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AR070353A1 - FERTILITY GENETIC MARKERS - Google Patents

FERTILITY GENETIC MARKERS

Info

Publication number
AR070353A1
AR070353A1 ARP090100425A ARP090100425A AR070353A1 AR 070353 A1 AR070353 A1 AR 070353A1 AR P090100425 A ARP090100425 A AR P090100425A AR P090100425 A ARP090100425 A AR P090100425A AR 070353 A1 AR070353 A1 AR 070353A1
Authority
AR
Argentina
Prior art keywords
ars
bfgl
ngs
bta
btb
Prior art date
Application number
ARP090100425A
Other languages
Spanish (es)
Inventor
Mogens Sando Lund
Bernt Guldbrandtsen
Vivi Hunnicke Nielsen
Christian Bendixen
Soren Svendsen
Bo Thomsen
Bente Flugel Majgren
Original Assignee
Kvaegavlsforeningen Dansire
Univ Aarhus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kvaegavlsforeningen Dansire, Univ Aarhus filed Critical Kvaegavlsforeningen Dansire
Publication of AR070353A1 publication Critical patent/AR070353A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La presente se relaciona con la fertilidad en sujetos bovinos. En particular, se proveen marcadores genéticos para determinar la fertilidad en un sujeto bovino, su descendencia, y se provee asimismo un conjunto de elementos de diagnostico para detectar los marcadores genéticos asociados con la fertilidad en un sujeto bovino. Los métodos comprenden detectar una combinacion específica de dos o más marcadores genéticos indicativos de la fertilidad en una muestra biologica de un sujeto bovino. En particular, en la presente se divulgan numerosos polimorfismos de nucleotidos y marcadores de microsatélites individuales, que se correlacionan con la fertilidad en bovinos. Reivindicacion 1: Un método para determinar la fertilidad en un sujeto bovino, que comprende detectar en una muestra de dicho sujeto bovino la presencia o ausencia de dos o más alelos de marcadores genéticos que están asociados con al menos una característica indicativa de la fertilidad de dicho sujeto bovino y/o la descendencia del mismo, en donde dichos dos o más alelos de marcadores genéticos son polimorfismos de un solo polinucleotido seleccionados del grupo que consiste de Hapmap60827-rs29019866, ARSBFGL-NGS-40979, Hapmap47854-BTA-119090, ARS-BFGL-NGS-114679, Hapmap43841-BTA-34601, Hapmap43407-BTA-93630, Hapmap43407-BTA- 93630, BTB-01536946, ARS-BFGL-NGS-31952, Hapmap44123-BTA-70017, Hapmap50451 -BTA-70851, Hapmap58408-rs29020693, ARS-BFGL-NGS106105, ARS-BFGL-NGS-1461, ARS-BFGL-NGS-106105, ARS-BFGL-NGS-1461, ARS-BFGL-NGS-106105, ARS-BFGL-NGS-1461, ARS-BFGL-NGS-118182, Hapmap27428-BTA-151920, BTB-01182684, BTB-01182684, BTB01347067, UA-IFASA-2717, ARS-BFGL-BAC-15431, BTB-01064770, Hapmap43361-BTA-80384, BTB-01984646, BTA-122483-no-rs, ARS-BFGL-NGS-32233, BTA-74241-no-rs, BTB-01984646, ARS-BFGL-NGS-112793, ARS-BFGL-NGS-57955, ARS-BFGL-NGS-35771, BTA-32111-no-rs, ARS-BFGL-BAC-13827, ARS-BFGL-NGS-110387, ARS-BFGL-BAC-12582, Hapmap57166-rs29020401, ARS-BFGL-NGS-110104, ARS-BFGL-NGS-55024, BTA-119014-no-rs, UA-IFASA-4025, ARS-BFGL-NGS-49, BTB-01394423, ARS-BFGL-NGS-57955, ARS-BFGL-BAC-13827, ARS-BFGL-NGS-111603, Hapmap41181-BTA-120938, BTA-32160-no-rs, BTA-03159-no-rs, ARS-BFGL-NGS-35771, ARS-BFGL-NGS-433, BTB-00752386, ARS-BFGL-NGS-109970, ARS-BFGL-NGS-103549, ARS-BFGL-NGS-109970, ARS-BFGL-NGS-100910, Hapmap41280-BTA-50090, Hapmap41280-BTA-50090, Hapmap41280-BTA-50090, Hapmap41280-BTA-50090, BTB-01263022, Hapmap54222-rs29017183, BTA-53883-no-rs, ARS-BFGL-NGS-31638, ARS-BFGL-BAC-30072, ARS-BFGL-NGS-21335, Hapmap52259-rs29019756, BTA-57993-no-rs, ARS-BFGL-NGS-35716, ARS-BFGL-NGS-112101, y/o ARS-BFGL-NGS-112101, y/o un alelo de un marcador genético que está acoplado genéticamente a cualquiera de dichos polimorfismos de un solo polinucleotido.This is related to fertility in bovine subjects. In particular, genetic markers are provided to determine fertility in a bovine subject, their offspring, and a set of diagnostic elements to detect genetic markers associated with fertility in a bovine subject is also provided. The methods comprise detecting a specific combination of two or more genetic markers indicative of fertility in a biological sample of a bovine subject. In particular, numerous nucleotide polymorphisms and individual microsatellite markers, which correlate with bovine fertility, are disclosed herein. Claim 1: A method for determining fertility in a bovine subject, comprising detecting in a sample of said bovine subject the presence or absence of two or more alleles of genetic markers that are associated with at least one characteristic indicative of said fertility. bovine subject and / or offspring thereof, wherein said two or more alleles of genetic markers are single polynucleotide polymorphisms selected from the group consisting of Hapmap60827-rs29019866, ARSBFGL-NGS-40979, Hapmap47854-BTA-119090, ARS- BFGL-NGS-114679, Hapmap43841-BTA-34601, Hapmap43407-BTA-93630, Hapmap43407-BTA- 93630, BTB-01536946, ARS-BFGL-NGS-31952, Hapmap44123-BTA-70017, Hapmap58451-868 rs29020693, ARS-BFGL-NGS106105, ARS-BFGL-NGS-1461, ARS-BFGL-NGS-106105, ARS-BFGL-NGS-1461, ARS-BFGL-NGS-106105, ARS-BFGL-NGS-1461, ARS BFGL-NGS-118182, Hapmap27428-BTA-151920, BTB-01182684, BTB-01182684, BTB01347067, UA-IFASA-2717, ARS-BFGL-BAC-15431, BTB-010 64770, Hapmap43361-BTA-80384, BTB-01984646, BTA-122483-no-rs, ARS-BFGL-NGS-32233, BTA-74241-no-rs, BTB-01984646, ARS-BFGL-NGS-112793, ARS- BFGL-NGS-57955, ARS-BFGL-NGS-35771, BTA-32111-no-rs, ARS-BFGL-BAC-13827, ARS-BFGL-NGS-110387, ARS-BFGL-BAC-12582, Hapmap57166-rs29020401, ARS-BFGL-NGS-110104, ARS-BFGL-NGS-55024, BTA-119014-no-rs, UA-IFASA-4025, ARS-BFGL-NGS-49, BTB-01394423, ARS-BFGL-NGS-57955, ARS-BFGL-BAC-13827, ARS-BFGL-NGS-111603, Hapmap41181-BTA-120938, BTA-32160-no-rs, BTA-03159-no-rs, ARS-BFGL-NGS-35771, ARS-BFGL- NGS-433, BTB-00752386, ARS-BFGL-NGS-109970, ARS-BFGL-NGS-103549, ARS-BFGL-NGS-109970, ARS-BFGL-NGS-100910, Hapmap41280-BTA-50090, Hapmap-1280-BTA 50090, Hapmap41280-BTA-50090, Hapmap41280-BTA-50090, BTB-01263022, Hapmap54222-rs29017183, BTA-53883-no-rs, ARS-BFGL-NGS-31638, ARS-BFGL-BAC-30072, ARS-BFGL72 NGS-21335, Hapmap52259-rs29019756, BTA-57993-no-rs, ARS-BFGL-NGS-35716, ARS-BFGL-NGS-112101, and / or ARS-BFGL-NGS-112101, and / or an allele of a genetic marker that is ac genetically opted to any of said single polynucleotide polymorphisms.

ARP090100425A 2008-02-08 2009-02-06 FERTILITY GENETIC MARKERS AR070353A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200800180 2008-02-08

Publications (1)

Publication Number Publication Date
AR070353A1 true AR070353A1 (en) 2010-03-31

Family

ID=40473800

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP090100425A AR070353A1 (en) 2008-02-08 2009-02-06 FERTILITY GENETIC MARKERS

Country Status (2)

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AR (1) AR070353A1 (en)
WO (1) WO2009097862A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120004112A1 (en) * 2008-08-19 2012-01-05 Aarhus Universitet Methods for determining a breeding value based on a plurality of genetic markers
CN102676514B (en) * 2012-05-30 2013-07-17 中国农业大学 Single nucleotide polymorphism (SNP) mark relevant with milk production traits of Chinese Holstein dairy cattle and application thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007081788A2 (en) * 2006-01-05 2007-07-19 Washington State University Research Foundation Calpastatin markers for fertility and longevity
EP1996722A4 (en) * 2006-03-30 2009-09-09 Innovative Dairy Products Pty Chromosomal blocks as markers for traits

Also Published As

Publication number Publication date
WO2009097862A1 (en) 2009-08-13

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