AR094018A1 - Inhibidores de corrientes funny (if) para utilizar en un metodo de tratamiento y/o prevencion de la enfermedad cardiaca en caninos - Google Patents
Inhibidores de corrientes funny (if) para utilizar en un metodo de tratamiento y/o prevencion de la enfermedad cardiaca en caninosInfo
- Publication number
- AR094018A1 AR094018A1 ARP130104746A ARP130104746A AR094018A1 AR 094018 A1 AR094018 A1 AR 094018A1 AR P130104746 A ARP130104746 A AR P130104746A AR P130104746 A ARP130104746 A AR P130104746A AR 094018 A1 AR094018 A1 AR 094018A1
- Authority
- AR
- Argentina
- Prior art keywords
- arrhythmias
- prevention
- treatment
- funny current
- caninos
- Prior art date
Links
- 208000019622 heart disease Diseases 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title abstract 3
- 230000002265 prevention Effects 0.000 title abstract 2
- 208000020446 Cardiac disease Diseases 0.000 title 1
- 206010003119 arrhythmia Diseases 0.000 abstract 3
- 230000006793 arrhythmia Effects 0.000 abstract 3
- OBUFMJDDZTXJPY-NRFANRHFSA-N 3-[[(3s)-1-[2-(3,4-dimethoxyphenyl)ethyl]piperidin-3-yl]methyl]-7,8-dimethoxy-2,5-dihydro-1h-3-benzazepin-4-one Chemical compound C1=C(OC)C(OC)=CC=C1CCN1C[C@@H](CN2C(CC3=CC(OC)=C(OC)C=C3CC2)=O)CCC1 OBUFMJDDZTXJPY-NRFANRHFSA-N 0.000 abstract 2
- 206010056370 Congestive cardiomyopathy Diseases 0.000 abstract 2
- 201000010046 Dilated cardiomyopathy Diseases 0.000 abstract 2
- 208000001871 Tachycardia Diseases 0.000 abstract 2
- 229950010208 cilobradine Drugs 0.000 abstract 2
- 208000005907 mitral valve insufficiency Diseases 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- KEDQCFRVSHYKLR-UHFFFAOYSA-N 3-[3-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one Chemical compound C1=C(OC)C(OC)=CC=C1CCN(C)CCCN1C(=O)CC2=CC(OC)=C(OC)C=C2CC1 KEDQCFRVSHYKLR-UHFFFAOYSA-N 0.000 abstract 1
- 206010003130 Arrhythmia supraventricular Diseases 0.000 abstract 1
- 241000282465 Canis Species 0.000 abstract 1
- ACRHBAYQBXXRTO-OAQYLSRUSA-N ivabradine Chemical compound C1CC2=CC(OC)=C(OC)C=C2CC(=O)N1CCCN(C)C[C@H]1CC2=C1C=C(OC)C(OC)=C2 ACRHBAYQBXXRTO-OAQYLSRUSA-N 0.000 abstract 1
- 229960003825 ivabradine Drugs 0.000 abstract 1
- 230000006794 tachycardia Effects 0.000 abstract 1
- 229950003419 zatebradine Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4168—1,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Un bloqueante lᶠ, o una de sus sales farmacéuticamente aceptables para el tratamiento y/o prevención de un paciente canino que sufre de enfermedades cardíacas, con preferencia enfermedades cardíacas tales como cardiomiopatía dilatada (DCM), insuficiencia de la válvula mitral (MI), arritmias, con preferencia taquiarritmias, arritmias con preferencia arritmias atriales, arritmias atrioventriculares nodales y/o taquicardia. Reivindicación 14: El inhibidor de corriente funny (lᶠ) o una de sus sales farmacéuticamente aceptables para usar en un método de acuerdo con cualquiera de las reivindicaciones 12 a 13, caracterizado porque el inhibidor de corriente funny (Iᶠ) se selecciona del grupo que consiste en cilobradina, zatebradina, ivabradina y anilidina, con preferencia es cilobradina.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12197371 | 2012-12-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR094018A1 true AR094018A1 (es) | 2015-07-01 |
Family
ID=47358383
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP130104746A AR094018A1 (es) | 2012-12-14 | 2013-12-13 | Inhibidores de corrientes funny (if) para utilizar en un metodo de tratamiento y/o prevencion de la enfermedad cardiaca en caninos |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20140171415A1 (es) |
| EP (1) | EP2931262A1 (es) |
| AR (1) | AR094018A1 (es) |
| TW (1) | TW201436795A (es) |
| WO (1) | WO2014090842A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2741735A1 (en) | 2011-08-12 | 2014-06-18 | Boehringer Ingelheim Vetmedica GmbH | Funny current (if) inhibitors for use in a method of treating and preventing heart failure in feline |
| WO2017173458A1 (en) * | 2016-04-01 | 2017-10-05 | Swiderski Cyprianna | Compositions and methods targeting hcn channels for breathing therapeutics |
| ES2851923T3 (es) * | 2016-05-20 | 2021-09-09 | Nestle Sa | Triglicéridos de cadena intermedia para el tratamiento de enfermedad degenerativa de la válvula mitral en animales de compañía |
| ES2963110T3 (es) * | 2018-12-27 | 2024-03-25 | Nestle Sa | Composiciones y métodos para el diagnóstico y tratamiento de la enfermedad degenerativa de la válvula mitral en caninos |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5595987A (en) * | 1994-07-22 | 1997-01-21 | The Trustees Of Columbia University In The City Of New York | Method of slowing ventricular arrhythmias using zatebradine |
| EP1762179A1 (en) * | 2005-09-07 | 2007-03-14 | Boehringer Ingelheim Vetmedica Gmbh | Method for improving diagnostic quality in echocardiography |
-
2013
- 2013-12-11 US US14/102,622 patent/US20140171415A1/en not_active Abandoned
- 2013-12-11 EP EP13805843.3A patent/EP2931262A1/en not_active Withdrawn
- 2013-12-11 WO PCT/EP2013/076156 patent/WO2014090842A1/en not_active Ceased
- 2013-12-13 TW TW102146272A patent/TW201436795A/zh unknown
- 2013-12-13 AR ARP130104746A patent/AR094018A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014090842A1 (en) | 2014-06-19 |
| TW201436795A (zh) | 2014-10-01 |
| EP2931262A1 (en) | 2015-10-21 |
| US20140171415A1 (en) | 2014-06-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |