ATE150793T1 - Markierte verbindungen zur verwendung in einem diagnostischen atemtest - Google Patents
Markierte verbindungen zur verwendung in einem diagnostischen atemtestInfo
- Publication number
- ATE150793T1 ATE150793T1 AT91911157T AT91911157T ATE150793T1 AT E150793 T1 ATE150793 T1 AT E150793T1 AT 91911157 T AT91911157 T AT 91911157T AT 91911157 T AT91911157 T AT 91911157T AT E150793 T1 ATE150793 T1 AT E150793T1
- Authority
- AT
- Austria
- Prior art keywords
- microorganisms
- breath test
- oils
- produce
- labeled
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003921 oil Substances 0.000 abstract 5
- 244000005700 microbiome Species 0.000 abstract 4
- 239000000758 substrate Substances 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 abstract 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 abstract 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 abstract 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000005642 Oleic acid Substances 0.000 abstract 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 abstract 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
- A61K51/1206—Administration of radioactive gases, aerosols or breath tests
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B1/00—Production of fats or fatty oils from raw materials
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/06—Lysis of microorganisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6463—Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/946—Microorganisms using algae
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Urology & Nephrology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Optics & Photonics (AREA)
- Dispersion Chemistry (AREA)
- Atmospheric Sciences (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Virology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/525,820 US5164308A (en) | 1990-05-21 | 1990-05-21 | Preparation of labelled triglyceride oils by cultivation of microorganisms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE150793T1 true ATE150793T1 (de) | 1997-04-15 |
Family
ID=24094735
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91911157T ATE150793T1 (de) | 1990-05-21 | 1991-05-13 | Markierte verbindungen zur verwendung in einem diagnostischen atemtest |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US5164308A (de) |
| EP (1) | EP0533775B1 (de) |
| JP (1) | JPH05507275A (de) |
| AT (1) | ATE150793T1 (de) |
| CA (1) | CA2083041C (de) |
| DE (1) | DE69125373T2 (de) |
| WO (1) | WO1991018105A1 (de) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3354582B2 (ja) * | 1991-09-30 | 2002-12-09 | サントリー株式会社 | オメガ9系高度不飽和脂肪酸およびこれを含有する脂質の製造方法 |
| US6569640B1 (en) * | 1993-03-12 | 2003-05-27 | Aphios Corporation | Method of fractionation of biologically-derived materials using critical fluids |
| US6334997B1 (en) | 1994-03-25 | 2002-01-01 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
| CA2186371A1 (en) * | 1994-03-25 | 1995-10-05 | Robert T. Foster | Enhancement of the efficacy of dihydropyridines by deuteration |
| AU7731696A (en) * | 1995-11-15 | 1997-06-05 | Martek Corporation | Photosynthetic production of stable isotopically labeled recombinant proteins |
| US5707602A (en) * | 1996-03-25 | 1998-01-13 | Meretek Diagnostics | Measurement of gastric emptying |
| JP2000510513A (ja) * | 1996-05-15 | 2000-08-15 | ヒスト―ブロカデス・ベスローテン・フェンノートシャップ | 低ステロール且つ高トリグリセライドの微生物性油を得るための極性溶媒によるステロール抽出 |
| US5785949A (en) * | 1996-09-05 | 1998-07-28 | Meretek Diagnostics | Measurement of liquid phase gastric emptying |
| CA2249173C (en) * | 1997-10-06 | 2008-12-16 | Tokyo Gas Co., Ltd. | Diagnostic agent for liver function |
| CA2250485C (en) * | 1997-10-21 | 2008-04-29 | Tokyo Gas Co., Ltd. | Diagnostic agent for diabetes |
| US6284219B1 (en) | 1998-06-30 | 2001-09-04 | Phenome Sciences Inc. | In vivo determination of metabolic function for use in therapy management |
| EP1006198A1 (de) * | 1998-12-01 | 2000-06-07 | Meretek Diagnostics | Ein nicht-invasives Verfahren zur funktionellen Feststellung von Säuglingen und Kindern mit einer ererbten metabolischen Störung |
| US6291241B1 (en) * | 1999-03-29 | 2001-09-18 | Trevor Percival Castor | Methods for making Hypericum fractions and St. John's Wort products |
| AU2001252559B2 (en) * | 2000-05-02 | 2005-09-15 | Otsuka Pharmaceutical Co., Ltd. | Preparations for evaluating eliminative ability of stomach |
| EP1404861A4 (de) * | 2001-06-05 | 2006-02-01 | Philadelphia Children Hospital | Verfahren und kits zur diagnose einer fett-malabsorptionsstörung mit ursache im pankreas |
| US20050281745A1 (en) * | 2002-03-22 | 2005-12-22 | Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center | Stable isotope based dynamic metabolic profiling of living organisms for characterization of metabolic diseases, drug testing and drug development |
| JP4088097B2 (ja) * | 2002-04-26 | 2008-05-21 | サントリー株式会社 | 高度不飽和脂肪酸含有脂質の製造方法 |
| WO2005015201A1 (en) * | 2003-08-06 | 2005-02-17 | Children's Hospital Medical Center | Use of non-absorbable fat in determining dietary fat absorption |
| US20090041662A1 (en) * | 2005-02-23 | 2009-02-12 | Irie Yasuo | Method for Monitoring Patient or Subject Compliance with Medical Prescriptions, and Formulation for Use in the Method |
| US20060188444A1 (en) * | 2005-02-23 | 2006-08-24 | Otsuka Pharmaceutical Co., Ltd. | Method for monitoring patient or subject compliance with medical prescriptions, and formulation for use in the method |
| CA2602183C (en) | 2005-03-18 | 2014-05-06 | Microbia, Inc. | Production of carotenoids in oleaginous yeast and fungi |
| CN104745486B (zh) | 2005-06-07 | 2018-01-16 | 帝斯曼营养品股份公司 | 生产脂质和抗氧化剂的真核微生物 |
| PT1920786E (pt) | 2005-07-25 | 2011-12-28 | Otsuka Pharma Co Ltd | Preparação oral para avaliar a capacidade metabólica da pirimidina |
| EP2043970B1 (de) * | 2006-07-05 | 2018-04-18 | Centre National De La Recherche Scientifique (C.N.R.S.) | Co-katalysiertes eisen-kupfer-verfahren für kohlenstoff-kohlenstoff- oder kohlenstoff-heteroatom-bindung |
| WO2008129358A2 (en) | 2006-08-01 | 2008-10-30 | Ocean Nutrition Canada Ltd. | Oil producing microbes and methods of modification thereof |
| FR2904773B1 (fr) * | 2006-08-11 | 2008-11-07 | Lvmh Rech | Composition cosmetique amincissante contenant un extrait de biomasse de l'algue neochloris oleoabundans |
| US8691555B2 (en) | 2006-09-28 | 2014-04-08 | Dsm Ip Assests B.V. | Production of carotenoids in oleaginous yeast and fungi |
| CN101765661B (zh) | 2007-06-01 | 2014-08-06 | 索拉兹米公司 | 在微生物中生产油 |
| RU2361922C1 (ru) * | 2007-11-19 | 2009-07-20 | Лимнологический институт Сибирского отделения Российской академии наук | Способ получения изотопномеченых 13c полиненасыщенных жирных кислот |
| KR101607235B1 (ko) * | 2008-04-09 | 2016-03-29 | 솔라짐, 인코포레이티드 | 미생물 바이오매스 및 미생물 오일의 직접적인 화학적 개질 |
| US20100303989A1 (en) | 2008-10-14 | 2010-12-02 | Solazyme, Inc. | Microalgal Flour |
| US20160324167A1 (en) | 2008-10-14 | 2016-11-10 | Terravia Holdings, Inc. | Novel microalgal food compositions |
| US8809037B2 (en) | 2008-10-24 | 2014-08-19 | Bioprocessh20 Llc | Systems, apparatuses and methods for treating wastewater |
| KR101763878B1 (ko) | 2008-11-28 | 2017-08-01 | 테라비아 홀딩스 인코포레이티드 | 종속영양성 미생물에서 맞춤 오일의 생성 |
| US8709750B2 (en) * | 2008-12-15 | 2014-04-29 | Cavitation Technologies, Inc. | Method for processing an algae medium containing algae microorganisms to produce algal oil and by-products |
| MX2012001126A (es) * | 2009-07-28 | 2012-04-20 | Joule Unltd Technologies Inc | Fotobiorreactores, sistemas de captacion de energia solar, y metodos de regulacion termica. |
| US20110177564A1 (en) * | 2010-01-15 | 2011-07-21 | Massachusetts Institute Of Technology | Bioprocess and microbe engineering for total carbon utilization in biofuel production |
| JP5996527B2 (ja) | 2010-05-28 | 2016-09-21 | テラヴィア ホールディングス, インコーポレイテッド | 用途に応じた油を含む食品成分 |
| MX354145B (es) | 2010-11-03 | 2018-02-14 | Terravia Holdings Inc | Aceites microbianos con puntos de fluidez reducidos, fluidos dielectricos producidos a partir de estos y metodos relacionados. |
| AU2012212079B2 (en) | 2011-02-02 | 2016-07-28 | Corbion Biotech, Inc. | Tailored oils produced from recombinant oleaginous microorganisms |
| US8846352B2 (en) | 2011-05-06 | 2014-09-30 | Solazyme, Inc. | Genetically engineered microorganisms that metabolize xylose |
| JP2014185189A (ja) * | 2011-07-14 | 2014-10-02 | Ajinomoto Co Inc | 脂肪酸類の製造法 |
| SG11201406711TA (en) | 2012-04-18 | 2014-11-27 | Solazyme Inc | Tailored oils |
| JP6352188B2 (ja) | 2012-08-20 | 2018-07-04 | 大塚製薬株式会社 | 糖代謝能の測定方法及びそれに使用する組成物 |
| US10098371B2 (en) | 2013-01-28 | 2018-10-16 | Solazyme Roquette Nutritionals, LLC | Microalgal flour |
| DK2970926T3 (en) | 2013-03-13 | 2018-04-16 | Dsm Nutritional Products Ag | GENMANIPULATION OF MICROorganisms |
| ES2754246T3 (es) | 2013-03-15 | 2020-04-16 | Otsuka Pharma Co Ltd | Composición para su uso en un método para medir la razón de combustión azúcar/ácido graso |
| WO2014176515A2 (en) * | 2013-04-26 | 2014-10-30 | Solazyme, Inc. | Low polyunsaturated fatty acid oils and uses thereof |
| FR3009619B1 (fr) | 2013-08-07 | 2017-12-29 | Roquette Freres | Compositions de biomasse de microalgues riches en proteines de qualite sensorielle optimisee |
| MX369685B (es) | 2013-10-04 | 2019-11-19 | Terravia Holdings Inc | Aceites adaptables. |
| CN106574255A (zh) | 2014-07-10 | 2017-04-19 | 泰拉瑞亚控股公司 | 酮脂酰acp合酶基因及其用途 |
| AR104042A1 (es) | 2015-03-26 | 2017-06-21 | Mara Renewables Corp | Producción de alta densidad de biomasa y aceite utilizando glicerol en bruto |
| HK1254383A1 (zh) | 2015-07-13 | 2019-07-19 | MARA Renewables Corporation | 增强木糖的微藻代谢 |
| US10851395B2 (en) | 2016-06-10 | 2020-12-01 | MARA Renewables Corporation | Method of making lipids with improved cold flow properties |
| US20240216321A1 (en) | 2022-12-02 | 2024-07-04 | Dsm Ip Assets B.V. | Fermentatively-produced retinoid containing compositions, and the methdos of making and using the same |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1342098A (en) * | 1971-03-12 | 1973-12-25 | Atomic Energy Authority Uk | 14c-labelled compounds |
| US4485173A (en) * | 1981-01-19 | 1984-11-27 | Cpc International Inc. | Preparation of fats and oils |
| JPS62146597A (ja) * | 1985-12-20 | 1987-06-30 | Idemitsu Petrochem Co Ltd | 菌体中の油脂成分の分離方法 |
| JPH0763381B2 (ja) * | 1987-03-06 | 1995-07-12 | 財団法人相模中央化学研究所 | 微生物によるエイコサペンタエン酸含有脂質の製法 |
| JPS63273484A (ja) * | 1987-04-30 | 1988-11-10 | Yoshihara Seiyu Kk | 高パルミトオレイン酸含有脂質の製造方法 |
| JPS63295527A (ja) * | 1987-05-27 | 1988-12-01 | Nippon Oil & Fats Co Ltd | 高度不飽和脂肪酸の濃縮分離方法 |
| GB8715428D0 (en) * | 1987-07-01 | 1987-08-26 | Univ Dundee | Organic compounds |
| KR890701751A (ko) * | 1987-07-20 | 1989-12-21 | 원본 미기재 | 오메가-3(n-3) 지질의 미생물 생성물 |
| JPH0225447A (ja) * | 1988-07-13 | 1990-01-26 | Nippon Oil & Fats Co Ltd | 高度不飽和脂肪酸類の製造方法 |
| JPH02146597A (ja) * | 1988-11-28 | 1990-06-05 | Yamaha Corp | 電子楽器の楽音制御方法 |
| JP2834251B2 (ja) * | 1990-01-22 | 1998-12-09 | 旭化成工業株式会社 | コンクリート板用吊込み治具 |
| JPH03273484A (ja) * | 1990-03-23 | 1991-12-04 | Sanyo Electric Co Ltd | 自動販売機 |
-
1990
- 1990-05-21 US US07/525,820 patent/US5164308A/en not_active Expired - Fee Related
-
1991
- 1991-05-13 AT AT91911157T patent/ATE150793T1/de not_active IP Right Cessation
- 1991-05-13 WO PCT/US1991/003335 patent/WO1991018105A1/en not_active Ceased
- 1991-05-13 CA CA002083041A patent/CA2083041C/en not_active Expired - Fee Related
- 1991-05-13 JP JP91510426A patent/JPH05507275A/ja active Pending
- 1991-05-13 EP EP91911157A patent/EP0533775B1/de not_active Expired - Lifetime
- 1991-05-13 DE DE69125373T patent/DE69125373T2/de not_active Expired - Fee Related
-
1992
- 1992-09-24 US US07/936,248 patent/US5376540A/en not_active Expired - Lifetime
-
1994
- 1994-11-10 US US08/338,755 patent/US5466434A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5466434A (en) | 1995-11-14 |
| EP0533775A4 (en) | 1993-06-30 |
| DE69125373T2 (de) | 1997-09-25 |
| CA2083041C (en) | 2003-07-22 |
| CA2083041A1 (en) | 1991-11-22 |
| WO1991018105A1 (en) | 1991-11-28 |
| US5164308A (en) | 1992-11-17 |
| JPH05507275A (ja) | 1993-10-21 |
| DE69125373D1 (de) | 1997-04-30 |
| US5376540A (en) | 1994-12-27 |
| EP0533775A1 (de) | 1993-03-31 |
| EP0533775B1 (de) | 1997-03-26 |
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