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AR070140A1 - Composicion que comprende un derivado de nitrooxina de acetaminofeno y una droga anticonvulsiva para el tratamiento del dolor neuropatico - Google Patents

Composicion que comprende un derivado de nitrooxina de acetaminofeno y una droga anticonvulsiva para el tratamiento del dolor neuropatico

Info

Publication number
AR070140A1
AR070140A1 ARP090100071A ARP090100071A AR070140A1 AR 070140 A1 AR070140 A1 AR 070140A1 AR P090100071 A ARP090100071 A AR P090100071A AR P090100071 A ARP090100071 A AR P090100071A AR 070140 A1 AR070140 A1 AR 070140A1
Authority
AR
Argentina
Prior art keywords
treatment
neuropathic pain
composition
pain
nitrooxine
Prior art date
Application number
ARP090100071A
Other languages
English (en)
Inventor
Francesco Impagnatiello
Juan F Herrero
Francesca Benedini
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Publication of AR070140A1 publication Critical patent/AR070140A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Las composiciones de la presente pueden usarse en el tratamiento del dolor neuropático, en particular, el dolor neuropático diabético, el síndrome doloroso post-infarto, el dolor provocado por un tratamiento quimioterapéutico o el dolor que surge de infecciones de agentes virales. Reivindicacion 1: Una composicion caracterizada porque comprende (a) un paracetamol que libera oxido nítrico y (b) una droga anticonvulsiva seleccionada entre gabapentina, pregabalina y tiagabina. Reivindicacion 3: La composicion de acuerdo con la reivindicacion 1 caracterizada porque el paracetamol que libera oxido nítrico es 4-(N-acetilamino)fenil éster de ácido 4-(nitrooxi)butanoico y la droga anticonvulsiva es gabapentina.
ARP090100071A 2008-01-10 2009-01-09 Composicion que comprende un derivado de nitrooxina de acetaminofeno y una droga anticonvulsiva para el tratamiento del dolor neuropatico AR070140A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08150156 2008-01-10

Publications (1)

Publication Number Publication Date
AR070140A1 true AR070140A1 (es) 2010-03-17

Family

ID=40853501

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP090100071A AR070140A1 (es) 2008-01-10 2009-01-09 Composicion que comprende un derivado de nitrooxina de acetaminofeno y una droga anticonvulsiva para el tratamiento del dolor neuropatico

Country Status (6)

Country Link
US (1) US20100286264A1 (es)
EP (1) EP2229161A2 (es)
JP (1) JP2011509267A (es)
AR (1) AR070140A1 (es)
CA (1) CA2706028A1 (es)
WO (1) WO2009087005A2 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010108843A1 (en) * 2009-03-27 2010-09-30 Nicox S.A. Use of nitrooxyderivative of paracetamol for the treatment of muscular dystrophies
CN110461338A (zh) * 2017-03-28 2019-11-15 北卡罗来纳大学查佩尔希尔分校 作为可生物降解抗菌支架的释放一氧化氮的聚氨基糖苷类和其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1319202B1 (it) * 2000-10-12 2003-09-26 Nicox Sa Farmaci per le malattie a base infiammatoria.
ITMI20011308A1 (it) * 2001-06-21 2002-12-21 Nicox Sa Farmaci per il dolore cronico
GB0415076D0 (en) * 2004-07-05 2004-08-04 Sandoz Ind Products S A Process for the preparation of gabapentin

Also Published As

Publication number Publication date
WO2009087005A4 (en) 2010-03-04
CA2706028A1 (en) 2009-07-16
US20100286264A1 (en) 2010-11-11
JP2011509267A (ja) 2011-03-24
EP2229161A2 (en) 2010-09-22
WO2009087005A3 (en) 2009-12-23
WO2009087005A2 (en) 2009-07-16

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