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AR047372A1 - Anticuerpos contra madcam - Google Patents

Anticuerpos contra madcam

Info

Publication number
AR047372A1
AR047372A1 ARP050100053A ARP050100053A AR047372A1 AR 047372 A1 AR047372 A1 AR 047372A1 AR P050100053 A ARP050100053 A AR P050100053A AR P050100053 A ARP050100053 A AR P050100053A AR 047372 A1 AR047372 A1 AR 047372A1
Authority
AR
Argentina
Prior art keywords
antibodies
madcam
refers
human
human anti
Prior art date
Application number
ARP050100053A
Other languages
English (en)
Inventor
Nicholas Pullen
Elizabeth Molloy
Sirid-Aimee Kellermann
Larry Green
Mary Haak Frendscho
Original Assignee
Pfizer
Abgenix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34794356&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR047372(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer, Abgenix Inc filed Critical Pfizer
Publication of AR047372A1 publication Critical patent/AR047372A1/es

Links

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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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Abstract

La presente se refiere a anticuerpos que incluyen anticuerpos humanos y porciones que ligan antígeno de los mismos que se ligan específicamente a MAdCAM, preferentemente a MAdCAM humano y que funcionan para inhibir MAdCAM. También se refiere a anticuerpos anti-MAdCAM humanos y porciones que ligan antígeno de los mismos. También se refiere a anticuerpos que son quiméricos, biespecíficos, derivatizados, anticuerpos de cadena simple o porciones de proteínas de fusion. También se refiere a inmunoglobulinas aisladas de cadena pesada y liviana derivadas de anticuerpos anti-MAdCAM humanos y a moléculas de ácido nucleico que codifican tales inmunoglobulinas. También se refiere a métodos para fabricar anticuerpos anti-MAdCAM humanos, a composiciones que comprenden estos anticuerpos y a métodos para usar los anticuerpos y composiciones para diagnostico y tratamiento. Se proveen métodos de terapia con genes que usan moléculas de ácido nucleico que codifican la cadena pesada y/o liviana de moléculas de inmunoglobulina que comprenden los anticuerpos anti-MAdCAM humanos. También se refiere a líneas celulares y de hibridomas y a animales o plantas transgénicos que comprenden dichas moléculas de ácido nucleico. Reivindicacion 1: Un anticuerpo monoclonal humano o una porcion que liga antígeno del mismo que se liga específicamente a la molécula de adhesion celular de adresina mucosal (MAdCAM).
ARP050100053A 2004-01-09 2005-01-07 Anticuerpos contra madcam AR047372A1 (es)

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