AR043070A1 - Sistema monolitico que contiene una o mas drogas, formado por tres capas con diferentes mecanismos de liberacion - Google Patents
Sistema monolitico que contiene una o mas drogas, formado por tres capas con diferentes mecanismos de liberacionInfo
- Publication number
- AR043070A1 AR043070A1 ARP980104937A ARP980104937A AR043070A1 AR 043070 A1 AR043070 A1 AR 043070A1 AR P980104937 A ARP980104937 A AR P980104937A AR P980104937 A ARP980104937 A AR P980104937A AR 043070 A1 AR043070 A1 AR 043070A1
- Authority
- AR
- Argentina
- Prior art keywords
- drugs
- monolitical
- liberation
- layers
- system containing
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 229940079593 drug Drugs 0.000 title abstract 2
- 238000013270 controlled release Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000008961 swelling Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Abstract
Se describe un sistema monolítico de liberación controlada para la administración por vía oral, que comprende una capa disgregante, una capa erosionable y a capa de hinchamiento, de las cuales dos son externas y una es intermedia, donde cada capa contiene una o más drogas. También se describen las propiedades de liberación y el método de su preparación.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT97MI002254A IT1295271B1 (it) | 1997-10-03 | 1997-10-03 | Monolita contenente uno o piu'farmaci costituito da tre strati a meccanismo di rilascio differenziato |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR043070A1 true AR043070A1 (es) | 2005-07-20 |
Family
ID=11377984
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP980104937A AR043070A1 (es) | 1997-10-03 | 1998-10-02 | Sistema monolitico que contiene una o mas drogas, formado por tres capas con diferentes mecanismos de liberacion |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1019029B1 (es) |
| AR (1) | AR043070A1 (es) |
| AT (1) | ATE248590T1 (es) |
| AU (1) | AU9629198A (es) |
| BR (1) | BR9815248A (es) |
| CZ (1) | CZ298851B6 (es) |
| DE (1) | DE69817848T2 (es) |
| ES (1) | ES2205558T3 (es) |
| HU (1) | HU225692B1 (es) |
| IT (1) | IT1295271B1 (es) |
| NO (1) | NO20001709L (es) |
| SK (1) | SK284552B6 (es) |
| WO (1) | WO1999017745A1 (es) |
| ZA (1) | ZA989010B (es) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002340470A1 (en) | 2001-11-13 | 2003-05-26 | Teva Pharmaceutical Industries, Ltd. | L-dopa ethyl ester salts and uses thereof |
| US20030224045A1 (en) * | 2002-05-29 | 2003-12-04 | Chien-Hsuan Han | Combination immediate release sustained release levodopa/carbidopa dosage forms |
| US7094427B2 (en) * | 2002-05-29 | 2006-08-22 | Impax Laboratories, Inc. | Combination immediate release controlled release levodopa/carbidopa dosage forms |
| US20080299204A1 (en) * | 2005-06-23 | 2008-12-04 | Spherics, Inc. | Dosage forms for movement disorder treatment |
| ATE489079T1 (de) * | 2005-12-29 | 2010-12-15 | Osmotica Kereskedelmi Es Szolgaltata Kft | Mehrschichtige tablette mit dreifacher freisetzungskombination |
| CN102202656A (zh) | 2008-08-15 | 2011-09-28 | 蒂宝制药公司 | 治疗和预防cns障碍的胃滞留药用组合物 |
| JP5905872B2 (ja) * | 2010-04-07 | 2016-04-20 | ルピン・リミテッド | タペンタドールの制御放出医薬組成物 |
| EP2508174A1 (en) | 2011-04-06 | 2012-10-10 | Ljiljana Sovic Brkicic | Pharmaceutical composition |
| US20130143867A1 (en) | 2011-12-02 | 2013-06-06 | Sychroneuron Inc. | Acamprosate formulations, methods of using the same, and combinations comprising the same |
| ITMI20121263A1 (it) * | 2012-07-19 | 2014-01-20 | Recordati Ind Chimica E Farma Ceutica S P A | Forma farmaceutica multistrato |
| CN105431144A (zh) | 2013-06-05 | 2016-03-23 | 思康脑侒股份有限公司 | 阿坎酸制剂、使用阿坎酸制剂的方法以及包含阿坎酸制剂的组合 |
| US10987313B2 (en) | 2013-10-07 | 2021-04-27 | Impax Laboratories, Llc | Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof |
| CA2926082C (en) * | 2013-10-07 | 2022-06-14 | Impax Laboratories, Inc. | Muco-adhesive, controlled release formulations of levodopa and/or esters of levodopa and uses thereof |
| GB201506755D0 (en) | 2015-04-21 | 2015-06-03 | Reckitt Benckiser Llc | Novel pharmaceutical formulation |
| US9808478B2 (en) * | 2015-04-17 | 2017-11-07 | Steven Loyd | Control release of fat soluble antioxidants from an oral formulation and method |
| US11278506B2 (en) | 2015-10-09 | 2022-03-22 | Rb Health (Us) Llc | Pharmaceutical formulation |
| US11986449B2 (en) | 2020-12-22 | 2024-05-21 | Amneal Pharmaceuticals Llc | Levodopa dosing regimen |
| WO2022140448A1 (en) | 2020-12-22 | 2022-06-30 | Amneal Pharmaceuticals Llc | Levodopa dosing regimen |
| CN117599009A (zh) * | 2023-11-10 | 2024-02-27 | 长沙晶易医药科技股份有限公司 | 一种卡左双多巴三层片及其制备方法 |
| CN118831063A (zh) * | 2024-07-18 | 2024-10-25 | 泰州越洋医药开发有限公司 | 一种三层片制剂及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1255522B (it) * | 1992-09-24 | 1995-11-09 | Ubaldo Conte | Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita' |
| IT1256393B (it) * | 1992-11-17 | 1995-12-04 | Inverni Della Beffa Spa | Forme matriciali multistrato per il rilascio controllato di principi attivi |
| IT1264696B1 (it) * | 1993-07-09 | 1996-10-04 | Applied Pharma Res | Forme farmaceutiche destinate alla somministrazione orale in grado di rilasciare sostanze attive a velocita' controllata e differenziata |
| IT1282576B1 (it) * | 1996-02-06 | 1998-03-31 | Jagotec Ag | Compressa farmaceutica atta a cedere la sostanza attiva in tempi successivi e predeterminabili |
-
1997
- 1997-10-03 IT IT97MI002254A patent/IT1295271B1/it active IP Right Grant
-
1998
- 1998-10-01 EP EP98950099A patent/EP1019029B1/en not_active Expired - Lifetime
- 1998-10-01 SK SK482-2000A patent/SK284552B6/sk unknown
- 1998-10-01 DE DE69817848T patent/DE69817848T2/de not_active Expired - Lifetime
- 1998-10-01 CZ CZ20001200A patent/CZ298851B6/cs not_active IP Right Cessation
- 1998-10-01 AU AU96291/98A patent/AU9629198A/en not_active Abandoned
- 1998-10-01 HU HU0004015A patent/HU225692B1/hu not_active IP Right Cessation
- 1998-10-01 BR BR9815248-3A patent/BR9815248A/pt not_active Application Discontinuation
- 1998-10-01 WO PCT/EP1998/006228 patent/WO1999017745A1/en not_active Ceased
- 1998-10-01 AT AT98950099T patent/ATE248590T1/de not_active IP Right Cessation
- 1998-10-01 ES ES98950099T patent/ES2205558T3/es not_active Expired - Lifetime
- 1998-10-02 ZA ZA989010A patent/ZA989010B/xx unknown
- 1998-10-02 AR ARP980104937A patent/AR043070A1/es not_active Application Discontinuation
-
2000
- 2000-04-03 NO NO20001709A patent/NO20001709L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1019029A1 (en) | 2000-07-19 |
| SK284552B6 (sk) | 2005-06-02 |
| ZA989010B (en) | 1999-04-12 |
| NO20001709D0 (no) | 2000-04-03 |
| EP1019029B1 (en) | 2003-09-03 |
| DE69817848D1 (de) | 2003-10-09 |
| AU9629198A (en) | 1999-04-27 |
| ITMI972254A1 (it) | 1999-04-03 |
| NO20001709L (no) | 2000-06-05 |
| IT1295271B1 (it) | 1999-05-04 |
| HUP0004015A2 (hu) | 2001-08-28 |
| SK4822000A3 (en) | 2000-09-12 |
| CZ298851B6 (cs) | 2008-02-27 |
| ATE248590T1 (de) | 2003-09-15 |
| BR9815248A (pt) | 2000-11-21 |
| DE69817848T2 (de) | 2005-04-07 |
| HU225692B1 (en) | 2007-06-28 |
| WO1999017745A1 (en) | 1999-04-15 |
| ES2205558T3 (es) | 2004-05-01 |
| HUP0004015A3 (en) | 2006-06-28 |
| CZ20001200A3 (cs) | 2000-09-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |