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AR132695A1 - PROCEDURE FOR THE PREPARATION OF D-THALITOL, D-TAGATOSE AND D-PSYCHOSE - Google Patents

PROCEDURE FOR THE PREPARATION OF D-THALITOL, D-TAGATOSE AND D-PSYCHOSE

Info

Publication number
AR132695A1
AR132695A1 ARP240101233A ARP240101233A AR132695A1 AR 132695 A1 AR132695 A1 AR 132695A1 AR P240101233 A ARP240101233 A AR P240101233A AR P240101233 A ARP240101233 A AR P240101233A AR 132695 A1 AR132695 A1 AR 132695A1
Authority
AR
Argentina
Prior art keywords
thalitol
tagatose
psychose
procedure
preparation
Prior art date
Application number
ARP240101233A
Other languages
Spanish (es)
Inventor
Nicole Staunig
Maria Dupont
Melanie Trobe
Original Assignee
Annikki Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP23173450.0A external-priority patent/EP4464785A1/en
Priority claimed from EP23206404.8A external-priority patent/EP4545646A1/en
Application filed by Annikki Gmbh filed Critical Annikki Gmbh
Publication of AR132695A1 publication Critical patent/AR132695A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/24—Preparation of compounds containing saccharide radicals produced by the action of an isomerase, e.g. fructose
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01001—Alcohol dehydrogenase (1.1.1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01047—Glucose 1-dehydrogenase (1.1.1.47)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y117/00—Oxidoreductases acting on CH or CH2 groups (1.17)
    • C12Y117/01—Oxidoreductases acting on CH or CH2 groups (1.17) with NAD+ or NADP+ as acceptor (1.17.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y501/00—Racemaces and epimerases (5.1)
    • C12Y501/03—Racemaces and epimerases (5.1) acting on carbohydrates and derivatives (5.1.3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La invención consiste en un procedimiento para preparar una solución acuosa que contiene D-talitol, en donde se forma D-psicosa in vitro a partir de D-fructosa, que está disuelta en una solución acuosa, por tratamiento con una epimerasa, tras lo cual la D-psicosa se reduce por tratamiento con una oxidorreductasa dependiente de NAD(P)H in vitro en D-talitol. El D-talitol contenido en la solución acuosa se puede oxidar de manera simple por tratamiento con una oxidorreductasa en D-tagatosa o D-psicosa.The invention relates to a process for preparing an aqueous solution containing D-thalitol, wherein D-psicose is formed in vitro from D-fructose dissolved in an aqueous solution by treatment with an epimerase, after which the D-psicose is reduced to D-thalitol by treatment with an NAD(P)H-dependent oxidoreductase in vitro. The D-thalitol contained in the aqueous solution can be oxidized in a simple manner to D-tagatose or D-psicose by treatment with an oxidoreductase.

ARP240101233A 2023-05-15 2024-05-15 PROCEDURE FOR THE PREPARATION OF D-THALITOL, D-TAGATOSE AND D-PSYCHOSE AR132695A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP23173450.0A EP4464785A1 (en) 2023-05-15 2023-05-15 Process for producing d-talitol, d-tagatose and d-psicose
EP23206404.8A EP4545646A1 (en) 2023-10-27 2023-10-27 Process for the preparation of d-talitol

Publications (1)

Publication Number Publication Date
AR132695A1 true AR132695A1 (en) 2025-07-23

Family

ID=91070269

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP240101233A AR132695A1 (en) 2023-05-15 2024-05-15 PROCEDURE FOR THE PREPARATION OF D-THALITOL, D-TAGATOSE AND D-PSYCHOSE

Country Status (2)

Country Link
AR (1) AR132695A1 (en)
WO (1) WO2024236043A1 (en)

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002612A (en) 1989-07-19 1991-03-26 Biospherics Incorporated Process for manufacturing tagatose
TW572878B (en) 2001-05-11 2004-01-21 Fushimi Pharmaceutical Co Ltd Method for production of sugar alcohol
JP4423363B2 (en) 2004-12-13 2010-03-03 独立行政法人産業技術総合研究所 Novel process for producing D-talitol using D-psicose as a raw material
TW201343623A (en) 2012-02-07 2013-11-01 Annikki Gmbh Process for the enzymatic regeneration of redox cofactors
US8802843B2 (en) 2012-05-22 2014-08-12 Orochem Technologies, Inc. Tagatose production using simulated moving bed separation
CN105188362A (en) 2013-03-13 2015-12-23 三井化学Agro株式会社 Composition for enhancing plant disease control effect of monosaccharide
KR101550796B1 (en) 2013-06-05 2015-09-07 씨제이제일제당 (주) Manufacturing method for tagatose
US9150938B2 (en) 2013-06-12 2015-10-06 Orochem Technologies, Inc. Tagatose production from deproteinized whey and purification by continuous chromatography
KR101638024B1 (en) 2014-10-22 2016-07-20 씨제이제일제당(주) Composition for preparation of tagatose and manufacturing method for tagatose from fructose
US10196626B2 (en) 2015-07-29 2019-02-05 Cj Cheiljedang Corporation Hexuronate C4-epimerase mutant with improved conversion activity, and method for producing D-tagatose by using same
CN108374031A (en) 2015-10-02 2018-08-07 博努莫斯生化有限责任公司 The enzymatic production of D-Tag
KR101723007B1 (en) 2016-02-29 2017-04-04 씨제이제일제당(주) A method of manufacturing high purity d-psicose
ES2950576T3 (en) 2016-06-30 2023-10-11 Cj Cheiljedang Corp Novel heat-resistant fructose-6-phosphate-3-epimerase and method of producing allulose by using it
KR102065155B1 (en) 2016-12-08 2020-02-11 주식회사 삼양사 Production of psciose
PE20191355A1 (en) 2016-12-14 2019-10-01 Bonumose Llc ENZYMATIC PRODUCTION OF D-ALLULOSE
MX2019011730A (en) 2017-03-31 2020-12-07 Cj Cheiljedang Corp Composition for producing tagatose and production method of tagatose using same.
CA3058415C (en) 2017-03-31 2024-10-29 Cj Cheiljedang Corporation Composition for producing tagatose and method of producing tagatose using the same
US11408018B2 (en) 2017-08-31 2022-08-09 Cj Cheiljedang Corporation Fructose-C4-epimerase and preparation method for producing tagatose using the same
WO2019231393A1 (en) 2018-05-31 2019-12-05 Ngee Ann Polytechnic D-psicose production using probiotic microorganisms
JP7197086B2 (en) 2018-09-11 2022-12-27 国立大学法人 香川大学 Microorganism producing allitol and D-talitol from D-allulose and method for producing allitol and D-talitol using the same

Also Published As

Publication number Publication date
WO2024236043A1 (en) 2024-11-21

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