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AR107935A1 - Uso del compuesto 6-(4-(2,3-dimetilfenoxi)piperidin-1-il)metil)pirimidino-2,4(1h,3h)-diona o una sal farmacéuticamente aceptable del mismo para preparar un medicamento, combinación y composición farmacéutica que comprende dicho compuesto - Google Patents

Uso del compuesto 6-(4-(2,3-dimetilfenoxi)piperidin-1-il)metil)pirimidino-2,4(1h,3h)-diona o una sal farmacéuticamente aceptable del mismo para preparar un medicamento, combinación y composición farmacéutica que comprende dicho compuesto

Info

Publication number
AR107935A1
AR107935A1 ARP170100695A ARP170100695A AR107935A1 AR 107935 A1 AR107935 A1 AR 107935A1 AR P170100695 A ARP170100695 A AR P170100695A AR P170100695 A ARP170100695 A AR P170100695A AR 107935 A1 AR107935 A1 AR 107935A1
Authority
AR
Argentina
Prior art keywords
compound
dimethylphenoxy
methyl
piperidin
prepare
Prior art date
Application number
ARP170100695A
Other languages
English (en)
Inventor
Kevin Pethe
Provencio Jorge Esquivias
Pichel Julia Castro
Robert H Bates
Aguirre David Barros
Pages Luis Ballell
Original Assignee
Glaxosmithkline Ip Dev Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Ip Dev Ltd filed Critical Glaxosmithkline Ip Dev Ltd
Publication of AR107935A1 publication Critical patent/AR107935A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Uso en terapia del compuesto 6-(4-(2,3-dimetilfenoxi)piperidin-1-il)metil)pirimidino-2,4-(1H,3H)-diona o una sal farmacéuticamente aceptable del mismo, incluido el uso como agente anti-micobacteriano para preparar un medicamento, por ejemplo en el tratamiento de tuberculosis. Combinaciones que contienen el compuesto 6-(4-(2,3-dimetilfenoxi)piperidin-1-il)metil)pirimidino-2,4(1H,3H)-diona con otros agentes terapéuticos y composiciones farmacéuticas que comprenden el compuesto 6-(4-(2,3-dimetilfenoxi)piperidin-1-il)metil)pirimidino-2,4(1H,3H)-diona, o sales de dicho compuesto 6-(4-(2,3-dimetilfenoxi)piperidin-1-il)metil)pirimidino-2,4(1H,3H)-diona.
ARP170100695A 2016-03-22 2017-03-21 Uso del compuesto 6-(4-(2,3-dimetilfenoxi)piperidin-1-il)metil)pirimidino-2,4(1h,3h)-diona o una sal farmacéuticamente aceptable del mismo para preparar un medicamento, combinación y composición farmacéutica que comprende dicho compuesto AR107935A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP16382124 2016-03-22

Publications (1)

Publication Number Publication Date
AR107935A1 true AR107935A1 (es) 2018-06-28

Family

ID=55752236

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP170100695A AR107935A1 (es) 2016-03-22 2017-03-21 Uso del compuesto 6-(4-(2,3-dimetilfenoxi)piperidin-1-il)metil)pirimidino-2,4(1h,3h)-diona o una sal farmacéuticamente aceptable del mismo para preparar un medicamento, combinación y composición farmacéutica que comprende dicho compuesto

Country Status (24)

Country Link
US (1) US10624893B2 (es)
EP (1) EP3432887B1 (es)
JP (1) JP6961608B2 (es)
KR (1) KR102479358B1 (es)
CN (1) CN108883114B (es)
AR (1) AR107935A1 (es)
AU (1) AU2017237380B2 (es)
CA (1) CA3018611C (es)
CY (1) CY1123527T1 (es)
DK (1) DK3432887T3 (es)
ES (1) ES2833929T3 (es)
HR (1) HRP20201861T1 (es)
HU (1) HUE051349T2 (es)
LT (1) LT3432887T (es)
PL (1) PL3432887T3 (es)
PT (1) PT3432887T (es)
RS (1) RS61103B1 (es)
RU (1) RU2756208C2 (es)
SI (1) SI3432887T1 (es)
SM (1) SMT202000636T1 (es)
TW (1) TW201808295A (es)
UY (1) UY37161A (es)
WO (1) WO2017162591A1 (es)
ZA (1) ZA201806012B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110004074B (zh) * 2019-02-28 2021-06-18 北京蛋白质组研究中心 一种利用silac标记耻垢分枝杆菌蛋白质的方法及其专用培养基
EP4271679A4 (en) * 2021-02-01 2024-09-11 The Global Alliance for TB Drug Development, Inc. AMORPHOUS FORM OF PRETOMANIDES
US11793808B2 (en) 2021-02-22 2023-10-24 Mannkind Corp. Compositions of clofazimine, combinations comprising them, processes for their preparation, uses and methods comprising them
CN115902217B (zh) * 2023-03-08 2023-06-16 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） 一种牛副结核病间接elisa检测试剂盒及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2188196C2 (ru) * 1998-05-26 2002-08-27 Ашкинази Римма Ильинична N-замещенные производные 5-оксииминобарбитуровой кислоты
WO2000034250A1 (en) * 1998-12-04 2000-06-15 Rimma Illiinichna Ashkinazi 2,4-dioxo-5-arylidenimino-1,3-pyrimidines
EP1655288A1 (en) * 2004-11-05 2006-05-10 Institut Pasteur Aryl pyrimidyl compounds, pharmaceutical compositions comprising them, their use as antimicrobial agents
CN102971301B (zh) * 2010-05-31 2015-07-22 科学与工业研究委员会 抗结核药剂

Also Published As

Publication number Publication date
TW201808295A (zh) 2018-03-16
RU2018136747A (ru) 2020-04-22
EP3432887A1 (en) 2019-01-30
CA3018611C (en) 2024-02-27
LT3432887T (lt) 2020-12-10
PL3432887T3 (pl) 2021-05-17
KR20180122006A (ko) 2018-11-09
HRP20201861T1 (hr) 2021-01-08
US10624893B2 (en) 2020-04-21
US20190091224A1 (en) 2019-03-28
ES2833929T3 (es) 2021-06-16
CY1123527T1 (el) 2022-03-24
JP6961608B2 (ja) 2021-11-05
AU2017237380A1 (en) 2018-09-27
WO2017162591A1 (en) 2017-09-28
RU2756208C2 (ru) 2021-09-28
KR102479358B1 (ko) 2022-12-19
EP3432887B1 (en) 2020-09-02
RS61103B1 (sr) 2020-12-31
ZA201806012B (en) 2020-02-26
UY37161A (es) 2017-09-29
DK3432887T3 (da) 2020-11-09
BR112018069487A2 (pt) 2019-02-12
HUE051349T2 (hu) 2021-03-01
AU2017237380B2 (en) 2019-12-19
SI3432887T1 (sl) 2020-12-31
SMT202000636T1 (it) 2021-01-05
PT3432887T (pt) 2020-12-04
CN108883114A (zh) 2018-11-23
JP2019512524A (ja) 2019-05-16
CA3018611A1 (en) 2017-09-28
RU2018136747A3 (es) 2020-05-15
CN108883114B (zh) 2021-08-24

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