ATE227992T1 - Behandlungsverfahren zur förderung des gewichtsverlustes unter verwendung eines substituierten delta-5-androstens - Google Patents
Behandlungsverfahren zur förderung des gewichtsverlustes unter verwendung eines substituierten delta-5-androstensInfo
- Publication number
- ATE227992T1 ATE227992T1 AT91917276T AT91917276T ATE227992T1 AT E227992 T1 ATE227992 T1 AT E227992T1 AT 91917276 T AT91917276 T AT 91917276T AT 91917276 T AT91917276 T AT 91917276T AT E227992 T1 ATE227992 T1 AT E227992T1
- Authority
- AT
- Austria
- Prior art keywords
- androstene
- delta
- weight loss
- beta
- promoting
- Prior art date
Links
- 230000001737 promoting effect Effects 0.000 title abstract 5
- 230000004580 weight loss Effects 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 2
- NXQOQNROJJFYCJ-FZFXZXLVSA-N androst-16-ene Chemical compound C1CCC[C@]2(C)[C@H]3CC[C@](C)(C=CC4)[C@@H]4[C@@H]3CCC21 NXQOQNROJJFYCJ-FZFXZXLVSA-N 0.000 title 1
- 230000004584 weight gain Effects 0.000 abstract 3
- 235000019786 weight gain Nutrition 0.000 abstract 3
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- OSVMTWJCGUFAOD-KZQROQTASA-N formestane Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1O OSVMTWJCGUFAOD-KZQROQTASA-N 0.000 abstract 1
- 239000003163 gonadal steroid hormone Substances 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 238000004260 weight control Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pretreatment Of Seeds And Plants (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Signal Processing For Digital Recording And Reproducing (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Developing Agents For Electrophotography (AREA)
- Disintegrating Or Milling (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57515690A | 1990-08-29 | 1990-08-29 | |
| PCT/US1991/006147 WO1992003925A1 (en) | 1990-08-29 | 1991-08-28 | Treatment process for promoting weight loss employing a substituted δ5-androstene |
| US43981603P | 2003-01-13 | 2003-01-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE227992T1 true ATE227992T1 (de) | 2002-12-15 |
Family
ID=37772553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91917276T ATE227992T1 (de) | 1990-08-29 | 1991-08-28 | Behandlungsverfahren zur förderung des gewichtsverlustes unter verwendung eines substituierten delta-5-androstens |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5296481A (de) |
| EP (1) | EP0547151B1 (de) |
| JP (1) | JP2973031B2 (de) |
| AT (1) | ATE227992T1 (de) |
| AU (1) | AU647528B2 (de) |
| CA (1) | CA2090759A1 (de) |
| DE (1) | DE69133158T2 (de) |
| DK (1) | DK0547151T3 (de) |
| ES (1) | ES2184729T3 (de) |
| WO (2) | WO1992003925A1 (de) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5641768A (en) * | 1989-11-17 | 1997-06-24 | Loria; Roger M. | 5-androstene 3β, 17β diol for treatment |
| WO1992003925A1 (en) * | 1990-08-29 | 1992-03-19 | Humanetics Corporation | Treatment process for promoting weight loss employing a substituted δ5-androstene |
| US5807848A (en) * | 1990-08-29 | 1998-09-15 | Humanetics Corporation | Use of dehydroepeiandrosterone-3-carboxylates to control body weight |
| FR2696934B1 (fr) * | 1992-10-20 | 1995-06-02 | Conservatoire Nal Arts Metiers | Dérivés de stéroïdes naturels 3B hydroxyles ayant des propriétés de déclenchement et de stimulation de l'immunité, composition les contenant et procédé pour les obtenir. |
| CA2148373A1 (en) * | 1993-09-02 | 1995-03-09 | Henry A. Lardy | Delta 5-androstenes useful for promoting weight maintenance or weight loss and treatment process |
| WO1995010527A1 (en) * | 1993-10-13 | 1995-04-20 | Neurocrine Biosciences, Inc. | 3,17-dihydroxy-3,7,16 and/or 17-methyl-androst-5-ene compounds, derivatives thereof, and their use |
| WO1997037664A2 (en) | 1996-04-09 | 1997-10-16 | British Technology Group Ltd. | Use of 7 alpha-substituted steroids to treat neuropsychiatric, immune or endocrine disorders |
| US6686486B1 (en) | 1997-05-07 | 2004-02-03 | Padma Marwah | Process for effecting allylic oxidation |
| US5869709A (en) * | 1997-05-07 | 1999-02-09 | Humanetics Corporation | Process for effecting allylic oxidation |
| US6252119B1 (en) * | 1997-07-28 | 2001-06-26 | Salvador Jorge Antonio Riberiro | Copper-catalysed allylic oxidation using alkyl hydroperoxide |
| AU8779898A (en) * | 1997-08-11 | 1999-03-01 | Weider Nutrition International, Inc. | Compositions and treatments to reduce side effects of administration of androgenic testosterone precursors |
| US6372732B1 (en) * | 1997-11-19 | 2002-04-16 | Humanetics Corporation | Use of delta5-androstene-3beta-ol-7, 17-dione in the treatment of lupus erythematosus |
| WO1999047485A1 (en) | 1998-03-18 | 1999-09-23 | Humanetics Corporation | Process for effecting allylic oxidation using dicarboxylic acid imides and chromium reagents |
| US6153606A (en) | 1998-10-16 | 2000-11-28 | Humanetics Corporation | Memory enhancement by the administration of Δ5-androstene-3β-ol-7,17-dione and 3β esters thereof |
| US6667299B1 (en) * | 2000-03-16 | 2003-12-23 | Hollis-Eden Pharmaceuticals, Inc. | Pharmaceutical compositions and treatment methods |
| US20070129282A1 (en) * | 1998-11-24 | 2007-06-07 | Ahlem Clarence N | Pharmaceutical treatments and compositions |
| FR2793491B1 (fr) * | 1999-05-10 | 2005-01-21 | Mayoly Spindler Lab | Procede de synthese stereospecifique par oxydation allylique de composes allyliques |
| DE60045751D1 (de) * | 1999-09-30 | 2011-04-28 | Harbor Biosciences Inc | Therapeutische Behandlung androgenrezeptorbedingter Leiden |
| WO2002043737A1 (en) * | 2000-11-30 | 2002-06-06 | Humanetics Corporation | Treatment of chronic fatigue syndrome and fibromyalgia syndrome |
| FR2818135B1 (fr) | 2000-12-15 | 2003-02-14 | Oreal | Composition, notamment cosmetique, renfermant la 7-hydroxy dhea et/ou la 7-ceto dhea et au moins un carotenoide |
| FR2818148B1 (fr) | 2000-12-15 | 2005-06-24 | Oreal | Composition,notamment cosmetique, renfermant, la 7-hydroxy dhea et/ou la 7-ceto dhea et au moins un isoflavonoide |
| FR2820745A1 (fr) * | 2001-02-14 | 2002-08-16 | Oreal | Procedes de preparation de la 7alpha-hydroxy- dehydroepiandrosterone |
| US6399085B1 (en) | 2001-03-05 | 2002-06-04 | Humanetics Corporation | Method of moisturizing the skin by the topical application of Δ5-androstene-3β-ol-7,17 dione and metabolizable precursors thereof |
| US6399084B1 (en) | 2001-03-05 | 2002-06-04 | Humanetics Corporation | Method for diminishing wrinkles and fine lines of the skin by the topical application of Δ5-androstene-3β-ol-7, 17 dione and metabolizable precursors thereof |
| US6465446B1 (en) | 2001-03-12 | 2002-10-15 | John C. Dykstra | Treatment of dermatitis by the topical application of Δ5-androstene-3β-ol-7,17 dione and metabolizable precursors thereof |
| US6368617B1 (en) | 2001-05-15 | 2002-04-09 | Reliv' International, Inc. | Dietary supplement |
| US6746182B2 (en) * | 2001-07-27 | 2004-06-08 | Abb Vetco Gray Inc. | Keel joint arrangements for floating platforms |
| FR2830015A1 (fr) * | 2001-09-27 | 2003-03-28 | Berkem Sa | Compositions a base de derives de steroides |
| US20060217357A1 (en) * | 2003-01-13 | 2006-09-28 | Humanetics Corporation | Method of achieving accelerated fat loss by administration of a fat loss accelerating agent to a dieting mammal |
| US20060135499A1 (en) * | 2003-01-13 | 2006-06-22 | Zenk John L | Method of achieving accelerated weight loss by administration of a weight loss accelerating agent to a dieting mammal |
| US7199116B2 (en) * | 2003-01-13 | 2007-04-03 | Humanetics Corporation | Method of modulating the basal metabolic rate of a dieting mammal by administration of a metabolic modulating agent to the dieting mammal |
| US20040242618A1 (en) * | 2003-04-01 | 2004-12-02 | Lardy Henry A. | Antiandrogens with marginal agonist activity and methods of use |
| US20050069593A1 (en) * | 2003-09-29 | 2005-03-31 | Life Time Fitness, Inc. | Nutritional supplement containing 7-Keto-DHEA and conjugated linoleic acid |
| FR2882556B1 (fr) | 2005-02-28 | 2007-05-04 | Servier Lab | Forme cristalline gamma d du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
| FR2882553B1 (fr) | 2005-02-28 | 2007-05-04 | Servier Lab | Forme cristalline beta du chlorhydrate de l'ivabradine, son procede de preparation, et les compositions pharmaceutiques qui la contiennent |
| US20080153792A1 (en) * | 2006-11-17 | 2008-06-26 | Frincke James M | Drug Identification and Treatment Method |
| US20080221074A1 (en) * | 2006-11-17 | 2008-09-11 | Jaime Flores-Riveros | Drug Screen and Treatment Method |
| US8217025B2 (en) * | 2006-11-17 | 2012-07-10 | Harbor Therapeutics, Inc. | Drug screening and treatment methods |
| US8486926B2 (en) * | 2006-11-17 | 2013-07-16 | Harbor Therapeutics, Inc. | Steroid tetrol solid state forms |
| US8354396B2 (en) * | 2006-11-17 | 2013-01-15 | Harbor Therapeutics, Inc. | Drug identification and treatment method |
| JP2011527986A (ja) * | 2008-04-03 | 2011-11-10 | ハーバー バイオサイエンシーズ,インコーポレイテッド | 医薬の固体状態形態 |
| US20100227841A1 (en) * | 2008-09-24 | 2010-09-09 | Harbor BioSciencs, Inc. | Patient populations and treatment methods |
| US20100222315A1 (en) * | 2008-09-24 | 2010-09-02 | Harbor BioSciencs, Inc. | Patient populations and treatment methods |
| US20100075937A1 (en) * | 2008-09-24 | 2010-03-25 | Hollis-Eden Pharmaceuticals, Inc. | Patient populations and treatment methods |
| US20110129423A1 (en) * | 2009-11-30 | 2011-06-02 | Frincke James M | Anticancer compounds and screening method |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4217353A (en) * | 1978-05-19 | 1980-08-12 | E. I. Du Pont De Nemours And Company | Method for inducing anorexia |
| US4511511A (en) * | 1982-12-15 | 1985-04-16 | Crozer-Chester Medical Center | Prednisolone derivatives |
| US4518595A (en) * | 1983-07-19 | 1985-05-21 | The Jackson Laboratory | Method for treating diabetes using DHEA compounds |
| IL72566A (en) * | 1983-08-02 | 1988-08-31 | Research Corp | Androst-5-en-17-one and 5alpha-androstan-17-one derivatives and pharmaceutical compositions containing the same |
| DE3418491A1 (de) * | 1984-05-18 | 1985-11-21 | Merck Patent Gmbh, 6100 Darmstadt | Diaminosaeurederivate |
| AU601184B2 (en) * | 1986-05-21 | 1990-09-06 | Research Corporation | Steroids useful as anti-cancer and anti-obesity agents |
| US4897390A (en) * | 1987-07-21 | 1990-01-30 | Ruhe Rodney C | Novel anti-obesity compounds and method of use |
| US4898694A (en) * | 1987-11-25 | 1990-02-06 | Schwartz Arthur G | 17-Hydroxy-steroids |
| WO1992003925A1 (en) * | 1990-08-29 | 1992-03-19 | Humanetics Corporation | Treatment process for promoting weight loss employing a substituted δ5-androstene |
-
1991
- 1991-08-28 WO PCT/US1991/006147 patent/WO1992003925A1/en active IP Right Grant
- 1991-08-28 CA CA002090759A patent/CA2090759A1/en not_active Abandoned
- 1991-08-28 ES ES91917276T patent/ES2184729T3/es not_active Expired - Lifetime
- 1991-08-28 DK DK91917276T patent/DK0547151T3/da active
- 1991-08-28 AU AU85418/91A patent/AU647528B2/en not_active Ceased
- 1991-08-28 EP EP91917276A patent/EP0547151B1/de not_active Expired - Lifetime
- 1991-08-28 JP JP3515665A patent/JP2973031B2/ja not_active Expired - Fee Related
- 1991-08-28 AT AT91917276T patent/ATE227992T1/de not_active IP Right Cessation
- 1991-08-28 DE DE69133158T patent/DE69133158T2/de not_active Expired - Fee Related
-
1992
- 1992-04-10 US US07/867,288 patent/US5296481A/en not_active Expired - Lifetime
-
2004
- 2004-01-12 WO PCT/US2004/000541 patent/WO2004062606A2/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| AU8541891A (en) | 1992-03-30 |
| AU647528B2 (en) | 1994-03-24 |
| WO2004062606A3 (en) | 2004-11-25 |
| CA2090759A1 (en) | 1992-03-01 |
| DE69133158D1 (de) | 2003-01-02 |
| EP0547151A1 (de) | 1993-06-23 |
| JPH06508345A (ja) | 1994-09-22 |
| WO1992003925A1 (en) | 1992-03-19 |
| JP2973031B2 (ja) | 1999-11-08 |
| US5296481A (en) | 1994-03-22 |
| ES2184729T3 (es) | 2003-04-16 |
| DE69133158T2 (de) | 2003-07-17 |
| DK0547151T3 (da) | 2003-03-17 |
| EP0547151B1 (de) | 2002-11-20 |
| EP0547151A4 (en) | 1993-10-13 |
| WO2004062606A2 (en) | 2004-07-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0547151 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |