AR069025A1 - Un extracto de planta estandarizado, proceso para obtenerlo y usos del mismo, aislado o en una composicion farmaceutica, para prevencion, control o tratamiento de afecciones dolorosas, inflamatorias y febriles - Google Patents
Un extracto de planta estandarizado, proceso para obtenerlo y usos del mismo, aislado o en una composicion farmaceutica, para prevencion, control o tratamiento de afecciones dolorosas, inflamatorias y febrilesInfo
- Publication number
- AR069025A1 AR069025A1 ARP080104646A ARP080104646A AR069025A1 AR 069025 A1 AR069025 A1 AR 069025A1 AR P080104646 A ARP080104646 A AR P080104646A AR P080104646 A ARP080104646 A AR P080104646A AR 069025 A1 AR069025 A1 AR 069025A1
- Authority
- AR
- Argentina
- Prior art keywords
- extract
- plant
- standardized
- pharmaceutical composition
- inflammatory
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 4
- 230000002757 inflammatory effect Effects 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 239000000419 plant extract Substances 0.000 title 1
- 241000196324 Embryophyta Species 0.000 abstract 6
- 241000545417 Aleurites Species 0.000 abstract 4
- 238000001035 drying Methods 0.000 abstract 2
- 238000000605 extraction Methods 0.000 abstract 2
- 239000003550 marker Substances 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 206010037660 Pyrexia Diseases 0.000 abstract 1
- OZWDYLLMBFLSNH-UHFFFAOYSA-N Swertisin Natural products COc1cc2OC(=CC(=O)c2c(O)c1OC3OC(CO)C(O)C(O)C3O)c4cccc(O)c4 OZWDYLLMBFLSNH-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000003502 anti-nociceptive effect Effects 0.000 abstract 1
- 230000001754 anti-pyretic effect Effects 0.000 abstract 1
- -1 biological molecules Substances 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 238000003306 harvesting Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000009928 pasteurization Methods 0.000 abstract 1
- 238000004451 qualitative analysis Methods 0.000 abstract 1
- 238000004445 quantitative analysis Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- ABRULANJVVJLFI-DGHBBABESA-N swertisin Chemical compound COC1=CC=2OC(C=3C=CC(O)=CC=3)=CC(=O)C=2C(O)=C1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O ABRULANJVVJLFI-DGHBBABESA-N 0.000 abstract 1
- 229940088594 vitamin Drugs 0.000 abstract 1
- 229930003231 vitamin Natural products 0.000 abstract 1
- 235000013343 vitamin Nutrition 0.000 abstract 1
- 239000011782 vitamin Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/06—Benzopyran radicals
- C07H17/065—Benzo[b]pyrans
- C07H17/07—Benzo[b]pyran-4-ones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Dispersion Chemistry (AREA)
- Alternative & Traditional Medicine (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Proceso de obtención de un extracto estandarizado a partir de por lo menos una parte de una planta del género Aleurites con propiedades antinociceptivas, antiinflamatorias y antipiréticas, a partir de una planta del género Aleurites. Composición farmacéutica, que comprende como ingrediente activo una cantidad farmacéuticamente eficaz de un extracto estandarizado de por lo menos una parte de una planta del género Aleurites. Por último, la presente trata de un método de tratamiento y uso de dicho extracto, aislado o en una composición farmacéutica, para prevención, control o tratamiento de afecciones dolorosas, inflamatorias y febriles. Reivindicación 1: Proceso de obtención de un extracto estandarizado caracterizado porque emplea por lo menos una parte de una planta del género Aleurites, y comprende las etapas de: (i) recolección, secado y subdivisión del material vegetal; (ii) pre-extracción; (iii) extracción con solvente extractor; (iv) filtración del extracto; (v) concentración del extracto; (vi) pasteurización; (vii) secado; y (viii) análisis cualitativo y cuantitativo (estandarización) del extracto; siendo dicho extracto estandarizado distinguido por el marcador 2-O-ramnosil-swertisina. Reivindicación 20: Extracto estandarizado caracterizado porque es obtenido de acuerdo con las reivindicaciones 1 a 19. Reivindicación 21: Extracto de acuerdo con la reivindicación 20, caracterizado porque contiene por lo menos un principio activo seleccionado del grupo que consiste en a-amirina, b-amirina, a-amirinona, b-amirinona, swertisina, siendo dicho extracto estandarizado en relación con su marcador 2-O-ramnosil-swertisina. Reivindicación 33: Composición farmacéutica de acuerdo con la reivindicación 30, caracterizada porque, adicionalmente, contiene por lo menos una sustancia farmacológicamente activa seleccionada del grupo que consiste en sustancias sintéticas, semi-sintéticas, moléculas biológicas, vitaminas y otras sustancias derivadas de origen vegetal.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BRPI0703947 | 2007-10-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR069025A1 true AR069025A1 (es) | 2009-12-23 |
Family
ID=40580121
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080104646A AR069025A1 (es) | 2007-10-26 | 2008-10-24 | Un extracto de planta estandarizado, proceso para obtenerlo y usos del mismo, aislado o en una composicion farmaceutica, para prevencion, control o tratamiento de afecciones dolorosas, inflamatorias y febriles |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US8404283B2 (es) |
| EP (1) | EP2217257A4 (es) |
| AR (1) | AR069025A1 (es) |
| CA (1) | CA2703652A1 (es) |
| CL (1) | CL2008003154A1 (es) |
| CO (1) | CO6280404A2 (es) |
| MX (1) | MX2010004513A (es) |
| WO (1) | WO2009052600A2 (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX344885B (es) * | 2008-11-10 | 2017-01-10 | Psicofarma S A De C V | Proceso para la obtencion de una composicion de rosuvastatina calcica y producto obtenido. |
| AU2010316120B2 (en) * | 2009-11-03 | 2013-11-21 | Korea Research Institute Of Bioscience And Biotechnology | Antiviral composition containing an Aleurites fordii or Daphne kiusiana extract or a fraction thereof as an active ingredient |
| FR3013594B1 (fr) * | 2013-11-25 | 2017-11-10 | Basf Beauty Care Solutions France Sas | Utilisation cosmetique ou dermatologique d'un extrait d'aleurites moluccana |
| CN110483297A (zh) * | 2018-05-15 | 2019-11-22 | 复旦大学 | 1,5-二烯型巴豆烷二萜及其在制备抗艾滋病毒药物中的用途 |
| CN109289815B (zh) * | 2018-10-24 | 2021-05-21 | 温州医科大学 | 一种磁性泡腾片、磁性泡腾片辅助分散固相微萃取方法、重金属检测方法及应用 |
-
2008
- 2008-10-24 AR ARP080104646A patent/AR069025A1/es unknown
- 2008-10-24 US US12/739,921 patent/US8404283B2/en not_active Expired - Fee Related
- 2008-10-24 MX MX2010004513A patent/MX2010004513A/es active IP Right Grant
- 2008-10-24 CL CL2008003154A patent/CL2008003154A1/es unknown
- 2008-10-24 EP EP08841818.1A patent/EP2217257A4/en not_active Ceased
- 2008-10-24 CA CA2703652A patent/CA2703652A1/en not_active Abandoned
- 2008-10-24 WO PCT/BR2008/000319 patent/WO2009052600A2/en not_active Ceased
-
2010
- 2010-05-24 CO CO10061904A patent/CO6280404A2/es not_active Application Discontinuation
-
2013
- 2013-02-28 US US13/780,875 patent/US20130243860A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009052600A2 (en) | 2009-04-30 |
| MX2010004513A (es) | 2010-08-02 |
| CA2703652A1 (en) | 2009-04-30 |
| CL2008003154A1 (es) | 2009-10-23 |
| CO6280404A2 (es) | 2011-05-20 |
| US8404283B2 (en) | 2013-03-26 |
| EP2217257A4 (en) | 2013-06-12 |
| EP2217257A2 (en) | 2010-08-18 |
| US20130243860A1 (en) | 2013-09-19 |
| US20100303907A1 (en) | 2010-12-02 |
| WO2009052600A3 (en) | 2009-12-03 |
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| FB | Suspension of granting procedure |