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ATE247948T1 - Verfahren zum inhalieren trockener pulver - Google Patents

Verfahren zum inhalieren trockener pulver

Info

Publication number
ATE247948T1
ATE247948T1 AT97921298T AT97921298T ATE247948T1 AT E247948 T1 ATE247948 T1 AT E247948T1 AT 97921298 T AT97921298 T AT 97921298T AT 97921298 T AT97921298 T AT 97921298T AT E247948 T1 ATE247948 T1 AT E247948T1
Authority
AT
Austria
Prior art keywords
dry powder
inhaler
composition
microns
flow rate
Prior art date
Application number
AT97921298T
Other languages
English (en)
Inventor
Robert Schultz
Clyde Witham
Malcolm Hill
Original Assignee
Dura Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21777075&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE247948(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dura Pharma Inc filed Critical Dura Pharma Inc
Application granted granted Critical
Publication of ATE247948T1 publication Critical patent/ATE247948T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Flow Control (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT97921298T 1996-04-29 1997-04-21 Verfahren zum inhalieren trockener pulver ATE247948T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1642896P 1996-04-29 1996-04-29
PCT/US1997/006621 WO1997040819A1 (en) 1996-04-29 1997-04-21 Methods of dry powder inhalation

Publications (1)

Publication Number Publication Date
ATE247948T1 true ATE247948T1 (de) 2003-09-15

Family

ID=21777075

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97921298T ATE247948T1 (de) 1996-04-29 1997-04-21 Verfahren zum inhalieren trockener pulver

Country Status (16)

Country Link
US (1) US6116237A (de)
EP (1) EP0896525B1 (de)
JP (2) JP2000510109A (de)
AT (1) ATE247948T1 (de)
AU (1) AU724503B2 (de)
BR (1) BR9709748A (de)
CA (1) CA2252814A1 (de)
CZ (1) CZ343798A3 (de)
DE (1) DE69724420T2 (de)
DK (1) DK0896525T3 (de)
ES (1) ES2205210T3 (de)
HU (1) HUP9901575A3 (de)
IL (1) IL126701A (de)
NO (1) NO984999L (de)
NZ (1) NZ332669A (de)
WO (1) WO1997040819A1 (de)

Families Citing this family (110)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6060069A (en) * 1991-05-20 2000-05-09 Dura Pharmaceuticals, Inc. Pulmonary delivery of pharmaceuticals
EP0940154B1 (de) * 1991-07-02 2007-04-18 Nektar Therapeutics Abgabevorrichtung für nebelförmige Medikamente
US6681767B1 (en) * 1991-07-02 2004-01-27 Nektar Therapeutics Method and device for delivering aerosolized medicaments
CN1318104C (zh) 1994-09-21 2007-05-30 耐科塔医药公司 送料管组件
ES2205210T3 (es) * 1996-04-29 2004-05-01 Quadrant Technologies Ltd. Procedimientos de inhalacion de polvos secos.
US6433040B1 (en) 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US6946117B1 (en) 1997-09-29 2005-09-20 Nektar Therapeutics Stabilized preparations for use in nebulizers
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
HRP20000608A2 (en) 1998-03-16 2001-04-30 Inhale Therapeutic Syst Aerosolized active agent delivery
US6257233B1 (en) 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
US7056504B1 (en) 1998-08-27 2006-06-06 Massachusetts Institute Of Technology Rationally designed heparinases derived from heparinase I and II
UA73924C2 (en) * 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
JP2000217917A (ja) * 1999-01-27 2000-08-08 Unisia Jecs Corp 吸入式投薬器
JP4824170B2 (ja) 1999-04-23 2011-11-30 マサチューセッツ インスティテュート オブ テクノロジー ポリマーを表記するためのシステムおよび方法
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6606992B1 (en) 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
US7305986B1 (en) * 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US7464706B2 (en) * 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
AU4351201A (en) * 2000-03-08 2001-09-17 Massachusetts Inst Technology Heparinase iii and uses thereof
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
PT1280520E (pt) 2000-05-10 2014-12-16 Novartis Ag Pós à base de fosfolípidos para administração de fármacos
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
WO2002013897A2 (en) 2000-08-14 2002-02-21 Advanced Inhalation Research, Inc. Inhalation device and method
CA2422059C (en) 2000-09-12 2012-05-15 Massachusetts Institute Of Technology Methods and products related to low molecular weight heparin
AU2002224408B2 (en) 2000-10-18 2007-08-23 Massachusetts Institute Of Technology Methods and products related to pulmonary delivery of polysaccharides
EP1370318B1 (de) 2001-03-15 2005-07-20 The Government of the United States of America, as represented by the Secretary, Department of Health & Human Services Vernebler mit kühlkammer
US6766799B2 (en) 2001-04-16 2004-07-27 Advanced Inhalation Research, Inc. Inhalation device
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
US7766013B2 (en) 2001-06-05 2010-08-03 Alexza Pharmaceuticals, Inc. Aerosol generating method and device
US7585493B2 (en) 2001-05-24 2009-09-08 Alexza Pharmaceuticals, Inc. Thin-film drug delivery article and method of use
EP1392262A1 (de) * 2001-05-24 2004-03-03 Alexza Molecular Delivery Corporation Verabreichung von arzneimittel-estern durch inhalation
WO2003024514A1 (en) 2001-09-19 2003-03-27 Advent Pharmaceuticals Pty Ltd An inhaler
ES2364636T3 (es) 2001-12-19 2011-09-08 Novartis Ag Administración pulmonar de aminoglucósidos.
GB0217199D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicament dispenser
GB0201677D0 (en) 2002-01-25 2002-03-13 Glaxo Group Ltd Medicament dispenser
US6705316B2 (en) 2002-03-11 2004-03-16 Battelle Pulmonary Therapeutics, Inc. Pulmonary dosing system and method
SI1494732T1 (sl) 2002-03-20 2008-08-31 Mannking Corp Inhalacijski aparat
DK1485154T3 (da) * 2002-03-20 2008-08-04 Alkermes Inc Pulverinhalationsindretning
US7185651B2 (en) 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
GB0217198D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicament dispenser
EP1534368A1 (de) * 2002-07-25 2005-06-01 Glaxo Group Limited Medikamentenspender
WO2004011067A1 (en) * 2002-07-25 2004-02-05 Glaxo Group Limited Medicament dispenser
GB0217196D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicament dispenser
US7913688B2 (en) * 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
GB0308771D0 (en) * 2003-04-16 2003-05-21 Univ Loughborough Pulmonary drug delivery
CN100381083C (zh) 2003-04-29 2008-04-16 韩力 一种非可燃性电子喷雾香烟
JP2007516149A (ja) 2003-05-21 2007-06-21 アレックザ ファーマシューティカルズ， インコーポレイテッド 基板温度の均一性を制御する方法、および、内蔵式加熱ユニットおよびそれを使用する薬剤供給ユニット
GB0313604D0 (en) * 2003-06-12 2003-07-16 Britannia Pharmaceuticals Ltd Delivery device for powdered medicament
GB0317374D0 (en) * 2003-07-24 2003-08-27 Glaxo Group Ltd Medicament dispenser
DK1699434T3 (da) 2003-09-02 2011-05-30 Norton Healthcare Ltd Fremgangsmåde til fremstilling af et lægemiddel
GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
CA2555390C (en) 2004-02-19 2014-08-05 Coley Pharmaceutical Group, Inc. Immunostimulatory viral rna oligonucleotides
CA2561845C (en) * 2004-04-02 2014-03-25 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention Aerosol delivery systems and methods
JP2007533387A (ja) 2004-04-21 2007-11-22 イノベータ バイオメド リミテッド 吸入器
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
US7540286B2 (en) 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
EP1781360A1 (de) 2004-08-12 2007-05-09 Alexza Pharmaceuticals, Inc. Aerosol-arzneiabgabevorrichtung mit perkussiv aktivierten wärmepackungen
GB0418278D0 (en) * 2004-08-16 2004-09-15 Glaxo Group Ltd Medicament dispenser
KR101273120B1 (ko) 2004-08-20 2013-06-13 맨카인드 코포레이션 다이케토피페라진 합성의 촉매 작용
BR122019022692B1 (pt) 2004-08-23 2023-01-10 Mannkind Corporation Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo
ATE555823T1 (de) * 2004-09-16 2012-05-15 Giampiero Cossi Einweg-monodosis-inhalator für pulverförmige medikamente
US8337815B2 (en) * 2004-12-23 2012-12-25 Discovery Laboratories, Inc. Pulmonary surfactant formulations
GB0515584D0 (en) * 2005-07-28 2005-09-07 Glaxo Group Ltd Medicament dispenser
KR101486829B1 (ko) 2005-09-14 2015-01-29 맨카인드 코포레이션 결정질 미립자 표면에 대한 활성제의 친화력의 증가를 기반으로 하는 약물 제제의 방법
PT1991678E (pt) 2006-02-15 2015-11-25 Adiutide Pharmaceuticals Gmbh Composições e métodos para formulações de oligonucleótidos
EP1986679B1 (de) 2006-02-22 2017-10-25 MannKind Corporation Verfahren zur verbesserung der pharmazeutischen eigenschaften von mikropartikeln mit diketopiperazin und einem wirkstoff
GB0622827D0 (en) * 2006-11-15 2006-12-27 Glaxo Group Ltd Sheet driver for use in a drug dispenser
EP2121088B1 (de) 2007-03-09 2016-07-13 Alexza Pharmaceuticals, Inc. Erhitzungseinheit zur verwendung in einer arzneimittelabgabevorrichtung
WO2008156586A2 (en) * 2007-06-12 2008-12-24 Alkermes, Inc. Inhalation device for powdered substances
WO2008151796A2 (de) * 2007-06-15 2008-12-18 Boehringer Ingelheim International Gmbh Inhaler
EP2082762A1 (de) 2008-01-24 2009-07-29 Boehringer Ingelheim International Gmbh Inhalator
BRPI0910875B8 (pt) * 2008-03-27 2021-06-22 Mannkind Corp sistema de inalação de pó seco
TWI677355B (zh) 2008-06-13 2019-11-21 美商曼凱公司 用於藥物傳輸之乾粉吸入器及系統
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2421385T3 (es) 2008-06-20 2013-09-02 Mannkind Corp Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
CA2732840C (en) 2008-09-26 2016-07-05 Oriel Therapeutics, Inc. Dry powder inhalers with dual piercing members and related devices and methods
CN102159270B (zh) 2008-09-26 2014-07-02 奥里尔治疗公司 一种带有具有气道盘沟槽的气道盘的吸入器和相关的气道盘和方法
WO2010039202A2 (en) * 2008-10-01 2010-04-08 Oriel Therapeutics, Inc. Dry powder inhalers with rotating piercing mechanisms and related devices and methods
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
UA97784C2 (ru) 2009-02-23 2012-03-12 Джапан Тобакко Инк. Ненагреваемое устройство для всасывания табачного аромата
EP2676695A3 (de) * 2009-03-11 2017-03-01 MannKind Corporation Vorrichtung, System und Verfahren zur Messung des Widerstandes eines Inhalators
MY186975A (en) 2009-06-12 2021-08-26 Mannkind Corp Diketopiperazine microparticles with defined specific surface areas
WO2011039646A2 (en) 2009-09-30 2011-04-07 Inserm (Institut National De La Sante Et De La Recherche Medicale) Papilloma virus -like particles for targeted gene delivery
US9016147B2 (en) 2009-11-03 2015-04-28 Mannkind Corporation Apparatus and method for simulating inhalation efforts
MX359281B (es) 2010-06-21 2018-09-21 Mannkind Corp Sistema y metodos para suministrar un farmaco en polvo seco.
US8925726B2 (en) 2011-04-01 2015-01-06 Mannkind Corporation Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
CA2852536A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
CA2878457C (en) 2012-07-12 2021-01-19 Mannkind Corporation Dry powder drug delivery systems and methods
KR101466616B1 (ko) * 2012-10-11 2014-11-28 한미약품 주식회사 건조분말 흡입장치
EP2911690A1 (de) 2012-10-26 2015-09-02 MannKind Corporation Inhalierbare influenza-impfstoffzusammensetzungen und verfahren
US8545878B1 (en) 2012-11-09 2013-10-01 Civitas Therapeutics, Inc. Capsules containing high doses of levodopa for pulmonary use
BR112015010601B1 (pt) 2012-11-09 2022-07-19 Civitas Therapeutics, Inc. Composição farmacêutica e uso da composição
US10034988B2 (en) * 2012-11-28 2018-07-31 Fontem Holdings I B.V. Methods and devices for compound delivery
EP2970149B1 (de) 2013-03-15 2019-08-21 MannKind Corporation Mikrokristalline diketopiperazinzusammensetzungen und verfahren
EP3021834A1 (de) 2013-07-18 2016-05-25 MannKind Corporation Hitzestabile pharmazeutische trockenpulverzusammensetzungen und verfahren
CN105517607A (zh) 2013-08-05 2016-04-20 曼金德公司 吹入设备和方法
US10194693B2 (en) 2013-09-20 2019-02-05 Fontem Holdings 1 B.V. Aerosol generating device
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
EP3191162B1 (de) 2014-09-10 2022-02-23 Fontem Holdings 1 B.V. Verfahren und vorrichtungen zur modulierung des luftstroms in abgabevorrichtungen
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
CA2965759C (en) 2014-10-31 2023-12-12 Glaxosmithkline Intellectual Property Development Limited Powdered polypeptides with decreased disulfide impurities comprising divalent cationic materials
EP3247235B1 (de) 2015-01-22 2020-09-02 Fontem Holdings 1 B.V. Elektronische verdampfervorrichtungen
IT201600093878A1 (it) 2016-09-19 2018-03-19 Hollycon Italy Pte Ltd S R L Inalatore monodose a perdere per medicinali in polvere
WO2018071435A1 (en) 2016-10-11 2018-04-19 Microdose Therapeutx, Inc. Inhaler and methods of use thereof
US12214118B2 (en) 2018-02-02 2025-02-04 Alexza Pharmaceuticals, Inc. Electrical condensation aerosol device

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB248400A (de) * 1925-02-28 1926-11-18 Societe Francaise Des Films Herault
US3831606A (en) * 1971-02-19 1974-08-27 Alza Corp Auto inhaler
IT1220979B (it) * 1981-06-04 1990-06-21 Lofarma Farma Lab Capsule contenenti un allergene e procedimento per la loro preparazione
GB8432063D0 (en) * 1984-12-19 1985-01-30 Riker Laboratories Inc Physically modified steroids
CA2058764A1 (en) * 1989-04-28 1990-10-29 Peter D. Hodson Dry powder inhalation device
US5176132A (en) * 1989-05-31 1993-01-05 Fisons Plc Medicament inhalation device and formulation
US5492112A (en) * 1991-05-20 1996-02-20 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5327883A (en) * 1991-05-20 1994-07-12 Dura Pharmaceuticals, Inc. Apparatus for aerosolizing powdered medicine and process and using
US5469843A (en) * 1991-11-12 1995-11-28 Minnesota Mining And Manufacturing Company Inhalation device
RO113214B1 (ro) * 1992-10-19 1998-05-29 Dura Pharma Inc Inhalator de pulbere uscata
SE9203743D0 (sv) * 1992-12-11 1992-12-11 Astra Ab Efficient use
US5354934A (en) * 1993-02-04 1994-10-11 Amgen Inc. Pulmonary administration of erythropoietin
US5792057A (en) * 1993-05-21 1998-08-11 Aradigm Corporation Ventilation imaging using a fine particle aerosol generator
US5388574A (en) * 1993-07-29 1995-02-14 Ingebrethsen; Bradley J. Aerosol delivery article
JPH0753358A (ja) * 1993-08-17 1995-02-28 Teijin Ltd 吸入剤
US5524613A (en) * 1993-08-25 1996-06-11 Habley Medical Technology Corporation Controlled multi-pharmaceutical inhaler
US5522385A (en) * 1994-09-27 1996-06-04 Aradigm Corporation Dynamic particle size control for aerosolized drug delivery
US5503869A (en) * 1994-10-21 1996-04-02 Glaxo Wellcome Inc. Process for forming medicament carrier for dry powder inhalator
US5645051A (en) * 1995-04-21 1997-07-08 Dura Pharmaceuticals, Inc. Unit dose dry powder inhaler
US5622166A (en) * 1995-04-24 1997-04-22 Dura Pharmaceuticals, Inc. Dry powder inhaler delivery system
ES2205210T3 (es) * 1996-04-29 2004-05-01 Quadrant Technologies Ltd. Procedimientos de inhalacion de polvos secos.

Also Published As

Publication number Publication date
DE69724420D1 (de) 2003-10-02
NO984999D0 (no) 1998-10-27
DE69724420T2 (de) 2004-06-09
EP0896525B1 (de) 2003-08-27
JP2009148586A (ja) 2009-07-09
WO1997040819A1 (en) 1997-11-06
US6116237A (en) 2000-09-12
BR9709748A (pt) 2000-01-11
AU2737197A (en) 1997-11-19
CA2252814A1 (en) 1997-11-06
ES2205210T3 (es) 2004-05-01
CZ343798A3 (cs) 1999-02-17
HUP9901575A2 (hu) 1999-08-30
AU724503B2 (en) 2000-09-21
JP2000510109A (ja) 2000-08-08
NZ332669A (en) 1999-02-25
IL126701A (en) 2001-08-08
EP0896525A4 (de) 2001-01-10
NO984999L (no) 1998-10-27
HUP9901575A3 (en) 1999-11-29
DK0896525T3 (da) 2003-12-01
IL126701A0 (en) 1999-08-17
EP0896525A1 (de) 1999-02-17

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