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ATE285754T1 - PHARMACEUTICAL COMPOSITION CONTAINING LYOPHILIZED LYPOSOMES INCLUDING AN INSOLUBLE ACTIVE INGREDIENT, METHOD FOR THE PRODUCTION THEREOF - Google Patents

PHARMACEUTICAL COMPOSITION CONTAINING LYOPHILIZED LYPOSOMES INCLUDING AN INSOLUBLE ACTIVE INGREDIENT, METHOD FOR THE PRODUCTION THEREOF

Info

Publication number
ATE285754T1
ATE285754T1 AT98910659T AT98910659T ATE285754T1 AT E285754 T1 ATE285754 T1 AT E285754T1 AT 98910659 T AT98910659 T AT 98910659T AT 98910659 T AT98910659 T AT 98910659T AT E285754 T1 ATE285754 T1 AT E285754T1
Authority
AT
Austria
Prior art keywords
lyposomes
production
pharmaceutical composition
active ingredient
composition containing
Prior art date
Application number
AT98910659T
Other languages
German (de)
Inventor
Giovanni Cavallo
Leonardo Marchitto
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Application granted granted Critical
Publication of ATE285754T1 publication Critical patent/ATE285754T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT98910659T 1997-02-20 1998-02-12 PHARMACEUTICAL COMPOSITION CONTAINING LYOPHILIZED LYPOSOMES INCLUDING AN INSOLUBLE ACTIVE INGREDIENT, METHOD FOR THE PRODUCTION THEREOF ATE285754T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT97MI000362A IT1289938B1 (en) 1997-02-20 1997-02-20 PHARMACEUTICAL PREPARATION INCLUDING LYOPHYLIZED LIPOSOMES IN WHICH A HIGHLY WATER-INSOLUBLE ACTIVE SUBSTANCE IS ENCAPSULATED AND
PCT/EP1998/000817 WO1998036736A1 (en) 1997-02-20 1998-02-12 Pharmaceutical preparation comprising lyophilized liposomes encapsulating an active principle which is highly insoluble in water, and the process for preparing the said preparation

Publications (1)

Publication Number Publication Date
ATE285754T1 true ATE285754T1 (en) 2005-01-15

Family

ID=11376097

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98910659T ATE285754T1 (en) 1997-02-20 1998-02-12 PHARMACEUTICAL COMPOSITION CONTAINING LYOPHILIZED LYPOSOMES INCLUDING AN INSOLUBLE ACTIVE INGREDIENT, METHOD FOR THE PRODUCTION THEREOF

Country Status (25)

Country Link
US (1) US6319517B1 (en)
EP (1) EP0981332B1 (en)
JP (1) JP4290767B2 (en)
KR (1) KR100496802B1 (en)
CN (1) CN1089581C (en)
AR (1) AR011681A1 (en)
AT (1) ATE285754T1 (en)
AU (1) AU744115B2 (en)
BG (1) BG64580B1 (en)
CA (1) CA2288958C (en)
CZ (1) CZ295998B6 (en)
DE (1) DE69828394T2 (en)
EA (1) EA001637B1 (en)
ES (1) ES2235320T3 (en)
GE (1) GEP20022734B (en)
HU (1) HU225593B1 (en)
IL (1) IL131327A (en)
IT (1) IT1289938B1 (en)
PL (1) PL190628B1 (en)
PT (1) PT981332E (en)
SK (1) SK282931B6 (en)
TR (1) TR199902025T2 (en)
UA (1) UA70296A (en)
WO (1) WO1998036736A1 (en)
ZA (1) ZA981352B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU762944B2 (en) 1999-06-23 2003-07-10 Cornell Research Foundation Inc. Dehydration/rehydration of marked liposomes on a test device
US6576460B1 (en) 1999-10-28 2003-06-10 Cornell Research Foundation, Inc. Filtration-detection device and method of use
EP1610778A4 (en) * 2003-01-17 2006-05-31 Threshold Pharmaceuticals Inc TREATMENT OF BENIGN PROSTATIC HYPERTROPHY
MX2007012762A (en) 2005-04-12 2008-01-14 Elan Pharma Int Ltd Nanoparticulate and controlled release compositions comprising cyclosporine.
WO2008036979A2 (en) * 2006-09-22 2008-03-27 Guilford F Timothy Topical application of melatonin directly or in liposomes for the amelioration of itching and histamine and non-histamine related inflammatory skin changes
CN101049504B (en) * 2007-04-05 2010-05-19 广州立恩生物科技有限公司 Carrier of liposome medication, and preparation method
US9446147B2 (en) 2011-02-24 2016-09-20 The Ohio State University Membrane stabilizing compositions and methods
CA2852777C (en) 2011-10-21 2020-10-27 Celator Pharmaceuticals Inc. Lyophilized liposomes
US8999292B2 (en) 2012-05-01 2015-04-07 Translatum Medicus Inc. Methods for treating and diagnosing blinding eye diseases
WO2014035206A2 (en) * 2012-08-31 2014-03-06 중앙대학교 산학협력단 Method for preparing microspheres for emboli, and method for preparing microspheres to which drug-containing carrier is bound
US10722465B1 (en) 2017-12-08 2020-07-28 Quicksilber Scientific, Inc. Transparent colloidal vitamin supplement
US11344497B1 (en) 2017-12-08 2022-05-31 Quicksilver Scientific, Inc. Mitochondrial performance enhancement nanoemulsion
KR102649069B1 (en) 2018-05-31 2024-03-19 주식회사 엑소코바이오 Composition for improving face redness comprising an exosome derived from stem cell as an active ingredient
EP3813862A1 (en) * 2018-06-27 2021-05-05 Breath Therapeutics GmbH Inhalable compositions comprising macrocyclic immunosuppressants
EA202092893A1 (en) 2018-06-27 2021-04-19 Брес Терапьютикс Гмбх PHARMACEUTICAL COMPOSITIONS IN LYOPHILIZED FORM
WO2020027466A1 (en) * 2018-07-28 2020-02-06 주식회사 엑소코바이오 Method for lyophilizing exosome
KR102163806B1 (en) 2018-07-30 2020-10-07 주식회사 엑소코바이오 Composition for reducing sebum release comprising an exosome derived from stem cell as an active ingredient
EA202092892A1 (en) 2018-12-04 2021-05-27 Брес Терапьютикс Гмбх INHALATION COMPOSITIONS CONTAINING MACROCYCLIC IMMUNOSUPPRESSANTS
US11291702B1 (en) 2019-04-15 2022-04-05 Quicksilver Scientific, Inc. Liver activation nanoemulsion, solid binding composition, and toxin excretion enhancement method
EP3990433A4 (en) 2019-06-25 2023-07-26 Translatum Medicus Inc. PROCESS FOR THE PREPARATION OF 2-((1-BENZYL-1H-INDAZOLE-3-YL)METHOXY)-2-METHYLPROPANIC ACID AND ITS DERIVATIVES
CN111358955B (en) * 2020-04-01 2023-05-02 重庆理工大学 Inflammation targeted bindarit nanoparticle for treating lipid metabolism diseases, preparation method and application thereof
JP7508359B2 (en) * 2020-12-11 2024-07-01 株式会社東芝 Method for producing lipid particles

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1173360A (en) * 1979-06-22 1984-08-28 Jurg Schrank Pharmaceutical preparations
FR2542749B1 (en) * 1983-03-18 1985-07-12 Beghin Say Sa ALLIFIED ALLYLOLIGOSACCHARIDE-ACRYLIC COPOLYMER, PROCESS FOR PREPARING THE COPOLYMER AND APPLICATION AS SUPER ABSORBENT
US4857319A (en) * 1985-01-11 1989-08-15 The Regents Of The University Of California Method for preserving liposomes
US4963362A (en) * 1987-08-07 1990-10-16 Regents Of The University Of Minnesota Freeze-dried liposome mixture containing cyclosporin
US5683714A (en) * 1991-04-19 1997-11-04 Nexstar Pharmaceuticals, Inc. Liposomal cyclosporin pharmaceutical formulation
US5817336A (en) * 1993-04-02 1998-10-06 Orion-Yhtyma Oy Composition containing selegiline
GB9320668D0 (en) * 1993-10-07 1993-11-24 Secr Defence Liposomes containing particulare materials
AU683957B2 (en) * 1993-11-05 1997-11-27 Amgen, Inc. Liposome preparation and material encapsulation method

Also Published As

Publication number Publication date
IL131327A (en) 2004-07-25
HK1026148A1 (en) 2000-12-08
HUP0001464A2 (en) 2000-10-28
DE69828394D1 (en) 2005-02-03
CZ292599A3 (en) 2000-01-12
SK111099A3 (en) 2000-05-16
BG103738A (en) 2000-05-31
JP4290767B2 (en) 2009-07-08
SK282931B6 (en) 2003-01-09
US6319517B1 (en) 2001-11-20
GEP20022734B (en) 2002-07-25
CN1089581C (en) 2002-08-28
JP2001519776A (en) 2001-10-23
PL335207A1 (en) 2000-04-10
AU744115B2 (en) 2002-02-14
UA70296C2 (en) 2004-10-15
HU225593B1 (en) 2007-05-02
ES2235320T3 (en) 2005-07-01
PL190628B1 (en) 2005-12-30
ITMI970362A1 (en) 1998-08-20
KR20000075479A (en) 2000-12-15
PT981332E (en) 2005-05-31
IL131327A0 (en) 2001-01-28
HUP0001464A3 (en) 2001-12-28
AR011681A1 (en) 2000-08-30
BG64580B1 (en) 2005-08-31
AU6496998A (en) 1998-09-09
CA2288958A1 (en) 1998-08-27
CZ295998B6 (en) 2005-12-14
KR100496802B1 (en) 2005-06-22
EA001637B1 (en) 2001-06-25
WO1998036736A1 (en) 1998-08-27
TR199902025T2 (en) 1999-11-22
CN1248163A (en) 2000-03-22
UA70296A (en) 2004-10-15
CA2288958C (en) 2007-08-21
EP0981332A1 (en) 2000-03-01
ZA981352B (en) 1998-08-19
EA199900751A1 (en) 2000-10-30
IT1289938B1 (en) 1998-10-19
EP0981332B1 (en) 2004-12-29
DE69828394T2 (en) 2005-12-08

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