[go: up one dir, main page]

ATE210191T1 - Nukleotid-sequenzierungsmethode - Google Patents

Nukleotid-sequenzierungsmethode

Info

Publication number
ATE210191T1
ATE210191T1 AT95929169T AT95929169T ATE210191T1 AT E210191 T1 ATE210191 T1 AT E210191T1 AT 95929169 T AT95929169 T AT 95929169T AT 95929169 T AT95929169 T AT 95929169T AT E210191 T1 ATE210191 T1 AT E210191T1
Authority
AT
Austria
Prior art keywords
nucleotide
pct
target sample
primers
ddntps
Prior art date
Application number
AT95929169T
Other languages
English (en)
Inventor
Gillian Tully
Kevin Sullivan
Original Assignee
Sec Dep Home Dept
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sec Dep Home Dept filed Critical Sec Dep Home Dept
Application granted granted Critical
Publication of ATE210191T1 publication Critical patent/ATE210191T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6858Allele-specific amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
AT95929169T 1994-08-25 1995-08-21 Nukleotid-sequenzierungsmethode ATE210191T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9417211A GB9417211D0 (en) 1994-08-25 1994-08-25 Nucleotide sequencing method
PCT/GB1995/001987 WO1996006187A1 (en) 1994-08-25 1995-08-21 Nucleotide sequencing method

Publications (1)

Publication Number Publication Date
ATE210191T1 true ATE210191T1 (de) 2001-12-15

Family

ID=10760409

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95929169T ATE210191T1 (de) 1994-08-25 1995-08-21 Nukleotid-sequenzierungsmethode

Country Status (10)

Country Link
US (1) US5925520A (de)
EP (1) EP0777747B1 (de)
AT (1) ATE210191T1 (de)
AU (1) AU3263095A (de)
DE (1) DE69524425T2 (de)
DK (1) DK0777747T3 (de)
ES (1) ES2169143T3 (de)
GB (1) GB9417211D0 (de)
PT (1) PT777747E (de)
WO (1) WO1996006187A1 (de)

Families Citing this family (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605798A (en) * 1993-01-07 1997-02-25 Sequenom, Inc. DNA diagnostic based on mass spectrometry
US7803529B1 (en) 1995-04-11 2010-09-28 Sequenom, Inc. Solid phase sequencing of biopolymers
US5830655A (en) 1995-05-22 1998-11-03 Sri International Oligonucleotide sizing using cleavable primers
EP0886681A1 (de) 1996-03-04 1998-12-30 Genetrace Systems, Inc. Verfahren zur suche von nukleinsäuren mit massenspektroskopie
US5965363A (en) 1996-09-19 1999-10-12 Genetrace Systems Inc. Methods of preparing nucleic acids for mass spectrometric analysis
US7285422B1 (en) 1997-01-23 2007-10-23 Sequenom, Inc. Systems and methods for preparing and analyzing low volume analyte array elements
CA2268740C (en) 1996-11-06 2010-07-20 Sequenom, Inc. High density immobilization of nucleic acids
EP0954612A2 (de) 1996-11-06 1999-11-10 Sequenom, Inc. Dna-diagnostik mittels massenspektrometrie
JP2001524808A (ja) 1996-12-10 2001-12-04 ジーントレイス・システムズ・インコーポレイテッド 放出可能な不揮発性の質量標識分子
DE60041072D1 (de) 1999-07-26 2009-01-22 Clinical Micro Sensors Inc Em nachweis
US6107061A (en) * 1999-09-18 2000-08-22 The Perkin-Elmer Corporation Modified primer extension reactions for polynucleotide sequence detection
US6518024B2 (en) * 1999-12-13 2003-02-11 Motorola, Inc. Electrochemical detection of single base extension
US6762018B1 (en) 1999-12-23 2004-07-13 Tetragen Sa Analysis of nucleotide polymorphisms at a site
US6824669B1 (en) 2000-02-17 2004-11-30 Motorola, Inc. Protein and peptide sensors using electrical detection methods
US7435541B2 (en) 2000-05-23 2008-10-14 Sequenom, Inc. Restriction enzyme genotyping
CA2409774A1 (en) * 2000-05-23 2001-11-29 Variagenics, Inc. Methods for genetic analysis of dna to detect sequence variances
WO2001096607A2 (en) 2000-06-13 2001-12-20 The Trustees Of Boston University Use of nucleotide analogs in the analysis of oligonucleotide mixtures and in highly multiplexed nucleic acid sequencing
EP1332000B1 (de) 2000-10-30 2012-06-20 Sequenom, Inc. Verfahren zur aufbringung von submikroliter fluid-volumina auf ein substrat
US7226739B2 (en) 2001-03-02 2007-06-05 Isis Pharmaceuticals, Inc Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations
US7666588B2 (en) 2001-03-02 2010-02-23 Ibis Biosciences, Inc. Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
US20040121335A1 (en) 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents associated with host versus graft and graft versus host rejections
US20030027135A1 (en) 2001-03-02 2003-02-06 Ecker David J. Method for rapid detection and identification of bioagents
WO2004060278A2 (en) 2002-12-06 2004-07-22 Isis Pharmaceuticals, Inc. Methods for rapid identification of pathogens in humans and animals
ES2180416B1 (es) * 2001-03-12 2004-06-01 BIOTOOLS BIOTECHNOLOGICAL & MEDICAL LABORATORIES, S.A. Procedimiento para la preparacion de mezclas de reaccion estabilizadas, total o parcialmente desecadas, que comprenden, al menos, una enzima, mezclas de reaccion y kits que las contienen.
US20030143556A1 (en) * 2001-04-03 2003-07-31 Gary Blackburn Nucleic acid reactions using labels with different redox potentials
US8073627B2 (en) 2001-06-26 2011-12-06 Ibis Biosciences, Inc. System for indentification of pathogens
US7217510B2 (en) 2001-06-26 2007-05-15 Isis Pharmaceuticals, Inc. Methods for providing bacterial bioagent characterizing information
US8304184B2 (en) 2002-07-30 2012-11-06 Baback Gharizadeh Genotyping using multiple variant-specific primer pools
US7365039B2 (en) 2003-03-21 2008-04-29 Dow Global Technologies Inc. Morphology controlled olefin polymerization process
US20040209259A1 (en) * 2003-04-16 2004-10-21 Quest Diagnostics Investments Incorporated Methods of determining genotypes in duplicated genes and genomic regions
US8046171B2 (en) 2003-04-18 2011-10-25 Ibis Biosciences, Inc. Methods and apparatus for genetic evaluation
US8057993B2 (en) 2003-04-26 2011-11-15 Ibis Biosciences, Inc. Methods for identification of coronaviruses
US6953764B2 (en) 2003-05-02 2005-10-11 Dow Global Technologies Inc. High activity olefin polymerization catalyst and process
US8158354B2 (en) 2003-05-13 2012-04-17 Ibis Biosciences, Inc. Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US7964343B2 (en) 2003-05-13 2011-06-21 Ibis Biosciences, Inc. Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US8097416B2 (en) 2003-09-11 2012-01-17 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US8546082B2 (en) 2003-09-11 2013-10-01 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US7956175B2 (en) 2003-09-11 2011-06-07 Ibis Biosciences, Inc. Compositions for use in identification of bacteria
US8163895B2 (en) 2003-12-05 2012-04-24 Ibis Biosciences, Inc. Compositions for use in identification of orthopoxviruses
US7666592B2 (en) 2004-02-18 2010-02-23 Ibis Biosciences, Inc. Methods for concurrent identification and quantification of an unknown bioagent
US8119336B2 (en) 2004-03-03 2012-02-21 Ibis Biosciences, Inc. Compositions for use in identification of alphaviruses
EP2458619B1 (de) 2004-05-24 2017-08-02 Ibis Biosciences, Inc. Massenspektrometrie mit selektivem Ionfilter durch digitale Schwelle
US20050266411A1 (en) 2004-05-25 2005-12-01 Hofstadler Steven A Methods for rapid forensic analysis of mitochondrial DNA
US7811753B2 (en) 2004-07-14 2010-10-12 Ibis Biosciences, Inc. Methods for repairing degraded DNA
US8084207B2 (en) 2005-03-03 2011-12-27 Ibis Bioscience, Inc. Compositions for use in identification of papillomavirus
CA2600184A1 (en) 2005-03-03 2006-09-08 Isis Pharmaceuticals, Inc. Compositions for use in identification of adventitious viruses
WO2007014045A2 (en) 2005-07-21 2007-02-01 Isis Pharmaceuticals, Inc. Methods for rapid identification and quantitation of nucleic acid variants
EP1803747A1 (de) 2005-12-30 2007-07-04 Borealis Technology Oy Oberflächemodifizierte Polymerisationskatalysatoren zur Herstellung von Polyolefinfilmen mit niedrigem Gelgehalt
CA2653103A1 (en) 2006-05-05 2007-11-15 Dow Global Technologies Inc. Hafnium complexes of carbazolyl substituted imidazole ligands
JP2010510476A (ja) 2006-07-19 2010-04-02 バイオナノマトリックス、インク. ナノノズル装置アレイ:その作製および高分子分析における利用
JP5420412B2 (ja) 2006-09-14 2014-02-19 アイビス バイオサイエンシズ インコーポレイティッド 病原体の同定のための標的全ゲノム増幅方法
WO2008104002A2 (en) 2007-02-23 2008-08-28 Ibis Biosciences, Inc. Methods for rapid forensic dna analysis
EP2610008A1 (de) 2007-03-28 2013-07-03 BioNano Genomics, Inc. Verfahren zur makromolekularen Analyse mittels Nanokanalanordnungen
WO2008151023A2 (en) 2007-06-01 2008-12-11 Ibis Biosciences, Inc. Methods and compositions for multiple displacement amplification of nucleic acids
US20090180931A1 (en) 2007-09-17 2009-07-16 Sequenom, Inc. Integrated robotic sample transfer device
TW200932762A (en) 2007-10-22 2009-08-01 Univation Tech Llc Polyethylene compositions having improved properties
TW200936619A (en) 2007-11-15 2009-09-01 Univation Tech Llc Polymerization catalysts, methods of making, methods of using, and polyolefin products made therefrom
CA3062190C (en) 2008-06-30 2023-03-28 Bionano Genomics, Inc. Methods and devices for single-molecule whole genome analysis
WO2010033625A1 (en) 2008-09-16 2010-03-25 Ibis Biosciences, Inc. Microplate handling systems and related computer program products and methods
WO2010033627A2 (en) 2008-09-16 2010-03-25 Ibis Biosciences, Inc. Sample processing units, systems, and related methods
US8550694B2 (en) 2008-09-16 2013-10-08 Ibis Biosciences, Inc. Mixing cartridges, mixing stations, and related kits, systems, and methods
CN104372080B (zh) * 2008-11-18 2018-03-30 博纳基因技术有限公司 多核苷酸作图和测序
WO2010080871A1 (en) 2009-01-08 2010-07-15 Univation Technologies, Llc Additive for gas phase polymerization processes
EP2376540B1 (de) 2009-01-08 2013-04-03 Univation Technologies, LLC Zusatzstoff für polyolefinpolymerisierungsverfahren
EP2396803A4 (de) 2009-02-12 2016-10-26 Ibis Biosciences Inc Ionisationssondenanordnungen
US8950604B2 (en) 2009-07-17 2015-02-10 Ibis Biosciences, Inc. Lift and mount apparatus
US9194877B2 (en) 2009-07-17 2015-11-24 Ibis Biosciences, Inc. Systems for bioagent indentification
BRPI1015361A2 (pt) 2009-07-23 2018-02-20 Univation Tech Llc sistema de reação de polimerização
EP2957641B1 (de) 2009-10-15 2017-05-17 Ibis Biosciences, Inc. Multiple-displacement-amplifikation
US8598283B2 (en) 2010-02-18 2013-12-03 Univation Technologies, Llc Methods for operating a polymerization reactor
ES2693720T3 (es) 2010-02-22 2018-12-13 Univation Technologies, Llc Sistemas catalíticos y métodos para usar los mismos para producir productos poliolefínicos
MY157091A (en) 2010-04-13 2016-04-29 Univation Tech Llc Polymer blends and films made therefrom
WO2012009215A1 (en) 2010-07-16 2012-01-19 Univation Technologies, Llc Systems and methods for measuring static charge on particulates
RU2564301C2 (ru) 2010-07-16 2015-09-27 Юнивейшн Текнолоджиз, Ллк Системы и способы измерения накопления частиц на поверхностях реактора
WO2012015898A1 (en) 2010-07-28 2012-02-02 Univation Technologies, Llc Systems and methods for measuring velocity of a particle/fluid mixture
EP2651982B1 (de) 2010-12-17 2018-04-11 Univation Technologies, LLC Systeme und verfahren zur rückgewinnung von kohlenwasserstoffen aus einem polyolefinspülgasprodukt
EP2655432B1 (de) 2010-12-22 2017-08-02 Univation Technologies, LLC Zusatzstoff für polyolefinpolymerisierungsverfahren
JP6040227B2 (ja) 2011-05-19 2016-12-07 アジーナ バイオサイエンス, インコーポレイテッド マルチプレックス核酸同定のための製品およびプロセス
WO2013028283A1 (en) 2011-08-19 2013-02-28 Univation Technologies, Llc Catalyst systems and methods for using same to produce polyolefin products
CN103930452B (zh) 2011-11-08 2016-08-31 尤尼威蒂恩技术有限责任公司 采用催化剂体系生产聚烯烃的方法
WO2013133956A2 (en) 2012-03-05 2013-09-12 Univation Technologies, Llc Methods for making catalyst compositions and polymer products produced therefrom
CA2800056A1 (en) 2012-12-24 2014-06-24 Nova Chemicals Corporation Polyethylene blend compositions
ES2918582T3 (es) 2012-12-28 2022-07-19 Univation Tech Llc Catalizador soportado con fluidez mejorada
WO2014123598A1 (en) 2013-02-07 2014-08-14 Univation Technologies, Llc Preparation of polyolefin
CN105143281B (zh) 2013-03-15 2018-06-01 尤尼威蒂恩技术有限责任公司 用于烯烃聚合催化剂的三齿氮类配体
US9718900B2 (en) 2013-03-15 2017-08-01 Univation Technologies, Llc Ligands for catalysts
EP3004032B1 (de) 2013-06-05 2017-12-13 Univation Technologies, LLC Schutz von phenolgruppen
US10208139B2 (en) 2014-08-19 2019-02-19 Univation Technologies, Llc Fluorinated catalyst supports and catalyst systems
SG11201701265UA (en) 2014-08-19 2017-03-30 Univation Tech Llc Fluorinated catalyst supports and catalyst systems
WO2016028277A1 (en) 2014-08-19 2016-02-25 Univation Technologies, Llc Fluorinated catalyst supports and catalyst systems
WO2016118566A1 (en) 2015-01-21 2016-07-28 Univation Technologies, Llc Methods for gel reduction in polyolefins
CA2974392C (en) 2015-01-21 2023-10-17 Univation Technologies, Llc Methods for controlling polymer chain scission
EP3286328B1 (de) 2015-04-24 2020-10-21 Agena Bioscience, Inc. Multiplex verfahrens für detektion und quantifizierung leichten varianten
EP3286327B1 (de) 2015-04-24 2021-11-10 Agena Bioscience, Inc. Gemultiplexte verfahren zur identifizierung und quantifizierung von minder vorhandenen allelen und polymorphismen
EP3091083B1 (de) * 2015-05-07 2017-11-08 Latvian Biomedical Research and Study Centre Kit zum nachweis von mutation oder von polymorphismus in mitochondrialer dna
US10377841B2 (en) 2015-05-08 2019-08-13 Exxonmobil Chemical Patents Inc. Polymerization process
WO2018063767A1 (en) 2016-09-27 2018-04-05 Exxonmobil Chemical Patents Inc. Polymerization process
CN109983039B (zh) 2016-09-27 2022-02-18 尤尼威蒂恩技术有限责任公司 用于聚乙烯生产中长链支化控制的方法
WO2018063764A1 (en) 2016-09-27 2018-04-05 Exxonmobil Chemical Patents Inc. Polymerization process
WO2018063765A1 (en) 2016-09-27 2018-04-05 Exxonmobil Chemical Patents Inc. Polymerization process
WO2018118155A1 (en) 2016-12-20 2018-06-28 Exxonmobil Chemical Patents Inc. Polymerization process
SG11201907244SA (en) 2017-02-07 2019-09-27 Exxonmobil Chemical Patents Inc Processes for reducing the loss of catalyst activity of a ziegler-natta catalyst
WO2018191000A1 (en) 2017-04-10 2018-10-18 Exxonmobil Chemicl Patents Inc. Methods for making polyolefin polymer compositions
JP6868714B2 (ja) 2017-05-10 2021-05-12 ユニベーション・テクノロジーズ・エルエルシー 触媒系およびその使用のためのプロセス
AU2018265274B2 (en) * 2017-05-11 2021-10-07 Gen-Probe Incorporated Compositions and methods for isolating target nucleic acids
US11591417B2 (en) 2017-12-13 2023-02-28 Exxonmobil Chemical Patents Inc. Deactivation methods for active components from gas phase polyolefin polymerization processes
WO2019173030A1 (en) 2018-03-08 2019-09-12 Exxonmobil Chemical Patents Inc. Methods of preparing and monitoring a seed bed for polymerization reactor startup
GB201804642D0 (en) 2018-03-22 2018-05-09 Inivata Ltd Methods of labelling nucleic acids
US11459408B2 (en) 2018-05-02 2022-10-04 Exxonmobil Chemical Patents Inc. Methods for scale-up from a pilot plant to a larger production facility
US11447587B2 (en) 2018-05-02 2022-09-20 Exxonmobil Chemical Patents Inc. Methods for scale-up from a pilot plant to a larger production facility
WO2022020025A1 (en) 2020-07-22 2022-01-27 Exxonmobil Chemical Patents Inc. Polyolefin compositions and articles thereof
US20230406973A1 (en) 2020-12-08 2023-12-21 Exxonmobil Chemical Patents Inc. High density polyethylene compositions with long-chain branching

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6004744A (en) * 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
JP2775346B2 (ja) * 1992-04-03 1998-07-16 アプライド バイオシステムズ,インコーポレイテッド プローブ構成物および方法
JPH09507121A (ja) * 1993-10-26 1997-07-22 アフィマックス テクノロジーズ ナームロゼ ベノートスハップ 生物学的チップ上の核酸プローブアレー

Also Published As

Publication number Publication date
US5925520A (en) 1999-07-20
AU3263095A (en) 1996-03-14
EP0777747B1 (de) 2001-12-05
DK0777747T3 (da) 2002-04-08
ES2169143T3 (es) 2002-07-01
DE69524425T2 (de) 2002-08-01
DE69524425D1 (de) 2002-01-17
PT777747E (pt) 2002-05-31
WO1996006187A1 (en) 1996-02-29
EP0777747A1 (de) 1997-06-11
GB9417211D0 (en) 1994-10-12

Similar Documents

Publication Publication Date Title
DE69524425D1 (de) Nukleotid-sequenzierungsmethode
PL278176A1 (en) Method of detecting sequences of nucleotides and sets for carrying out diagnostic tests
ATE250142T1 (de) Methode zur sequenzierung von polynukleotiden
ES2093633T3 (es) Amplificacion de acidos nucleicos utilizando un unico cebador.
ATE250671T1 (de) Verfahren mit einer hohen umsatzrate für das auffinden von sequenzen oder genetischen veränderungen in nukleinsäuren
SE8500733D0 (sv) Nukleinsyrareagens, sett for deras framstellning och deras anvendning
SE9400522D0 (sv) Method and reagent for detecting specific nucleotide sequences
DE69430909D1 (de) Dns-sequenzbestimmung durch massenspektrometrie auf dem weg des abbaus mit exonuklease
ATE321883T1 (de) DE NOVO ODER ßUNIVERSALERß SEQUENZIERUNGS-ARRAY
DE60013591D1 (de) Screening nach modulatoren der funktion von immunstimulatorischer dna
BR0214683A (pt) Molécula de nucleotìdeo ou de nucleosìdeo, métodos de rotular uma molécula de ácido nucléico e para determinar a sequência de um polinucleotìdeo alvo de filamento único, e, kit
ES8707343A1 (es) Un metodo para aislar una secuencia de acido nucleico objetivo seleccionada
DK153289A (da) Selektiv forstaerkning af maal-polynucleotidsekvenser
DE59103063D1 (de) Verfahren zur bestimmung von polymerase-aktivität.
ATE290606T1 (de) Bestimmung der länge von repetitiven nukleinsäuresequenzen durch eine diskontinuierliche verlängerung von startermolekülen
ATE24971T1 (de) Iodthyronin-immunoassays, bei welchen hms als tbp-blocker verwendet wird.
DE69941690D1 (de) Methoden, testsätze und kompositionen zur detektion und quantifizierung von zielsequenzen
DE59801996D1 (de) Verfahren zur eingruppierung von sequenzen in familien
ATE311477T1 (de) Hohe dichte markierung von dns mit modifizierte oder chromophore tragende nukleotide und benutzte dns polymerasen
EP1795597A3 (de) in neuroblastom isolierte nukleinsäuren
KR960037841A (ko) 결핵 진단용 탐침

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 0777747

Country of ref document: EP