ATE279433T1 - Cystein-protease-inhibitoren für die behandlung von allergischenkrankheiten verursacht durch ige - Google Patents
Cystein-protease-inhibitoren für die behandlung von allergischenkrankheiten verursacht durch igeInfo
- Publication number
- ATE279433T1 ATE279433T1 AT96924976T AT96924976T ATE279433T1 AT E279433 T1 ATE279433 T1 AT E279433T1 AT 96924976 T AT96924976 T AT 96924976T AT 96924976 T AT96924976 T AT 96924976T AT E279433 T1 ATE279433 T1 AT E279433T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- allergens
- pct
- treatment
- allergic diseases
- Prior art date
Links
- 238000011282 treatment Methods 0.000 title abstract 3
- 208000010668 atopic eczema Diseases 0.000 title abstract 2
- 230000000172 allergic effect Effects 0.000 title 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 title 1
- 229940042399 direct acting antivirals protease inhibitors Drugs 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 239000000137 peptide hydrolase inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 7
- 239000013566 allergen Substances 0.000 abstract 5
- 208000026935 allergic disease Diseases 0.000 abstract 4
- 208000006673 asthma Diseases 0.000 abstract 2
- 230000007613 environmental effect Effects 0.000 abstract 2
- 238000011065 in-situ storage Methods 0.000 abstract 2
- 230000002779 inactivation Effects 0.000 abstract 2
- 230000001404 mediated effect Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 201000004624 Dermatitis Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 230000037446 allergic sensitization Effects 0.000 abstract 1
- 230000006378 damage Effects 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 230000000366 juvenile effect Effects 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 230000035899 viability Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
- C07K5/06052—Val-amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9514616.3A GB9514616D0 (en) | 1995-07-17 | 1995-07-17 | Cleavage of low affinity receptor for human IgE |
| GBGB9522221.2A GB9522221D0 (en) | 1995-10-31 | 1995-10-31 | Compounds for use in treatment of ige mediated allergic diseases |
| PCT/GB1996/001707 WO1997004004A1 (en) | 1995-07-17 | 1996-07-17 | CYSTEINE PROTEASE INHIBITORS FOR USE IN TREATMENT OF IgE MEDIATED ALLERGIC DISEASES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE279433T1 true ATE279433T1 (de) | 2004-10-15 |
Family
ID=26307419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96924976T ATE279433T1 (de) | 1995-07-17 | 1996-07-17 | Cystein-protease-inhibitoren für die behandlung von allergischenkrankheiten verursacht durch ige |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6034066A (de) |
| EP (1) | EP0839155B1 (de) |
| JP (1) | JPH11509543A (de) |
| AT (1) | ATE279433T1 (de) |
| AU (1) | AU716716B2 (de) |
| CA (1) | CA2227198A1 (de) |
| DE (1) | DE69633623T2 (de) |
| ES (1) | ES2230566T3 (de) |
| WO (1) | WO1997004004A1 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6020331A (en) * | 1995-03-24 | 2000-02-01 | Molecumetics, Ltd. | β-sheet mimetics and use thereof as protease inhibitors |
| US6699869B1 (en) * | 1995-03-24 | 2004-03-02 | Myriad Genetics Inc. | β-sheet mimetics and use thereof as inhibitors of biologically active peptides or proteins |
| KR20000022040A (ko) | 1996-06-20 | 2000-04-25 | 보오드 오브 리젠츠, 더 유니버시티 오브 텍사스 시스템 | 약학적 활성 제제를 제공하기 위한 화합물, 방법 및 그의 용도 |
| GB9726114D0 (en) * | 1997-12-11 | 1998-02-11 | Univ Manchester | Prevention and/or treatment of allergic conditions |
| CA2225325A1 (en) * | 1997-12-19 | 1999-06-19 | The University Of British Columbia | Hemiasterlin analogs |
| US6913749B2 (en) * | 1998-11-02 | 2005-07-05 | Resistentia Pharmaceuticals Ab | Immunogenic polypeptides for inducing anti-self IgE responses |
| US7759133B2 (en) * | 1998-12-22 | 2010-07-20 | Alk-Abello A/S | Method of detecting and/or quantifying a specific IgE antibody in a liquid sample |
| US6649593B1 (en) * | 1999-10-13 | 2003-11-18 | Tularik Inc. | Modulators of SREBP processing |
| US6849260B2 (en) | 2000-08-18 | 2005-02-01 | Amgen Inc. | Methods and compositions for treating IgE-related disease using NNT-1 inhibitors |
| US20070196353A1 (en) * | 2001-05-25 | 2007-08-23 | Hugh Payton | Method for reducing allergenicity in indoor spaces |
| US20020176854A1 (en) * | 2001-05-25 | 2002-11-28 | Payton Hugh W. | Method for reducing allergenicity in indoor spaces |
| AU2003219809A1 (en) * | 2002-02-14 | 2003-09-04 | Myriad Genetics, Inc. | Beta-sheet mimetics and composition and methods relating thereto |
| US20040007251A1 (en) * | 2002-07-10 | 2004-01-15 | Kimberly-Clark Worldwide, Inc. | Cleaners for the control and removal of allergens |
| US7037535B2 (en) * | 2002-11-19 | 2006-05-02 | Kimberly-Clark Worldwide, Inc. | Method and composition for neutralizing house dust mite feces |
| US7211407B2 (en) * | 2003-07-15 | 2007-05-01 | Chan Test, Inc. | High throughput assay systems and methods for identifying agents that alter surface expression of integral membrane proteins |
| WO2006099261A2 (en) * | 2005-03-11 | 2006-09-21 | The University Of North Carolina At Chapel Hill | Potent and specific immunoproteasome inhibitors |
| US20080118524A1 (en) * | 2006-10-20 | 2008-05-22 | Stefan Persson | Anti-IgE Vaccines |
| US20100279997A1 (en) | 2009-05-04 | 2010-11-04 | Lindsay Burns Barbier | Analgesic that binds filamin a |
| US20100279996A1 (en) | 2009-05-04 | 2010-11-04 | Lindsay Burns Barbier | Novel analgesic that binds filamin a |
| GB201001070D0 (en) * | 2010-01-22 | 2010-03-10 | St George's Hospital Medical School | Theraputic compounds and their use |
| GB201011411D0 (en) * | 2010-07-06 | 2010-08-18 | St Georges Hosp Medical School | Therapeutic compounds and their use |
| US9433604B2 (en) | 2013-10-08 | 2016-09-06 | Pain Therapeutics Inc. | Method for inhibiting growth of cancer cells |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH603513A5 (de) * | 1975-02-05 | 1978-08-15 | Sandoz Ag | |
| JPH04273896A (ja) * | 1991-02-27 | 1992-09-30 | Taisho Pharmaceut Co Ltd | トリペプチド誘導体 |
| JPH05213990A (ja) * | 1991-02-27 | 1993-08-24 | Taisho Pharmaceut Co Ltd | トリペプチド誘導体 |
| JPH04273897A (ja) * | 1991-02-27 | 1992-09-30 | Taisho Pharmaceut Co Ltd | トリペプチド誘導体 |
| CA2178620A1 (en) * | 1993-12-08 | 1995-06-15 | Lisa B. Jungherr | Microsphere drug delivery system |
| US5486623A (en) * | 1993-12-08 | 1996-01-23 | Prototek, Inc. | Cysteine protease inhibitors containing heterocyclic leaving groups |
| US5714484A (en) * | 1993-12-08 | 1998-02-03 | Prototek, Inc. | α-(1,3-dicarbonylenol ether) methyl ketones as cysteine protease inhibitors |
-
1996
- 1996-07-17 AU AU65242/96A patent/AU716716B2/en not_active Ceased
- 1996-07-17 CA CA002227198A patent/CA2227198A1/en not_active Abandoned
- 1996-07-17 US US09/000,045 patent/US6034066A/en not_active Expired - Lifetime
- 1996-07-17 JP JP9506421A patent/JPH11509543A/ja active Pending
- 1996-07-17 DE DE69633623T patent/DE69633623T2/de not_active Expired - Lifetime
- 1996-07-17 EP EP96924976A patent/EP0839155B1/de not_active Expired - Lifetime
- 1996-07-17 ES ES96924976T patent/ES2230566T3/es not_active Expired - Lifetime
- 1996-07-17 WO PCT/GB1996/001707 patent/WO1997004004A1/en not_active Ceased
- 1996-07-17 AT AT96924976T patent/ATE279433T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU6524296A (en) | 1997-02-18 |
| EP0839155A1 (de) | 1998-05-06 |
| JPH11509543A (ja) | 1999-08-24 |
| WO1997004004A1 (en) | 1997-02-06 |
| DE69633623D1 (de) | 2004-11-18 |
| AU716716B2 (en) | 2000-03-02 |
| ES2230566T3 (es) | 2005-05-01 |
| DE69633623T2 (de) | 2005-12-01 |
| CA2227198A1 (en) | 1997-02-06 |
| US6034066A (en) | 2000-03-07 |
| EP0839155B1 (de) | 2004-10-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |