AR075029A1 - METHOD TO PRODUCE A PROTEIN OR A PHYSIOLOGICALLY ACTIVE PEPTIDE USING AN IMMUNOGLOBULIN FRAGMENT - Google Patents
METHOD TO PRODUCE A PROTEIN OR A PHYSIOLOGICALLY ACTIVE PEPTIDE USING AN IMMUNOGLOBULIN FRAGMENTInfo
- Publication number
- AR075029A1 AR075029A1 ARP100100113A AR075029A1 AR 075029 A1 AR075029 A1 AR 075029A1 AR P100100113 A ARP100100113 A AR P100100113A AR 075029 A1 AR075029 A1 AR 075029A1
- Authority
- AR
- Argentina
- Prior art keywords
- protein
- physiologically active
- produce
- immunoglobulin fragment
- active peptide
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108010021625 Immunoglobulin Fragments Proteins 0.000 title abstract 2
- 102000008394 Immunoglobulin Fragments Human genes 0.000 title abstract 2
- 108020001507 fusion proteins Proteins 0.000 abstract 3
- 102000037865 fusion proteins Human genes 0.000 abstract 3
- 239000013604 expression vector Substances 0.000 abstract 2
- 244000005700 microbiome Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
Método para producir en masa una proteína o un péptido fisiologicamente activo usando una proteína de fusion compuesta de la proteína o del péptido fisiologicamente activo y un fragmento de inmunoglobulina. También se provee dicha proteína de fusion, un ADN que codifica la proteína de fusion, un vector de expresion que comprende el ADN, y un microorganismo transformado con el vector de expresion.Method for mass producing a physiologically active protein or peptide using a fusion protein composed of the physiologically active protein or peptide and an immunoglobulin fragment. Said fusion protein is also provided, a DNA encoding the fusion protein, an expression vector comprising the DNA, and a microorganism transformed with the expression vector.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20090004234 | 2009-01-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR075029A1 true AR075029A1 (en) | 2011-03-02 |
Family
ID=42340231
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP100100113 AR075029A1 (en) | 2009-01-19 | 2010-01-19 | METHOD TO PRODUCE A PROTEIN OR A PHYSIOLOGICALLY ACTIVE PEPTIDE USING AN IMMUNOGLOBULIN FRAGMENT |
Country Status (4)
| Country | Link |
|---|---|
| KR (1) | KR20100084996A (en) |
| AR (1) | AR075029A1 (en) |
| TW (1) | TW201031752A (en) |
| WO (1) | WO2010082804A2 (en) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL2348114T3 (en) | 2004-04-21 | 2019-08-30 | Alexion Pharmaceuticals, Inc. | Bone delivery conjugates and method of using same to target proteins to bone |
| EP2658979B1 (en) | 2010-12-27 | 2018-02-14 | Alexion Pharmaceuticals, Inc. | Compositions comprising natriuretic peptides and methods of use thereof |
| US10052366B2 (en) | 2012-05-21 | 2018-08-21 | Alexion Pharmaceuticsl, Inc. | Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof |
| US10822596B2 (en) | 2014-07-11 | 2020-11-03 | Alexion Pharmaceuticals, Inc. | Compositions and methods for treating craniosynostosis |
| MX389350B (en) | 2014-12-05 | 2025-03-19 | Alexion Pharma Inc | RECOMBINANT ALKALINE PHOSPHATASES AND THEIR USES FOR THE TREATMENT OF SEIZURES. |
| US10603361B2 (en) | 2015-01-28 | 2020-03-31 | Alexion Pharmaceuticals, Inc. | Methods of treating a subject with an alkaline phosphatase deficiency |
| KR102644116B1 (en) | 2015-08-17 | 2024-03-05 | 알렉시온 파마슈티칼스, 인코포레이티드 | Preparation of alkaline phosphatase |
| WO2017058822A1 (en) | 2015-09-28 | 2017-04-06 | Alexion Pharmaceuticals, Inc. | Identifying effective dosage regimens for tissue non-specific alkaline phosphatase (tnsalp)-enzyme replacement therapy of hypophosphatasia |
| JP2018533571A (en) | 2015-10-30 | 2018-11-15 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | Methods for treating cranial suture early healing disease in a patient |
| WO2017155569A1 (en) | 2016-03-08 | 2017-09-14 | Alexion Pharmaceuticals, Inc. | Methods for treating hypophosphatasia in children |
| EP3436020A4 (en) | 2016-04-01 | 2019-12-25 | Alexion Pharmaceuticals, Inc. | METHODS OF TREATING HYPOPHOSPHATASIA IN ADOLESCENTS AND ADULTS |
| CA3019726A1 (en) | 2016-04-01 | 2017-10-05 | Alexion Pharmaceuticals, Inc. | Treating muscle weakness with alkaline phosphatases |
| EP3464573A4 (en) | 2016-06-06 | 2020-02-19 | Alexion Pharmaceuticals, Inc. | IMPACT OF METAL ON THE PRODUCTION OF ALKALINE PHOSPHATASES |
| WO2018035420A1 (en) | 2016-08-18 | 2018-02-22 | Alexion Pharmaceuticals, Inc. | Methods for treating tracheobronchomalacia |
| JP2020512363A (en) | 2017-03-31 | 2020-04-23 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | Methods for treating hypophosphatasia (HPP) in adults and adolescents |
| US11913039B2 (en) | 2018-03-30 | 2024-02-27 | Alexion Pharmaceuticals, Inc. | Method for producing recombinant alkaline phosphatase |
| US12268733B2 (en) | 2018-08-10 | 2025-04-08 | Alexion Pharmaceuticals, Inc. | Methods of treating neurofibromatosis type 1 and related conditions with alkaline phosphatase |
| WO2020060202A1 (en) * | 2018-09-18 | 2020-03-26 | 한국생산기술연구원 | Expression cassette for preparing thymulin or argireline, and use thereof |
| KR102124035B1 (en) * | 2018-09-18 | 2020-06-19 | 한국생산기술연구원 | A expression cassette for preparation of thymulin and use thereof |
| CN111208243B (en) * | 2018-11-21 | 2022-05-17 | 中国科学院大连化学物理研究所 | Anion exchange chromatographic column-based SUMO peptide fragment enrichment method |
| JP2023504208A (en) | 2019-12-09 | 2023-02-01 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | Alkaline phosphatase polypeptides and methods of use thereof |
| US12083169B2 (en) | 2021-02-12 | 2024-09-10 | Alexion Pharmaceuticals, Inc. | Alkaline phosphatase polypeptides and methods of use thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5196321A (en) * | 1986-10-02 | 1993-03-23 | Massachusetts Institute Of Technology | Methods for in vitro cleavage of ubiquitin fusion proteins |
| US5225538A (en) * | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
| US5349053A (en) * | 1990-06-01 | 1994-09-20 | Protein Design Labs, Inc. | Chimeric ligand/immunoglobulin molecules and their uses |
| US6900292B2 (en) * | 2001-08-17 | 2005-05-31 | Lee-Hwei K. Sun | Fc fusion proteins of human erythropoietin with increased biological activities |
| JP4762904B2 (en) * | 2003-11-13 | 2011-08-31 | ハンミ ホールディングス カンパニー リミテッド | Mass production method of immunoglobulin constant region |
-
2010
- 2010-01-19 WO PCT/KR2010/000342 patent/WO2010082804A2/en not_active Ceased
- 2010-01-19 TW TW99101345A patent/TW201031752A/en unknown
- 2010-01-19 AR ARP100100113 patent/AR075029A1/en not_active Application Discontinuation
- 2010-01-19 KR KR1020100004639A patent/KR20100084996A/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010082804A3 (en) | 2010-11-25 |
| TW201031752A (en) | 2010-09-01 |
| WO2010082804A2 (en) | 2010-07-22 |
| KR20100084996A (en) | 2010-07-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |