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AR046076A1 - Procedimiento para obtener una poblacion homogenea de celulas precursoras de oligodendrocitos y poblacion obtenida - Google Patents

Procedimiento para obtener una poblacion homogenea de celulas precursoras de oligodendrocitos y poblacion obtenida

Info

Publication number
AR046076A1
AR046076A1 ARP040102543A ARP040102543A AR046076A1 AR 046076 A1 AR046076 A1 AR 046076A1 AR P040102543 A ARP040102543 A AR P040102543A AR P040102543 A ARP040102543 A AR P040102543A AR 046076 A1 AR046076 A1 AR 046076A1
Authority
AR
Argentina
Prior art keywords
precursor cells
population
oligodendrocyte precursor
obtaining
procedures
Prior art date
Application number
ARP040102543A
Other languages
English (en)
Inventor
Hiroshi Okazaki
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of AR046076A1 publication Critical patent/AR046076A1/es

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
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    • C12N5/0602—Vertebrate cells
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Abstract

Población fenotípicamente homogénea autorenovante de células precursoras de oligodendrocitos con estado de desarrollo sincronizado y procedimientos para obtener una población fenotípicamente homogénea autorenovante de células precursoras de oligodendrocitos. Otros procedimientos incluyen procedimientos para mantener y almacenar una población homogénea de células precursoras de oligodendrocitos durante períodos prolongados sin cambio en las características de las células y procedimientos para diferenciar células precursoras de oligodendrocitos. La población fenotípicamente homogénea autorenovante de células precursoras de oligodendrocitos o población homogénea de oligodendrocitos pueden ser útil para tratar a un paciente que tiene un desorden o condición del sistema nervioso central. Reivindicación 1: Procedimiento para obtener una población homogénea de células precursoras de oligodendrocitos que tienen un estado de desarrollo sincronizado, caracterizado porque comprende cultivar una población heterogénea de células precursoras de oligodendrocitos que tienen un estado de desarrollo no sincronizado, en un medio que comprende una cantidad de factor de crecimiento de fibroblasto (FGF) eficaz para inducir una etapa sincronizada de desarrollo y en donde dicho cultivo se lleva a cabo en ausencia sustancial de factor de crecimiento derivado de plaquetas (FCDP), obteniendo así dicha población homogénea de células precursoras de oligodendrocitos que tienen un estado de desarrollo sincronizado.
ARP040102543A 2003-07-18 2004-07-16 Procedimiento para obtener una poblacion homogenea de celulas precursoras de oligodendrocitos y poblacion obtenida AR046076A1 (es)

Applications Claiming Priority (1)

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US48793303P 2003-07-18 2003-07-18

Publications (1)

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AR046076A1 true AR046076A1 (es) 2005-11-23

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Country Link
US (1) US20060172415A1 (es)
EP (1) EP1646711A4 (es)
JP (1) JP2007530001A (es)
KR (1) KR20060037346A (es)
CN (1) CN1833021A (es)
AR (1) AR046076A1 (es)
AU (1) AU2004257000B2 (es)
BR (1) BRPI0412715A (es)
CA (1) CA2532216A1 (es)
MX (1) MXPA05014161A (es)
SG (1) SG144166A1 (es)
TW (1) TW200510537A (es)
WO (1) WO2005007797A2 (es)

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AU2004257000A1 (en) 2005-01-27
SG144166A1 (en) 2008-07-29
BRPI0412715A (pt) 2006-09-26
JP2007530001A (ja) 2007-11-01
EP1646711A4 (en) 2008-03-19
EP1646711A2 (en) 2006-04-19
WO2005007797A3 (en) 2006-05-11
CN1833021A (zh) 2006-09-13
TW200510537A (en) 2005-03-16
KR20060037346A (ko) 2006-05-03
AU2004257000B2 (en) 2011-07-21
US20060172415A1 (en) 2006-08-03
WO2005007797A2 (en) 2005-01-27
CA2532216A1 (en) 2005-01-27
MXPA05014161A (es) 2006-05-25

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