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AR090470A1 - Vacuna contra el virus sincicial respiratorio (rsv) - Google Patents

Vacuna contra el virus sincicial respiratorio (rsv)

Info

Publication number
AR090470A1
AR090470A1 ARP130100941A ARP130100941A AR090470A1 AR 090470 A1 AR090470 A1 AR 090470A1 AR P130100941 A ARP130100941 A AR P130100941A AR P130100941 A ARP130100941 A AR P130100941A AR 090470 A1 AR090470 A1 AR 090470A1
Authority
AR
Argentina
Prior art keywords
adenovirus
rsv
region
vaccine against
against respiratory
Prior art date
Application number
ARP130100941A
Other languages
English (en)
Inventor
Radosvic Katarina
H H V Custers Jerme
Vellinga Jort
N Widjojoatmodjo Myra
Original Assignee
Crucell Holland Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crucell Holland Bv filed Critical Crucell Holland Bv
Publication of AR090470A1 publication Critical patent/AR090470A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/18011—Paramyxoviridae
    • C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Reivindicación 1: Una vacuna contra virus sincitial respiratorio (VSR), que comprende un adenovirus humano recombinante de serotipo 35 que comprende ácido nucleico que codifica para una proteína F de VSR o un fragmento de la misma. Reivindicación 5: Una vacuna de acuerdo a cualquiera de las reivindicaciones precedentes, en donde el adenovirus humano recombinante tiene una eliminación en la región E1, una eliminación en la región E3, o una eliminación tanto en la región E1 como en la región E3 del genoma adenoviral. Reivindicación 15: Un método para hacer una vacuna contra virus sincitial respiratorio (VSR), que comprende proveer un adenovirus humano recombinante de serotipo 35 que comprende ácido nucleico que codifica para una proteína F de VSR o un fragmento de la misma, propagar dicho adenovirus recombinante en un cultivo de células huéspedes, aislar y purificar el adenovirus recombinante, y formular el adenovirus recombinante en una composición farmacéuticamente aceptable.
ARP130100941A 2012-03-22 2013-03-22 Vacuna contra el virus sincicial respiratorio (rsv) AR090470A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12160682 2012-03-22

Publications (1)

Publication Number Publication Date
AR090470A1 true AR090470A1 (es) 2014-11-12

Family

ID=49221877

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP130100940A AR090469A1 (es) 2012-03-22 2013-03-22 Vacuna contra el virus sincicial respiratorio (rsv)
ARP130100941A AR090470A1 (es) 2012-03-22 2013-03-22 Vacuna contra el virus sincicial respiratorio (rsv)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ARP130100940A AR090469A1 (es) 2012-03-22 2013-03-22 Vacuna contra el virus sincicial respiratorio (rsv)

Country Status (15)

Country Link
EP (2) EP2827894B1 (es)
JP (2) JP5805908B2 (es)
KR (2) KR102023791B1 (es)
CN (2) CN104334188B (es)
AP (2) AP2014007994A0 (es)
AR (2) AR090469A1 (es)
AU (2) AU2013237424B2 (es)
BR (1) BR112014023196B1 (es)
CA (2) CA2867955C (es)
EA (2) EA026620B1 (es)
MY (2) MY169352A (es)
NZ (2) NZ630753A (es)
SG (2) SG11201405804YA (es)
TW (2) TWI624545B (es)
WO (2) WO2013139911A1 (es)

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CN114845733A (zh) * 2020-08-22 2022-08-02 俄罗斯联邦卫生部的联邦国家预算机构“以名誉院士N.F.加马列亚命名的国家流行病学和微生物学研究中心” 抗严重急性呼吸综合征病毒SARS-CoV-2的表达载体
RU2731356C9 (ru) * 2020-08-22 2021-10-05 федеральное государственное бюджетное учреждение "Национальный исследовательский центр эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи" Министерства здравоохранения Российской Федерации Экспрессионный вектор для создания иммунобиологического средства для индукции специфического иммунитета против вируса тяжелого острого респираторного синдрома SARS-CoV-2 (варианты)
CA3152662A1 (en) * 2020-08-22 2021-04-22 Federal State Budgetary Institution "National Research Centre For Epidemiology And Microbiology Named After The Honorary Academician N.F. Gamaleya" Of The Ministry Of Health Of The Russian Federation Pharmaceutical agent for inducing specific immunity against sars-cov-2
CN112226444B (zh) * 2020-08-25 2022-11-04 北京交通大学 呼吸道合胞病毒全长融合前融合糖蛋白核苷酸序列、重组腺病毒载体及其应用产品
CN112220921B (zh) * 2020-08-25 2022-08-16 北京交通大学 一种针对呼吸道合胞病毒感染的组合疫苗
KR20230165807A (ko) * 2021-04-05 2023-12-05 가부시끼 가이샤 구보다 관리기 제어 시스템
CN117018175A (zh) * 2022-05-10 2023-11-10 康希诺生物股份公司 一种呼吸道合胞病毒腺病毒载体疫苗及其制备方法和应用
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Also Published As

Publication number Publication date
EA201491752A1 (ru) 2015-02-27
TWI624545B (zh) 2018-05-21
AU2013237424B2 (en) 2017-07-06
KR102050616B1 (ko) 2019-12-03
CA2867950C (en) 2023-02-21
WO2013139911A1 (en) 2013-09-26
CA2867955A1 (en) 2013-09-26
SG11201405804YA (en) 2014-10-30
TW201341531A (zh) 2013-10-16
MY169352A (en) 2019-03-25
AP2014007994A0 (en) 2014-10-31
CN104334188A (zh) 2015-02-04
JP5805908B2 (ja) 2015-11-10
AP2014007993A0 (en) 2014-10-31
CN105431169B (zh) 2019-04-02
BR112014023196B1 (pt) 2021-09-08
KR20140138769A (ko) 2014-12-04
EP2827894A1 (en) 2015-01-28
KR102023791B1 (ko) 2019-09-23
CN105431169A (zh) 2016-03-23
AU2013237429B2 (en) 2015-07-23
MY169331A (en) 2019-03-21
BR112014023196A2 (es) 2017-06-20
AR090469A1 (es) 2014-11-12
SG11201405803PA (en) 2014-11-27
NZ630649A (en) 2016-12-23
TW201343669A (zh) 2013-11-01
EA026504B1 (ru) 2017-04-28
TWI640534B (zh) 2018-11-11
EP2827895B1 (en) 2017-08-09
CA2867950A1 (en) 2013-09-26
EA026620B1 (ru) 2017-04-28
CN104334188B (zh) 2016-08-24
EA201491754A1 (ru) 2014-12-30
AU2013237424A1 (en) 2014-10-16
KR20140138765A (ko) 2014-12-04
EP2827894B1 (en) 2017-05-17
JP5845376B2 (ja) 2016-01-20
AU2013237429A1 (en) 2014-10-09
WO2013139916A1 (en) 2013-09-26
NZ630753A (en) 2016-12-23
JP2015512380A (ja) 2015-04-27
EP2827895A1 (en) 2015-01-28
JP2015519295A (ja) 2015-07-09
CA2867955C (en) 2023-02-07

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