date
ATE341626T1 true ATE341626T1 (de) 2006-10-15

Family

ID=27535631

Family Applications (2)

Application Number Title Priority Date Filing Date
AT98937993T ATE341626T1 (de) 1997-08-01 1998-07-31 Membranproteine aus säugetierzellen; verwandte reagentien
AT06019631T ATE523593T1 (de) 1997-08-01 1998-07-31 Membranproteine aus säugetierzellen und verwandte reagentien

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT06019631T ATE523593T1 (de) 1997-08-01 1998-07-31 Membranproteine aus säugetierzellen und verwandte reagentien

Country Status (8)

Country Link
EP (3) EP1798287A3 (de)
JP (3) JP2001512017A (de)
AT (2) ATE341626T1 (de)
AU (1) AU8661498A (de)
DE (1) DE69836082T2 (de)
ES (1) ES2274574T3 (de)
PT (1) PT1003861E (de)
WO (1) WO1999006557A2 (de)

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US7196164B2 (en) 1997-07-08 2007-03-27 Human Genome Sciences, Inc. Secreted protein HHTLF25
EP1557425A3 (de) * 1997-07-08 2005-08-17 Human Genome Sciences, Inc. Humanes sekeretiertes Protein
US20040045041A1 (en) * 2000-09-20 2004-03-04 Eric Vivier Means for the identification compounds capable of inhibiting karap-transduced signals
EP1351702B1 (de) * 2000-12-08 2015-03-04 Bioprovar Corporation Trem-1-Spleissvariante zur Modifikation von Immunreaktionen
CA2433474A1 (en) * 2001-02-23 2002-09-06 Human Genome Sciences, Inc. 70 human secreted proteins
EP1817590A2 (de) * 2004-11-08 2007-08-15 Schering Corporation Tumorassoziation von mdl-1 und entsprechende verfahren
TW200738752A (en) * 2006-01-31 2007-10-16 Bayer Schering Pharma Ag Modulation of MDL-1 activity for treatment of inflammatory disease
CA2685015A1 (en) 2007-04-23 2008-11-06 Schering Corporation Anti-mdl-1 antibodies
US20130323246A1 (en) * 2011-02-18 2013-12-05 Merck Sharp & Dohme Corp. Use of mdl-1 antagonists to treat spondylarthropathy
US20140227719A1 (en) 2011-09-23 2014-08-14 Merck Sharp & Dohme Corp Mdl-1 ligand
KR102038310B1 (ko) 2011-11-16 2019-11-01 베링거 인겔하임 인터내셔날 게엠베하 항 il-36r 항체
AR090915A1 (es) 2012-05-04 2014-12-17 Intervet Int Bv Proteina de fusion de proteina linfopoyetina estromal timica canina con la region fc de igg
US9511092B2 (en) 2013-01-28 2016-12-06 St. Jude Children's Research Hospital, Inc. Chimeric receptor with NKG2D specificity for use in cell therapy against cancer and infectious disease
WO2014126902A1 (en) * 2013-02-15 2014-08-21 Thomas Jefferson University Kit for tumor imaging
AU2015259877B2 (en) 2014-05-15 2021-02-25 National University Of Singapore Modified natural killer cells and uses thereof
KR20250067191A (ko) 2014-09-17 2025-05-14 노파르티스 아게 입양 면역요법을 위한 키메라 수용체에 의한 세포독성 세포의 표적화
BR112019019917A2 (pt) 2017-03-27 2020-04-22 Nat Univ Singapore receptores quiméricos nkg2d truncados e seus usos em imunoterapia de células exterminadoras naturais
AU2019219454A1 (en) 2018-02-09 2020-08-27 National University Of Singapore Activating chimeric receptors and uses thereof in natural killer cell immunotherapy
SG11202008976YA (en) 2018-04-02 2020-10-29 Nat Univ Singapore Neutralization of human cytokines with membrane-bound anti-cytokine non-signaling binders expressed in immune cells
CN108728527B (zh) * 2018-06-06 2020-06-09 青岛泱深生物医药有限公司 Hcst基因作为诊治子痫前期的靶标
JP7560882B2 (ja) 2018-08-29 2024-10-03 ナショナル ユニヴァーシティー オブ シンガポール 遺伝子修飾免疫細胞の生存及び増加を特異的に刺激するための方法
CN118546959A (zh) 2019-03-05 2024-08-27 恩卡尔塔公司 Cd19定向性嵌合抗原受体及其在免疫疗法中的用途
EP3934617A1 (de) 2019-03-08 2022-01-12 Boehringer Ingelheim International GmbH Anti-il-36r-antikörperformulierungen
EP4182022A1 (de) 2020-07-17 2023-05-24 Boehringer Ingelheim International GmbH Anti-il-36r-antikörper zur behandlung neutrophiler dermatosen

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US4859609A (en) 1986-04-30 1989-08-22 Genentech, Inc. Novel receptors for efficient determination of ligands and their antagonists or agonists
CA2247207A1 (en) * 1995-02-28 1996-09-06 National Jewish Center For Immunology And Respiratory Medicine Peptidyl compounds comprising an itim motif which regulate hematopoietic function and their use
WO1997020046A1 (en) * 1995-11-30 1997-06-05 Schering Corporation Dnam, an nk antigen and adhesion molecule of the immunoglobulin superfamily
WO1998039446A2 (en) * 1997-03-07 1998-09-11 Human Genome Sciences, Inc. 70 human secreted proteins
WO1999002546A1 (en) * 1997-07-08 1999-01-21 Human Genome Sciences, Inc. 123 human secreted proteins
JP2002503094A (ja) * 1997-04-30 2002-01-29 アンスティテュ ナシオナル ドゥ ラ サーント エ ドゥ ラ ルシェルシュ メディカル(イ エン エス ウ エル エム) 活性化レセプタに会合される新しいポリペプチド及びその生物学的応用
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Also Published As

Publication number Publication date
DE69836082D1 (de) 2006-11-16
JP2010099077A (ja) 2010-05-06
JP2010099076A (ja) 2010-05-06
EP1798287A2 (de) 2007-06-20
EP1003861A2 (de) 2000-05-31
EP1798286B1 (de) 2011-09-07
JP2001512017A (ja) 2001-08-21
ES2274574T3 (es) 2007-05-16
EP1798286A2 (de) 2007-06-20
JP4855513B2 (ja) 2012-01-18
EP1798286A3 (de) 2007-11-14
EP1003861B1 (de) 2006-10-04
WO1999006557A2 (en) 1999-02-11
AU8661498A (en) 1999-02-22
PT1003861E (pt) 2007-01-31
ATE523593T1 (de) 2011-09-15
WO1999006557A3 (en) 1999-05-20
EP1798287A3 (de) 2007-11-14
DE69836082T2 (de) 2007-05-10

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