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ATE202768T1 - D-mannit und seine herstellung - Google Patents

D-mannit und seine herstellung

Info

Publication number
ATE202768T1
ATE202768T1 AT97916654T AT97916654T ATE202768T1 AT E202768 T1 ATE202768 T1 AT E202768T1 AT 97916654 T AT97916654 T AT 97916654T AT 97916654 T AT97916654 T AT 97916654T AT E202768 T1 ATE202768 T1 AT E202768T1
Authority
AT
Austria
Prior art keywords
mannite
production
mannitol
excipient
useful
Prior art date
Application number
AT97916654T
Other languages
English (en)
Inventor
Tomohiro Yoshinari
Fritz Schueckler
Norbert Poellinger
Shinji Maegata
Original Assignee
Takeda Chemical Industries Ltd
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=14109240&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE202768(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Chemical Industries Ltd, Bayer Ag filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE202768T1 publication Critical patent/ATE202768T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C31/18—Polyhydroxylic acyclic alcohols
    • C07C31/26—Hexahydroxylic alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
    • C07C29/76—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Steroid Compounds (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
AT97916654T 1996-04-16 1997-04-14 D-mannit und seine herstellung ATE202768T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP9440196 1996-04-16
PCT/JP1997/001286 WO1997038960A1 (en) 1996-04-16 1997-04-14 D-mannitol and its preparation

Publications (1)

Publication Number Publication Date
ATE202768T1 true ATE202768T1 (de) 2001-07-15

Family

ID=14109240

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97916654T ATE202768T1 (de) 1996-04-16 1997-04-14 D-mannit und seine herstellung

Country Status (27)

Country Link
US (1) US6503918B2 (de)
EP (1) EP0902777B2 (de)
KR (1) KR20000005486A (de)
CN (1) CN1221398A (de)
AT (1) ATE202768T1 (de)
AU (1) AU718658B2 (de)
BG (1) BG63460B1 (de)
BR (1) BR9708672A (de)
CA (1) CA2251092A1 (de)
CU (1) CU22776A3 (de)
CZ (1) CZ333698A3 (de)
DE (1) DE69705516T3 (de)
DK (1) DK0902777T4 (de)
EA (1) EA000968B1 (de)
ES (1) ES2158540T5 (de)
GR (1) GR3036760T3 (de)
HU (1) HUP9902165A3 (de)
ID (1) ID16566A (de)
IL (1) IL126580A (de)
NO (2) NO311349B1 (de)
NZ (1) NZ332313A (de)
PL (1) PL329614A1 (de)
PT (1) PT902777E (de)
SK (1) SK282768B6 (de)
TR (1) TR199802079T2 (de)
TW (1) TW515787B (de)
WO (1) WO1997038960A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10008506A1 (de) * 2000-02-24 2001-09-13 Bayer Ag Verfahren zur Herstellung von pharmazeutischen Darreichungsformen
FR2807034B1 (fr) † 2000-03-29 2002-06-14 Roquette Freres Mannitol pulverulent et son procede de fabrication
JPWO2002024167A1 (ja) * 2000-09-19 2004-01-29 第一製薬株式会社 医薬組成物
US6979462B1 (en) * 2000-10-03 2005-12-27 Mutual Pharmaceutical Co., Inc. Stabilization of solid drug formulations
US6855333B1 (en) 2000-10-03 2005-02-15 Mutual Pharmaceutical Co., Inc. Stabilization of solid thyroid drug formulations
DE10161402A1 (de) * 2001-12-13 2003-06-18 Merck Patent Gmbh Verfahren zur Herstellung von direkt tablettierbarem beta-Mannit
EP1575487B1 (de) * 2002-05-14 2019-08-14 DuPont Nutrition USA, Inc. Coattrittierte mikrokristalline zellulose hydrokolloid-zusammensetzungen und verfahren zur herstellung
US8163797B2 (en) * 2003-12-31 2012-04-24 Actavis Elizabeth Llc Method of treating with stable pravastatin formulation
US7879382B2 (en) * 2005-09-30 2011-02-01 Fmc Corporation Stabilizers and compositions and products comprising same
JP5053865B2 (ja) 2005-12-28 2012-10-24 武田薬品工業株式会社 口腔内崩壊性固形製剤の製造法
SG183583A1 (en) 2006-02-20 2012-09-27 Chugai Pharmaceutical Co Ltd Pharmaceutical composition comprising oseltamivir phosphate
EP2076250B1 (de) * 2006-10-27 2011-01-05 FMC Corporation Gemeinsam aufbereitete mikrokristalline cellulose und zuckeralkohol als hilfsstoff für tablettenformulierungen
CA2680536A1 (en) 2007-03-13 2008-10-09 Dainippon Sumitomo Pharma Co., Ltd. Oral disintegrating tablet
CA2687813C (en) * 2007-05-22 2015-07-07 Ssci, Inc. Preparation of mannitol modification iii
DE102007052070A1 (de) 2007-10-30 2009-05-07 Tiefenbacher Pharmachemikalien Alfred E. Tiefenbacher Gmbh & Co. Kg Candesartancilexetil
CN103429229A (zh) 2010-12-17 2013-12-04 默克专利股份有限公司 可直接压片的δ-甘露糖醇的制备方法
US9055757B2 (en) 2011-10-05 2015-06-16 Fmc Corporation Stabilizer composition of co-attrited microcrystalline cellulose and carboxymethylcellulose, method for making, and uses
WO2013052114A1 (en) 2011-10-05 2013-04-11 Fmc Corporation Stabilizer composition of microcrystalline cellulose and carboxymethylcellulose, method for making, and uses
PL2787837T3 (pl) 2011-12-09 2017-09-29 Fmc Corporation Współścierana kompozycja stabilizatora
KR102501024B1 (ko) * 2014-07-21 2023-02-20 로께뜨프레르 직접 압축에 의한 타정을 위한 당 조성물
IT201900002857A1 (it) 2019-02-27 2020-08-27 Ntc S R L Procedimento di riempimento di contenitori con una polvere
MX2022011215A (es) * 2020-03-31 2022-10-07 Eisai R&D Man Co Ltd Comprimido, medicamento, metodos para producirlos y kit.
CN113116843A (zh) * 2021-05-11 2021-07-16 福建海西新药创制有限公司 一种含有缬沙坦的药物组合物及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3145146A (en) 1961-10-31 1964-08-18 Warner Lambert Pharmaceutical Modified mannitol for pharmaceutical tablets
DE3245170A1 (de) 1982-12-07 1984-06-07 Merck Patent Gmbh, 6100 Darmstadt Verbesserter sorbit, verfahren zur herstellung und verwendung
FR2571046B1 (fr) 1984-10-03 1987-10-16 Roquette Freres Procede de preparation de mannitol granulaire directement compressible
FR2571045B1 (fr) 1984-10-03 1987-12-11 Roquette Freres Mannitol granulaire directement compressible et son procede de fabrication
JPH0653658B2 (ja) 1984-12-17 1994-07-20 中外製薬株式会社 安定な錠剤の製造法
NO177005C (no) 1988-01-20 1995-07-05 Bayer Ag Analogifremgangsmåte for fremstilling av substituerte pyridiner, samt mellomprodukter til bruk ved fremstillingen
DE69022861T2 (de) 1989-01-24 1996-04-04 Spi Polyols Inc Kryoschützende kristalline Sorbitolkügelchen.
ATE99545T1 (de) 1989-03-29 1994-01-15 Takeda Chemical Industries Ltd Zusammensetzung mit einer verbindung der vitamin b-gruppe und ihre herstellung.
US5177080A (en) 1990-12-14 1993-01-05 Bayer Aktiengesellschaft Substituted pyridyl-dihydroxy-heptenoic acid and its salts
HU9203780D0 (en) * 1991-12-12 1993-03-29 Sandoz Ag Stabilized pharmaceutical products of hmg-coa reductase inhibitor and method for producing them
FR2710637B1 (fr) 1993-09-28 1995-12-08 Roquette Freres Mannitol pulvérulent de friabilité modérée et son procédé de préparation.
AUPM411494A0 (en) 1994-02-25 1994-03-24 Central Sydney Area Health Service Method and device for the provocation of upper or lower airway narrowing and/or the induction of sputum
US6235947B1 (en) * 1997-04-14 2001-05-22 Takeda Chemical Industries, Ltd. D-mannitol and its preparation

Also Published As

Publication number Publication date
DE69705516D1 (de) 2001-08-09
NO20012249D0 (no) 2001-05-07
SK143298A3 (en) 1999-04-13
ES2158540T3 (es) 2001-09-01
NO311349B1 (no) 2001-11-19
NO20012249L (no) 1998-12-16
US20020107420A1 (en) 2002-08-08
EP0902777B2 (de) 2004-06-16
DK0902777T3 (da) 2001-09-24
EA199800888A1 (ru) 1999-04-29
ID16566A (id) 1997-10-16
CZ333698A3 (cs) 1999-01-13
PT902777E (pt) 2001-11-30
AU718658B2 (en) 2000-04-20
CN1221398A (zh) 1999-06-30
ES2158540T5 (es) 2004-11-16
BG63460B1 (bg) 2002-02-28
US6503918B2 (en) 2003-01-07
PL329614A1 (en) 1999-03-29
TW515787B (en) 2003-01-01
NZ332313A (en) 2000-02-28
AU2522297A (en) 1997-11-07
BG102818A (en) 1999-05-31
EP0902777A1 (de) 1999-03-24
TR199802079T2 (xx) 1999-02-22
DK0902777T4 (da) 2004-10-11
DE69705516T3 (de) 2004-09-30
IL126580A0 (en) 1999-08-17
IL126580A (en) 2001-08-08
GR3036760T3 (en) 2001-12-31
NO984803L (no) 1998-12-16
EP0902777B1 (de) 2001-07-04
BR9708672A (pt) 1999-08-03
HUP9902165A3 (en) 2001-01-29
HUP9902165A2 (hu) 1999-11-29
NO984803D0 (no) 1998-10-15
SK282768B6 (sk) 2002-12-03
WO1997038960A1 (en) 1997-10-23
KR20000005486A (ko) 2000-01-25
CU22776A3 (es) 2002-07-24
CA2251092A1 (en) 1997-10-23
DE69705516T2 (de) 2002-04-25
EA000968B1 (ru) 2000-08-28

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Legal Events

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UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee
UEP Publication of translation of european patent specification

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