AR031526A1 - Nuevas fenilpiperazinas, composiciones farmaceuticas que las contienen, metodos para preparar los compuestos y las composiciones y uso de los compuestos en la preparacion de un medicamento. - Google Patents
Nuevas fenilpiperazinas, composiciones farmaceuticas que las contienen, metodos para preparar los compuestos y las composiciones y uso de los compuestos en la preparacion de un medicamento.Info
- Publication number
- AR031526A1 AR031526A1 ARP000104326A ARP000104326A AR031526A1 AR 031526 A1 AR031526 A1 AR 031526A1 AR P000104326 A ARP000104326 A AR P000104326A AR P000104326 A ARP000104326 A AR P000104326A AR 031526 A1 AR031526 A1 AR 031526A1
- Authority
- AR
- Argentina
- Prior art keywords
- group
- formula
- compounds
- alkyl
- nitrogen
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Nuevos derivados de fenilpiperazinas con aplicacion farmacologica en el tratamiento de afecciones del sistema nervioso central de la formula (1) en donde: X es 1) un grupo de la formula (1') en donde S1 es hidrogeno o halogeno, S2 y S3 son independientemente hidrogeno, alquilo (C1-6), fenilo o bencilo, S4 representa dos átomos de hidrogeno o un grupo oxo, S5 es H o alquilo (C1-4), y Y es C, O o S, 2) un grupo de la formula (2) en donde S1 tiene el significado anterior y R es H, alquilo (C1-4), alcoxialquilo (C2-6), alquenilo (C2-4), alquinilo (C2-4), o 3) un grupo de la formula (3) en donde S1 tiene el significado anterior y Z es C, O o N, o 4) un grupo de la formula (4) en donde S1 tiene el significado anterior o 5) un grupo de la formula (5) en donde S1 tiene el significado anterior y A es O o N, ligado al anillo de piperazina en las posiciones 5 u 8, 6) un grupo de la formula (6) en donde S1 tiene el significado anterior y S6 y S7 representan átomos de hidrogeno o un grupo oxo, o 7) un grupo de la formula (7) en donde una de las líneas punteadas puede representar un enlace doble, S1 tiene el significado anterior y P=T=Q=nitrogeno o P=T=nitrogeno y Q=C o P=Q=nitrogeno y T=C o C-CH3 o P=nitrogeno, y T y Q son carbono o P=nitrogeno, T es carbono y Q es azufre; m tiene el valor de 2 a 6; n tiene el valor de 0û2 ; R5 y R6 son independientemente H o alquilo (C1-3); o R5 + R6 representan un grupo û(CH2)p- en donde p tiene el valor de 3 û 5, y R7 es alquilo (C1-3), alcoxi (C1-3), halogeno o ciano; o R6 + R7 (R7 en posicion 7 del grupo indol) representan un grupo û(CH2)q en donde q tiene el valor de 2 û4, y sales de los mismos. Un método para preparar los compuestos de formula (1), una composicion farmacéutica que los contiene y métodos para prepararlas, así como el uso de los compuestos de formula (1) en la preparacion de medicamentos para tratar desordenes del sistema nervioso central.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL1012888 | 1999-08-23 | ||
| EP99202710 | 1999-08-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR031526A1 true AR031526A1 (es) | 2003-09-24 |
Family
ID=26153354
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP000104326A AR031526A1 (es) | 1999-08-23 | 2000-08-22 | Nuevas fenilpiperazinas, composiciones farmaceuticas que las contienen, metodos para preparar los compuestos y las composiciones y uso de los compuestos en la preparacion de un medicamento. |
Country Status (29)
| Country | Link |
|---|---|
| US (3) | US7067513B1 (es) |
| EP (1) | EP1212320B1 (es) |
| JP (1) | JP4919565B2 (es) |
| KR (1) | KR100634039B1 (es) |
| CN (1) | CN1155596C (es) |
| AR (1) | AR031526A1 (es) |
| AT (1) | ATE299142T1 (es) |
| AU (1) | AU772189B2 (es) |
| BR (1) | BR0013498A (es) |
| CA (1) | CA2379021C (es) |
| CZ (1) | CZ298533B6 (es) |
| DE (1) | DE60021194T2 (es) |
| DK (1) | DK1212320T3 (es) |
| ES (1) | ES2244469T3 (es) |
| HU (1) | HUP0203194A3 (es) |
| IL (2) | IL148218A0 (es) |
| MX (1) | MXPA02001919A (es) |
| NO (1) | NO321887B1 (es) |
| NZ (1) | NZ517900A (es) |
| PL (1) | PL201178B1 (es) |
| PT (1) | PT1212320E (es) |
| RU (1) | RU2246494C2 (es) |
| SI (1) | SI1212320T1 (es) |
| SK (1) | SK287018B6 (es) |
| TR (1) | TR200200460T2 (es) |
| TW (1) | TWI286136B (es) |
| UA (1) | UA74160C2 (es) |
| WO (1) | WO2001014330A2 (es) |
| ZA (1) | ZA200201829B (es) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2244469T3 (es) | 1999-08-23 | 2005-12-16 | Solvay Pharmaceuticals B.V. | Fenilpiperazinas como inhibidores de la recaptacion de serotonina. |
| AR032712A1 (es) | 2001-02-21 | 2003-11-19 | Solvay Pharm Bv | Un mesilato de derivados de fenilpiperazina y composiciones farmaceuticas que lo contienen |
| AR032711A1 (es) | 2001-02-21 | 2003-11-19 | Solvay Pharm Bv | Derivados de fenilpiperazina, un metodo para la preparacion de los mismos y una composicion farmaceutica que los contiene |
| US7041683B2 (en) | 2001-04-24 | 2006-05-09 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1, 4-benzodiozan |
| WO2002085896A1 (en) * | 2001-04-24 | 2002-10-31 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1,4-benzodioxan |
| US6656950B2 (en) | 2001-04-25 | 2003-12-02 | Wyeth | Antidepressant azaheterocyclylmethyl derivatives of 1,4-dioxino[2,3-b]pyridine |
| AU2002322539B2 (en) | 2001-07-20 | 2007-09-27 | Psychogenics Inc. | Treatment for attention-deficit hyperactivity disorder |
| EP1336406A1 (en) * | 2002-02-14 | 2003-08-20 | Solvay Pharmaceuticals B.V. | Partial dopamine-D2 receptor agonist plus serotonin and/or noradrenaline inhibitory activity |
| CA2485136C (en) * | 2002-05-13 | 2011-12-20 | F. Hoffmann-La Roche Ag | Benzoxazine derivatives as 5-ht6 modulators and uses thereof |
| DE10233500A1 (de) * | 2002-07-24 | 2004-02-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 3-Z-[1-(4-(N-((4-Methyl-piperazin-1-yl)-methylcarbonyl)-N-methyl-amino)-anilino)-1-phenyl-methylen]-6-methoxycarbonyl-2-indolinon-Monoethansulfonat und dessen Verwendung als Arzneimittel |
| JP4401297B2 (ja) * | 2002-11-08 | 2010-01-20 | エフ．ホフマン−ラ ロシュ アーゲー | 置換ベンゾオキサジノン及びその使用 |
| US7276603B2 (en) | 2003-05-02 | 2007-10-02 | Wyeth | Benzofuranyl-and benzothienyl-piperazinyl quinolines and methods of their use |
| WO2004108671A1 (en) * | 2003-06-06 | 2004-12-16 | Suven Life Sciences Limited | Substituted indoles with serotonin receptor affinity, process for their preparation and pharmaceutical compositions containing them |
| CN101072563A (zh) * | 2004-12-07 | 2007-11-14 | 索尔瓦药物有限公司 | 同时对多巴胺－d2受体和5－羟色胺重摄取部位具有亲合力的苯并二噁烷哌嗪衍生物 |
| US7371769B2 (en) | 2004-12-07 | 2008-05-13 | Solvay Pharmaceuticals B.V. | Tetrahydropyridin-4-yl indoles with a combination of affinity for dopamine-D2 receptors and serotonin reuptake sites |
| BRPI0518370A2 (pt) * | 2004-12-07 | 2008-11-18 | Solvay Pharm Bv | composto, composiÇço farmacÊutica, mÉtodo para preparar uma composiÇço, e, uso de um composto |
| US20060122247A1 (en) | 2004-12-08 | 2006-06-08 | Solvay Pharmaceuticals B.V. | Aryloxyethylamine and phenylpiperazine derivatives with a combination of partial dopamine-D2 receptor agonism and serotonin reuptake inhibition |
| ES2317335T3 (es) * | 2004-12-08 | 2009-04-16 | Solvay Pharmaceuticals B.V. | Derivados de fenilpiperazina con una combinacion de agonismo parcial de receptor de dopamina-d2 e inhibicion de la recaptacion de serotonina. |
| GT200600416A (es) | 2005-09-12 | 2007-09-20 | Sales salicilato y gentisato de un compuesto de piperazina | |
| GT200600414A (es) | 2005-09-12 | 2007-09-20 | Sal de glucuranato de compuesto de piperazine | |
| PE20070523A1 (es) * | 2005-09-12 | 2007-06-28 | Wyeth Corp | Formulacion de liberacion sostenida del glucuronato de (8-{4-[3-(5-fluoro-1h-indol-3-il)-propil]-piperazin-1-il}-2-metil-4h-benzo[1,4]oxazin-3-ona |
| US9066903B2 (en) | 2006-02-28 | 2015-06-30 | The United States Of America As Represented By The Department Of Veterans Affairs | Pharmacological treatment of Parkinson's disease |
| FR2941946B1 (fr) * | 2009-02-12 | 2011-03-25 | Sanofi Aventis | Derives de 3-benzofuranyl-indol-2-one-3-acetamidopiperazines substitues, leur preparation et leur application en therapeutique |
| EP2445343B1 (en) * | 2009-06-25 | 2021-08-04 | Alkermes Pharma Ireland Limited | Prodrugs of nh-acidic compounds |
| WO2015014256A1 (en) | 2013-07-29 | 2015-02-05 | Sunshine Lake Pharma Co., Ltd. | Substituted heteroaryl compounds and methods of use thereof |
| WO2016192657A1 (en) | 2015-06-03 | 2016-12-08 | Sunshine Lake Pharma Co., Ltd. | Substituted piperazine compounds and methods of use and use thereof |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1075156A (en) | 1963-08-27 | 1967-07-12 | Luso Farmaco Inst | Substituted piperazines |
| GB8830312D0 (en) * | 1988-12-28 | 1989-02-22 | Lundbeck & Co As H | Heterocyclic compounds |
| DE4127849A1 (de) | 1991-08-22 | 1993-02-25 | Merck Patent Gmbh | Benzodioxanderivate |
| US5314896A (en) | 1991-11-20 | 1994-05-24 | Warner-Lambert Company | 1,3-substituted cycloalkenes and cycloalkanes as central nervous system agents |
| DE4333254A1 (de) * | 1993-09-30 | 1995-04-06 | Merck Patent Gmbh | Piperidine und Piperazine |
| DE4414113A1 (de) | 1994-04-22 | 1995-10-26 | Merck Patent Gmbh | 3-Indolylpiperidine |
| US5576321A (en) | 1995-01-17 | 1996-11-19 | Eli Lilly And Company | Compounds having effects on serotonin-related systems |
| AR004229A1 (es) | 1995-11-06 | 1998-11-04 | Wyeth Corp | Derivados indolalquilo de benzodioxanmetilamina y su uso para preparar medicamentos |
| ZA9711376B (en) | 1996-12-20 | 1998-07-21 | Lundbeck & Co As H | Indole or dihydroindole derivatives |
| DE19730989A1 (de) * | 1997-07-18 | 1999-01-21 | Merck Patent Gmbh | Piperazin-Derivate |
| PT1007523E (pt) * | 1997-07-25 | 2004-02-27 | Lundbeck & Co As H | Derivados indole e 2,3-di-ridroindole, sua preparacao e utilizacao |
| ATE253058T1 (de) * | 1997-09-02 | 2003-11-15 | Duphar Int Res | Piperidin- und piperazin derivate als 5-ht1- rezeptor-agonisten |
| EP0900792B1 (en) | 1997-09-02 | 2003-10-29 | Duphar International Research B.V | Piperazine and piperidine derivatives as 5-HT1A and dopamine D2-receptor (ant)agonists |
| IL139962A0 (en) * | 1998-06-19 | 2002-02-10 | Lundbeck & Co As H | 4,5,6 and 7-indole and indoline derivatives, their preparation and use |
| JP2003521443A (ja) * | 1998-06-19 | 2003-07-15 | ハー・ルンドベック・アクチエゼルスカベット | ４，５，６及び７−インドール及びインドリン誘導体、その製造方法及びその使用方法 |
| AR020773A1 (es) | 1998-10-16 | 2002-05-29 | Duphar Int Res | Compuesto derivados de 3-(tetrahidropiridin-4-il)indol, metodo para prepararlo, una composicion farmaceutica que los contiene, metodo para preparar dicha composicion y uso del compuesto |
| AR022303A1 (es) * | 1999-01-22 | 2002-09-04 | Lundbeck & Co As H | Derivados de piperidina, tetrahidropiridina y piperazina, su preparacion y utilizacion |
| ES2244469T3 (es) | 1999-08-23 | 2005-12-16 | Solvay Pharmaceuticals B.V. | Fenilpiperazinas como inhibidores de la recaptacion de serotonina. |
| AR032712A1 (es) * | 2001-02-21 | 2003-11-19 | Solvay Pharm Bv | Un mesilato de derivados de fenilpiperazina y composiciones farmaceuticas que lo contienen |
| AR032711A1 (es) | 2001-02-21 | 2003-11-19 | Solvay Pharm Bv | Derivados de fenilpiperazina, un metodo para la preparacion de los mismos y una composicion farmaceutica que los contiene |
| EP1336406A1 (en) | 2002-02-14 | 2003-08-20 | Solvay Pharmaceuticals B.V. | Partial dopamine-D2 receptor agonist plus serotonin and/or noradrenaline inhibitory activity |
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2000
- 2000-08-22 ES ES00962355T patent/ES2244469T3/es not_active Expired - Lifetime
- 2000-08-22 JP JP2001518420A patent/JP4919565B2/ja not_active Expired - Fee Related
- 2000-08-22 PL PL364821A patent/PL201178B1/pl not_active IP Right Cessation
- 2000-08-22 TR TR2002/00460T patent/TR200200460T2/xx unknown
- 2000-08-22 AU AU74118/00A patent/AU772189B2/en not_active Ceased
- 2000-08-22 WO PCT/EP2000/008190 patent/WO2001014330A2/en not_active Ceased
- 2000-08-22 SK SK249-2002A patent/SK287018B6/sk not_active IP Right Cessation
- 2000-08-22 CA CA002379021A patent/CA2379021C/en not_active Expired - Fee Related
- 2000-08-22 IL IL14821800A patent/IL148218A0/xx active IP Right Grant
- 2000-08-22 CN CNB008118655A patent/CN1155596C/zh not_active Expired - Fee Related
- 2000-08-22 BR BR0013498-8A patent/BR0013498A/pt active Search and Examination
- 2000-08-22 MX MXPA02001919A patent/MXPA02001919A/es active IP Right Grant
- 2000-08-22 NZ NZ517900A patent/NZ517900A/en not_active IP Right Cessation
- 2000-08-22 DE DE60021194T patent/DE60021194T2/de not_active Expired - Lifetime
- 2000-08-22 RU RU2002107318/04A patent/RU2246494C2/ru not_active IP Right Cessation
- 2000-08-22 HU HU0203194A patent/HUP0203194A3/hu unknown
- 2000-08-22 SI SI200030720T patent/SI1212320T1/xx unknown
- 2000-08-22 PT PT00962355T patent/PT1212320E/pt unknown
- 2000-08-22 US US10/069,256 patent/US7067513B1/en not_active Expired - Fee Related
- 2000-08-22 AR ARP000104326A patent/AR031526A1/es active IP Right Grant
- 2000-08-22 DK DK00962355T patent/DK1212320T3/da active
- 2000-08-22 UA UA2002032313A patent/UA74160C2/uk unknown
- 2000-08-22 KR KR1020027002242A patent/KR100634039B1/ko not_active Expired - Fee Related
- 2000-08-22 CZ CZ20020619A patent/CZ298533B6/cs not_active IP Right Cessation
- 2000-08-22 AT AT00962355T patent/ATE299142T1/de active
- 2000-08-22 EP EP00962355A patent/EP1212320B1/en not_active Expired - Lifetime
- 2000-09-01 TW TW089117890A patent/TWI286136B/zh not_active IP Right Cessation
-
2002
- 2002-02-18 IL IL148218A patent/IL148218A/en not_active IP Right Cessation
- 2002-02-19 NO NO20020810A patent/NO321887B1/no not_active IP Right Cessation
- 2002-03-05 ZA ZA200201829A patent/ZA200201829B/xx unknown
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2006
- 2006-06-12 US US11/450,323 patent/US7456182B2/en not_active Expired - Fee Related
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2008
- 2008-10-27 US US12/258,591 patent/US7605162B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
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