AR060869A1 - SOLID PHARMACEUTICAL COMPOSITION OF GABAPENTINA - Google Patents
SOLID PHARMACEUTICAL COMPOSITION OF GABAPENTINAInfo
- Publication number
- AR060869A1 AR060869A1 ARP070101988A ARP070101988A AR060869A1 AR 060869 A1 AR060869 A1 AR 060869A1 AR P070101988 A ARP070101988 A AR P070101988A AR P070101988 A ARP070101988 A AR P070101988A AR 060869 A1 AR060869 A1 AR 060869A1
- Authority
- AR
- Argentina
- Prior art keywords
- gabapentin
- refers
- pharmaceutical composition
- solid pharmaceutical
- composition
- Prior art date
Links
- UGJMXCAKCUNAIE-UHFFFAOYSA-N Gabapentin Chemical group OC(=O)CC1(CN)CCCCC1 UGJMXCAKCUNAIE-UHFFFAOYSA-N 0.000 title abstract 7
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title abstract 2
- 229960002870 gabapentin Drugs 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000000080 wetting agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente se refiere a una composicion farmacéutica solida que comprende gabapentina, un compuesto hidrofobico, un agente humectante, y un agente aglutinante. Dicha combinacion de excipientes confiere una buena estabilidad y buena biodisponibilidad del principio activo. También se refiere al uso de dicha composicion para la preparacion de formas farmacéuticas de gabapentina para su administracion por vía oral. Se refiere también a comprimidos preparados con dicha composicion que presentan unas propiedades apropiadas en cuanto a la solubilidad y a la biodisponibilidad de la gabapentina.This refers to a solid pharmaceutical composition comprising gabapentin, a hydrophobic compound, a wetting agent, and a binding agent. Said combination of excipients confers good stability and good bioavailability of the active substance. It also refers to the use of said composition for the preparation of pharmaceutical forms of gabapentin for oral administration. It also refers to tablets prepared with said composition that have appropriate properties in terms of solubility and bioavailability of gabapentin.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200601164A ES2288117B1 (en) | 2006-05-08 | 2006-05-08 | SOLID PHARMACEUTICAL COMPOSITION OF GABAPENTINA. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR060869A1 true AR060869A1 (en) | 2008-07-16 |
Family
ID=38668112
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP070101988A AR060869A1 (en) | 2006-05-08 | 2007-05-08 | SOLID PHARMACEUTICAL COMPOSITION OF GABAPENTINA |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP2020993A2 (en) |
| AR (1) | AR060869A1 (en) |
| ES (1) | ES2288117B1 (en) |
| WO (1) | WO2007128495A2 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102009012788A1 (en) * | 2009-03-13 | 2010-09-30 | J. Rettenmaier & Söhne Gmbh + Co. Kg | Compressible tablet material with oily agent, tablet and method and apparatus for their preparation |
| PT3277270T (en) | 2015-04-01 | 2021-12-07 | Akebia Therapeutics Inc | COMPOSITIONS AND METHODS OF TREATMENT OF ANEMIA |
| US10342886B2 (en) | 2016-01-26 | 2019-07-09 | S.C. Johnson & Son, Inc. | Extruded wax melt and method of producing same |
| US10010638B2 (en) | 2016-06-14 | 2018-07-03 | S. C. Johnson & Son, Inc. | Wax melt with filler |
| WO2019036713A1 (en) | 2017-08-18 | 2019-02-21 | Abbvie Inc. | Solid pharmaceutical formulations for treating endometriosis, uterine fibroids, polycystic ovary syndrome and adenomyosis |
| AU2018317472A1 (en) | 2017-08-18 | 2020-03-05 | Abbvie Inc. | Pharmaceutical formulations for treating endometriosis, uterine fibroids, polycystic ovary syndrome or adenomyosis |
| GB2625579A (en) * | 2022-12-21 | 2024-06-26 | Novumgen Ltd | An orally disintegrating tablet containing gabapentin or pharmaceutically acceptable salts thereof and the process of preparing the same |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000076478A1 (en) * | 1999-06-14 | 2000-12-21 | Cosmo S.P.A. | Controlled release and taste masking oral pharmaceutical compositions |
| US7056951B2 (en) * | 2000-09-26 | 2006-06-06 | Mutual Pharmaceutical Co., Inc. | Stable solid dosage forms of amino acids and processes for producing same |
| ITMI20011337A1 (en) * | 2001-06-26 | 2002-12-26 | Farmatron Ltd | ORAL PHARMACEUTICAL COMPOSITIONS WITH MODIFIED RELEASE OF THE ACTIVE SUBSTANCE |
| EP1455751A1 (en) * | 2001-12-20 | 2004-09-15 | Pharmacia Corporation | Zero-order sustained released dosage forms and method of making the same |
| WO2003103634A1 (en) * | 2002-06-07 | 2003-12-18 | Ranbaxy Laboratories Limited | Sustained release oral dosage forms of gabapentin |
| US20060039968A1 (en) * | 2002-10-08 | 2006-02-23 | Ramalingam Manikandan | Gabapentin tablets and method for their preparation |
| GB0408308D0 (en) * | 2004-04-14 | 2004-05-19 | Vectura Ltd | Pharmaceutical compositions |
-
2006
- 2006-05-08 ES ES200601164A patent/ES2288117B1/en not_active Expired - Fee Related
-
2007
- 2007-05-03 EP EP07785797A patent/EP2020993A2/en not_active Withdrawn
- 2007-05-03 WO PCT/EP2007/003914 patent/WO2007128495A2/en not_active Ceased
- 2007-05-08 AR ARP070101988A patent/AR060869A1/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2288117A1 (en) | 2007-12-16 |
| WO2007128495A3 (en) | 2008-05-02 |
| WO2007128495A2 (en) | 2007-11-15 |
| ES2288117B1 (en) | 2008-12-01 |
| EP2020993A2 (en) | 2009-02-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |