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AR033520A1 - (5r)-(metilamino) -5,6-dihidro-4h-imidazo[4,5,1-ij] quinolin-2(1h)-tiona - Google Patents

(5r)-(metilamino) -5,6-dihidro-4h-imidazo[4,5,1-ij] quinolin-2(1h)-tiona

Info

Publication number
AR033520A1
AR033520A1 ARP010101768A ARP010101768A AR033520A1 AR 033520 A1 AR033520 A1 AR 033520A1 AR P010101768 A ARP010101768 A AR P010101768A AR P010101768 A ARP010101768 A AR P010101768A AR 033520 A1 AR033520 A1 AR 033520A1
Authority
AR
Argentina
Prior art keywords
quinolin
imidazo
dihidro
tiona
methylamine
Prior art date
Application number
ARP010101768A
Other languages
English (en)
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of AR033520A1 publication Critical patent/AR033520A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

(5R)-5-(metilamino)-5,6-dihidro-4H-imidazo[4, 5,1-ij] quinolin-2(1H)-tiona, formula 1 y sales farmacéuticamente aceptables del mismo. El compuesto es de utilidad en el campo farmacéutico para el tratamiento de la enfermedad de Parkinson y diversas disfunciones sexuales.
ARP010101768A 2000-04-27 2001-04-16 (5r)-(metilamino) -5,6-dihidro-4h-imidazo[4,5,1-ij] quinolin-2(1h)-tiona AR033520A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19995400P 2000-04-27 2000-04-27
US23410100P 2000-09-21 2000-09-21

Publications (1)

Publication Number Publication Date
AR033520A1 true AR033520A1 (es) 2003-12-26

Family

ID=26895318

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010101768A AR033520A1 (es) 2000-04-27 2001-04-16 (5r)-(metilamino) -5,6-dihidro-4h-imidazo[4,5,1-ij] quinolin-2(1h)-tiona

Country Status (10)

Country Link
US (3) US20020137763A1 (es)
JP (1) JP2003531907A (es)
KR (1) KR20020093090A (es)
CN (1) CN1420886A (es)
AR (1) AR033520A1 (es)
AU (1) AU2001255225A1 (es)
BR (1) BR0110323A (es)
CA (1) CA2404936A1 (es)
PE (1) PE20011181A1 (es)
WO (1) WO2001083483A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR031152A1 (es) 2000-10-31 2003-09-10 Upjohn Co Tratamientos nuevos para el sindrome de piernas inquietas
MXPA05003513A (es) * 2002-10-04 2005-06-03 Pharmacia Corp Composiciones farmaceuticas para tratamiento de enfermedad de parkinson.
BRPI0613430A2 (pt) 2005-07-13 2011-01-11 Hoffmann La Roche compostos derivados de benzimidazol, uso dos mesmos, método para a preparação destes e composição farmacêutica
CN111349094B (zh) * 2020-04-23 2021-02-02 杭州师范大学 一种6H-咪唑[4,5,1-ij]并喹诺酮及其合成方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4688195A (en) * 1983-01-28 1987-08-18 Texas Instruments Incorporated Natural-language interface generating system
US5083268A (en) * 1986-10-15 1992-01-21 Texas Instruments Incorporated System and method for parsing natural language by unifying lexical features of words
US4935514A (en) * 1989-06-06 1990-06-19 Ethyl Corporation Thiation process
US5273975A (en) * 1989-06-09 1993-12-28 The Upjohn Company Heterocyclic amines having central nervous system activity
DK0480939T3 (da) * 1989-06-09 1995-07-10 Upjohn Co Heterocycliske aminer med virkning på centralnervesystemet
US5237975A (en) * 1992-10-27 1993-08-24 Ford Motor Company Returnless fuel delivery system
USRE40278E1 (en) * 1993-07-27 2008-04-29 Pharmacia & Upjohn Company Heterocyclic amines having central nervous system activity
US6455564B1 (en) * 1999-01-06 2002-09-24 Pharmacia & Upjohn Company Method of treating sexual disturbances
ATE312608T1 (de) * 2000-04-21 2005-12-15 Pharmacia & Upjohn Co Llc Cabergolin zur behandlung von fibromyalgie und chronic-fatigue-syndrom

Also Published As

Publication number Publication date
US20040266812A1 (en) 2004-12-30
AU2001255225A1 (en) 2001-11-12
BR0110323A (pt) 2003-01-07
KR20020093090A (ko) 2002-12-12
PE20011181A1 (es) 2001-11-15
US20040029909A1 (en) 2004-02-12
CN1420886A (zh) 2003-05-28
CA2404936A1 (en) 2001-11-08
US20020137763A1 (en) 2002-09-26
JP2003531907A (ja) 2003-10-28
WO2001083483A1 (en) 2001-11-08

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