AR072815A1 - COMPOSITIONS AND USES OF ACTIVE ANTIVIRAL PHARMACEUTICAL AGENTS - Google Patents
COMPOSITIONS AND USES OF ACTIVE ANTIVIRAL PHARMACEUTICAL AGENTSInfo
- Publication number
- AR072815A1 AR072815A1 ARP090102719A ARP090102719A AR072815A1 AR 072815 A1 AR072815 A1 AR 072815A1 AR P090102719 A ARP090102719 A AR P090102719A AR P090102719 A ARP090102719 A AR P090102719A AR 072815 A1 AR072815 A1 AR 072815A1
- Authority
- AR
- Argentina
- Prior art keywords
- compositions
- pharmaceutical agents
- pleconaril
- antiviral pharmaceutical
- active antiviral
- Prior art date
Links
- 230000000840 anti-viral effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 239000008177 pharmaceutical agent Substances 0.000 title 1
- KQOXLKOJHVFTRN-UHFFFAOYSA-N pleconaril Chemical compound O1N=C(C)C=C1CCCOC1=C(C)C=C(C=2N=C(ON=2)C(F)(F)F)C=C1C KQOXLKOJHVFTRN-UHFFFAOYSA-N 0.000 abstract 3
- 229960000471 pleconaril Drugs 0.000 abstract 3
- 208000037874 Asthma exacerbation Diseases 0.000 abstract 1
- 241000709661 Enterovirus Species 0.000 abstract 1
- 229940112141 dry powder inhaler Drugs 0.000 abstract 1
- 229940097496 nasal spray Drugs 0.000 abstract 1
- 239000007922 nasal spray Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Otolaryngology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Varias realizaciones del presente proporcionan un método para tratar, reducir o minimizar las exacerbaciones del asma en seres humanos que son PCR+ para un rinovirus, que incluye administrar por inhalacion oral o intranasal una cantidad terapéuticamente efectiva de pleconaril. Reivindicacion 2: El método de la reivindicacion 1, en el que se administra pleconaril mediante un pulverizador nasal. Reivindicacion 16: El método de la reivindicacion 15, en el que se administra pleconaril mediante un inhalador de polvo seco.Several embodiments of the present provide a method for treating, reducing or minimizing asthma exacerbations in humans that are PCR + for a rhinovirus, which includes administering a therapeutically effective amount of pleconaril by oral or intranasal inhalation. Claim 2: The method of claim 1, wherein pleconaril is administered by a nasal spray. Claim 16: The method of claim 15, wherein pleconaril is administered by a dry powder inhaler.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8158308P | 2008-07-17 | 2008-07-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR072815A1 true AR072815A1 (en) | 2010-09-22 |
Family
ID=41119278
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP090102719A AR072815A1 (en) | 2008-07-17 | 2009-07-16 | COMPOSITIONS AND USES OF ACTIVE ANTIVIRAL PHARMACEUTICAL AGENTS |
Country Status (3)
| Country | Link |
|---|---|
| AR (1) | AR072815A1 (en) |
| TW (1) | TW201016215A (en) |
| WO (1) | WO2010009288A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG184430A1 (en) | 2010-04-15 | 2012-11-29 | Biota Scient Management | Compound for treatment of respiratory condition or disease |
| WO2015023524A1 (en) * | 2013-08-15 | 2015-02-19 | Antivirus Therapeutics | Methods and compositions for increasing the effectiveness of antiviral agents |
| EP4241771A3 (en) | 2013-11-08 | 2023-11-22 | Antivirus Therapeutics | Methods and compositions for treating sepsis |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006017505A2 (en) * | 2004-08-04 | 2006-02-16 | Schering Corporation | Pharmaceutical formulations comprising pleconaril for the treatment of airway diseases |
| CA2641616A1 (en) * | 2006-02-09 | 2007-08-23 | Schering Corporation | Pharmaceutical formulations |
| JP2009526064A (en) * | 2006-02-09 | 2009-07-16 | シェーリング コーポレイション | Pharmaceutical formulation |
| EP1981475A2 (en) * | 2006-02-09 | 2008-10-22 | Schering Corporation | Pharmaceutical formulations |
-
2009
- 2009-07-15 TW TW098123936A patent/TW201016215A/en unknown
- 2009-07-16 AR ARP090102719A patent/AR072815A1/en not_active Application Discontinuation
- 2009-07-16 WO PCT/US2009/050794 patent/WO2010009288A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010009288A1 (en) | 2010-01-21 |
| TW201016215A (en) | 2010-05-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |