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AR100771A1 - Métodos de tratamiento que utilizan el ácido 1,2,4-oxadiazolbenzoico - Google Patents

Métodos de tratamiento que utilizan el ácido 1,2,4-oxadiazolbenzoico

Info

Publication number
AR100771A1
AR100771A1 ARP150101807A ARP150101807A AR100771A1 AR 100771 A1 AR100771 A1 AR 100771A1 AR P150101807 A ARP150101807 A AR P150101807A AR P150101807 A ARP150101807 A AR P150101807A AR 100771 A1 AR100771 A1 AR 100771A1
Authority
AR
Argentina
Prior art keywords
acid
oxadiazolbenzoic
treatment methods
nmmps
disease
Prior art date
Application number
ARP150101807A
Other languages
English (en)
Original Assignee
Ptc Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ptc Therapeutics Inc filed Critical Ptc Therapeutics Inc
Publication of AR100771A1 publication Critical patent/AR100771A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Reivindicación 1: Un método para el tratamiento, prevención, recuperación o control de una enfermedad de mucopolisacaridosis con mediación de mutación interruptora (nmMPS) asociada con una mutación interruptora o un codón de terminación prematura, que comprende la administración de una cantidad efectiva de ácido 3-[5-(2-fluoro-fenil)-[1,2,4]oxadiazol-3-il]benzoico o una sal farmacéuticamente aceptable de este a un paciente que tiene la enfermedad de nmMPS.
ARP150101807A 2014-06-06 2015-06-05 Métodos de tratamiento que utilizan el ácido 1,2,4-oxadiazolbenzoico AR100771A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462009100P 2014-06-06 2014-06-06

Publications (1)

Publication Number Publication Date
AR100771A1 true AR100771A1 (es) 2016-11-02

Family

ID=54767414

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP150101807A AR100771A1 (es) 2014-06-06 2015-06-05 Métodos de tratamiento que utilizan el ácido 1,2,4-oxadiazolbenzoico

Country Status (4)

Country Link
US (1) US20170196842A1 (es)
AR (1) AR100771A1 (es)
TW (1) TW201625241A (es)
WO (1) WO2015188037A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9873677B2 (en) 2014-03-06 2018-01-23 Ptc Therapeutics, Inc. Pharmaceutical compositions and salts of a 1,2,4-oxadiazole benzoic acid
MX2018005361A (es) 2015-10-30 2018-06-07 Ptc Therapeutics Inc Metodos para tratar epilepsia.
WO2019101709A1 (en) 2017-11-23 2019-05-31 Universita' Degli Studi Di Palermo Oxadiazole derivatives for the treatment of genetic diseases due to nonsense mutations

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1874306E (pt) * 2005-04-08 2012-10-11 Ptc Therapeutics Inc Composições de um 1,2,4-oxadiazole oralmente activo para terapia de supressão de mutações sem sentido (ou nonsense)
ES2710854T3 (es) * 2010-08-05 2019-04-29 Univ Lille Compuesto útil para el tratamiento de enfermedades mediadas por una mutación sin sentido y composición farmacéutica que comprende dicho compuesto

Also Published As

Publication number Publication date
US20170196842A1 (en) 2017-07-13
TW201625241A (zh) 2016-07-16
WO2015188037A1 (en) 2015-12-10

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Legal Events

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