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AR078257A2 - COMPOSITION TO IMMUNIZE MAMMALS AGAINST THE AFTOSA VIRUS - Google Patents

COMPOSITION TO IMMUNIZE MAMMALS AGAINST THE AFTOSA VIRUS

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Publication number
AR078257A2
AR078257A2 ARP100103213A AR078257A2 AR 078257 A2 AR078257 A2 AR 078257A2 AR P100103213 A ARP100103213 A AR P100103213A AR 078257 A2 AR078257 A2 AR 078257A2
Authority
AR
Argentina
Prior art keywords
dna sequence
composition according
fragment
sequence encoding
transgenic plant
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Santos Maria Jose Dus
Andres Wigdorovitz
Fernando Ardila
Raul Rios
Pascual Franzone
Consuelo Carrillo
Manuel Borca
Original Assignee
Inst Nac De Tecnologia Agropecuaria Inta
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nac De Tecnologia Agropecuaria Inta filed Critical Inst Nac De Tecnologia Agropecuaria Inta
Priority to ARP100103213 priority Critical patent/AR078257A2/en
Publication of AR078257A2 publication Critical patent/AR078257A2/en

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Reivindicacion 1: Una composicion para inmunizar mamíferos contra el virus de la aftosa, caracterizada porque comprende al menos una planta transgénica o una parte de una planta transgénica que expresa cápsides vacías del virus de la aftosa, donde dicha planta transgénica o parte de .la misma comprende en su genoma una construccion de ADN que comprende al menos una secuencia de ADN que codifica a la poliproteína precursora P1 unida a una secuencia de ADN que codifica a la proteasa autocatalítica 2A. Reivindicacion 2: La composicion de acuerdo con la reivindicacion 1, caracterizada porque la construccion de ADN comprende además un fragmento de una secuencia de ADN que codifica un fragmento de la proteína 2B unida a una secuencia de ADN que codifica a la proteasa 3C unida a un fragmento de la secuencia de ADN que codifica a un fragmento de la proteína 3D. Reivindicacion 4: La composicion de acuerdo con la reivindicacion 3, caracterizada porque dicha vacuna es seleccionadas del conjunto comprendido por vacunas parenterales, no-parenterales y comestibles. Reivindicacion 8: La composicion de acuerdo con la reivindicacion 7, caracterizada porque la planta transgénica es una planta de alfalfa. Reivindicacion 9: La composicion de acuerdo con la reivindicacion 1, caracterizada porque comprende al menos un adyuvante y/o excipiente farmacéuticamente aceptable.Claim 1: A composition for immunizing mammals against the foot and mouth disease virus, characterized in that it comprises at least one transgenic plant or a part of a transgenic plant that expresses empty capsids of the foot and mouth disease virus, wherein said transgenic plant or part thereof. It comprises in its genome a DNA construct comprising at least one DNA sequence encoding the precursor polyprotein P1 linked to a DNA sequence encoding the autocatalytic protease 2A. Claim 2: The composition according to claim 1, characterized in that the DNA construct further comprises a fragment of a DNA sequence encoding a fragment of the 2B protein linked to a DNA sequence encoding the 3C protease bound to a DNA sequence fragment that encodes a 3D protein fragment. Claim 4: The composition according to claim 3, characterized in that said vaccine is selected from the set comprising parenteral, non-parenteral and edible vaccines. Claim 8: The composition according to claim 7, characterized in that the transgenic plant is an alfalfa plant. Claim 9: The composition according to claim 1, characterized in that it comprises at least one pharmaceutically acceptable adjuvant and / or excipient.

ARP100103213 2010-09-01 2010-09-01 COMPOSITION TO IMMUNIZE MAMMALS AGAINST THE AFTOSA VIRUS AR078257A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ARP100103213 AR078257A2 (en) 2010-09-01 2010-09-01 COMPOSITION TO IMMUNIZE MAMMALS AGAINST THE AFTOSA VIRUS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ARP100103213 AR078257A2 (en) 2010-09-01 2010-09-01 COMPOSITION TO IMMUNIZE MAMMALS AGAINST THE AFTOSA VIRUS

Publications (1)

Publication Number Publication Date
AR078257A2 true AR078257A2 (en) 2011-10-26

Family

ID=45116469

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP100103213 AR078257A2 (en) 2010-09-01 2010-09-01 COMPOSITION TO IMMUNIZE MAMMALS AGAINST THE AFTOSA VIRUS

Country Status (1)

Country Link
AR (1) AR078257A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014036645A1 (en) 2012-09-05 2014-03-13 Medicago Inc. Picornavirus-like particle production in plants

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014036645A1 (en) 2012-09-05 2014-03-13 Medicago Inc. Picornavirus-like particle production in plants

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