ATE247118T1 - Imidazo(1,2-a)(pyrrolo, thieno oder furano)(3,2- d)azepinderivate, zubereitungen und ihre verwendung - Google Patents

Imidazo(1,2-a)(pyrrolo, thieno oder furano)(3,2- d)azepinderivate, zubereitungen und ihre verwendung

Info

Publication number: ATE247118T1
Authority: AT; Austria
Prior art keywords: 4alkyl; substituted; hydroxycarbonyl; represents hydrogen; 4alkyloxy
Prior art date: 1991-06-13

Application number

AT92911643T

Other languages

English (en)

Inventor

Frans Eduard Janssens

Gaston Stanislas Marcell Diels

Joseph Elisabeth Leenaerts

Ludwig Paul Cooymans

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-06-13

Filing date

1992-06-09

Publication date

2003-08-15

1992-06-09 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2003-08-15 Application granted granted Critical

2003-08-15 Publication of ATE247118T1 publication Critical patent/ATE247118T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pulmonology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Paper (AREA)
Detergent Compositions (AREA)

AT92911643T 1991-06-13 1992-06-09 Imidazo(1,2-a)(pyrrolo, thieno oder furano)(3,2- d)azepinderivate, zubereitungen und ihre verwendung ATE247118T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US71448791A	1991-06-13	1991-06-13
PCT/EP1992/001331 WO1992022553A1 (en)	1991-06-13	1992-06-09	IMIDAZO[1,2-a](PYRROLO, THIENO OR FURANO)[3,2-d]AZEPINE DERIVATIVES, COMPOSITIONS AND METHODS OF USE

Publications (1)

Publication Number	Publication Date
ATE247118T1 true ATE247118T1 (de)	2003-08-15

Family

ID=24870247

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92911643T ATE247118T1 (de)	1991-06-13	1992-06-09	Imidazo(1,2-a)(pyrrolo, thieno oder furano)(3,2- d)azepinderivate, zubereitungen und ihre verwendung

Country Status (26)

Country	Link
US (1)	US5461050A (de)
EP (2)	EP0588859B1 (de)
JP (1)	JP3182421B2 (de)
KR (1)	KR100247504B1 (de)
CN (1)	CN1033587C (de)
AT (1)	ATE247118T1 (de)
AU (1)	AU652841B2 (de)
CA (1)	CA2102889C (de)
DE (1)	DE69233161T2 (de)
ES (1)	ES2204892T3 (de)
FI (1)	FI104077B (de)
HR (1)	HRP920156A2 (de)
HU (1)	HU221013B1 (de)
IE (1)	IE921919A1 (de)
IL (1)	IL101851A (de)
MA (1)	MA22554A1 (de)
MX (1)	MX9202860A (de)
NO (2)	NO934493D0 (de)
NZ (1)	NZ242775A (de)
PL (1)	PL170376B1 (de)
SI (1)	SI9200104A (de)
TN (1)	TNSN92049A1 (de)
TW (1)	TW218382B (de)
WO (1)	WO1992022553A1 (de)
ZA (1)	ZA924327B (de)
ZM (1)	ZM2892A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL101850A (en) *	1991-06-13	1996-01-31	Janssen Pharmaceutica Nv	11-(4-Piperidinyl)-imidazo (2,1-b) (3) benzazepine derivatives their preparation and pharmaceutical compositions containing them
GR1001385B (el) *	1992-10-12	1993-10-29	Janssen Pharmaceutica Nv	Παράγωγα ιμιδαζο 1,2-α (πυρρολο,?ειενο η φουρανο) 3,2-d αζεπίνης συν?έσεις και μέ?οδοι χρήσεως.
NZ258552A (en) *	1992-12-04	1996-07-26	Janssen Pharmaceutica Nv	Azepine derivatives; compounds, preparation of and pharmaceutical compositions containing such compounds
PL176528B1 (pl) *	1992-12-04	1999-06-30	Janssen Pharmaceutica Nv	Nowy związek, pochodna triazolo (pirolo,tieno lub furano) azepiny
FI960157L (fi) *	1993-07-13	1996-01-12	Janssen Pharmaceutica Nv	Allergianvastaisia imidatsoatsepiineja
TW382017B (en)	1995-12-27	2000-02-11	Janssen Pharmaceutica Nv	1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives
TW527186B (en)	1996-03-19	2003-04-11	Janssen Pharmaceutica Nv	Fused imidazole derivatives as multidrug resistance modulators
JP3882224B2 (ja) *	1996-05-31	2007-02-14	旭硝子株式会社	パロキセチンの製造方法
AU1146099A (en)	1997-09-18	1999-04-05	Janssen Pharmaceutica N.V.	Fused imidazole derivatives for improving oral bioavailability of pharmaceuticalagents
UA74537C2 (uk)	1998-12-19	2006-01-16	Янссен Фармацевтика Н.В.	Антигістамінні спіросполуки
TWI225488B (en) *	1999-12-21	2004-12-21	Janssen Pharmaceutica Nv	Derivatives of homopiperidinyl substituted benzimidazole analogues
EP1401838B1 (de)	2001-06-12	2014-03-26	Janssen Pharmaceutica NV	Substituierte tetrazyklische imidazol derivate, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen sie einthaltend und ihre verwendung als arzneimittel
AU2004259009A1 (en) *	2003-07-23	2005-02-03	Exelixis, Inc.	Azepine derivatives as pharmaceutical agents
ES2350647T3 (es)	2005-03-08	2011-01-25	Janssen Pharmaceutica Nv	Derivados de diaza-espiro-[4.4]-nonano como antagonistas de neuroquininas (nk1).
TWI498115B (zh) *	2007-12-27	2015-09-01	Daiichi Sankyo Co Ltd	咪唑羰基化合物
CN103570731B (zh) *	2012-07-30	2016-05-18	中国科学院广州生物医药与健康研究院	嘧啶并三环或嘧啶并四环类化合物及其药用组合物和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4148903A (en) *	1977-07-28	1979-04-10	Merck & Co., Inc.	Antipsychotic, antiserotonin and antihistaminic pyrrolo[2,1-b][3]benzazepines
GB8900380D0 (en) *	1989-01-09	1989-03-08	Janssen Pharmaceutica Nv	2-aminopyrimidinone derivatives
IL101850A (en) *	1991-06-13	1996-01-31	Janssen Pharmaceutica Nv	11-(4-Piperidinyl)-imidazo (2,1-b) (3) benzazepine derivatives their preparation and pharmaceutical compositions containing them

1992
- 1992-05-13 IL IL10185192A patent/IL101851A/en not_active IP Right Cessation
- 1992-05-15 NZ NZ242775A patent/NZ242775A/en unknown
- 1992-05-16 CN CN92104830A patent/CN1033587C/zh not_active Expired - Fee Related
- 1992-05-21 TW TW081103953A patent/TW218382B/zh active
- 1992-06-09 AU AU19011/92A patent/AU652841B2/en not_active Ceased
- 1992-06-09 DE DE69233161T patent/DE69233161T2/de not_active Expired - Fee Related
- 1992-06-09 CA CA002102889A patent/CA2102889C/en not_active Expired - Fee Related
- 1992-06-09 WO PCT/EP1992/001331 patent/WO1992022553A1/en not_active Ceased
- 1992-06-09 JP JP51073492A patent/JP3182421B2/ja not_active Expired - Fee Related
- 1992-06-09 US US08/150,121 patent/US5461050A/en not_active Expired - Lifetime
- 1992-06-09 PL PL92301819A patent/PL170376B1/pl unknown
- 1992-06-09 HU HU9303554A patent/HU221013B1/hu not_active IP Right Cessation
- 1992-06-09 EP EP92911643A patent/EP0588859B1/de not_active Expired - Lifetime
- 1992-06-09 EP EP92201665A patent/EP0518434A1/de active Pending
- 1992-06-09 KR KR1019930703789A patent/KR100247504B1/ko not_active Expired - Fee Related
- 1992-06-09 ES ES92911643T patent/ES2204892T3/es not_active Expired - Lifetime
- 1992-06-09 AT AT92911643T patent/ATE247118T1/de not_active IP Right Cessation
- 1992-06-10 HR HR920156A patent/HRP920156A2/hr not_active Application Discontinuation
- 1992-06-11 MA MA22844A patent/MA22554A1/fr unknown
- 1992-06-12 ZM ZM2892A patent/ZM2892A1/xx unknown
- 1992-06-12 SI SI19929200104A patent/SI9200104A/sl not_active IP Right Cessation
- 1992-06-12 ZA ZA924327A patent/ZA924327B/xx unknown
- 1992-06-12 MX MX9202860A patent/MX9202860A/es not_active IP Right Cessation
- 1992-06-15 TN TNTNSN92049A patent/TNSN92049A1/fr unknown
- 1992-07-01 IE IE191992A patent/IE921919A1/en not_active Application Discontinuation
1993
- 1993-12-09 NO NO934493D patent/NO934493D0/no unknown
- 1993-12-09 NO NO934493A patent/NO300689B1/no not_active IP Right Cessation
- 1993-12-10 FI FI935557A patent/FI104077B/fi active

Also Published As

Publication number	Publication date
NO300689B1 (no)	1997-07-07
JP3182421B2 (ja)	2001-07-03
DE69233161D1 (de)	2003-09-18
HUT70428A (en)	1995-10-30
NO934493D0 (no)	1993-12-09
EP0588859A1 (de)	1994-03-30
FI935557A7 (fi)	1993-12-10
AU1901192A (en)	1993-01-12
CA2102889C (en)	2002-11-26
TW218382B (de)	1994-01-01
US5461050A (en)	1995-10-24
DE69233161T2 (de)	2004-05-27
EP0588859B1 (de)	2003-08-13
HRP920156A2 (en)	1995-12-31
FI104077B1 (fi)	1999-11-15
TNSN92049A1 (fr)	1993-06-08
ZM2892A1 (en)	1994-05-25
EP0518434A1 (de)	1992-12-16
CN1033587C (zh)	1996-12-18
IE921919A1 (en)	1992-12-16
IL101851A (en)	1996-05-14
HU9303554D0 (en)	1994-04-28
CN1068116A (zh)	1993-01-20
NO934493L (no)	1994-01-04
SI9200104A (en)	1992-12-31
PL170376B1 (pl)	1996-12-31
MX9202860A (es)	1992-12-01
IL101851A0 (en)	1992-12-30
CA2102889A1 (en)	1992-12-14
HU221013B1 (hu)	2002-07-29
MA22554A1 (fr)	1992-12-31
KR100247504B1 (ko)	2000-05-01
NZ242775A (en)	1995-03-28
ES2204892T3 (es)	2004-05-01
WO1992022553A1 (en)	1992-12-23
JPH06507890A (ja)	1994-09-08
FI935557A0 (fi)	1993-12-10
ZA924327B (en)	1993-12-13
FI104077B (fi)	1999-11-15
AU652841B2 (en)	1994-09-08

Publication	Publication Date	Title
HU9303553D0 (en)	1994-04-28	Imidazo[2,1-b][3]benzazepine derivatives, compositions and methods of use
ATE247118T1 (de)	2003-08-15	Imidazo(1,2-a)(pyrrolo, thieno oder furano)(3,2- d)azepinderivate, zubereitungen und ihre verwendung
PL300066A1 (en)	1994-02-21	Novel 7-(substituted)-8-(substituted)-9-(substituted amino)-6-demethyl-6-deoxy-tyetracyclines, methods of obtaining them and pharmaceutical composition
AU2174288A (en)	1989-03-09	Lactam derivatives
NZ232283A (en)	1991-08-27	Substituted imidazo(1,2-b)pyridazine derivatives; pharmaceutical compositions and preparatory processes
CA2150805A1 (en)	1994-06-23	Antiallergic imidazo[1,2-a](pyrrolo, thieno or furano)[2,3-d]azepine derivatives
EP0306300A3 (en)	1990-08-16	Pyrrolo(1,2-a)imidazole and imidazo(1,2-a)pyridine derivatives and their use as 5-lipoxygenase pathway inhibitors
NO174670C (no)	1994-06-15	Analogifremgangsmåte for fremstilling av terapeutisk aktive 1H-pyrido(4,3-b)indol-1-on-derivater
IE880318L (en)	1988-08-06	Tricyclic triazolopyrimidines
YU61292A (sh)	1994-09-09	Imidazo(1,2,-a)(3)(pirolo, tieno ili furano)(3,2-a)azepinski derivati i preparati

Legal Events

Date	Code	Title	Description
2004-02-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties