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AR035564A1 - Moduladores selectivos de receptores de estrogenos en combinacion con estrogenos - Google Patents

Moduladores selectivos de receptores de estrogenos en combinacion con estrogenos

Info

Publication number
AR035564A1
AR035564A1 ARP010100372A ARP010100372A AR035564A1 AR 035564 A1 AR035564 A1 AR 035564A1 AR P010100372 A ARP010100372 A AR P010100372A AR P010100372 A ARP010100372 A AR P010100372A AR 035564 A1 AR035564 A1 AR 035564A1
Authority
AR
Argentina
Prior art keywords
administration
strogens
strogen
receivers
combination
Prior art date
Application number
ARP010100372A
Other languages
English (en)
Original Assignee
Endorech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Endorech Inc filed Critical Endorech Inc
Publication of AR035564A1 publication Critical patent/AR035564A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Métodos novedosos para reducir o eliminar la incidencia de accesos de calor y síntomas menopáusicos, que al mismo tiempo disminuyen el riesgo de adquirir cáncer de mama o de endometrio y para tratar y/o inhibir además el desarrollo de osteoporosis, hipercolesterolemia, hiperlipidemia, ateroesclerosis, hipertensión, resistencia a insulina, diabetes, pérdida de masa muscular, obesidad, irregularidades menstruales, enfermedad de Alzheimer o sequedad vaginal en animales de sangre caliente susceptibles, inclusive seres humanos que comprende la administración de un modulador selectivo de receptores de estrógeno, en particular compuestos que presentan la estructura general (1) y una cantidad de un estrógeno o un compuesto estrogénico / androgénico mixto. Además, se describe específicamente la administración de bifosfonatos, progestágeno o un precursor de esteroides sexuales para el tratamiento médico y/o la inhibición de algunas de las enfermedades mencionadas anteriormente. También se describen composiciones farmacéuticas para la distribución del o de los ingredientes activos y uno o varios conjuntos de elementos (''kits'') de utilidad para la presente.
ARP010100372A 2000-01-28 2001-01-26 Moduladores selectivos de receptores de estrogenos en combinacion con estrogenos AR035564A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17860100P 2000-01-28 2000-01-28

Publications (1)

Publication Number Publication Date
AR035564A1 true AR035564A1 (es) 2004-06-16

Family

ID=22653187

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010100372A AR035564A1 (es) 2000-01-28 2001-01-26 Moduladores selectivos de receptores de estrogenos en combinacion con estrogenos

Country Status (21)

Country Link
US (3) US20030040510A1 (es)
EP (1) EP1251855A1 (es)
JP (1) JP2003520817A (es)
KR (1) KR20020073566A (es)
CN (1) CN1400904A (es)
AR (1) AR035564A1 (es)
AU (1) AU2991301A (es)
BR (1) BR0108107A (es)
CA (1) CA2395730A1 (es)
CZ (1) CZ20022401A3 (es)
HK (1) HK1048761A1 (es)
HU (1) HUP0204211A3 (es)
IL (1) IL149990A0 (es)
MX (1) MXPA02007165A (es)
NO (1) NO20023484L (es)
NZ (1) NZ534348A (es)
PL (1) PL357163A1 (es)
RU (1) RU2342145C2 (es)
SK (1) SK9592002A3 (es)
WO (1) WO2001054699A1 (es)
ZA (1) ZA200205926B (es)

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Also Published As

Publication number Publication date
EP1251855A1 (en) 2002-10-30
MXPA02007165A (es) 2003-09-22
RU2002123047A (ru) 2004-03-10
NO20023484D0 (no) 2002-07-22
US20030065008A1 (en) 2003-04-03
KR20020073566A (ko) 2002-09-27
CN1400904A (zh) 2003-03-05
RU2342145C2 (ru) 2008-12-27
AU2991301A (en) 2001-08-07
BR0108107A (pt) 2003-03-11
NZ534348A (en) 2006-06-30
SK9592002A3 (en) 2003-12-02
HK1048761A1 (zh) 2003-04-17
HUP0204211A3 (en) 2005-06-28
WO2001054699A1 (en) 2001-08-02
PL357163A1 (en) 2004-07-26
CA2395730A1 (en) 2001-08-02
JP2003520817A (ja) 2003-07-08
IL149990A0 (en) 2002-12-01
HUP0204211A2 (hu) 2003-04-28
ZA200205926B (en) 2003-07-24
CZ20022401A3 (cs) 2003-10-15
US20020198179A1 (en) 2002-12-26
US20030040510A1 (en) 2003-02-27
NO20023484L (no) 2002-07-22

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