ATE228123T1 - Thiophennitronderivate - Google Patents

Thiophennitronderivate

Info

Publication number: ATE228123T1
Authority: AT; Austria
Prior art keywords: thiophennitron; derivatives; disclosed; compounds; therapeutics
Prior art date: 1998-01-16

Application number

AT99902243T

Other languages

English (en)

Inventor

Judith A Kelleher

Kirk R Maples

Yong-Kang Zhang

Original Assignee

Centaur Pharmaceuticals Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-01-16

Filing date

1999-01-14

Publication date

2002-12-15

1999-01-14 Application filed by Centaur Pharmaceuticals Inc filed Critical Centaur Pharmaceuticals Inc

2002-12-15 Application granted granted Critical

2002-12-15 Publication of ATE228123T1 publication Critical patent/ATE228123T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Psychology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Semiconductor Lasers (AREA)
Automatic Cycles, And Cycles In General (AREA)

AT99902243T 1998-01-16 1999-01-14 Thiophennitronderivate ATE228123T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US7279098P	1998-01-16	1998-01-16
PCT/US1999/000786 WO1999036420A1 (en)	1998-01-16	1999-01-14	Thiophene nitrone compounds

Publications (1)

Publication Number	Publication Date
ATE228123T1 true ATE228123T1 (de)	2002-12-15

Family

ID=22109769

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99902243T ATE228123T1 (de)	1998-01-16	1999-01-14	Thiophennitronderivate

Country Status (10)

Country	Link
US (1)	US6015831A (de)
EP (1)	EP1047688B1 (de)
JP (1)	JP2002509147A (de)
CN (1)	CN1136212C (de)
AT (1)	ATE228123T1 (de)
AU (1)	AU2226999A (de)
CA (1)	CA2318555A1 (de)
DE (1)	DE69904018D1 (de)
WO (1)	WO1999036420A1 (de)
ZA (1)	ZA99255B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE267804T1 (de)	1998-07-17	2004-06-15	Renovis Inc	Alpha-(2-hydroxyphenyl)nitrone, diese enthaltenden pharmazeutische zubereitungen sowie deren verwendung zur behandlung von entzündungen
UA66401C2 (en)	1998-12-02	2004-05-17	Sentor Pharmaceuticals Inc	3,4,5-trisubstituted aryl nitrone compounds and pharmaceutical composition containing the same
US6730700B2 (en)	1998-12-02	2004-05-04	Renovis, Inc.	3,4,5,-trisubstituted aryl nitrone compounds and pharmaceutical compositions containing the same
DE10043282A1 (de) *	2000-09-02	2002-03-28	Kurt Heininger	Verwendung von Inhibitoren der Amyloid-beta-Protein-Bildung
US20050059638A1 (en) *	2003-08-04	2005-03-17	Kelly Michael G.	Aryl, heteroaromatic and bicyclic aryl nitrone compounds, prodrugs and pharmaceutical compositions of the same to treat human disorders
US20050182060A1 (en) *	2004-02-13	2005-08-18	Kelly Michael G.	2-Substituted and 4-substituted aryl nitrone compounds
CN101468970B (zh)	2008-04-25	2011-05-11	暨南大学	一种硝酮类化合物及其制备方法和在制药中的应用

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3666754A (en) *	1965-11-06	1972-05-30	Dainippon Pharmaceutical Co	2-(5-nitrofuryl) nitrone derivatives
US3988159A (en) *	1967-07-28	1976-10-26	American Can Company	Light-sensitive material containing nitrone for forming heat-fixed images
US3849934A (en) *	1971-05-03	1974-11-26	Scm Corp	Alpha-aryl-n-lower alkyl nitrone-containing compositions useful as anti-fungal agents
US3834073A (en) *	1971-05-03	1974-09-10	Scm Corp	Phenyl nitrone derivatives useful as seed protectants
US3950327A (en) *	1972-09-19	1976-04-13	Ciba-Geigy Corporation	New nitrones, their manufacture and their use for the manufacture of n-substituted araliphatic aldehyde-nitrones
US3903049A (en) *	1974-01-30	1975-09-02	Goodyear Tire & Rubber	Oxidation resistant sulfur curable rubbery polymers
US3917700A (en) *	1974-01-30	1975-11-04	Goodyear Tire & Rubber	Nitrone compounds
GB1588417A (en) *	1977-03-15	1981-04-23	Agfa Gevaert	Photoresist materials
US4153722A (en) *	1977-10-06	1979-05-08	William H. Rorer, Inc.	Method of treatment
GB2137619A (en) *	1983-03-30	1984-10-10	Gerald Scott	Nitrone compounds and stabilised rubber compositions containing them
US5352442A (en) *	1985-07-18	1994-10-04	Proctor Peter H	Topical tempo
US5723502A (en) *	1985-07-18	1998-03-03	Proctor; Peter H.	Topical spin trap composition and method
DE3785694T2 (de) *	1986-05-13	1993-09-16	Seitetsu Kagaku Co Ltd	Thiophenderivate und verfahren zu ihrer herstellung.
US4871862A (en) *	1986-08-27	1989-10-03	Fisons Corporation	α-Substituted ketonitrone derivatives
US4803282A (en) *	1986-08-27	1989-02-07	Pennwalt Corporation	Alpha-substituted ketonitrone derivatives
ATE110954T1 (de) *	1988-01-29	1994-09-15	Peter H Proctor	Haarwachstumanregung mit nitroxyd und anderen radikalen.
HK1007281A1 (en) *	1989-10-17	1999-04-09	Oklahoma Medical Research Foundation	Method and compositions for inhibition of disorders associated with oxidative damage
DE69232263T2 (de) *	1991-06-18	2003-06-18	Oklahoma Medical Research Foundation, Oklahoma	Radikalfänger ("spin traps") zur behandlung von mit oxidation von lipiden und proteinen verbundenen erkrankungen
US5292746A (en) *	1991-09-12	1994-03-08	Merrell Dow Pharmaceuticals Inc.	Cyclic nitrones, pharmaceutical compositions thereof and their use in treating shock
GB9300894D0 (en) *	1992-02-07	1993-03-10	Zeneca Ltd	Oxime derivatives
US5455272A (en) *	1993-10-22	1995-10-03	Oklahoma Medical Research Foundation	Spin trap nitronyl hindered phenols
US5488145A (en) *	1993-12-23	1996-01-30	Oklahoma Medical Research Foundation	2,4-disulfonyl phenyl butyl nitrone, its salts, and their use as pharmaceutical free radical traps
ES2239194T3 (es) *	1995-09-11	2005-09-16	Aventis Pharmaceuticals Inc.	Nitronas ciclicas y composiciones farmaceuticas que las contienen.
EP0888290B1 (de) *	1995-11-17	2006-12-27	Florida International University	Azulenylnitrone als radikal fanger (spin trapping agents), verfahren zu ihrer herstellung und ihre anwendung
WO1998003496A1 (en) *	1996-07-19	1998-01-29	Centaur Pharmaceuticals, Inc.	Furan nitrone compounds
TW429241B (en) *	1996-09-26	2001-04-11	Sumitomo Pharma	Nitrone derivatives

1999
- 1999-01-14 ZA ZA9900255A patent/ZA99255B/xx unknown
- 1999-01-14 EP EP99902243A patent/EP1047688B1/de not_active Expired - Lifetime
- 1999-01-14 US US09/245,126 patent/US6015831A/en not_active Expired - Fee Related
- 1999-01-14 AT AT99902243T patent/ATE228123T1/de not_active IP Right Cessation
- 1999-01-14 WO PCT/US1999/000786 patent/WO1999036420A1/en not_active Ceased
- 1999-01-14 DE DE69904018T patent/DE69904018D1/de not_active Expired - Lifetime
- 1999-01-14 AU AU22269/99A patent/AU2226999A/en not_active Abandoned
- 1999-01-14 CN CNB998033014A patent/CN1136212C/zh not_active Expired - Fee Related
- 1999-01-14 JP JP2000540136A patent/JP2002509147A/ja not_active Withdrawn
- 1999-01-14 CA CA002318555A patent/CA2318555A1/en not_active Abandoned

Also Published As

Publication number	Publication date
JP2002509147A (ja)	2002-03-26
DE69904018D1 (en)	2003-01-02
CA2318555A1 (en)	1999-07-22
ZA99255B (en)	1999-07-14
EP1047688B1 (de)	2002-11-20
EP1047688A1 (de)	2000-11-02
AU2226999A (en)	1999-08-02
US6015831A (en)	2000-01-18
WO1999036420A1 (en)	1999-07-22
CN1291981A (zh)	2001-04-18
CN1136212C (zh)	2004-01-28

Publication	Publication Date	Title
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ATE297898T1 (de)	2005-07-15	4-carboxamino-2-subsitutierte-1,2,3,4- tetrahydrochinoline als cetp inhibitoren
ATE277906T1 (de)	2004-10-15	4-carboxamino-2-methyl-1,2,3,4- tetrahydrochinoline als cetp inhibitoren
ATE273345T1 (de)	2004-08-15	Polymerzusammensetzung für rohre
BR9903578B1 (pt)	2009-01-13	composiÇÕes de toner.
FI964087A7 (fi)	1996-10-11	Housuvaippa tai housuside
PT842934E (pt)	2004-03-31	Agonistas de 5-ht1f
ID22562A (id)	1999-11-11	Komposisi untuk pembasmi artropoda berbahaya
AU8330898A (en)	1998-11-27	Substituted heterocycles and their use in medicaments
TR199801954T2 (xx)	1998-12-21	Eprosartan dihidrat ve �retimi ve form�lasyonu i�in bir proses.
DE59901345D1 (de)	2002-06-06	Sortieranlage für flaches postgut
TR200100462T2 (tr)	2001-09-21	Muskarinik agonistleri ve antagonistleri
DE10293802D2 (de)	2004-11-04	Gebäude und Parksystem
ATE387448T1 (de)	2008-03-15	4,5-pyrazinoxindole als proteinkinasehemmer
DE69104613D1 (de)	1994-11-17	Neues in-line-rheometer für polymerschmelzen.
ATE228123T1 (de)	2002-12-15	Thiophennitronderivate
FI942852A0 (fi)	1994-06-15	Stabiloituja polymeerikoostumuksia
DE69707098D1 (de)	2001-11-08	Substituierte tetralylmethylenoxindol-analoga als tyrosinkinase-inhibitoren
PT1054867E (pt)	2004-09-30	Antivirais
DE69917643D1 (de)	2004-07-01	Alpha-(2-hydroxyphenyl)nitrone, diese enthaltenden pharmazeutische zubereitungen sowie deren verwendung zur behandlung von entzündungen
FI981298L (fi)	1999-12-06	Polymeerikoostumukset
DK0933637T3 (da)	2004-09-06	Prænatal påvisning af kromosomabnormitet
FR2717821B1 (fr)	1998-11-20	Compositions de polymères chlorés stabilisées.
DE69626081D1 (de)	2003-03-13	Antistatisches Hilfsmittel für Polymerzusammensetzungen

Legal Events

Date	Code	Title	Description
2003-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties