ATE340575T1 - Vorbeugung und behandlung von krankheiten in zusammenhang zu vaskularen funktionellen stoerungen un verbindung mit insulinresistenz - Google Patents
Vorbeugung und behandlung von krankheiten in zusammenhang zu vaskularen funktionellen stoerungen un verbindung mit insulinresistenzInfo
- Publication number
- ATE340575T1 ATE340575T1 AT99906501T AT99906501T ATE340575T1 AT E340575 T1 ATE340575 T1 AT E340575T1 AT 99906501 T AT99906501 T AT 99906501T AT 99906501 T AT99906501 T AT 99906501T AT E340575 T1 ATE340575 T1 AT E340575T1
- Authority
- AT
- Austria
- Prior art keywords
- insulin resistance
- prevention
- treatment
- diseases
- functional disorders
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 4
- 206010022489 Insulin Resistance Diseases 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title abstract 3
- 208000001072 type 2 diabetes mellitus Diseases 0.000 title abstract 3
- 230000002265 prevention Effects 0.000 title 1
- 230000002792 vascular Effects 0.000 title 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 230000006492 vascular dysfunction Effects 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP04772098A JP4306825B2 (ja) | 1998-02-27 | 1998-02-27 | インスリン抵抗性が関与する血管機能異常を伴う疾患の予防または治療剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE340575T1 true ATE340575T1 (de) | 2006-10-15 |
Family
ID=12783164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99906501T ATE340575T1 (de) | 1998-02-27 | 1999-02-26 | Vorbeugung und behandlung von krankheiten in zusammenhang zu vaskularen funktionellen stoerungen un verbindung mit insulinresistenz |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6410535B1 (de) |
| EP (1) | EP0983765B1 (de) |
| JP (1) | JP4306825B2 (de) |
| AT (1) | ATE340575T1 (de) |
| DE (1) | DE69933347T2 (de) |
| DK (1) | DK0983765T3 (de) |
| ES (1) | ES2272052T3 (de) |
| PT (1) | PT983765E (de) |
| WO (1) | WO1999043325A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7442372B2 (en) | 2003-08-29 | 2008-10-28 | Biomarin Pharmaceutical Inc. | Delivery of therapeutic compounds to the brain and other tissues |
| PL1708690T3 (pl) | 2003-11-17 | 2017-01-31 | Biomarin Pharmaceutical Inc. | Leczenie fenyloketonurii za pomocą BH4 |
| MX2007005039A (es) | 2004-11-17 | 2007-06-19 | Biomarin Pharm Inc | Formulacion de tableta estable. |
| EP1819340A2 (de) * | 2004-12-08 | 2007-08-22 | Biomarin Pharmaceutical Inc. | Verfahren und zusammensetzungen zur behandlung von lungenhypertonie bei neugeborenen |
| TW200719896A (en) * | 2005-04-18 | 2007-06-01 | Astrazeneca Ab | Combination product |
| EP1965803A1 (de) * | 2005-12-05 | 2008-09-10 | Biomarin Pharmaceutical Inc. | Verfahren und zusammensetzungen zur behandlung von krankheiten |
| EP2114944A2 (de) * | 2007-01-12 | 2009-11-11 | BioMarin Pharmaceutical Inc. | Tetrahydrobiopterin-prodrugs |
| US20100009997A1 (en) * | 2007-01-12 | 2010-01-14 | Biomarin Pharmaceutical Inc. | Method of treating a metabolic or neuropsychiarty disorder with a bh4 derivative prodrug |
| LT2545939T (lt) | 2007-04-11 | 2021-03-10 | Biomarin Pharmaceutical Inc. | Tetrahidrobiopterinas, skirtas gydyti ligas, susijusias supadidėjusiu fenilalanino kiekiu |
| JP2011508775A (ja) * | 2008-01-03 | 2011-03-17 | ビオマリン プハルマセウトイカル インコーポレイテッド | Ｂｈ４応答性状態を治療するためのプテリン類似体 |
| JP5559656B2 (ja) * | 2010-10-14 | 2014-07-23 | 大日本スクリーン製造株式会社 | 熱処理装置および熱処理方法 |
| US9216178B2 (en) | 2011-11-02 | 2015-12-22 | Biomarin Pharmaceutical Inc. | Dry blend formulation of tetrahydrobiopterin |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5925323A (ja) | 1982-03-03 | 1984-02-09 | 鐘淵化学工業株式会社 | プテリン誘導体からなる脳内神経伝達物質の関わる疾病の治療剤 |
| JPS5976086A (ja) | 1982-09-20 | 1984-04-28 | ザ ウエルカム フアウンデ−シヨン リミテツド | プテリジン化合物 |
| AU572792B2 (en) | 1982-09-20 | 1988-05-19 | Wellcome Foundation Limited, The | 2-amino, 4-oxo-pteridine derivatives |
| JPS61277618A (ja) * | 1985-06-04 | 1986-12-08 | Suntory Ltd | 自閉症治療剤 |
| JP2588191B2 (ja) * | 1987-04-24 | 1997-03-05 | サントリー株式会社 | 悪性腫瘍および重症ウイルス感染症に伴う神経症状を改善するための治療剤 |
| JPH0656669A (ja) * | 1992-06-11 | 1994-03-01 | Asahi Breweries Ltd | 活性酸素消去作用を持つプテリン誘導体製剤 |
| ES2177654T3 (es) | 1994-08-05 | 2002-12-16 | Suntory Ltd | Remedio contra la degeneracion espinocerebelosa. |
-
1998
- 1998-02-27 JP JP04772098A patent/JP4306825B2/ja not_active Expired - Lifetime
-
1999
- 1999-02-26 PT PT99906501T patent/PT983765E/pt unknown
- 1999-02-26 WO PCT/JP1999/000917 patent/WO1999043325A1/ja not_active Ceased
- 1999-02-26 DK DK99906501T patent/DK0983765T3/da active
- 1999-02-26 ES ES99906501T patent/ES2272052T3/es not_active Expired - Lifetime
- 1999-02-26 AT AT99906501T patent/ATE340575T1/de active
- 1999-02-26 EP EP99906501A patent/EP0983765B1/de not_active Expired - Lifetime
- 1999-02-26 DE DE69933347T patent/DE69933347T2/de not_active Expired - Lifetime
- 1999-10-27 US US09/427,579 patent/US6410535B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6410535B1 (en) | 2002-06-25 |
| DK0983765T3 (da) | 2007-01-02 |
| EP0983765A4 (de) | 2001-04-04 |
| PT983765E (pt) | 2006-12-29 |
| ES2272052T3 (es) | 2007-04-16 |
| EP0983765A1 (de) | 2000-03-08 |
| DE69933347T2 (de) | 2007-05-03 |
| EP0983765B1 (de) | 2006-09-27 |
| US20020082261A1 (en) | 2002-06-27 |
| DE69933347D1 (de) | 2006-11-09 |
| JP4306825B2 (ja) | 2009-08-05 |
| JPH11246410A (ja) | 1999-09-14 |
| WO1999043325A1 (fr) | 1999-09-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0908182A4 (de) | Vorbeugende oder heilende mittel für krankheiten, die durch mangel an stickoxid-synthase (nos) ausgelöst ist | |
| ATE375341T1 (de) | Thiadiazolylpiperazinderivate geeignet für die behandlung bzw. prävention von schmerzen | |
| CY1111951T1 (el) | Φαινυλο-καρβοξαμιδικες ενωσεις χρησιμες για την αντιμετωπιση πονου | |
| WO2005056524A3 (en) | Therapeutic agents useful for treating pain | |
| IL148384A0 (en) | Glucopyranosyloxypyrazole derivatives, medicinal compositions containing the same and intermediates in the production thereof | |
| TW200642685A (en) | Novel spiroindoline or spiroisoquinoline compounds, methods of use and compositions thereof | |
| ES2165969T3 (es) | Compuestos nitrogenados aromaticos condensados 5,5 aril-sustituidos como agentes antiinflamatorios. | |
| WO2004029031A3 (en) | Therapeutic piperazine compounds | |
| ATE340575T1 (de) | Vorbeugung und behandlung von krankheiten in zusammenhang zu vaskularen funktionellen stoerungen un verbindung mit insulinresistenz | |
| CA2301742A1 (en) | 2,3,5-trisubstituted pyridines as inhibitors of cyclooxygenase-2 | |
| CA2283399A1 (en) | Pyridazinones as inhibitors of cyclooxygenase-2 | |
| AU4396899A (en) | Remedies for diabetes | |
| ATE181553T1 (de) | Kondensierte thiazolverbindungen, ihre darstellung und ihre anwendung | |
| DK0659427T3 (da) | 2-Phenyl-3-azoylbenzothiophener til forøgelse af thrombomodulinekspression | |
| RU94045271A (ru) | Применение 2-фенил-3-ароилбензотиофенов для ингибирования синдрома тернера | |
| CA2211320A1 (en) | 5-methanesulfonamido-3h-isobenzofuran-1-ones as inhibitors of cyclooxygenase-2 | |
| DE69925225D1 (de) | Propylaxe und behandlung der arzneimittel induzierten nierenstörungen | |
| IL148196A0 (en) | Heterocyclic compounds and pharmaceutical compositions containing the same | |
| DE69518706D1 (de) | Verwendung von Diphenylethanderivaten zur Herstellung eines Arzneimittels zur Behandlung von Glaukom | |
| UA66751C2 (en) | Benzamides as medicament for treatment of neurodegenerative state, a method for the preparation thereof (variants), pharnaceutical composition for treatment of neurodegenerative states and a method for treatment | |
| DE69722630D1 (de) | Therapeutisches mittel zur behandlung von nierenerkrankungen | |
| DE69424677D1 (de) | Präparat zur behandlung der drogenabhängigkeit | |
| CA2236078A1 (en) | Prophylactic or therapeutic agents for diseases associated with dysfunction of nos | |
| TH19066A (th) | วิธีสำหรับยับยั้งการเพิ่มจำนวนเซลล์กล้ามเนื้อเรียบและภาวะการตีบของหลอดเลือด | |
| EA200601270A1 (ru) | Новые индено[2,1-a]индены и изоиндоло[2,1-a]индолы |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0983765 Country of ref document: EP |